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https://www.readbyqxmd.com/read/28453427/visioncite-a-vision-science-related-database
#1
Karen S Lamson, Elizabeth G Hinton
VisionCite is a database dedicated to the visual sciences. This paid subscription database provides bibliographic information for optometry and ophthalmology-related resources and is maintained by the Illinois College of Optometry (ICO) Library. A sample search is provided, highlighting different features of the newly redesigned database.
April 2017: Medical Reference Services Quarterly
https://www.readbyqxmd.com/read/28453426/taking-chances-a-new-librarian-and-curriculum-redesign
#2
Iris Kovar-Gough
As technology becomes ubiquitous in designing and delivering medical school curricula, health sciences librarians can embrace emerging opportunities for participation in curriculum design. A new medical librarian at Michigan State University Libraries engaged her user base outside of established duties, learned new skills, and challenged preconceived notions about librarians' roles. In the process, she became a partner in copyright education, amended license agreements for enhanced curricular multimedia use, and facilitated curriculum mapping through taxonomy building...
April 2017: Medical Reference Services Quarterly
https://www.readbyqxmd.com/read/28443273/utilizing-the-plan-do-study-act-framework-to-explore-the-process-of-curricular-assessment-and-redesign-in-a-physical-therapy-education-program-in-suriname
#3
Jennifer Gail Audette, Se-Sergio Baldew, Tony C M S Chang, Jessica de Vries, Nancy Ho A Tham, Johanna Janssen, Andre Vyt
PURPOSE: To describe how a multinational team worked together to transition a physical therapy (PT) educational program in Paramaribo, Suriname, from a Bachelor level to a Master of Science in Physical Therapy (MSPT) level. The team was made up of PT faculty from Anton De Kom Universiteit van Suriname (AdeKUS), the Flemish Interuniversity Council University Development Cooperation (VLIR-UOS) leadership, and Health Volunteers Overseas volunteers. In this case study, the process for curricular assessment, redesign, and upgrade is described retrospectively using a Plan, Do, Study, Act (PDSA) framework...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28442114/nested-multiplex-pcr-for-identification-and-detection-of-human-plasmodium-species-including-plasmodium-knowlesi
#4
Maria Miguel-Oteo, Adela I Jiram, Thuy H Ta-Tang, Marta Lanza, Shamilah Hisam, José M Rubio
OBJECTIVE: To develop a new technique for diagnosis of Plasmodium knowlesi and at the same time to be able to discriminate among the diverse species of Plasmodium causing human malaria. METHODS: In this study the nested multiplex malaria PCR was redesigned, targeting the 18S rRNA gene, to identify the fifth human Plasmodium species, Plasmodium knowlesi, together with the other human Plasmodium (Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale and Plasmodium malariae) by amplified fragment size using only two amplification processes and including an internal reaction control to avoid false negatives...
March 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28439835/the-uea-small-rna-workbench-a-suite-of-computational-tools-for-small-rna-analysis
#5
Irina Mohorianu, Matthew Benedict Stocks, Christopher Steven Applegate, Leighton Folkes, Vincent Moulton
RNA silencing (RNA interference, RNAi) is a complex, highly conserved mechanism mediated by short, typically 20-24 nt in length, noncoding RNAs known as small RNAs (sRNAs). They act as guides for the sequence-specific transcriptional and posttranscriptional regulation of target mRNAs and play a key role in the fine-tuning of biological processes such as growth, response to stresses, or defense mechanism.High-throughput sequencing (HTS) technologies are employed to capture the expression levels of sRNA populations...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28438161/refolddb-a-new-and-sustainable-gateway-to-experimental-protocols-for-protein-refolding
#6
Hisashi Mizutani, Hideaki Sugawara, Ashley M Buckle, Takeshi Sangawa, Ken-Ichi Miyazono, Jun Ohtsuka, Koji Nagata, Tomoki Shojima, Shohei Nosaki, Yuqun Xu, Delong Wang, Xiao Hu, Masaru Tanokura, Kei Yura
BACKGROUND: More than 7000 papers related to "protein refolding" have been published to date, with approximately 300 reports each year during the last decade. Whilst some of these papers provide experimental protocols for protein refolding, a survey in the structural life science communities showed a necessity for a comprehensive database for refolding techniques. We therefore have developed a new resource - "REFOLDdb" that collects refolding techniques into a single, searchable repository to help researchers develop refolding protocols for proteins of interest...
April 24, 2017: BMC Structural Biology
https://www.readbyqxmd.com/read/28435416/challenges-in-achieving-collaboration-in-clinical-practice-the-case-of-norwegian-health-care
#7
Sissel Steihaug, Anne-Kari Johannessen, Marian Ådnanes, Bård Paulsen, Russell Mannion
INTRODUCTION: This article summarizes and synthesizes the findings of four separate but inter-linked empirical projects which explored challenges of collaboration in the Norwegian health system from the perspectives of providers and patients. The results of the four projects are summarised in eight articles. METHODS: The eight articles constituted our empirical material. Meta-ethnography was used as a method to integrate, translate, and synthesize the themes and concepts contained in the articles in order to understand how challenges related to collaboration impact on clinical work...
