keyword
MENU ▼
Read by QxMD icon Read
search

Transference

keyword
https://www.readbyqxmd.com/read/27926995/frozen-but-no-accident-why-the-20-standard-amino-acids-were-selected
#1
REVIEW
Andrew J Doig
The 20 standard amino acids encoded by the Genetic Code were adopted during the RNA World, around 4 billion years ago. This amino acid set could be regarded as a frozen accident, implying that other possible structures could equally well have been chosen to use in proteins. Amino acids were not primarily selected for their ability to support catalysis, since the RNA World already had highly effective cofactors to perform reactions, such as oxidation, reduction and transfer of small molecules. Rather, they were selected to enable the formation of soluble structures with close-packed cores, allowing the presence of ordered binding pockets...
December 7, 2016: FEBS Journal
https://www.readbyqxmd.com/read/27926971/management-of-endometriomas
#2
Ludovico Muzii, Chiara Di Tucci, Mara Di Feliciantonio, Giulia Galati, Ludovica Verrelli, Violante Di Donato, Claudia Marchetti, Pierluigi Benedetti Panici
Ovarian endometriomas affect 17 to 44% of women with endometriosis, and are often associated with pelvic pain and infertility. Treatment options include expectant management, medical and/or surgical treatment, and in vitro fertilization and embryo transfer (IVF-ET). The choice of treatment depends mostly on the associated symptoms. In most cases, surgery is the preferred choice, since endometriomas do not respond to medical treatment, which may only treat associated pain. In case of infertility, IVF-ET may be a suitable alternative to surgery, particularly when there is no associated pain...
December 7, 2016: Seminars in Reproductive Medicine
https://www.readbyqxmd.com/read/27926922/high-speed-mouse-backcrossing-through-the-female-germ-line
#3
Erin Grove, Sigrid Eckardt, K John McLaughlin
Transferring mouse mutations into specific mouse strain backgrounds can be critical for appropriate analysis of phenotypic effects of targeted genomic alterations and quantitative trait loci. Speed congenic breeding strategies incorporating marker-assisted selection of progeny with the highest percentage target background as breeders for the next generation can produce congenic strains within approximately 5 generations. When mating selected donor males to target strain females, this may require more than 1 year, with each generation lasting 10 to 11 weeks including 3 weeks of gestation and 7 to 8 weeks until the males reach sexual maturity...
2016: PloS One
https://www.readbyqxmd.com/read/27926680/humeral-retroversion-in-children-with-shoulder-internal-rotation-contractures-secondary-to-upper-trunk-neonatal-brachial-plexus-palsy
#4
Michael L Pearl, Michael Batech, Fabian van de Bunt
BACKGROUND: The most common sequela of neonatal brachial plexus palsy is an internal rotation contracture of the shoulder that impairs function and leads to skeletal deformation of the glenohumeral joint. Treatment options include release, transfers, and humeral osteotomy, all ultimately striving for better function through increased external rotation. Prior studies have shown that neonatal brachial plexus palsy alters humeral retroversion but with conflicting findings. We studied retroversion in children with internal rotation contractures from neonatal brachial plexus palsy to clarify its effect on version and surgical planning...
December 7, 2016: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/27926676/long-term-restoration-of-anterior-shoulder-stability-a-retrospective-analysis-of-arthroscopic-bankart-repair-versus-open-latarjet-procedure
#5
Stefan M Zimmermann, Max J Scheyerer, Mazda Farshad, Sabrina Catanzaro, Stefan Rahm, Christian Gerber
BACKGROUND: Various operative techniques are used for treating recurrent anterior shoulder instability, and good mid-term results have been reported. The purpose of this study was to compare shoulder stability after treatment with the 2 commonly performed procedures, the arthroscopic Bankart soft-tissue repair and the open coracoid transfer according to Latarjet. METHODS: A comparative, retrospective case-cohort analysis of 360 patients (364 shoulders) who had primary repair for recurrent anterior shoulder instability between 1998 and 2007 was performed...
