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https://www.readbyqxmd.com/read/28781035/evidence-based-advances-in-avian-medicine
#1
REVIEW
Noémie M Summa, David Sanchez-Migallon Guzman
This article presents relevant advances in avian medicine and surgery over the past 5 years. New information has been published to improve clinical diagnosis in avian diseases. This article also describes new pharmacokinetic studies. Advances in the understanding and treatment of common avian disorders are presented in this article, as well. Although important progress has been made over the past years, there is still much research that needs to be done regarding the etiology, pathophysiology, diagnosis, and treatment of avian diseases and evidence-based information is still sparse in the literature...
September 2017: Veterinary Clinics of North America. Exotic Animal Practice
https://www.readbyqxmd.com/read/28768863/hras-egfr-met-and-ron-are-recurrently-activated-by-provirus-insertion-in-mav-2-retrovirus-induced-liver-tumors
#2
Vladimir Pecenka, Petr Pajer, Vít Karafiat, Petra Kasparova, Jana Dudlova, Michal Dvorak
Myeloblastosis-associated virus-2 (MAV-2) is a highly tumorigenic simple avian retrovirus. Chickens infected in ovo with MAV-2 develop tumors in kidneys, lungs, and liver with a short latency of less then 8 weeks. Here we report the results of molecular analyses of MAV-2-induced liver tumors that fall into three classes: hepatic hemangiosarcomas (HHS), intrahepatic cholangiocarcinomas (ICC), and hepatocellular carcinomas (HCC). Comprehensive inverse PCR-based screening of 92 chicken liver tumors revealed that in ca 86 % of these tumors, MAV-2 provirus had integrated into one of four gene loci: HRAS, EGFR, MET, and RON Insertionally mutated genes correlated with tumor type - HRAS was hit in HHSs, MET in ICCs, RON mostly in ICCs and EGFR mostly in HCC...
August 2, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28712138/hematologic-reference-intervals-and-age-effect-in-european-strigiformes
#3
Susana Agusti Montolio, Rafael Molina López, Carolyn Cray, Santiago Lavín González, Olga Nicolás Francisco, Ignasi Marco Sánchez, Encarna Casas-Díaz, Rafaela Cuenca Valera
BACKGROUND: The clinical importance of hematologic testing in avian veterinary medicine is reflected in the increasing number of studies for the establishment of hematologic RIs of Strigiformes and other species. Age is an important physiologic factor in birds and the effect on hematology variable should be understood. OBJECTIVES: The objective of this study was to determine baseline data of hematologic variables in 5 species of Iberian Strigiformes in different age classes...
July 16, 2017: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/28695835/the-concept-of-travel-medicine-and-the-actual-situation-of-travel-related-illnesses
#4
Varol Tunalı, Nevin Turgay
Travel medicine defines all diseases and medical situations that are related to travel. Travel medicine comprises infectious diseases, traumas, altitude sickness, sun burns, embolisms, jet lag, and many more travel-related situations. With the increasing possibility and ease of travel, the number of people who have travelled internationally has exceeded 1.13 billion in 2014, and the revenues of international travel have exceeded 1.25 trillion dollars. With every passing day, international travels are shifting toward the developing countries and to more exotic regions of the world, and travelers tend to be more adventurous and daring, thereby increasing risky behaviors during travels...
June 2017: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/28445657/aquatic-bird-bornavirus-associated-disease-in-free-living-canada-geese-branta-canadensis-in-the-northeastern-usa
#5
Maureen Murray, Jianhua Guo, Ian Tizard, Samuel Jennings, H L Shivaprasad, Susan Payne, Julie C Ellis, Arnaud J Van Wettere, Kathleen M O'Brien
During the winter of 2013-14, 22 Canada geese ( Branta canadensis ) were admitted to the Wildlife Clinic at the Cummings School of Veterinary Medicine at Tufts University with nonspecific neurologic abnormalities and emaciation. Five of these geese, along with three geese that were submitted dead, were evaluated via histopathology, immunohistochemistry, and reverse transcription PCR (RT-PCR) for bornaviruses. Histopathologically, six of the eight birds had lymphoplasmacytic encephalitis. One bird, which also had encephalitis, had a dilated esophagus...
