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Hoffa's fat pad

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https://www.readbyqxmd.com/read/29651769/superolateral-hoffa-s-fat-pad-shfp-oedema-and-patellar-cartilage-volume-loss-quantitative-analysis-using-longitudinal-data-from-the-foundation-for-the-national-institute-of-health-fnih-osteoarthritis-biomarkers-consortium
#1
Arya Haj-Mirzaian, Ali Guermazi, Nima Hafezi-Nejad, Christopher Sereni, Michael Hakky, David J Hunter, Bashir Zikria, Frank W Roemer, Shadpour Demehri
OBJECTIVES: To determine the association of superolateral Hoffa's fat pad (SHFP) oedema and patellofemoral joint structural damage in participants of Foundation for the National Institute of Health Osteoarthritis Biomarkers Consortium study. METHODS: Baseline and 24-month MRIs of 600 subjects were assessed. The presence of SHFP oedema (using 0-3 grading scale) and patellar morphology metrics were determined using baseline MRI. Quantitative patellar cartilage volume and semi-quantitative MRI osteoarthritis knee score (MOAKS) variables were extracted...
April 12, 2018: European Radiology
https://www.readbyqxmd.com/read/29578896/herniation-of-hoffa-s-fat-pad-through-the-lateral-retinaculum-usefulness-of-dynamic-ultrasonography-to-diagnose-a-lateral-knee-mass
#2
Kamal Mezian, Ke-Vin Chang, David Zámečník, Hassan Mezian, Levent Özçakar
No abstract text is available yet for this article.
March 24, 2018: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/29556503/the-unexplored-role-of-intra-articular-adipose-tissue-in-the-homeostasis-and-pathology-of-articular-joints
#3
Luminita Labusca, Florin Zugun-Eloae
Intra-articular adipose tissue deposits known as articular fat pads (AFPs) are described to exist within synovial joints. Their assumed role in normal joint biomechanics is increasingly objectivized by means of advanced methods of functional imaging. AFPs possess structural similarity with body subcutaneous white adipose tissue (WAT), however, seems to be regulated by independent metabolic loops. AFP dimension are conserved during extreme WAT states: obesity, metabolic syndrome, lipodystrophy, and cachexia...
2018: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29438603/from-early-radiographic-knee-osteoarthritis-to-joint-arthroplasty-determinants-of-structural-progression-and-symptoms
#4
Frank W Roemer, C Kent Kwoh, Tomoko Fujii, Michael J Hannon, Robert M Boudreau, David J Hunter, Felix Eckstein, Markus R John, Ali Guermazi
OBJECTIVE: Aims were to assess (1) structural progression in knees with no/mild radiographic osteoarthritis (ROA) (i.e. Kellgren-Lawrence (K-L) grades 0 to 2) that will undergo knee replacement (KR) during a 5-year period; (2) differences in structural damage on MRI between knees with no/mild ROA vs. those with severe ROA (i.e. K-L 3 and 4) at baseline; and (3) differences in pain levels between those groups. METHODS: All participants who underwent KR from baseline (BL) to 60 months were drawn from the Osteoarthritis Initiative...
February 13, 2018: Arthritis Care & Research
https://www.readbyqxmd.com/read/29426013/celecoxib-mediated-reduction-of-prostanoid-release-in-hoffa-s-fat-pad-from-donors-with-cartilage-pathology-results-in-an-attenuated-inflammatory-phenotype
#5
U T Timur, M M J Caron, Y M Bastiaansen-Jenniskens, T J M Welting, L W van Rhijn, G J V M van Osch, P J Emans
OBJECTIVE: The Hoffa's fat pad (HFP) is an intra-articular adipose tissue which is situated under and behind the patella. It contains immune cells next to adipocytes and secretes inflammatory factors during osteoarthritis (OA). In this study, we compared the release profile of prostanoids, which are involved in inflammation, of HFP from OA patients vs patients with a focal cartilage defect (CD) without evidence for OA on MRI and investigated the prostanoid modulatory anti-inflammatory action of celecoxib on HFP...
