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https://www.readbyqxmd.com/read/28813474/binge-like-sucrose-consumption-reduces-the-dendritic-length-and-complexity-of-principal-neurons-in-the-adolescent-rat-basolateral-amygdala
#1
Masroor Shariff, Paul Klenowski, Michael Morgan, Omkar Patkar, Erica Mu, Mark Bellingham, Arnauld Belmer, Selena E Bartlett
A compelling body of evidence suggests that the worldwide obesity epidemic is underpinned by excessive sugar consumption, typified by the modern western diet. Furthermore, evidence is beginning to emerge of maladaptive changes in the mesolimbic reward pathway of the brain in relation to excess sugar consumption that highlights the importance of examining this neural circuitry in an attempt to understand and subsequently mitigate the associated morbidities with obesity. While the basolateral amygdala (BLA) has been shown to mediate the reinforcing properties of drugs of abuse, it has also been shown to play an important role in affective and motivated behaviours and has been shown to undergo maladaptive changes in response to drugs of abuse and stress...
2017: PloS One
https://www.readbyqxmd.com/read/28813108/consequences-of-gestational-diabetes-to-the-brain-and-behavior-of-the-offspring
#2
Ricardo A L DE Sousa, Yasmin S Torres, Claudia P Figueiredo, Giselle F Passos, Julia R Clarke
Gestational diabetes mellitus (GD) is a form of insulin resistance triggered during the second/third trimesters of pregnancy in previously normoglycemic women. It is currently estimated that 10% of all pregnancies in the United States show this condition. For many years, the transient nature of GD has led researchers and physicians to assume that long-term consequences were absent. However, GD diagnosis leads to a six-fold increase in the risk of developing type 2 diabetes (T2D) in women and incidence of obesity and T2D is also higher among their infants...
August 14, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28809783/role-of-omentin-vaspin-cardiotrophin-1-tweak-and-nov-ccn3-in-obesity-and-diabetes-development
#3
REVIEW
Xavier Escoté, Saioa Gómez-Zorita, Miguel López-Yoldi, Iñaki Milton-Laskibar, Alfredo Fernández-Quintela, J Alfredo Martínez, María J Moreno-Aliaga, María P Portillo
Adipose tissue releases bioactive mediators called adipokines. This review focuses on the effects of omentin, vaspin, cardiotrophin-1, Tumor necrosis factor-like Weak Inducer of Apoptosis (TWEAK) and nephroblastoma overexpressed (NOV/CCN3) on obesity and diabetes. Omentin is produced by the stromal-vascular fraction of visceral adipose tissue. Obesity reduces omentin serum concentrations and adipose tissue secretion in adults and adolescents. This adipokine regulates insulin sensitivity, but its clinical relevance has to be confirmed...
August 15, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28809754/associations-of-built-environment-and-children-s-physical-activity-a-narrative-review
#4
Houshmand E Masoumi
PROBLEM: Childhood obesity has been an epidemic particularly in high-income countries. There is a considerable volume of data and studies depicting the rising number of obese children and adolescents in different countries. As suggested by the literature, physical inactivity is one the main drivers of childhood obesity. This paper addresses the associations of the built environment with physical activity of children in order to find to theoretically facilitate intervention and prevention measures...
August 15, 2017: Reviews on Environmental Health
https://www.readbyqxmd.com/read/28809752/association-of-obesity-and-health-related-quality-of-life-in-iranian-children-and-adolescents-the-weight-disorders-survey-of-the-caspian-iv-study
#5
Silva Hovsepian, Mostafa Qorbani, Mohammad Esmaeil Motlagh, Aryan Madady, Morteza Mansourian, Armita Mahdavi Gorabi, Roya Kelishadi
BACKGROUND: Considering the role of different ethnical, cultural and geographical factors in health related quality of life (HRQOL) as well as the perception of different populations regarding various weight disorders, we aimed to evaluate the association between body mass index (BMI) and HRQOL in Iranian children and adolescents. METHODS: This cross-sectional study was part of the Weight Disorders Survey of the CASPIAN-IV study. During this study, students aged 6-18 years from urban and rural areas of 30 provinces of Iran were selected...