July 2017: Journal of Wildlife Diseases
https://www.readbyqxmd.com/read/28253926/exo-erythrocytic-development-of-avian-malaria-and-related-haemosporidian-parasites
#6
REVIEW
Gediminas Valkiūnas, Tatjana A Iezhova
BACKGROUND: Avian malaria parasites (Plasmodium spp.) and related haemosporidians (Haemosporida) are responsible for diseases which can be severe and even lethal in avian hosts. These parasites cause not only blood pathology, but also damage various organs due to extensive exo-erythrocytic development all over the body, which is not the case during Plasmodium infections in mammals. However, exo-erythrocytic development (tissue merogony or schizogony) remains the most poorly investigated part of life cycle in all groups of wildlife haemosporidian parasites...
March 3, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28169183/reproductive-disorders-in-commonly-kept-fowl
#7
REVIEW
Daniel Calvo Carrasco, Mikel Sabater González
Backyard poultry and other commonly kept fowl species are often kept for their ability to lay eggs. Reproductive disease is common in fowl species. Despite being classified as food-producing species, they can be considered valuable pets, and the demand for adequate veterinary care is constantly increasing. The clinician should be familiar with the different abnormalities and the potential treatment options. Fowl species have been traditionally an anatomic, physiologic, and experimental model for avian medicine; however, information about treatment options is often limited and extrapolated from other species...
May 2017: Veterinary Clinics of North America. Exotic Animal Practice
https://www.readbyqxmd.com/read/28107065/cumulative-author-indexjournal-of-avian-medicine-and-surgery-volume-30-2016
#8
(no author information available yet)
No abstract text is available yet for this article.
December 2016: Journal of Avian Medicine and Surgery
https://www.readbyqxmd.com/read/28107062/editorial-acknowledgments
#9
(no author information available yet)
We would like to acknowledge and extend our sincere gratitude to the following people for contributions of their time, expertise, and guidance as reviewers of manuscripts for the Journal of Avian Medicine and Surgery from December 2, 2015 through November 22, 2016.
December 2016: Journal of Avian Medicine and Surgery
https://www.readbyqxmd.com/read/28099573/hematological-and-morphometric-differences-of-blood-cells-from-rheas-rhea-americana-struthioniformes-rheidae-on-two-conservation-farms
#10
S S M Gallo, N B Ederli, F C R Oliveira
Today, blood tests are an indispensable tool in avian medicine. This study aimed to describe and compare hematological and morphometric data of erythrocytes, leukocytes and thrombocytes of rhea, Rhea americana. To do so, 58 rheas of both sexes on two farms, one in Cachoeiro do Itapemirim, Espírito Santo (ES), and the other in São Carlos, São Paulo (SP), were selected. Blood samples were taken and their RBC counts, PCV and Hb levels were determined and used in hematimetric index calculations. The total and differentiated leukocyte counts and the TPP and fibrinogen serum levels were also obtained...
April 2017: Brazilian Journal of Biology, Revista Brasleira de Biologia
https://www.readbyqxmd.com/read/28061784/inhibition-of-influenza-virus-via-a-sesquiterpene-fraction-isolated-from-laggera-pterodonta-by-targeting-the-nf-%C3%AE%C2%BAb-and-p38-pathways
#11
YuTao Wang, Beixian Zhou, Jingguang Lu, QiaoLian Chen, Huihui Ti, WanYi Huang, Jing Li, ZiFeng Yang, Zhihong Jiang, XinHua Wang
BACKGROUND: Influenza virus poses serious threats to human health, especially human infection with avian influenza virus. Laggera pterodonta (DC.) Benth is a medicinal plant that is widely used in Traditional Chinese Medicine, especially in Yunnan province, and has been used to treat influenza, pharyngolaryngitis, and bronchitis. However, the compound(s) responsible for the activity and their mechanisms of action against the influenza virus remain to be elucidated. METHODS: L...
