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https://www.readbyqxmd.com/read/28526831/selection-of-a-horizontal-reference-plane-in-3d-evaluation-identifying-facial-asymmetry-and-occlusal-cant-in-orthognathic-surgery-planning
#1
Daniel Lonic, Ali Sundoro, Hsiu-Hsia Lin, Pei-Ju Lin, Lun-Jou Lo
Facial asymmetry and dental occlusal cant have been detected in two-dimensional cephalometry using different horizontal reference lines, but equivalent 3-dimensional (3D) reference planes have not been thoroughly investigated. In this study, 3D cone-beam computed tomography scans of 83 consecutive patients were evaluated using a standardized 3D frame and three horizontal reference planes, Supraorbitale (Sor), Frontozygomatic (Z), and Frankfurt horizontal (FH) for cant detection. Canting was defined as a vertical difference between left and right sides of 2 mm or more, and in at least two investigated planes...
May 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28525623/the-survey-of-tinea-capitis-and-scalp-dermatophyte-carriage-in-nursing-home-residents
#2
Chien-Yio Lin, Hsiu-Jung Lo, Ming-Gene Tu, Yu-Ming Ju, Yun-Chen Fan, Chih-Chao Lin, Ya-Ting Chiang, Yun-Liang Yang, Kai-Ting Chen, Pei-Lun Sun
Tinea capitis is a contagious dermatophyte infection of scalp and associated hairs. On the other hand, asymptomatic carriage is a status of positive dermatophyte scalp culture, but without signs or symptoms of tinea capitis, and no evidence of hair shaft invasion confirmed by direct microscopy. Tinea capitis and asymptomatic carriage mostly occur in children, but adult females are becoming another population in recent decades. In this study, we focused on the prevalence and related fungi of tinea capitis and asymptomatic carriage in elderly by the shampoo brush method, as well as the source of transmission, in 10 nursing home residents...
May 18, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/28523161/the-safety-profile-of-preoperative-administration-of-heparin-for-thromboprophylaxis-in-chinese-patients-intended-for-thoracoscopic-major-thoracic-surgery-a-pilot-randomized-controlled-study
#3
Han-Yu Deng, Chang-Lin Shi, Gang Li, Jun Luo, Zhi-Qiang Wang, Yi-Dan Lin, Lun-Xu Liu, Qing-Hua Zhou
BACKGROUND: Patients undergoing major thoracic surgery especially for cancers are at a high risk of perioperative thromboembolism. Current guidelines recommended either heparin sodium (unfractionated heparin) or low-molecular-weight heparin (LMWH) for those patients at high risk of deep vein thrombosis (DVT). However, the rational timing of starting heparin has not yet been well established, because DVT can be caused by not only surgery but also comorbidities as well as prolonged hospital stay, and thoracic surgeons always concerned about heparin-related increased risk of intra- or post-operative bleeding...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28522821/self-selecting-resistive-switching-scheme-using-tio2-nanorod-arrays
#4
Chi-Hsin Huang, Ta-Shun Chou, Jian-Shiou Huang, Shih-Ming Lin, Yu-Lun Chueh
In this study, the resistive switching scheme using TiO2 nanorod arrays synthesized by a large-scale and low-cost hydrothermal process was reported. Especially, the nonlinear I-V characteristics of TiO2 nanorod arrays with a nonlinearity of up to ~10, which suppress the leakage current less than 10(-4) Acm(-2), were demonstrated, exhibiting a self-selecting resistive switching behavior. It provides a simple pathway for integration of RRAM crossbar arrays without additional stacking of active devices. The mechanisms of the nonlinear resistive switching behaviors were discussed in detail...
May 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28522562/estrogen-and-cigarette-sidestream-smoke-particulate-matter-exhibit-er%C3%AE-dependent-tumor-promoting-effects-in-lung-adenocarcinoma-cells
#5
Lun-Cheng Kuo, Li-Chuan Cheng, Chia-Huei Lee, Chun-Ju Lin, Pei-Yu Chen, Lih-Ann Li
Estrogen and secondhand smoke are key risk factors for nonsmoking female lung cancer patients, who frequently have lung adenocarcinoma and show tumor ERα expression. We speculated that estrogen and secondhand smoke might cause harmful effects via ERα signaling. Our results showed that 17β-estradiol (E2), the primary form of endogenous estrogen, exacerbated proliferation, migration, and granzyme B resistance of lung adenocarcinoma cells in an ERα-dependent manner. Cigarette sidestream smoke particulate matter (CSSP), the major component of secondhand smoke, could activate ERα activity dose dependently in human lung adenocarcinoma cells...