December 7, 2016: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/27926382/prediction-of-anti-cancer-drug-response-by-kernelized-multi-task-learning
#6
Mehmet Tan
MOTIVATION: Chemotherapy or targeted therapy are two of the main treatment options for many types of cancer. Due to the heterogeneous nature of cancer, the success of the therapeutic agents differs among patients. In this sense, determination of chemotherapeutic response of the malign cells is essential for establishing a personalized treatment protocol and designing new drugs. With the recent technological advances in producing large amounts of pharmacogenomic data, in silico methods have become important tools to achieve this aim...
October 2016: Artificial Intelligence in Medicine
https://www.readbyqxmd.com/read/27925861/modeling-heavy-ion-impairment-of-hippocampal-neurogenesis-after-acute-and-fractionated-irradiation
#7
Eliedonna Cacao, Francis A Cucinotta
Radiation-induced impairment of neurogenesis in the hippocampal dentate gyrus is a concern due to its reported association with cognitive detriments after radiotherapy for brain cancers and the possible risks to astronauts chronically exposed to space radiation. Here, we have extended our recent work in a mouse model of impaired neurogenesis after exposure to low-linear energy transfer (LET) heavy ion radiation. To our knowledge, this is the first report of a predictive mathematical model of radiation-induced changes to neurogenesis for a variety of radiation types after acute or fractionated irradiation...
December 7, 2016: Radiation Research
https://www.readbyqxmd.com/read/27925698/frustrated-lewis-pairs-like-reactivity-of-rare-earth-metal-complexes-1-4-addition-reactions-and-polymerizations-of-conjugated-polar-alkenes
#8
Pengfei Xu, Yingming Yao, Xin Xu
Three rare-earth aryloxide ion pairs ([L1REOAr]+[B(C6F5)4]-; L1 = CH3C(2,6-iPr2C6H3N)CHC(CH3)(NCH2CH2PPh2); RE = Sc, Y, Lu; Ar = 2,6-tBu2C6H3) are reported, which feature RE/P combinations exhibiting frustrated Lewis pair (FLP)-like 1,4-addition reactions towards conjugated carbonyl substrates e.g. enone, ynone and acrylic substrates. Furthermore, these RE/P complexes are found to be effective catalysts for polymerizations of conjugated polar alkene monomers. Mechanistic studies reveal that the polymerizations are initiated by novel FLP-type 1,4-additions, rather than traditional and ubiquitous covalent RE-E (E = H, C, N, etc...
December 7, 2016: Chemistry: a European Journal
https://www.readbyqxmd.com/read/27925667/tracking-the-activity-of-mtorc1-in-living-cells-using-genetically-encoded-fret-based-biosensor-torcar
#9
Xin Zhou, Simin Li, Jin Zhang
Mechanistic target of rapamycin complex 1 (mTORC1) is a highly conserved serine/threonine protein kinase that responds to multiple distinct signals (e.g., growth factors, amino acids, stress, and energy level) and coordinates cell growth and proliferation. The underlying molecular mechanisms by which these stimuli regulate the activity of mTORC1 are still not fully understood. The spatial compartmentalization of mTORC1 signaling has been suggested as an important mechanism for mTORC1 to achieve the signal specificity and efficiency...
December 7, 2016: Current Protocols in Chemical Biology
https://www.readbyqxmd.com/read/27925585/using-contact-forces-and-robot-arm-accelerations-to-automatically-rate-surgeon-skill-at-peg-transfer
#10
Jeremy Brown, Conor O'Brien, Sarah Leung, Kristoffel Dumon, David Lee, Katherine Kuchenbecker
OBJECTIVE: Most trainees begin learning robotic minimally invasive surgery by performing inanimate practice tasks with clinical robots such as the Intuitive Surgical da Vinci. Expert surgeons are commonly asked to evaluate these performances using standardized five-point rating scales, but doing such ratings is time consuming, tedious, and somewhat subjective. This article presents an automatic skill evaluation system that analyzes only the contact force with the task materials, the broad-bandwidth accelerations of the robotic instruments and camera, and the task completion time...