January 6, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28017915/natural-recombination-in-alphaherpesviruses-insights-into-viral-evolution-through-full-genome-sequencing-and-sequence-analysis
#12
REVIEW
Carlos A Loncoman, Paola K Vaz, Mauricio Jc Coppo, Carol A Hartley, Francisco J Morera, Glenn F Browning, Joanne M Devlin
Recombination in alphaherpesviruses was first described more than sixty years ago. Since then, different techniques have been used to detect recombination in natural (field) and experimental settings. Over the last ten years, next-generation sequencing (NGS) technologies and bioinformatic analyses have greatly increased the accuracy of recombination detection, particularly in field settings, thus contributing greatly to the study of natural alphaherpesvirus recombination in both human and veterinary medicine...
December 23, 2016: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/27996363/randomized-double-blind-multi-center-phase-iii-clinical-trial-to-evaluate-the-immunogenicity-and-safety-of-mg1109-egg-based-pre-pandemic-influenza-a-h5n1-vaccine-in-healthy-adults
#13
Joon Young Song, Min Joo Choi, Ji Yun Noh, Won Suk Choi, Hee Jin Cheong, Seong-Heon Wie, Jin-Soo Lee, Gyu-Jin Woo, Sang Ho Lee, Woo Joo Kim
Considering the pandemic potential of avian influenza A/H5N1, development of an effective and well-tolerated vaccine is an essential part of pandemic preparedness plans. This phase III, randomized, double-blind study was conducted to assess the immunogenicity and safety profile of an alum-adjuvanted, whole virion, pre-pandemic influenza A/H5N1 vaccine (MG1109). Healthy individuals were randomly assigned, in a 3:1 ratio, to receive two doses of either MG1109 or placebo containing alum gel. Immunogenicity was determined by hemagglutination inhibition (HI) and microneutralization (MN) assays...
May 4, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/27988905/intestinal-lesion-in-a-dog-due-to-cryptococcus-gattii-type-vgii-and-review-of-published-cases-of-canine-gastrointestinal-cryptococcosis
#14
Daniel Paiva Barros de Abreu, Carlos Henrique Machado, Mário Tatsuo Makita, Camila Flávia Magalhães Botelho, Fernanda Gomes Oliveira, Cristiano Chaves Pessoa da Veiga, Marilena Dos Anjos Martins, Francisco de Assis Baroni
Cryptococcosis is a mycosis caused by yeasts of genus Cryptococcus, mainly the species C. neoformans and C. gattii that can affect humans and animals. These yeasts are widely distributed in the environment and are typically associated with avian droppings and decaying wood. Most infections are related to the respiratory tract, but the central nervous system and cutaneous lesions are also reported in the literature. The present report is a case of cryptococcosis in an 18-month-old unspayed female English Bulldog with the main complaint of weight loss and diarrhea...
June 2017: Mycopathologia
https://www.readbyqxmd.com/read/27781484/molecular-characterization-of-pathogenic-and-nonpathogenic-fowl-aviadenovirus-serotype-11-isolates
#15
Patrick D Slaine, James G Ackford, Andrew M Kropinski, Robert A Kozak, Peter J Krell, Éva Nagy
Fowl aviadenoviruses, many of which are of importance in veterinary medicine, are classified into 5 species. In this study, a pathogenic isolate and a nonpathogenic isolate of fowl aviadenovirus serotype 11 (FAdV-11) of species Fowl aviadenovirus D were characterized. Growth rates were analyzed for the 2 isolates, showing notable differences. The complete genomic sequences of the viruses were fully determined and were analyzed. The genomes of the 2 isolates showed 98.1% sequence identity and revealed 6 nonsynonymous mutations between the Ontario isolates...
December 2016: Canadian Journal of Microbiology
https://www.readbyqxmd.com/read/27704591/a-cell-based-high-throughput-protocol-to-screen-entry-inhibitors-of-highly-pathogenic-viruses-with-traditional-chinese-medicines
#16
Yong Yang, Han Cheng, Hui Yan, Peng-Zhan Wang, Rong Rong, Ying-Ying Zhang, Cheng-Bo Zhang, Rui-Kun Du, Li-Jun Rong
Emerging viruses such as Ebola virus (EBOV), Lassa virus (LASV), and avian influenza virus H5N1 (AIV) are global health concerns. Since there is very limited options (either vaccine or specific therapy) approved for humans against these viruses, there is an urgent need to develop prophylactic and therapeutic treatments. Previously we reported a high-throughput screening (HTS) protocol to identify entry inhibitors for three highly pathogenic viruses (EBOV, LASV, and AIV) using a human immunodeficiency virus-based pseudotyping platform which allows us to perform the screening in a BSL-2 facility...