August 15, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28804978/birthweight-and-serum-uric-acid-in-american-adolescents
#6
Erika T Rhone, J Bryan Carmody
Elevated serum uric acid is associated with hypertension and chronic kidney disease. We evaluated the relationship between birthweight and uric acid in a nationally representative sample of 5390 US adolescents aged 12-15 in the National Health and Nutrition Examination Survey from 1999 to 2012. There was an inverse association between birthweight and uric acid after adjustment for sex, age, race, obesity, and dietary sodium intake. Each 1 kg increase in birthweight was associated with decreased uric acid by 0...
August 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28804649/trends-and-disparities-in-the-prevalence-of-childhood-obesity-in-south-texas-between-2009-and-2015
#7
Byron A Foster, Trevor M Maness, Christian A Aquino
BACKGROUND: Recent reports have highlighted possible decreases over time in obesity, particularly among children aged 2-5 years. Hispanic children experience significantly higher obesity rates, and less is known about trends for Hispanic children. METHODS: A large healthcare system-based dataset from south Texas was used to analyze body mass index (BMI) values obtained clinically from 2009 through 2015. Age and race/ethnicity specific prevalence of overweight and obesity were calculated using CDC standards and trends were examined over time using regression analyses, and mapping software was used to identify geographic variation...
2017: Journal of Obesity
https://www.readbyqxmd.com/read/28803504/the-pharmacological-management-of-nafld-in-children-and-adolescents
#8
Savinda Liyanagedera, Robert Patrick Williams, Silvio Veraldi, Valerio Nobili, Jake P Mann
Non-alcoholic fatty liver disease (NAFLD) represents a spectrum, including 'simple' steatosis, non-alcoholic steatohepatitis (NASH), and fibrosis. Increasing prevalence of NAFLD has followed the international rise in obesity and lifestyle modification is the mainstay therapy for children. To date, pharmacological trials have had varying efficacy but a large number of new agents are in early phase trials for adults. Areas covered: This review explores the effect of current and potential future paediatric NAFLD treatments in terms of histological and biochemical endpoints...
August 14, 2017: Expert Review of Clinical Pharmacology
https://www.readbyqxmd.com/read/28801145/body-image-dissatisfaction-and-dietary-patterns-according-to-nutritional-status-in-adolescents
#9
Rita de Cássia Ribeiro-Silva, Rosemeire Leovigildo Fiaccone, Maria Ester Pereira da Conceição-Machado, Ana Santos Ruiz, Maurício Lima Barreto, Mônica Leila Portela Santana
OBJECTIVE: There is a lack of data on the association between body self-perception and eating patterns in Brazil. Thus, this study aimed to explore the relationship between body image dissatisfaction (BID) and eating patterns by the anthropometric status in adolescents. METHODS: A cross-sectional study of 1496 adolescents was conducted. The participants completed the Body Shape Questionnaire. Demographic, anthropometric, and socioeconomic data were collected, as well as information regarding the pubertal development and dietary intake...
August 8, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28801068/lepr-polymorphism-may-affect-energy-balance-during-weight-loss-among-brazilians-obese-adolescents
#10
Flávia Campos Corgosinho, Sandro Soares Almeida, Lian Tock, João Bosco Pesquero, Ronaldo Carvalho Araújo, Ana Paula Grotti Clemente, Bárbara Dal'Molin Netto, Raquel Munhoz da Silveira Campos, Deborah Cristina Landi Masquio, Joana Pereira de Carvalho Ferreira, Priscila de Lima Sanches, Aline de Piano Ganen, Marcelo Macedo Rogero, Lila Missae Oyama, Sergio Tufik, Marco Túlio de Mello, Ana Raimunda Dâmaso
OBJECTIVE: Leptin is an adipokine released mainly by adipose tissue, with many functions including regulation of energy balance. However, little is known about the effect of LEPR polymorphism on orexigenic and anorexigenic neuropeptides. Thus, the aim of the present study is to verify the influence of LEPR polymorphism (rs2767485) on serum orexigenic (NPY, MCH and AgRP) and anorexigenic (Leptin and α-MSH) neuropeptides levels among obese adolescents submitted to 1year of multicomponent weight loss therapy...
