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Mohammad Abd Alkhalik Basha, Mohamad Zakarya AlAzzazy, Ayman F Ahmed, Hala Y Yousef, Samar Mohamad Shehata, Dena Abd El Aziz El Sammak, Talaat Fathy, Ahmed Ali Obaya, Eman H Abdelbary
OBJECTIVE: To compare diagnostic performance and agreement between CT, MRI and combined CT/MRI in reference to LI-RADS classification system to categorize hepatic observations detected in hepatic patients during screening ultrasound. METHODS: 240 patients with 296 liver observations detected during ultrasound surveillance underwent hepatic CT and MRI examinations, histopathology, and clinical and radiological follow-up. Using LI-RADS v2014, six radiologists evaluated the observations independently and assigned a LI-RADS category to each observation using CT, MRI and combined CT/MRI...
January 24, 2018: European Radiology
Chen-Pei Ho, Jih-I Yeh, Shu-Hui Wen, Tony Jer-Fu Lee
The aim of this study was to explore the associations among the medication regimen complexity index (MRCI), medical specialty, and medication possession ratio (MPR) in newly diagnosed hypertensive patients.Data from 19,859 newly diagnosed hypertensive patients were collected from 2,000,000 random samples of the National Health Insurance Research Database in Taiwan. All study participants were followed for 1 year after the first diagnosis of hypertension. MPR was defined as total days of antihypertensive drugs supplied/365 days...
November 2017: Medicine (Baltimore)
Ravi Salgia, John R Stille, R Waide Weaver, Michael McCleod, Oday Hamid, John Polzer, Stephanie Roberson, Amy Flynt, David R Spigel
OBJECTIVES: This multicenter, open-label, randomized phase II study evaluated the efficacy and safety of LY2510924 (LY) added to first-line standard of care (SOC) chemotherapy for extensive-disease small cell lung cancer (ED-SCLC) and explored the predictive value of C-X-C motif receptor 4 (CXCR4) tumor response. MATERIALS AND METHODS: Patients with treatment-naïve ED-SCLC were randomized (1:1) to receive up to six 21-day cycles of carboplatin/etoposide alone (SOC) or in combination with 20mg LY2510924 administered subcutaneously on days 1-7 of each cycle (LY+SOC)...
March 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
Jacob T Gibby, Dennis K Njeru, Steve T Cvetko, Eric L Heiny, Andrew R Creer, Wendell A Gibby
OBJECTIVE: We correlate and evaluate the accuracy of accepted anthropometric methods of percent body fat (%BF) quantification, namely, hydrostatic weighing (HW) and air displacement plethysmography (ADP), to 2 automatic adipose tissue quantification methods using computed tomography (CT). METHODS: Twenty volunteer subjects (14 men, 6 women) received head-to-toe CT scans. Hydrostatic weighing and ADP were obtained from 17 and 12 subjects, respectively. The CT data underwent conversion using 2 separate algorithms, namely, the Schneider method and the Beam method, to convert Hounsfield units to their respective tissue densities...
March 2017: Journal of Computer Assisted Tomography
Marius Henriksen, Julie B Hansen, Louise Klokker, Henning Bliddal, Robin Christensen
AIM: Evidence of comparative effectiveness of different treatment approaches is important for clinical decision-making, yet absent for most recommended treatments of knee osteoarthritis pain. The objective of this study was to estimate the comparative effectiveness of exercise versus orally administered analgesics for pain in patients with knee osteoarthritis. METHODS: The Cochrane Database of systematic reviews was searched for meta-analyses of randomized controlled studies comparing exercise or analgesics with a control group (placebo or usual care) and with pain as an outcome...
July 2016: Journal of Comparative Effectiveness Research
Wasim Ibrahim, Imrul Mosaddek Ahmed, Xianhong Chen, Fangbin Cao, Shuijin Zhu, Feibo Wu
Combined stress of salinity and heavy metal is a serious problem for crop production; however, physiological mechanisms of tolerance to such condition remain elusive in cotton. Here, we used two cotton genotypes differing in salt tolerance, to understand their response to salinity (NaCl) and cadmium (Cd) either alone or in combination (Cd + Na) via hydroponics. Results showed that salinity and/or Cd drastically reduced plant growth, chlorophyll content and photosynthesis, with greater effect observed in Zhongmian 41 (sensitive) than Zhong 9806 (tolerant)...
December 2015: Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine
Chang-Liang Jing, Xiao-Fang Dong, Jian-Ming Tong
Ultrasonic-assisted extraction (UAE) was used to extract flavonoid-enriched antioxidants from alfalfa aerial part. Response surface methodology (RSM), based on a four-factor, five-level central composite design (CCD), was employed to obtain the optimal extraction parameters, in which the flavonoid content was maximum and the antioxidant activity of the extracts was strongest. Radical scavenging capacity of the extracts, which represents the amounts of antioxidants in alfalfa, was determined by using 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulphonicacid) (ABTS) and 2,2'-diphenyl-1-picrylhydrazyl (DPPH) methods...
