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Keywords charlson comorbidity index, de...

charlson comorbidity index, delirium

https://read.qxmd.com/read/36911570/common-biomarkers-associated-with-delirium-in-hospitalized-patients-with-covid-19-at-the-epicentre-of-turkish-coronavirus-outbreak-a-case-control-study
#21
JOURNAL ARTICLE
Süleyman Dönmezler, Aybegüm Uysal, İmren Kurt, Damla Özmen, Oya Güçlü, Yavuz Altunkaynak
INTRODUCTION: To investigate the differences in biochemical characteristics between Coronavirus Disease 2019 (COVID-19) patients with and without delirium in non-intensive care (IC) COVID-19 units was aimed. METHODS: This study was designed as an observational, single-centered, and case-control study consisting of 43 delirious patients and matched 45 non-delirious patients admitted to non-IC COVID-19 units. Delirium was diagnosed by a consultant psychiatrist according to the DSM-5 delirium diagnostic criteria...
2023: Noro Psikiyatri Arsivi
https://read.qxmd.com/read/36749454/atypical-presentation-of-covid-19-in-older-patients-is-associated-with-frailty-but-not-with-adverse-outcomes
#22
JOURNAL ARTICLE
Joy E van Son, Elisabeth C P Kahn, Jessica M van der Bol, Dennis G Barten, Laura C Blomaard, Carmen van Dam, Jacobien Ellerbroek, Steffy W M Jansen, Anita Lekx, Carolien M J van der Linden, Roy Looman, Huub A A M Maas, Francesco U S Mattace-Raso, Simon P Mooijaart, Barbara C van Munster, Annefleur Peters, Harmke A Polinder-Bos, Rosalinde A L Smits, Petra E Spies, Anna Wassenburg, Nora Wassenburg, Hanna C Willems, Henrike J Schouten, Sarah H M Robben
PURPOSE: Older patients with COVID-19 can present with atypical complaints, such as falls or delirium. In other diseases, such an atypical presentation is associated with worse clinical outcomes. However, it is not known whether this extends to COVID-19. We aimed to study the association between atypical presentation of COVID-19, frailty and adverse outcomes, as well as the incidence of atypical presentation. METHODS: We conducted a retrospective observational multi-center cohort study in eight hospitals in the Netherlands...
February 7, 2023: European Geriatric Medicine
https://read.qxmd.com/read/36721263/integrated-postoperative-care-model-for-older-colorectal-surgery-patients-improves-outcomes-and-reduces-healthcare-costs
#23
JOURNAL ARTICLE
Sevdenur Cizginer, Eian G Prohl, Joao Filipe G Monteiro, Ferhat Yildiz, Richard N Jones, Steven Schechter, Robert Patterson, Adam Klipfel, Mark Richard Katlic, Lori A Daiello, Nadia Mujahid, Iva Neupane, William G Cioffi, Maria Ducharme, Matthew D Vrees, Lynn McNicoll
BACKGROUND: Older surgical patients have an increased risk for postoperative complications, driving up healthcare costs. We determined if postoperative co-management of older surgery patients is associated with postoperative outcomes and hospital costs. METHODS: Retrospective data were collected for patients ≥70 years old undergoing colorectal surgery at a community teaching hospital. Patient outcomes were compared between those receiving postoperative surgery co-management care through the Optimization of Senior Care and Recovery (OSCAR) program and controls who received standard of care...
May 2023: Journal of the American Geriatrics Society
https://read.qxmd.com/read/36655317/risk-factors-and-consequences-of-post-esophagectomy-delirium-a-systematic-review-and-meta-analysis
#24
JOURNAL ARTICLE
Dimitrios Papaconstantinou, Maximos Frountzas, Jelle P Ruurda, Stella Mantziari, Diamantis I Tsilimigras, Nikolaos Koliakos, Georgios Tsivgoulis, Dimitrios Schizas
Post-operative delirium (POD) is a state of mental and neurocognitive impairment characterized by disorientation and fluctuating levels of consciousness. POD in the context of esophageal surgery may herald serious and potentially life-threatening post-operative complications, or conversely be a symptom of severe underlying pathophysiologic disturbances. The aim of the present systematic review and meta-analysis is to explore risk factors associated with the development of POD and assess its impact on post-operative outcomes...
January 18, 2023: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://read.qxmd.com/read/36581418/clinical-risk-analysis-of-postoperative-delirium-in-elderly-patients-undergoing-thoracic-and-abdominal-surgery-study-protocol-of-a-single-centre-observational-cohort-study
#25
JOURNAL ARTICLE
Jing Liu, Meinv Liu, Jianli Li, Junfang Rong
INTRODUCTION: Postoperative delirium (POD) acts as a common complication in older patients after surgery, accompanied by longer recovery time, prolonged hospital stay, increased hospitalisation costs, etc. Therefore, it is urgent to reduce POD by implementing some intervention strategies. Early identification of associated risk factors was regarded as an effective method to lower the incidence of POD. Currently, the incidence and risk factors of POD have been widely investigated in orthopaedic and cardiac surgery, while remain scarce in thoracic and abdominal surgery...