May 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/27596377/normal-computed-tomographic-features-and-reference-values-for-the-coelomic-cavity-in-pet-parrots
#17
Irene A Veladiano, Tommaso Banzato, Luca Bellini, Alessandro Montani, Salvatore Catania, Alessandro Zotti
BACKGROUND: The increasing popularity gained by pet birds over recent decades has highlighted the role of avian medicine and surgery in the global veterinary scenario; such a need for speciality avian medical practice reflects the rising expectation for high-standard diagnostic imaging procedures. The aim of this study is to provide an atlas of matched anatomical cross-sections and contrast-enhanced CT images of the coelomic cavity in three highly diffused psittacine species. RESULTS: Contrast-enhanced computed tomographic studies of the coelomic cavity were performed in 5 blue-and-gold macaws, 4 African grey parrots and 6 monk parakeets by means of a 4-multidetector-row CT scanner...
September 5, 2016: BMC Veterinary Research
https://www.readbyqxmd.com/read/27468016/pharmacokinetics-of-ceftiofur-crystalline-free-acid-a-long-acting-cephalosporin-in-american-flamingos-phoenicopterus-ruber
#18
Jennifer J Kilburn, Sherry K Cox, Kay A Backues
Antibiotic usage is a vital component of veterinary medicine but the unique anatomy of some species can make administration difficult. The objective of this study was to determine the pharmacokinetic parameters of ceftiofur crystalline free acid (CCFA), a long-acting cephalosporin antibiotic, after parenteral administration in American flamingos ( Phoenicopterus ruber ). A dose of 10 mg/kg of CCFA was administered intramuscularly to 11 birds and blood was collected at various time points from 0 to 192 hr. Pharmacokinetic parameters for ceftiofur equivalents were determined and reached levels above minimum inhibitory concentrations of various bacterial organisms in other avian species through 96 hr in 9/11 birds...
June 2016: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/27446400/plumbagin-exhibits-an-anti-proliferative-effect-in-human-osteosarcoma-cells-by-downregulating-fhl2-and-interfering-with-wnt-%C3%AE-catenin-signalling
#19
Yuan-Liang Xue, Xiang-Qi Meng, Long-Jun Ma, Zhen Yuan
Plumbagin, a naphthoquinone constituent of Plumbago zeylanica L. (Plumbaginaceae) is widely used in traditional Chinese medicine as an antifungal, antibacterial and anti-inflammatory agent. Plumbagin is known to exhibit proapoptotic, antiangiogenic and antimetastatic effects in cancer cells. The transcriptional co-factor four and a half LIM domains 2 (FHL2) is a multifunctional adaptor protein that is involved in the regulation of gene expression, signal transduction and cell proliferation and differentiation, and also acts as a tumor suppressor or oncoprotein depending on the tissue microenvironment...
August 2016: Oncology Letters
https://www.readbyqxmd.com/read/27241023/improvement-of-in-vivo-antimicrobial-activity-of-hbcard-peptides-by-d-arginine-replacement
#20
Heng-Li Chen, Pei-Yi Su, Chiaho Shih
We previously identified a novel antimicrobial peptide with a broad spectrum bactericidal activity from human hepatitis B virus (HBV) core protein (HBc) arginine-rich domain (ARD). We compared the antimicrobial activities of HBcARD peptides from different hepadnaviruses which share similar amino acid sequences. In general, mammalian HBcARD peptides exhibited stronger antimicrobial activity than avian peptides. Using the strategy of D-amino acid substitutions, we improved the antimicrobial efficacy of human HBcARD peptide...
November 2016: Applied Microbiology and Biotechnology
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