May 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29205448/soft-tissue-masses-of-the-knee-related-to-a-focal-defect-of-the-lateral-patellar-retinaculum
#6
Antoine Moraux, Stefano Bianchi, Thomas Le Corroller
We report on the imaging features of 6 soft tissue masses in the anterolateral aspect of the knee related to a focal defect of the lateral patellar retinaculum. In 4 patients (3 female and 1 male; 6-65 years) presenting with nontender palpable soft tissue masses in the anterolateral aspect of their knees, ultrasonography showed a focal defect of the lateral patellar retinaculum with herniation of the Hoffa fat pad, which was only visible in flexion. A magnetic resonance imaging examination performed in 1 case confirmed the defect in the lateral patellar retinaculum but did not show a mass, as the knee was examined only at 10° of flexion...
December 4, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/29163952/in-office-arthroscopy-for-the-evaluation-of-chronic-knee-pain-a-case-report
#7
Jacob A West, Nirav H Amin
This is a case report detailing the use of in-office needle arthroscopy (mi-eye 2™) in a patient with chronic knee pain and inconclusive magnetic resonance imaging findings. The patient is a 40-year-old male who presented to our clinic after an extended history of right knee pain along the medial aspect with previous failed treatments. Magnetic resonance imaging without contrast had demonstrated full-thickness chondral fissuring of the lateral patellar facet, mild abnormal signals of the proximal patellar tendon and Hoffa's fat pad, and intact anterior cruciate ligament and posterior cruciate ligament...
2017: SAGE Open Medical Case Reports
https://www.readbyqxmd.com/read/29156945/modulation-of-gene-expression-in-infrapatellar-fat-pad-derived-mesenchymal-stem-cells-in-osteoarthritis
#8
Beatriz Bravo, Jose Manuel Argüello, Arancha R Gortazar, Francisco Forriol, Javier Vaquero
Aim In the osteoarthritis (OA) disease, all structures of the joint are involved. The infrapatellar Hoffa fat pad is rich in macrophages and granulocytes, which also represents a source of adipose mesenchymal progenitor cells (ASC) cells. In our study, we analyze how OA affects the ability of ASC-derived from Hoffa's fat pad to differentiate into chondrocytes. Material and methodology We took knee Hoffa's pad samples and adipose tissue from the proximal thigh from 6 patients diagnosed with severe OA and from another 6 patients with an anterior cruciate ligament (ACL) rupture without OA...
January 2018: Cartilage
https://www.readbyqxmd.com/read/29089000/ununited-bone-ossicle-in-a-patient-with-patellar-tendinopathy
#9
Emily B Beyer, Elena J Jelsing, Wendy J Hurd
A 40-year-old man presented to a physician for knee pain when squatting and in resisted knee extension. The initial diagnosis was patellar tendinopathy. Following physical therapy treatment, a sports medicine physician was consulted for a second opinion. Radiography, diagnostic ultrasound, and magnetic resonance imaging were performed, confirming the original diagnosis and revealing Hoffa's fat pad impingement secondary to an ununited ossicle. J Orthop Sports Phys Ther 2017;47(11):885. doi:10.2519/jospt.2017...
November 2017: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/28993563/mri-findings-consistent-with-peripatellar-fat-pad-impingement-how-much-related-to-patellofemoral-maltracking
#10
Mohamed Jarraya, Luis E Diaz, Frank W Roemer, William F Arndt, Ajay R Goud, Ali Guermazi
Peripatellar fat pads are intracapsular extrasynovial adipose cushions that accommodate the changing shape and volume of articular spaces during movement. Variations in bone geometry, passive and active stabilization mechanisms and/or functional demands may lead to peripatellar fat pad abnormalities. While peripatellar fat pads may be affected a variety of conditions such as synovial inflammation, tumor and fibrosis, a mechanical origin should also be considered. Commonly, the clinical term "impingement" is used synonymously in the radiological literature to refer to three distinct entities of structural peripatellar fat pad abnormalities: superolateral the infrapatellar fat pad (Hoffa fat pad) edema, suprapatellar fat pad edema, and prepatellar fat pad edema, implying a mechanical origin of these conditions...