December 29, 2022: BMJ Open
https://read.qxmd.com/read/36431107/postoperative-delirium-after-reconstructive-surgery-in-the-head-and-neck-region
#26
JOURNAL ARTICLE
Juergen Taxis, Steffen Spoerl, Andreas Broszio, Jonas Eichberger, Elisabeth Grau, Johannes Schuderer, Nils Ludwig, Maximilian Gottsauner, Gerrit Spanier, Annika Bundscherer, Torsten E Reichert, Tobias Ettl
Postoperative delirium (POD) is an acute and serious complication following extended surgery. The aim of this study was to identify possible risk factors and scores associated with POD in patients undergoing reconstructive head and neck surgery. A collective of 225 patients was retrospectively evaluated after receiving reconstructive surgery in the head and neck region, between 2013 to 2018. The incidence of POD was examined with regards to distinct patient-specific clinical as well as perioperative parameters...
November 9, 2022: Journal of Clinical Medicine
https://read.qxmd.com/read/36423306/frailty-comorbidity-and-associations-with-in-hospital-mortality-in-older-covid-19-patients-an-exploratory-study-of-administrative-data
#27
JOURNAL ARTICLE
Johannes Heyl, Flavien Hardy, Katie Tucker, Adrian Hopper, Maria J M Marchã, Annakan V Navaratnam, Tim Wr Briggs, Jeremy Yates, Jamie Day, Andrew Wheeler, Sue Eve-Jones, William K Gray
BACKGROUND: Older adults have worse outcomes following hospitalisation with COVID-19, but within this group there is substantial variation. Although frailty and comorbidity are key determinants of mortality, it is less clear which specific manifestations of frailty and comorbidity are associated with the worst outcomes. OBJECTIVE: We aimed to identify the key comorbidities and domains of frailty that were associated with in-hospital mortality in older patients with COVID-19 using models developed using machine learning algorithms...
November 24, 2022: Interactive Journal of Medical Research
https://read.qxmd.com/read/36273712/postoperative-delirium-in-patients-receiving-hip-bipolar-hemiarthroplasty-for-displaced-femoral-neck-fractures-the-risk-factors-and-further-clinical-outcomes
#28
JOURNAL ARTICLE
Deng Horng Lee, Chih-Hsun Chang, Chih-Wei Chang, Yi-Chen Chen, Ta-Wei Tai
BACKGROUND: Postoperative delirium in patients who have hip fractures may lead to poor outcomes. This study aimed to determine perioperative risk factors and clinical outcomes of postoperative delirium in patients undergoing hip bipolar hemiarthroplasty for displaced femoral neck fractures. METHODS: Among 1,353 patients who underwent hemiarthroplasty at our institution during 2013-2021, we identified 78 patients with postoperative delirium diagnosed with the confusion assessment method...
October 21, 2022: Journal of Arthroplasty
https://read.qxmd.com/read/36233496/forecasting-postoperative-delirium-in-older-adult-patients-with-fast-and-frugal-decision-trees
#29
JOURNAL ARTICLE
Maria Heinrich, Jan K Woike, Claudia D Spies, Odette Wegwarth
Postoperative delirium (POD) is associated with increased complication and mortality rates, particularly among older adult patients. However, guideline recommendations for POD detection and management are poorly implemented. Fast-and-frugal trees (FFTrees), which are simple prediction algorithms, may be useful in this context. We compared the capacity of simple FFTrees with two more complex models-namely, unconstrained classification trees (UDTs) and logistic regression (LogReg)-for the prediction of POD among older surgical patients in the perioperative setting...
September 24, 2022: Journal of Clinical Medicine
https://read.qxmd.com/read/36161628/delirium-dementia-and-depression-3d-assessment-of-older-patients-in-the-emergency-department-5-year-survival-analysis
#30
JOURNAL ARTICLE
İsa Kılıçaslan, Myat Soe Thet, Berkay Karahacıoğlu, Merve Sevim, Zekeriya Ülger, Mehmet Ali Aslaner, Banu Kılıçaslan
BACKGROUND: While physicians tend to emphasize on physical medical problems, behavioral and cognitive disorders of geriatric patients are usually missed, especially in emergency settings. The aim of the study was to determine the prevalence of delirium, dementia, and depression (3D) among older patients (≥65 years old) in the Emergency Department (ED) and to evaluate the effect of geriatric 3D on the 6-month and 5-year mortality. METHODS: This was a prospective, observational cohort study, including 415 patients from eligible 512 consecutive older patients, who are 65 years of age or older, presenting to the ED of a tertiary care university hospital...