July 18, 2016: International Journal of Integrated Care
https://www.readbyqxmd.com/read/28434090/a-best-practice-position-statement-on-the-role-of-the-nephrologist-in-the-prevention-and-follow-up-of-preeclampsia-the-italian-study-group-on-kidney-and-pregnancy
#8
Giorgina Barbara Piccoli, Gianfranca Cabiddu, Santina Castellino, Giuseppe Gernone, Domenico Santoro, Gabriella Moroni, Donatella Spotti, Franca Giacchino, Rossella Attini, Monica Limardo, Stefania Maxia, Antioco Fois, Linda Gammaro, Tullia Todros
Preeclampsia (PE) is a protean syndrome causing a transitory kidney disease, characterised by hypertension and proteinuria, ultimately reversible after delivery. Its prevalence is variously estimated, from 3 to 5% to 10% if all the related disorders, including also pregnancy-induced hypertension (PIH) and HELLP syndrome (haemolysis, increase in liver enzyme, low platelets) are included. Both nephrologists and obstetricians are involved in the management of the disease, according to different protocols, and the clinical management, as well as the role for each specialty, differs worldwide...
April 22, 2017: Journal of Nephrology
https://www.readbyqxmd.com/read/28432628/design-of-water-quality-monitoring-networks-with-two-information-scenarios-in-tropical-andean-basins
#9
Juan Carlos Bastidas, Jorge Julián Vélez, Jeannette Zambrano, Adela Londoño
Design and redesign of water quality monitoring networks were evaluated for two similarly sized watersheds in the tropical Andes via optimization techniques using geographic information system technology (GIS) and a matter-element analysis of 5-day biological oxygen demand (BOD5) and total suspended solids (TSS). This resulted in a flexible, objectively based design for a 1128-km(2) watershed without prior water quality data (La Miel River), and a network redesign of a 1052-km(2) watershed with historical water quality monitoring (Chinchiná River)...
April 21, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28430956/achieving-high-reliability-in-histology-%C3%A2-an-improvement-series-to-reduce-errors
#10
Yael K Heher, Yigu Chen, Sergey Pyatibrat, Edward Yoon, Jeffrey D Goldsmith, Kenneth E Sands
Objectives: Despite sweeping medical advances in other fields, histology processes have by and large remained constant over the past 175 years. Patient label identification errors are a known liability in the laboratory and can be devastating, resulting in incorrect diagnoses and inappropriate treatment. The objective of this study was to identify vulnerable steps in the histology workflow and reduce the frequency of labeling errors (LEs). Methods: In this 36-month study period, a numerical step key (SK) was developed to capture LEs...
November 1, 2016: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/28429886/patients-experiences-of-consultations-with-physician-associates-in-primary-care-in-england-a-qualitative-study
#11
Mary Halter, Vari M Drennan, Louise M Joly, Jonathan Gabe, Heather Gage, Simon de Lusignan
BACKGROUND: Physician associates are new to English general practice and set to expand in numbers. OBJECTIVE: To investigate the patients' perspective on consulting with physician associates in general practice. DESIGN: A qualitative study, using semi-structured interviews, with thematic analysis. SETTING AND PARTICIPANTS: Thirty volunteer patients of 430 who had consulted physician associates for a same-day appointment and had returned a satisfaction survey, in six general practices employing physician associates in England...
April 21, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/28424538/metal-complexes-in-cancer-therapy-an-update-from-drug-design-perspective
#12
REVIEW
Umar Ndagi, Ndumiso Mhlongo, Mahmoud E Soliman
In the past, metal-based compounds were widely used in the treatment of disease conditions, but the lack of clear distinction between the therapeutic and toxic doses was a major challenge. With the discovery of cisplatin by Barnett Rosenberg in 1960, a milestone in the history of metal-based compounds used in the treatment of cancers was witnessed. This forms the foundation for the modern era of the metal-based anticancer drugs. Platinum drugs, such as cisplatin, carboplatin and oxaliplatin, are the mainstay of the metal-based compounds in the treatment of cancer, but the delay in the therapeutic accomplishment of other metal-based compounds hampered the progress of research in this field...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/28422935/the-baptist-health-nurse-retention-questionnaire-a-methodological-study-part-1
#13
Alexander Lengerich, Andrew Bugajski, Matthew Marchese, Brittany Hall, Susan Yackzan, Claire Davies, Dorothy Brockopp
OBJECTIVE: The purposes of this study were to develop and test the Baptist Health Nurse Retention Questionnaire (BHNRQ) and examine the importance of nurse retention factors. BACKGROUND: Multiple factors, including increasing patient acuity levels, have led to concerns regarding nurse retention. An understanding of current factors related to retention is limited. METHODS: To establish the psychometric properties of the BHNRQ, data were collected from 279 bedside nurses at a 391-bed, Magnet® redesignated community hospital...