October 10, 2017: Magnetic Resonance in Medical Sciences: MRMS
https://www.readbyqxmd.com/read/28893388/the-imaging-findings-of-impingement-syndromes-of-the-lower-limb
#11
REVIEW
M De Maeseneer, S Wuertzer, J de Mey, M Shahabpour
In this article we provide an overview of impingement syndromes of the lower limb. At the level of the hip, femoroacetabular and ischiofemoral impingement are recognised. At the level of the knee, we discuss Hoffa's fat pad impingement, suprapatellar fat pad impingement, pericruciate impingement, and iliotibial band syndrome. The impingement syndromes associated with anterior cruciate ligament (ACL) repair and intercondylar osteophytes are also illustrated. Most impingement syndromes are described at the level of the ankle...
December 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28770522/hoffa-s-fat-pad-abnormality-in-the-development-of-knee-osteoarthritis
#12
Wojciech Paduszyński, Mateusz Jeśkiewicz, Paweł Uchański, Sebastian Gackowski, Marek Radkowski, Urszula Demkow
Over the past two decades, many hypotheses have been put forward to explain the cause of knee osteoarthritis. Scientific reports bring up the role of adipose tissue in the activation of the inflammatory mechanisms, which is a characteristic feature of osteoarthritis natural history. Adipose tissue produces and releases cytokines, interleukins, and growth factors by means of paracrine, endocrine, and autocrine mechanisms. Hoffa's fat pad (infrapatellar adipose tissue) plays a viable role in the initiation and progression of osteoarthritis due to its role in the activation and release of pro-inflammatory mediators...
2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28668541/non-linear-optical-microscopy-as-a-novel-quantitative-and-label-free-imaging-modality-to-improve-the-assessment-of-tissue-engineered-cartilage
#13
A Islam, E I Romijn, M B Lilledahl, I Martinez-Zubiaurre
OBJECTIVE: Current systems to evaluate outcomes from tissue-engineered cartilage (TEC) are sub-optimal. The main purpose of our study was to demonstrate the use of second harmonic generation (SHG) microscopy as a novel quantitative approach to assess collagen deposition in laboratory made cartilage constructs. METHODS: Scaffold-free cartilage constructs were obtained by condensation of in vitro expanded Hoffa's fat pad derived stromal cells (HFPSCs), incubated in the presence or absence of chondrogenic growth factors (GF) during a period of 21 d...
June 29, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28656366/biographical-background-and-origin-of-common-eponymous-terms-in-orthopedic-surgery-anatomy-and-fractures-in-knee-surgery
#14
Matthijs P Somford, Rebecca A Nieuwe Weme, Daniël Hoornenborg, Johannes I Wiegerinck, Jos J A M van Raay, Reinoud W Brouwer, Andy Williams
An eponym is a person after whom an eponymous term is named. These eponymous terms are easy shorthand in communication between surgeons. Therefore, they are often used and hard to eradicate. We discuss eponymous terms that describe anatomical features and fracture types in the knee. With these terms, an overview of the historical background of the eponym and its current clinical implication is discussed. The eponymous terms discussed are Gerdy tubercle, Pellegrini-Stieda lesion, Segond fracture, Hoffa fracture and fat pad...
January 2018: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/28606557/is-superolateral-hoffa-s-fat-pad-hyperintensity-a-marker-of-local-patellofemoral-joint-disease-the-most-study
#15
M Jarraya, A Guermazi, D T Felson, F W Roemer, M C Nevitt, J Torner, C E Lewis, J J Stefanik
PURPOSE: To determine the relation of superolateral Hoffa's fat pad (SHFP) hyperintensity to cartilage damage and bone marrow lesions (BMLs) in the patellofemoral joint (PFJ) and tibiofemoral joint (TFJ). METHODS: We used data from the 60 and 84-month study visits from the Multicenter Osteoarthritis (MOST) study. SHFP hyperintensity and Hoffa-synovitis were graded from 0 to 3. Cartilage damage and BMLs were scored in the PFJ and TFJ. Structural damage was defined as: any cartilage damage, full-thickness cartilage damage and any BML...