May 18, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/28521677/molluscum-contagiosum-an-update
#6
Alexander Kc Leung, Benjamin Barankin, Kam Lun Hon
BACKGROUND: Molluscum contagiosum is a viral cutaneous infection in childhood that occurs worldwide. Physicians should familiarize themselves with this common condition. OBJECTIVE: To review in depth the epidemiology, pathophysiology, clinical manifestations, complications and, in particular, treatment of molluscum contagiosum. METHODS: A PubMed search was completed in Clinical Queries using the key term "molluscum contagiosum". Patents were searched using the key term "molluscum contagiosum" from www...
May 17, 2017: Recent Patents on Inflammation & Allergy Drug Discovery
https://www.readbyqxmd.com/read/28521225/recovery-of-gold-from-industrial-wastewater-by-extracellular-proteins-obtained-from-a-thermophilic-bacterium-tepidimonas-fonticaldi-at-a2
#7
Yin-Lung Han, Jen-Hao Wu, Chieh-Lun Cheng, Dillirani Nagarajan, Ching-Ray Lee, Yi-Heng Li, Yung-Chung Lo, Jo-Shu Chang
Biosorption has emerged as a promising alternative approach for treating wastewater with dilute metal contents in a green and cost effective way. In this study, extracellular proteins of an isolated thermophilic bacterium (Tepidimonas fonticaldi AT-A2) were used as biosorbent to recover precious metal (i.e., Au) from wastewater. The Au (III) adsorption capacity on the T. fonticaldi AT-A2 proteins was the highest when the pH was set at about 4.0-5.0. The adsorption capacity increased with increasing temperature from 15 to 70°C...
May 10, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28516459/pp2a-deactivation-is-a-common-event-in-oral-cancer-and-reactivation-by-fty720-shows-promising-therapeutic-potential
#8
Bharath Kumar Velmurugan, Chien-Hung Lee, Shang-Lun Chiang, Chun-Hung Hua, Mei-Chung Chen, Shu-Hui Lin, Kun-Tu Yeh, Ying-Chin Ko
Protein phosphatase 2A (PP2A) is a tumor suppressor gene, that has been frequently deactivated in many types of cancer. However its molecular and clinical relevance in oral squamous cell carcinoma (OSCC) remain unclear. Here we show that, PP2A deactivation is a common event in oral cancer cells and hyperphosphorylation in its tyrosine-307 (Y307) residue contributes to PP2A deactivation. PP2A restoration by FTY720 treatment reduced cell growth and decreased GSK-3β phosphorylation without significantly altering other PP2A targets...
May 18, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28513666/high-performance-solution-processable-tetrathienoacene-ttar-based-small-molecules-for-organic-field-effect-transistors-ofets
#9
Sureshraju Vegiraju, Deng-Yi Huang, Pragya Priyanka, Yo-Shan Li, Xian-Lun Luo, Shao-Huan Hong, Jen-Shyang Ni, Shih-Huang Tung, Chien-Lung Wang, Wei-Chieh Lien, Shueh Lin Yau, Cheng-Liang Liu, Ming-Chou Chen
Three new organic semiconductors with alkyl chain-substituted tetrathienoacene (TTAR) as the central core and both ends capped with thiophene (DT-TTAR), thienothiophene (DTT-TTAR) and dithienothiophene (DDTT-TTAR) have been synthesized and characterized for organic field effect transistor (OFET) applications. A hole mobility of 0.81 cm(2) V(-1) s(-1) was achieved for the DDTT-TTAR film, which represents the highest mobility yet found for a solution-processable p-type TTAR-based small molecular semiconductors...
May 17, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28511974/risk-factor-analysis-for-meralgia-paresthetica-a-hospital-based-study-in-taiwan
#10
Wei-Chieh Weng, Yi-Chia Wei, Wen-Yi Huang, Yu-Yi Chien, Tsung-I Peng, Chia-Lun Wu
Recognizing the cause is essential for the management of meralgia paresthetica (MP), also known as lateral femoral cutaneous neuropathy. The aim of this study was to investigate the etiologies of MP and their influence on each other. This retrospective study enrolled referral patients with electromyographic studies who fulfilled the clinical and electrodiagnostic criteria of MP from January 2003 to December 2013. Data including age, gender, body weight, body height, occupation, and relevant medical history were collected...
May 13, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28509919/resistive-switching-of-sn-doped-in2o3-hfo2-core-shell-nanowire-geometry-architecture-engineering-for-nonvolatile-memory
#11
Chi-Hsin Huang, Wen-Chih Chang, Jian-Shiou Huang, Shih-Ming Lin, Yu-Lun Chueh
Core-shell NWs offer an innovative approach to achieve nanoscale metal-insulator-metal (MIM) heterostructures along the wire radial direction, realizing three-dimensional geometry architecture rather than planar type thin film devices. This work demonstrated the tunable resistive switching characteristics of ITO/HfO2 core-shell nanowires with controllable shell thicknesses by the atomic layer deposition (ALD) process for the first time. Compared to planar HfO2 thin film device configuration, ITO/HfO2 core-shell nanowire shows a prominent resistive memory behavior, including lower power consumption with a smaller SET voltage of ∼0...