April 2022: Turkish Journal of Medical Sciences
https://read.qxmd.com/read/36128514/paternal-occupation-and-delirium-risk-in-older-adults-a-potential-marker-of-early-life-exposures
#31
JOURNAL ARTICLE
Haley M Shiff, Franchesca Arias, Alyssa B Dufour, Deborah Carr, Fan Chen, Yun Gou, Richard Jones, Eva Schmitt, Thomas G Travison, Zachary J Kunicki, Olivia I Okereke, Sharon K Inouye
Background and Objectives: Delirium is a common disorder among older adults following hospitalization or major surgery. Whereas many studies examine the risk of proximate exposures and comorbidities, little is known about pathways linking childhood exposures to later-life delirium. In this study, we explored the association between paternal occupation and delirium risk. Research Design and Methods: A prospective observational cohort study of 528 older adults undergoing elective surgery at two academic medical centers...
2022: Innovation in Aging
https://read.qxmd.com/read/36114455/association-of-cholinesterase-activities-and-pod-in-older-adult-abdominal-surgical-patients
#32
MULTICENTER STUDY
Zdravka Bosancic, Claudia D Spies, Anika Müller, Georg Winterer, Sophie K Piper, Maria Heinrich
BACKGROUND: Postoperative delirium (POD) is a frequent complication after surgery. Older adult patients undergoing abdominal surgery are at higher risk for developing POD. Studies on the association of cholinesterase activities and POD are rare, but leading hypotheses implicate that the cholinergic pathway might play an important role in neuroinflammation and development of POD. The objective of this study was to figure out if there is an association between the development of POD and acetyl- and butyrylcholinesterase (AChE and BuChE) activities in older adult patients undergoing abdominal surgery...
September 16, 2022: BMC Anesthesiology
https://read.qxmd.com/read/36062155/the-age-adjusted-charlson-comorbidity-index-predicts-post-operative-delirium-in-the-elderly-following-thoracic-and-abdominal-surgery-a-prospective-observational-cohort-study
#33
JOURNAL ARTICLE
Jing Liu, Jianli Li, Jinhua He, Huanhuan Zhang, Meinv Liu, Junfang Rong
Background: Post-operative delirium (POD) presents as a serious neuropsychiatric syndrome in the elderly undergoing thoracic and abdominal surgery, which is mostly associated with poor prognosis. The Age-adjusted Charlson Comorbidity Index (ACCI) has been widely recognized as an independently predictive factor for overall survival rate and mortality in various surgeries. However, no studies demonstrated the potential relationship between ACCI and POD. The current study was to explore the correlation between ACCI and POD, and determine the predictive effect of ACCI on POD in the elderly after thoracic and abdominal surgery...
2022: Frontiers in Aging Neuroscience
https://read.qxmd.com/read/36061065/derivation-and-validation-of-a-prediction-score-for-postoperative-delirium-in-geriatric-patients-undergoing-hip-fracture-surgery-or-hip-arthroplasty
#34
JOURNAL ARTICLE
Jiawei Shen, Youzhong An, Baoguo Jiang, Peixun Zhang
Introduction: Postoperative delirium is a common complication of patients undergoing hip fracture surgery or arthroplasty and is related to decreased survival time and physical function. In this study, we aim to build and validate a prediction score of postoperative delirium in geriatric patients undergoing hip fracture surgery or hip arthroplasty. Methods: A retrospective cohort of geriatric patients undergoing hip fracture surgery or hip arthroplasty was established...
2022: Frontiers in Surgery
https://read.qxmd.com/read/36041906/risk-factors-and-effect-of-postoperative-delirium-on-adverse-surgical-outcomes-in-older-adults-after-elective-abdominal-cancer-surgery-in-taiwan
#35
JOURNAL ARTICLE
Cheng-Chou Lai, Keng-Hao Liu, Chun-Yi Tsai, Jun-Te Hsu, Shun-Wen Hsueh, Chia-Yen Hung, Wen-Chi Chou
BACKGROUND: Postoperative delirium (POD) is a common complication in older adults, with unknown epidemiology and effects on surgical outcomes in Asian geriatric cancer patients. This study evaluated incidence, risk factors, and association between adverse surgical outcomes and POD after intra-abdominal cancer surgery in Taiwan. METHODS: Overall, 345 patients aged ≥65 years who underwent elective abdominal cancer surgery at a medical center in Taiwan were prospectively enrolled...