2015: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
H Zou, Y Zhang, J Tong, Z Liu
BACKGROUND: The diagnostic accuracy of multidetector computed tomography (MDCT) in the detection of left atrial/left atrial appendage (LA/LAA) thrombus had been tested in many studies; however, the results are controversial. AIM: The aim of the present study was to evaluate synthetically the diagnostic accuracy of MDCT in LA/LAA thrombus. METHODS: PubMed and Embase were searched for published prospective studies which compared computed tomography with transoesophageal echocardiography (TEE) in detecting LA/LAA thrombus prior to March 2014...
October 2015: Internal Medicine Journal
Tristram Chivers, Jamie S Ritch
While exploring the chemistry of tellurium-containing dichalcogenidoimidodiphosphinate ligands, the first all-tellurium member of a series of related square-planar E(II)(E')4 complexes (E and E' are group 16 elements), namely bis(P,P,P',P'-tetraphenylditelluridoimidodiphosphinato-κ(2)Te,Te')tellurium(II) (systematic name: 2,2,4,4,8,8,10,10-octaphenyl-1λ(3),5,6λ(4),7λ(3),11-pentatellura-3,9-diaza-2λ(5),4λ(5),8λ(5),10λ(5)-tetraphosphaspiro[5.5]undeca-1,3,7,9-tetraene), C48H40N2P4Te5, was obtained unexpectedly...
May 2015: Acta Crystallographica. Section C, Structural Chemistry
Danja Sarink, Lee Nedkoff, Tom Briffa, Jonathan E Shaw, Dianna J Magliano, Christopher Stevenson, Haider Mannan, Matthew Knuiman, Anna Peeters
BACKGROUND: For decades, the incidence and mortality of cardiovascular diseases (CVDs) have declined. More recently, we have seen a halting in these declines, especially at younger ages. It is difficult to predict how these changing trends will impact CVD prevalence. We aimed to predict future prevalence of CVDs in Western Australian adults from 2005-2045 based on current incidence and mortality probabilities, population growth and ageing. METHODS AND RESULTS: Multi-state life table models were developed using 2005-2009 age- and sex-specific incidence and mortality probabilities from the Western Australian Data Linkage System...
January 2016: European Journal of Preventive Cardiology
Aggrey S Semeere, Isaac Lwanga, Joseph Sempa, Sujal Parikh, Noeline Nakasujja, Robert Cumming, Andrew Kambugu, Harriet Mayanja-Kizza
BACKGROUND: We describe older (>50 years) HIV-infected adults after antiretroviral therapy (ART) initiation, evaluating immunological recovery by age category, considering individual trajectories based on the pretreatment CD4. We also describe mortality on ART and its risk factors by age category including the contribution of poor immunological recovery at a large urban clinic in Kampala, Uganda. METHODS: We performed a cohort analysis of adult (>18 years) HIV-infected patients who initiated ART between January 1, 2004 and January 3, 2012...
December 1, 2014: Journal of Acquired Immune Deficiency Syndromes: JAIDS
Janez Pavčič, Zlatko Matjačić, Andrej Olenšek
BACKGROUND: After neurological injury, gait rehabilitation typically focuses on task oriented training with many repetitions of a particular movement. Modern rehabilitation devices, including treadmills, augment gait rehabilitation. However, they typically provide gait training only in the forward direction of walking, hence the mechanisms associated with changing direction during turning are not practiced. A regular treadmill extended with the addition of rotation around the vertical axis is a simple device that may enable the practice of turning during walking...
2014: Journal of Neuroengineering and Rehabilitation
Yasunori Miyazaki, Kaoru Miyawaki, Tomonobu Uchino, Yoshiyuki Kagawa
In the dispensing process, powdered medicines are often blended with diluents or different kinds of powder. With blending, the mass percent of the medicine in the mixture is unknown until the active pharmaceutical ingredient is determined with techniques such as spectroscopy and chromatography. However, pharmacists need to confirm the exact blending ratio of the dispensing mixture in pharmacies. We aimed to develop a precise and concise method to measure the mass percent of powdered medicine mixtures without an expensive analytical apparatus...
2014: Chemical & Pharmaceutical Bulletin
Jing Liu, An Yang, Zao Fang, Yu Tan, Jian Sun
UNLABELLED: PURPOUSE: To evaluate the three-dimensional relationship between the incisive papilla and maxillary anterior teeth. METHODS: One hundred maxillary dentition models were selected. They were divided into two groups according to age (20-40 years, 40-70 years) and gender (male,female). The point cloud data of the models were obtained by three-dimensional scanning, and the three-dimensional models were reconstructed. Reference plane, reference points on the three-dimensional models were projected by using image processing software...