May 16, 2017: Nanoscale
https://www.readbyqxmd.com/read/28508542/dynamic-self-assembly-of-homogenous-microcyclic-structures-controlled-by-a-silver-coated-nanopore
#12
Rui Gao, Yao Lin, Yi-Lun Ying, Xiao-Yuan Liu, Xin Shi, Yong-Xu Hu, Yi-Tao Long, He Tian
The self-assembly of nanoparticles is a challenging process for organizing precise structures with complicated and ingenious structures. In the past decades, a simple, high-efficiency, and reproducible self-assembly method from nanoscale to microscale has been pursued because of the promising and extensive application prospects in bioanalysis, catalysis, photonics, and energy storage. However, microscale self-assembly still faces big challenges including improving the stability and homogeneity as well as pursuing new assembly methods and templates for the uniform self-assembly...
May 16, 2017: Small
https://www.readbyqxmd.com/read/28507703/advanced-electroanalytical-chemistry-at-nanoelectrodes
#13
Yi-Lun Ying, Zhifeng Ding, Dongping Zhan, Yi-Tao Long
Nanoelectrodes, with dimensions below 100 nm, have the advantages of high sensitivity and high spatial resolution. These electrodes have attracted increasing attention in various fields such as single cell analysis, single-molecule detection, single particle characterization and high-resolution imaging. The rapid growth of novel nanoelectrodes and nanoelectrochemical methods brings enormous new opportunities in the field. In this perspective, we discuss the challenges, advances, and opportunities for nanoelectrode fabrication, real-time characterizations and high-performance electrochemical instrumentation...
May 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28504682/testing-for-differential-abundance-in-mass-cytometry-data
#14
Aaron T L Lun, Arianne C Richard, John C Marioni
When comparing biological conditions using mass cytometry data, a key challenge is to identify cellular populations that change in abundance. Here, we present a computational strategy for detecting 'differentially abundant' populations by assigning cells to hyperspheres, testing for significant differences between conditions and controlling the spatial false discovery rate. Our method (http://bioconductor.org/packages/cydar) outperforms other approaches in simulations and finds novel patterns of differential abundance in real data...
May 15, 2017: Nature Methods
https://www.readbyqxmd.com/read/28504254/neural-circuits-for-long-term-water-reward-memory-processing-in-thirsty-drosophila
#15
Wei-Huan Shyu, Tai-Hsiang Chiu, Meng-Hsuan Chiang, Yu-Chin Cheng, Ya-Lun Tsai, Tsai-Feng Fu, Tony Wu, Chia-Lin Wu
The intake of water is important for the survival of all animals and drinking water can be used as a reward in thirsty animals. Here we found that thirsty Drosophila melanogaster can associate drinking water with an odour to form a protein-synthesis-dependent water-reward long-term memory (LTM). Furthermore, we found that the reinforcement of LTM requires water-responsive dopaminergic neurons projecting to the restricted region of mushroom body (MB) β' lobe, which are different from the neurons required for the reinforcement of learning and short-term memory (STM)...
May 15, 2017: Nature Communications
https://www.readbyqxmd.com/read/28501653/incorporating-wind-availability-into-land-use-regression-modelling-of-air-quality-in-mountainous-high-density-urban-environment
#16
Yuan Shi, Kevin Ka-Lun Lau, Edward Ng
Urban air quality serves as an important function of the quality of urban life. Land use regression (LUR) modelling of air quality is essential for conducting health impacts assessment but more challenging in mountainous high-density urban scenario due to the complexities of the urban environment. In this study, a total of 21 LUR models are developed for seven kinds of air pollutants (gaseous air pollutants CO, NO2, NOx, O3, SO2 and particulate air pollutants PM2.5, PM10) with reference to three different time periods (summertime, wintertime and annual average of 5-year long-term hourly monitoring data from local air quality monitoring network) in Hong Kong...
May 11, 2017: Environmental Research
https://www.readbyqxmd.com/read/28501324/using-a-new-plateau-hyperbaric-chamber-to-alleviate-high-altitude-hypoxia-rabbit-and-human-studies
#17
Liang Sun, Meng-Jiang Ding, Tian-Cai Cai, Hao-Jun Fan, Hong-Mei Gao, Jian-Peng Zhang
OBJECTIVES: To validate the effects of the new plateau hyperbaric chamber on alleviating high altitude hypoxia on Mount Kun Lun. METHODS: A prospective, controlled study of rabbits and adult volunteers was conducted at altitudes of 355, 2880 and 4532m. We obtained arterial blood samples from rabbits and volunteers before and after hyperbaric treatment. The respiratory rate, heart rate, and blood pressure (BP) of adult volunteers were monitored during hyperbaric treatment...