August 27, 2022: Asian Journal of Surgery
https://read.qxmd.com/read/36008359/site-of-care-and-factors-associated-with-mortality-in-unvaccinated-australian-aged-care-residents-during-covid-19-outbreaks
#36
JOURNAL ARTICLE
Nicholas J Radcliffe, Liza Lau, Emma Hack, Andrew Huynh, Arvind Puri, Henry Yao, Aaron Wong, Sabrina Kohler, Maggie Chua, Sanka Amadoru, Cilla Haywood, Paul Yates
BACKGROUND: Residential InReach presents an alternative to hospital admission for aged care residents swabbed for coronavirus disease 2019 (COVID-19), although relative outcomes remain unknown. AIMS: To compare rates and predictors of 28-day mortality for aged care residents seen by InReach with COVID-19, or 'suspected COVID-19' (sCOVID), including hospital versus InReach-based care. METHODS: Prospective observational study of consecutive patients referred to a Victorian InReach service meeting COVID-19 testing criteria between April and October 2020 (prevaccine availability)...
August 25, 2022: Internal Medicine Journal
https://read.qxmd.com/read/35947458/phenotypic-frailty-score-predicts-perioperative-outcomes-for-geriatric-total-joint-arthroplasty
#37
JOURNAL ARTICLE
Sahir S Pervaiz, Scott J Douglas, Oliver C Sax, Austin Nabet, Ruben G Monarrez, Ethan A Remily, Thomas Novack, James Nace, Ronald E Delanois
Various assessment tools are often used to predict perioperative morbidity among patients older than 75 years who undergo total joint arthroplasty. Yet, few studies describe the use of phenotypic frailty as a predictor for outcomes. The goal of this study was to assess phenotypic frailty with the Sinai Abbreviated Geriatric Evaluation (SAGE) and compare its utility with established assessment tools used in practice. We specifically asked: (1) Can SAGE predict 30-day outcomes, including postoperative delirium? (2) Can SAGE determine the risk of prolonged hospital length of stay? (3) Is SAGE predictive for 30-day readmissions? (4) Can SAGE determine the risk of discharge to a specialized facility? Patients undergoing total hip arthroplasty and total knee arthroplasty were evaluated with the American Association of Anesthesiologists Physical Status (ASA), Charlson Comorbidity Index (CCI), 5-point Modified Frailty Score (5-FS), and SAGE...
August 10, 2022: Orthopedics
https://read.qxmd.com/read/35923592/baseline-anxiety-and-depression-and-risk-for-icu-delirium-a-prospective-cohort-study
#38
JOURNAL ARTICLE
Ting Ting Wu, Rens Kooken, Marieke Zegers, Sally Ko, O Joseph Bienvenu, John W Devlin, Mark van den Boogaard
OBJECTIVES: Anxiety and depression are common mental disorders in adults admitted to the ICU. Although depression increases postsurgical delirium and anxiety does not, their associations with ICU delirium in critically ill adults remain unclear. We evaluated the association between ICU baseline anxiety and depression and ICU delirium occurrence. DESIGN: Subgroup analysis of a prospective cohort study. SETTING: Single, 36-bed mixed ICU. PATIENTS: Nine-hundred ninety-one ICU patients admitted with or without delirium between July 2016 and February 2020; patients admitted after elective surgery or not assessed for anxiety/depression were excluded...
July 2022: Critical care explorations
https://read.qxmd.com/read/35923543/perivascular-spaces-visible-on-magnetic-resonance-imaging-predict-subsequent-delirium-in-older-patients
#39
JOURNAL ARTICLE
Quhong Song, Yanli Zhao, Taiping Lin, Jirong Yue
Background: It remains unknown whether perivascular spaces (PVS) are associated with delirium in older hospitalized patients. We aimed to determine the association between magnetic resonance imaging (MRI)-visible PVS and the risk of delirium in a cohort of older patients. Methods: We consecutively recruited older patients (≥70 years) admitted to the Geriatric Department of West China Hospital between March 2016 and July 2017, and their imaging data within one year before admission were reviewed retrospectively...
2022: Frontiers in Aging Neuroscience
https://read.qxmd.com/read/35905797/characteristics-of-geriatric-rehabilitation-inpatients-based-on-their-frailty-severity-and-change-in-frailty-severity-during-admission-resort
#40
JOURNAL ARTICLE
Alec P L Tolley, Esmee M Reijnierse, Andrea B Maier
BACKGROUND: Frailty is prevalent amongst geriatric inpatients and worsens clinical outcomes. Determinants of admission frailty and changes in frailty severity are potential targets for intervention. OBJECTIVE: To identify characteristics associated with frailty severity at admission and change in frailty severity during geriatric rehabilitation. METHODS: The observational, prospective, longitudinal inception cohort REStORing health of acutely unwell adulTs (RESORT) includes geriatric rehabilitation inpatients...
October 2022: Mechanisms of Ageing and Development
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