September 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28418810/relationship-of-trochlear-morphology-and-patellofemoral-joint-alignment-to-superolateral-hoffa-fat-pad-edema-on-mr-images-in-individuals-with-or-at-risk-for-osteoarthritis-of-the-knee-the-most-study
#16
Rafael Widjajahakim, Michael Roux, Mohamed Jarraya, Frank W Roemer, Tuhina Neogi, John A Lynch, Cora E Lewis, James C Torner, David T Felson, Ali Guermazi, Joshua J Stefanik
Purpose To determine the relationship of patellofemoral joint alignment and trochlear morphology to superolateral Hoffa fat pad (SHFP) edema on magnetic resonance (MR) images in older adults with or at risk for osteoarthritis of the knee. Materials and Methods Institutional review board approval and written informed consent were obtained from all subjects. The Multicenter Osteoarthritis Study is a prospective cohort study of older adults with or at risk for osteoarthritis of the knee. Subjects were recruited from Birmingham, Alabama, and Iowa City, Iowa...
September 2017: Radiology
https://www.readbyqxmd.com/read/28411875/association-between-lateral-patellar-osteoarthrosis-and-knee-morphology-and-alignment-in-young-adults
#17
R Sebro, S Weintraub
AIM: To assess whether patellar and trochlea morphology and patellar alignment are associated with lateral patellar osteoarthrosis/chondrosis (OAC) in young adults. MATERIALS AND METHODS: Magnetic resonance imaging (MRI) images of 183 subjects (81 cases, 102 controls) aged 21-35 years of age were evaluated. Quantitative measurements of patella and trochlea morphology and patellar alignment were obtained. Axial and sagittal MRI images were reviewed to grade the severity of focal cartilage defects along the lateral facet of the patella...
September 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28237607/knee-morphometric-and-alignment-measurements-with-mr-imaging-in-young-adults-with-central-cartilage-lesions-of-the-patella-and-trochlea
#18
R Sebro, S Weintraub
PURPOSE: The goal of this study was to assess whether common measurements of patellar and trochlear morphology and patellar alignment are associated with central cartilage lesions of the patella and trochlea using magnetic resonance imaging (MRI). METHODS: The MRI examinations of 58 patients (38 women, 20 men; mean age, 28.59 years [range: 19-35 years]) with central cartilage lesions of the patella and trochlea were retrospectively compared to those obtained in 102 control subjects (57 women, 45 men; mean age, 27...
May 2017: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/28132101/sonographic-characterization-of-hoffa-s-fat-pad-a-pilot-study
#19
Erika Vera-Pérez, Guadalupe Sánchez-Bringas, Lucio Ventura-Ríos, Cristina Hernández-Díaz, Socorro Cortés, Marwin Gutiérrez, Carlos Pineda
This study addresses a topic that was previously unaddressed in the literature: the normal sonographic appearance of the Hoffa's fat pad (HFP) in young, asymptomatic subjects. The aim of the study is to describe the sonoanatomical features of HFP, including its echostructure, echogenicity, elasticity, and vascularization, in subjects without knee pathology. Knees of healthy subjects were examined with grayscale ultrasound (US) to determine the sonographic characteristics of the HFP. Echogenicity was assessed by pixel intensity quantification...
May 2017: Rheumatology International
https://www.readbyqxmd.com/read/28130075/synovial-chondroma-in-hoffa-s-fat-pad-case-report-and-literature-review-of-a-rare-disorder
#20
Lauren O'Connell, Adeel R Memon, Paul Foran, Eamon Leen, Patrick J Kenny
INTRODUCTION: Synovial chrondomatosis is a rare disorder characterised by the development of hyaline cartilage from the synovial membrane. Large isolated lesions in the Hoffa's fat pad are an uncommon entity. PRESENTATION OF CASE: A 33 year old gentleman presented complaining of progressive knee pain associated with an enlarging lesion on the anterior aspect of the right knee, with associated locking and giving way. Examination revealed a firm 4×5cm lesion adjacent to the patellar tendon...
2017: International Journal of Surgery Case Reports
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