December 2, 2016: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/27925576/comparison-of-oxygen-transfer-parameters-and-oxygen-demands-in-bioreactors-operated-at-low-and-high-dissolved-oxygen-levels
#11
Richard O Mines, Matthew C Callier, Benjamin J Drabek, André J Butler
The proper design of aeration systems for bioreactors is critical since it can represent up to 50% of the operational and capital cost at water reclamation facilities. Transferring the actual amount of oxygen needed to meet the oxygen demand of the wastewater requires α- and β-factors, which are used for calculating the actual oxygen transfer rate (AOTR) under process conditions based on the standard oxygen transfer rate (SOTR). The SOTR is measured in tap water at 20°C, 1 atmospheric pressure, and 0 mg L(-1) of dissolved oxygen (DO)...
December 7, 2016: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
https://www.readbyqxmd.com/read/27925460/nir-mediated-nanohybrids-of-upconversion-nanophosphors-and-fluorescent-conjugated-polymers-for-high-efficiency-antibacterial-performance-based-on-fluorescence-resonance-energy-transfer
#12
Junting Li, Qi Zhao, Feng Shi, Chenghui Liu, Yanli Tang
A novel nanohybrid comprised of upconversion nanophosphors (UCNPs) and fluorescent conjugated polymers (PFVCN) is rationally fabricated. The new UCNP/PFVCN nanohybrids combine the excellent antibacterial ability of PFVCN and the near IR (NIR) absorbing property of UCNPs, which allows for NIR-mediated antibacterial through the effective fluorescence resonance energy transfer from UCNPs to PFVCN accompanied with generation of reactive oxygen species to kill bacteria.
December 2016: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/27925443/graphene-fe3o4-nanocomposites-as-efficient-anodes-to-boost-the-lifetime-and-current-output-of-microbial-fuel-cells
#13
Rong-Bin Song, Cui-E Zhao, Pan-Pan Gai, Dan Guo, Li-Ping Jiang, Qichun Zhang, Jianrong Zhang, Jun-Jie Zhu
Enhancing microbial activity and electrocatalysis through new anode material design is essential for developing microbial fuel cells (MFCs) with longer lifetimes and higher output. In this research, a novel anode material, graphene/Fe3O4 (G/Fe3O4) composite, has been designed for Shewanella-inoculated MFCs. Because Shewanella species could bind to Fe3O4 with high affinity and their growth could be well supported by Fe3O4, the bacterial cells attached quickly onto the anode surface, and their long-term activity improved...
December 7, 2016: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/27925413/mechanism-of-water-oxidation-catalysed-by-a-mononuclear-manganese-complex-py2n-tbu-2mn-h2o-2-2
#14
Yingying Li, Ke Ye, Per E M Siegbahn, Rong-Zhen Liao
The design and synthesis of biomimetic Mn complexes to catalyze oxygen evolution is a very appealing goal since water oxidation in nature employs manganese. A mononuclear Mn complex 1 [LMnII(H2O)2]2+ (L=Py2N(tBu)2) was recently reported to catalyze water oxidation electrochemically with an applied potential of 1.23 V at pH=12.2 in aqueous solution. Density functional calculations have here been performed to elucidate the mechanism of water oxidation promoted by this catalyst. The calculations showed that 1 can readily lose two protons and one electron with the production of 2 [LMnIII(OH)2]+, which then undergoes two sequential proton-coupled electron transfer processes to afford 4 [LMnVOO]+...
December 7, 2016: ChemSusChem
https://www.readbyqxmd.com/read/27925392/environmental-and-maternal-factors-associated-with-gross-placental-morphology-in-dairy-cattle
#15
M M Kamal, M Van Eetvelde, L Vandaele, G Opsomer
This article reports on a study of gross placental morphology of 282 expelled placentas from 89 primi- and 193 multiparous Holstein dams immediately after calving and examines associations with environmental factors such as typical herd features and season of calving, and maternal factors such as age at calving, level of milk yield at conception and cumulative amount of milk produced during gestation. The highest correlation between calf measurements and placental characteristics was found between the weight of the calf and the total cotyledonary surface (r = ...