May 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/28421225/using-telephony-data-to-facilitate-discovery-of-clinical-workflows
#14
Donald W Rucker
BACKGROUND:  Discovery of clinical workflows to target for redesign using methods such as Lean and Six Sigma is difficult. VoIP telephone call pattern analysis may complement direct observation and EMR-based tools in understanding clinical workflows at the enterprise level by allowing visualization of institutional telecommunications activity. OBJECTIVE:  To build an analytic framework mapping repetitive and high-volume telephone call patterns in a large medical center to their associated clinical units using an enterprise unified communications server log file and to support visualization of specific call patterns using graphical networks...
April 19, 2017: Applied Clinical Informatics
https://www.readbyqxmd.com/read/28418180/-little-things-matter-exploring-the-perspectives-of-patients-with-dementia-about-the-hospital-environment
#15
Lillian Hung, Alison Phinney, Habib Chaudhury, Paddy Rodney, Jenifer Tabamo, Doris Bohl
BACKGROUND: Recognising demographic changes and importance of the environment in influencing the care experience of patients with dementia, there is a need for developing the knowledge base to improve hospital environments. Involving patients in the development of the hospital environment can be a way to create more responsive services. To date, few studies have involved the direct voice of patients with dementia about their experiences of the hospital environment. DESIGN AND METHOD: Using an action research approach, we worked with patients with dementia and a team of interdisciplinary staff on a medical unit to improve dementia care...
April 18, 2017: International Journal of Older People Nursing
https://www.readbyqxmd.com/read/28416112/flexibility-and-design-conformational-heterogeneity-along-the-evolutionary-trajectory-of-a-redesigned-ubiquitin
#16
Justin T Biel, Michael C Thompson, Christian N Cunningham, Jacob E Corn, James S Fraser
Although protein design has been used to introduce new functions, designed variants generally only function as well as natural proteins after rounds of laboratory evolution. One possibility for this pattern is that designed mutants frequently sample nonfunctional conformations. To test this idea, we exploited advances in multiconformer modeling of room-temperature X-ray data collection on redesigned ubiquitin variants selected for increasing binding affinity to the deubiquitinase USP7. Initial core mutations disrupt natural packing and lead to increased flexibility...
April 12, 2017: Structure
https://www.readbyqxmd.com/read/28410694/pyridines-multidrug-resistant-tuberculosis-mdr-tb-inhibitors
#17
REVIEW
Kavita S Chaudhari, Harun M Patel, Sanjay J Surana
Mycobacterium tuberculosis (MTB) infection has become an increasing health threat due to the worldwide emergence of multidrug-resistant MTB (MDR-MTB) strain. Isoniazid (pyridine) resistance problem is a complex process and is associated with mutations in several genes. However, the emergence of isoniazid (INH) resistant M. tuberculosis strains dictates the necessity for redesigning this old drug in order to create analogs effective against INH-resistant strains by using rational approach. In light of these findings, the present review discusses the synthesis, structural optimization, and modification in pyridine structure to combat the problem of multidrug-resistant tuberculosis...
April 2017: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/28399387/redesigning-cancer-care-delivery-views-from-patients-and-caregivers
#18
Manali I Patel, Vyjeyanthi S Periyakoil, Douglas W Blayney, David Moore, Andrea Nevedal, Steven Asch, Arnold Milstein, Tumaini R Coker
INTRODUCTION: Cancer is a leading cause of death in the United States. Although treatments have improved, patients and caregivers continue to report significant gaps in their care. The objective of this study was to examine the views of patients and caregivers on their experiences with current cancer care delivery and identify key strategies to improve the delivery of care. METHODS AND MATERIALS: Semistructured interviews were conducted with 75 patients and 45 caregivers across the United States...
April 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28398255/robust-in-flight-sensor-fault-diagnostics-for-aircraft-engine-based-on-sliding-mode-observers
#19
Xiaodong Chang, Jinquan Huang, Feng Lu
For a sensor fault diagnostic system of aircraft engines, the health performance degradation is an inevitable interference that cannot be neglected. To address this issue, this paper investigates an integrated on-line sensor fault diagnostic scheme for a commercial aircraft engine based on a sliding mode observer (SMO). In this approach, one sliding mode observer is designed for engine health performance tracking, and another for sensor fault reconstruction. Both observers are employed in in-flight applications...
April 11, 2017: Sensors
https://www.readbyqxmd.com/read/28398225/a-low-cost-environmental-monitoring-system-how-to-prevent-systematic-errors-in-the-design-phase-through-the-combined-use-of-additive-manufacturing-and-thermographic-techniques
#20
Francesco Salamone, Ludovico Danza, Italo Meroni, Maria Cristina Pollastro
nEMoS (nano Environmental Monitoring System) is a 3D-printed device built following the Do-It-Yourself (DIY) approach. It can be connected to the web and it can be used to assess indoor environmental quality (IEQ). It is built using some low-cost sensors connected to an Arduino microcontroller board. The device is assembled in a small-sized case and both thermohygrometric sensors used to measure the air temperature and relative humidity, and the globe thermometer used to measure the radiant temperature, can be subject to thermal effects due to overheating of some nearby components...
April 11, 2017: Sensors
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