April 2013: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
Brian M Alexander, Meihua Wang, W K Alfred Yung, Howard A Fine, Bernadine A Donahue, Ivo W Tremont, Ray S Richards, Kevin J Kerlin, Alan C Hartford, Walter J Curran, Minesh P Mehta
The Radiation Therapy Oncology Group (RTOG) initiated the single-arm, phase II study 9806 to determine the safety and efficacy of daily thalidomide with radiation therapy in patients with newly diagnosed glioblastoma. Patients were treated with thalidomide (200 mg daily) from day one of radiation therapy, increasing by 100-200 to 1,200 mg every 1-2 weeks until tumor progression or unacceptable toxicity. The median survival time (MST) of all 89 evaluable patients was 10 months. When compared with the historical database stratified by recursive partitioning analysis (RPA) class, this end point was not different [hazard ratio (HR) = 1...
January 2013: Journal of Neuro-oncology
K Latimer, P Wilson, J Kemp, L Thompson, F Sim, C Gillberg, C Puckering, H Minnis
Disruptive behaviour disorders (DBDs), including attention-deficit/hyperactivity disorder (ADHD), oppositional defiant disorder (ODD) and conduct disorder (CD) are chronic disorders with significant overlap in aetiology and presentation. An integrative examination of environmental risk factors is lacking. Six literature searches of web-based bibliographic databases were completed to identify literature on DBDs in general and five disorders in particular: CD, ODD, ADHD, deficits of attention, motor control and perception, and reactive attachment disorder...
September 2012: Child: Care, Health and Development
Fezile S W Potwana, Bongakonke E Shandu, Werner E Van Zyl
The title compound, [Zn(C(7)H(4)N(2)O(3)S)(2)(C(2)H(6)OS)(2)], is a neutral four-coordinate complex with a tetra-hedral geometry. The metal atom is surrounded by the two dimethyl sulfoxide (DMSO) ligands, each coordinating through the O atom, and two anionic saccharinate (1,1,3-trioxo-2,3-dihydro-1λ(6),2-benzo-thia-zol-2-ide) ligands coordinating through the N atom. The tetra-hedral geometry is slightly distorted as is evident from the N-Zn-N bond angle of 113.85 (6)°, the O-Zn-O bond angle of 98.92 (6)° and O-Zn-N bond angles of 116...
December 1, 2011: Acta Crystallographica. Section E, Structure Reports Online
Fabio F Pasqualotto, Daniela P A F Braga, Rita C S Figueira, Amanda S Setti, Assumpto Iaconelli, Edson Borges
There are many studies in the literature suggesting an acquired, apparently progressive infertility due to varicocele. In fact, varicocelectomy has become the most commonly performed male infertility surgery. Assisted reproductive technologies such as intracytoplasmic sperm injection (ICSI) are also important for couples with male factor infertility associated with varicocele. Therefore, the aim of this study was to evaluate the effect of varicocelectomy on sperm quality and pregnancy rate with ICSI. Data were analyzed from 248 patients who had varicocele or underwent a previous varicocelectomy and were treated with ICSI between 2000 and 2008...
March 2012: Journal of Andrology
Rong Fan, Qiu-Ping Zhou, Guo-Fang Zhang, Mei-Yu Cai, Ping Li, Li-Hua Gan, Feng-Qi Zhao, Ji-Zhen Li, Xue-Zhong Fan, Seik Weng Ng
Nine metal compounds of Mn(II), Zn(II) and Cd(II) derived from dinitropyridone ligands (3,5-dinitro-pyrid-2-one, 2HDNP; 3,5-dinitropyrid-4-one, 4HDNP and 3,5-dinitropyrid-4-one-N- hydroxide, 4HDNPO) were characterized by elemental analysis, FT-IR and partly by TG-DSC. Three of which were further structurally characterized by X-ray single-crystal diffraction analysis. The structures of the three compounds, Mn(4DNP)(2)(H(2)O)(4), 4, Zn(4DNPO)(2)(H(2)O)(4), 8, and Cd(4DNPO)(2)(H(2)O)(4), 9, crystallize in the monoclinic space group P2(1)/n and Z = 2, with a = 8...
September 28, 2009: Journal of Chemical Crystallography
Leire Palencia, Laura Valverde, Alejandra Alvarez, Laura M Cainé, Sergio Cardoso, Miguel A Alfonso-Sánchez, M Fátima Pinheiro, Marian M de Pancorbo
The state of Santa Catarina (Brazil) is known to have represented a cultural crossroads in South America due to several historic migrations mainly from Europe and Africa. We set out to scrutinize whether the genetic imprint of these migrations could be traced through analysis of the matrilineal gene pool of the Catarinenses. The entire control region of the mitochondrial DNA was studied in 80 healthy and maternally unrelated individuals. The analysis of haplogroup distribution revealed that this population is extremely heterogeneous, showing the coexistence of matrilineal lineages with three different phylogeographic origins...
July 2010: International Journal of Legal Medicine
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