August 2, 2017: Neuropeptides
https://www.readbyqxmd.com/read/28800913/-prevalence-of-hypovitaminosis-d-and-associated-factors-in-spanish-population-of-school-children-and-adolescents
#11
Teodoro Durá-Travé, Fidel Gallinas-Victoriano, María Jesús Chueca-Guindulain, Sara Berrade-Zubiri, Paula Moreno-Gónzalez, María Malumbres-Chacón
OBJECTIVE: To analyse the prevalence of hypovitaminosisD and associated factors in school children and adolescents living in a region of northern Spain. DESIGN: Cross-sectional study (convenience sampling). SETTING: Primary Health Care. PARTICIPANTS: A total of 602 Caucasian individuals (aged 3.1 to 15.4years) were included in the study. MAIN MEASUREMENTS: Prevalence of hypovitaminosisD were calculated (dependent variable)...
August 8, 2017: Atencion Primaria
https://www.readbyqxmd.com/read/28800814/phthalates-impact-human-health-epidemiological-evidences-and-plausible-mechanism-of-action
#12
REVIEW
Sailas Benjamin, Eiji Masai, Naofumi Kamimura, Kenji Takahashi, Robin C Anderson, Panichikkal Abdul Faisal
Disregarding the rising alarm on the hazardous nature of various phthalates and their metabolites, ruthless usage of phthalates as plasticizer in plastics and as additives in innumerable consumer products continues due low their cost, attractive properties, and lack of suitable alternatives. Globally, in silico computational, in vitro mechanistic, in vivo preclinical and limited clinical or epidemiological human studies showed that over a dozen phthalates and their metabolites ingested passively by man from the general environment, foods, drinks, breathing air, and routine household products cause various dysfunctions...
October 15, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28799060/association-between-anthropometric-indices-body-composition-and-bone-parameters-in-thai-female-adolescents
#13
Rapheeporn Khwanchuea, Chuchard Punsawad
OBJECTIVE: To investigate correlations between anthropometrics and body composition with bone parameters of the whole-body and lumbar spine in non-obese and obese Thai female adolescents. METHODS: This study was performed in 135 female adolescents aged 15 to 18 y enrolled in secondary schools in southern Thailand. Subjects were grouped into non-obesity (underweight and normal-to-overweight) (BMI < 25) and obesity (BMI ≥ 25) groups. Anthropometric indices for obesity [body weight (BW), waist circumference (WC), and body mass index (BMI)] were recorded...
August 11, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28799014/breakfast-habits-dairy-product-consumption-physical-activity-and-their-associations-with-body-mass-index-in-children-aged-6-18
#14
Tugba Koca, Mustafa Akcam, Filiz Serdaroglu, Selim Dereci
The purpose of this study was to determine breakfast habits, dairy product consumption, and physical activity and their relations with body mass index (BMI) in schoolchildren and adolescents. This cross-sectional, school-based study was performed with children aged 6-18 years. Height and weight were measured, and a BMI z-score was calculated for each child. Breakfast consumption frequency, intake of milk and other dairy products, physical activity habits, and mothers' employment status were assessed via a self-report questionnaire...
August 11, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28794094/outcomes-of-50-patients-entering-an-adolescent-bariatric-surgery-programme
#15
Billy White, Jacqueline Doyle, Kirsten Matschull, Marco Adamo, Deborah Christie, Dasha Nicholls, Sanjay Kinra, Ian Chi Kei Wong, Russell M Viner
OBJECTIVE: Bariatric surgery is the most effective intervention for weight loss and obesity-related comorbidities currently available. Little is known about adolescents entering National Health Service (NHS) bariatric programmes. We aimed to characterise those entering a pathway and report their outcomes. DESIGN: Prospective service evaluation of patients assessed within a single NHS adolescent bariatric service. RESULTS: 50 patients assessed between 26 July 2007 and 27 January 2014; 6 (12%) were not eligible for surgery, 7 (14%) actively opted out, 8 (16%) were lost to follow-up and 29 (58%) underwent surgery (18 sleeve gastrectomy (SG) 11 Roux-en-y gastric bypass (RYGB) and 0 adjustable gastric band)...