April 19, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28498854/single-trait-and-multi-trait-genome-wide-association-analyses-identify-novel-loci-for-blood-pressure-in-african-ancestry-populations
#18
Jingjing Liang, Thu H Le, Digna R Velez Edwards, Bamidele O Tayo, Kyle J Gaulton, Jennifer A Smith, Yingchang Lu, Richard A Jensen, Guanjie Chen, Lisa R Yanek, Karen Schwander, Salman M Tajuddin, Tamar Sofer, Wonji Kim, James Kayima, Colin A McKenzie, Ervin Fox, Michael A Nalls, J Hunter Young, Yan V Sun, Jacqueline M Lane, Sylvia Cechova, Jie Zhou, Hua Tang, Myriam Fornage, Solomon K Musani, Heming Wang, Juyoung Lee, Adebowale Adeyemo, Albert W Dreisbach, Terrence Forrester, Pei-Lun Chu, Anne Cappola, Michele K Evans, Alanna C Morrison, Lisa W Martin, Kerri L Wiggins, Qin Hui, Wei Zhao, Rebecca D Jackson, Erin B Ware, Jessica D Faul, Alex P Reiner, Michael Bray, Joshua C Denny, Thomas H Mosley, Walter Palmas, Xiuqing Guo, George J Papanicolaou, Alan D Penman, Joseph F Polak, Kenneth Rice, Ken D Taylor, Eric Boerwinkle, Erwin P Bottinger, Kiang Liu, Neil Risch, Steven C Hunt, Charles Kooperberg, Alan B Zonderman, Cathy C Laurie, Diane M Becker, Jianwen Cai, Ruth J F Loos, Bruce M Psaty, David R Weir, Sharon L R Kardia, Donna K Arnett, Sungho Won, Todd L Edwards, Susan Redline, Richard S Cooper, D C Rao, Jerome I Rotter, Charles Rotimi, Daniel Levy, Aravinda Chakravarti, Xiaofeng Zhu, Nora Franceschini
Hypertension is a leading cause of global disease, mortality, and disability. While individuals of African descent suffer a disproportionate burden of hypertension and its complications, they have been underrepresented in genetic studies. To identify novel susceptibility loci for blood pressure and hypertension in people of African ancestry, we performed both single and multiple-trait genome-wide association analyses. We analyzed 21 genome-wide association studies comprised of 31,968 individuals of African ancestry, and validated our results with additional 54,395 individuals from multi-ethnic studies...
May 12, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28498313/identifying-the-genes-regulated-by-atwrky6-using-comparative-transcript-and-proteomic-analysis-under-phosphorus-deficiency
#19
Li-Qin Li, Lu-Ping Huang, Gang Pan, Lun Liu, Xi-Yao Wang, Li-Ming Lu
Phosphorus (P) is an important mineral nutrient for plant growth and development. Overexpressing AtWRKY6 (35S:WRKY6-9) was more sensitive and wrky6 (wrky6-1) was more resistant under low Pi conditions. To better understand the function of AtWRKY6 under low phosphate stress conditions, we applied two-dimensional gel electrophoresis (2-DE) to analyse differentially expressed proteins in the shoots and roots between wild type, 35S:WRKY6-9 and wrky6-1 after phosphorus deficiency treatment for three days. The results showed 88 differentially abundant protein spots, which were identified between the shoots and roots of 35S:WRKY6-9 and wrky6-1 plants...
May 12, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28498239/the-validity-of-using-human-squamous-cell-carcinoma-associated-antigen-and-cytokeratin-19-fragment-antigen-21-1-to-predict-postoperative-adjuvant-radiotherapy-for-nonbulky-early-stage-squamous-cell-carcinoma-of-the-cervix
#20
Chan-Zhen Liu, Hao-Xia Zeng, Jing-Jing Zhao, Yan Rong, Zhe-Lun Mo, Li A Li, Jie-Qing Zhang
OBJECTIVE: There are no generally accepted biomarkers for the optimal selection of radiotherapy-based or surgical-based treatment options for nonbulky early-stage squamous cell carcinoma of the cervix (IA1-IB1 and IIA1). The objective of this study was to assess the value of human squamous cell carcinoma-associated antigen (SCC-Ag) and cytokeratin 19 fragment antigen 21-1 (CYFRA21-1) in evaluation of patients with nonbulky early-stage squamous cell carcinoma of the cervix to determine if radiotherapy is warranted after radical surgery...
June 2017: International Journal of Gynecological Cancer
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