December 7, 2016: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/27925363/synthesis-of-discrete-oligomers-by-sequential-pet-raft-single-unit-monomer-insertion
#16
Jiangtao Xu, Changkui Fu, Sivaprakash Shanmugam, Craig J Hawker, Graeme Moad, Cyrille Boyer
Uniform synthetic polymers with precisely defined molar mass and monomer sequence (primary structure) have many potential high-value applications. However, a robust and versatile synthetic strategy for these materials remains one of the great challenges in polymer synthesis. Herein we describe proof-of-principle experiments for a modular strategy to produce discrete oligomers by a visible-light-mediated radical chain process. We utilize the high selectivity provided by photo-induced electron/energy transfer (PET) activation to develop efficient single unit monomer insertion (SUMI) into reversible addition-fragmentation chain-transfer (RAFT) agents...
December 7, 2016: Angewandte Chemie
https://www.readbyqxmd.com/read/27925360/hierarchical-mesoporous-sno2-nanosheets-on-carbon-cloth-a-robust-and-flexible-electrocatalyst-for-co2-reduction-with-high-efficiency-and-selectivity
#17
Fengwang Li, Lu Chen, Gregory P Knowles, Douglas R MacFarlane, Jie Zhang
Electrochemical reduction of CO2 into liquid fuels is a promising approach to achieve a carbon-neutral energy cycle. However, conventional electrocatalysts usually suffer from low energy efficiency and poor selectivity and stability. A 3D hierarchical structure composed of mesoporous SnO2 nanosheets on carbon cloth is proposed to efficiently and selectively electroreduce CO2 to formate in aqueous media. The electrode is fabricated by a facile combination of hydrothermal reaction and calcination. It exhibits an unprecedented partial current density of about 45 mA cm(-2) at a moderate overpotential (0...
December 7, 2016: Angewandte Chemie
https://www.readbyqxmd.com/read/27925347/a-hydrogen-bonded-cyanide-bridged-co2-fe2-square-complex-exhibiting-a-three-step-spin-transition
#18
Masayuki Nihei, Yuta Yanai, I-Jui Hsu, Yoshihiro Sekine, Hiroki Oshio
Co-crystallization of a cyanide-bridged tetranuclear complex [Co2 Fe2 ] with 4-cyanophenol (CP) gave a hydrogen bonding donor-acceptor system, [Co2 Fe2 (bpy*)4 (CN)6 (tp*)2 ](PF6 )2 ⋅2 CP⋅8 BN (1). 1 exhibited a three-step phase transition between HT, IM1, IM2, and LT phases upon temperature variation. Variable temperature magnetic measurements and structural analyses revealed that the three-step spin transition is caused by electron-transfer-coupled spin transitions (ETCSTs) accompanied with alteration of the hydrogen bonding interactions...
December 7, 2016: Angewandte Chemie
https://www.readbyqxmd.com/read/27925316/functional-species-encapsulated-in-nitrogen-doped-porous-carbon-as-a-highly-efficient-catalyst-to-oxygen-reduction-reaction
#19
Li Song, Tao Wang, Yiou Ma, Hairong Xue, Hu Guo, Xiaoli Fan, Wei Xia, Hao Gong, Jianping He
The scarcity, high cost and poor stability of precious metal-based electrocatalysts have stimulated the development of novel non-precious metal catalysts to oxygen reduction reaction (ORR) for the use in fuel cells and metal-air batteries. Here, we in-situ fabricated a hybrid material (Co-W-C/N) with functional species (tungsten carbide and cobalt nanoparticles) encapsulated in N-doped porous carbon framework, through a facile multi-constituents co-assembly method combined with subsequent annealing treatment...
December 7, 2016: Chemistry: a European Journal
https://www.readbyqxmd.com/read/27925306/graphene-oxide-based-enzyme-nanoarchitectonics-for-substrate-channeling
#20
Motilal Mathesh, Jingquan Liu, Colin J Barrow, Wenrong Yang
The controlled spatial organization or compartmentalization of multi-enzyme cascade reactions to transfer a substrate from one enzyme to another for substrate channeling on scaffolds has sparked increasing interest in recent years. Here, we use graphene oxides to study the dependence of the activity of cascade reactions in a closely packed, randomly immobilized enzyme system on a 2 D scaffold. We first observe that the hydrophobicity of graphene oxides and various enzyme architectures for co-immobilized systems are important attributes for achieving high product-conversion rates...
December 7, 2016: Chemistry: a European Journal
keyword
keyword
10053
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"