August 9, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28794060/assessment-of-health-related-quality-of-life-and-psychological-well-being-of-children-and-adolescents-with-obesity-enrolled-in-a-new-zealand-community-based-intervention-programme-an-observational-study
#16
Yvonne C Anderson, Lisa E Wynter, Katharine F Treves, Cameron C Grant, Joanna M Stewart, Tami L Cave, Trecia A Wouldes, José G B Derraik, Wayne S Cutfield, Paul L Hofman
OBJECTIVE: To describe health-related quality of life (HRQOL) and psychological well-being of children and adolescents at enrolment in a multidisciplinary community-based obesity programme and to determine association with ethnicity. This programme targeted indigenous people and those from most deprived households. Further, this cohort was compared with other populations/normative data. METHODS: This study examines baseline demographic data of an unblinded randomised controlled clinical trial...
August 9, 2017: BMJ Open
https://www.readbyqxmd.com/read/28793946/training-primary-care-providers-in-the-use-of-motivational-interviewing-for-youth-behavior-change
#17
Monique K Vallabhan, Alberta S Kong, Elizabeth Yakes Jimenez, Linda C Summers, Conni J DeBlieck, Sarah W Feldstein Ewing
BACKGROUND AND PURPOSE: Adolescent obesity is a global epidemic. Motivational interviewing (MI) is a promising strategy to address adolescent obesity risk behaviors. However, primary care providers (PCPs) tend to express discomfort with learning and adopting MI practices and with addressing patient weight issues. PCP proficiency in using MI to discuss body mass index, health screening results, and nutrition and physical activity behaviors after receiving training and coaching from an MI expert and practicing the technique was evaluated...
August 1, 2017: Research and Theory for Nursing Practice
https://www.readbyqxmd.com/read/28793889/high-burden-of-hypertension-across-the-age-groups-among-residents-of-gondar-city-in-ethiopia-a-population-based-cross-sectional-study
#18
Abayneh Girma Demisse, Ermias Shenkutie Greffie, Solomon Mekonnen Abebe, Abera Balcha Bulti, Shitaye Alemu, Bewketu Abebe, Nebiyu Mesfin
BACKGROUND: According to a report on the worldwide trends in blood pressure from 1975 to 2015, mean blood pressure is increasing in low and middle income countries while it is either decreasing or stabilizing in high income countries. Few studies have been published on the prevalence of hypertension in Ethiopia demonstrating an increased trend; however, these studies had small sample size and were limited to participants older than 35 years; which left the burden among adolescents and young adults unaddressed...
August 9, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28792151/physical-activity-sedentary-habits-sleep-and-obesity-are-associated-with-asthma-allergic-rhinitis-and-atopic-dermatitis-in-korean-adolescents
#19
Man Sup Lim, Chang Hee Lee, Songyong Sim, Sung Kwang Hong, Hyo Geun Choi
PURPOSE: Since pathophysiologic evidence has been raised to suggest that obesity could facilitate an allergic reaction, obesity has been known as an independent risk factor for allergic disease such as asthma. However, the relationship between sedentary behavior and lifestyle which could lead to obesity, and those allergic diseases remains unclear. MATERIALS AND METHODS: We analyzed the relations between physical activity, including sitting time for study, sitting time for leisure and sleep time, and obesity, asthma, allergic rhinitis, and atopic dermatitis using the Korea Youth Risk Behavior Web-based Survey, which was conducted in 2013...
September 2017: Yonsei Medical Journal
https://www.readbyqxmd.com/read/28791978/comparison-of-obesity-overweight-and-elevated-blood-pressure-in-children-attending-public-and-private-primary-schools-in-benin-city-nigeria
#20
W E Sadoh, Y T Israel-Aina, A E Sadoh, J E Uduebor, M Shaibu, E Ogonor, F C Enugwuna
BACKGROUND: Overweight and obesity in children, and adolescents is on the rise globally. Affected children are prone to cardio-metabolic problems later in life, especially hypertension. The prevalence of obesity/overweight may differ depending on school type. Private schools are attended mostly by children of the affluent, while public schools are attended predominantly by those in the low and middle socio-economic classes. OBJECTIVE: To compare the prevalence of overweight, obesity and elevated blood pressure (BP) in pupils attending public and private primary schools in an urban community in Nigeria...
July 2017: Nigerian Journal of Clinical Practice
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