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Hoffa's fat pad

M De Maeseneer, S Wuertzer, J de Mey, M Shahabpour
In this article we provide an overview of impingement syndromes of the lower limb. At the level of the hip, femoroacetabular and ischiofemoral impingement are recognised. At the level of the knee, we discuss Hoffa's fat pad impingement, suprapatellar fat pad impingement, pericruciate impingement, and iliotibial band syndrome. The impingement syndromes associated with anterior cruciate ligament (ACL) repair and intercondylar osteophytes are also illustrated. Most impingement syndromes are described at the level of the ankle...
September 8, 2017: Clinical Radiology
Wojciech Paduszyński, Mateusz Jeśkiewicz, Paweł Uchański, Sebastian Gackowski, Marek Radkowski, Urszula Demkow
Over the past two decades, many hypotheses have been put forward to explain the cause of knee osteoarthritis. Scientific reports bring up the role of adipose tissue in the activation of the inflammatory mechanisms, which is a characteristic feature of osteoarthritis natural history. Adipose tissue produces and releases cytokines, interleukins, and growth factors by means of paracrine, endocrine, and autocrine mechanisms. Hoffa's fat pad (infrapatellar adipose tissue) plays a viable role in the initiation and progression of osteoarthritis due to its role in the activation and release of pro-inflammatory mediators...
August 3, 2017: Advances in Experimental Medicine and Biology
A Islam, E I Romijn, M B Lilledahl, I Martinez-Zubiaurre
OBJECTIVE: Current systems to evaluate outcomes from tissue-engineered cartilage (TEC) are sub-optimal. The main purpose of our study was to demonstrate the use of second harmonic generation (SHG) microscopy as a novel quantitative approach to assess collagen deposition in laboratory made cartilage constructs. METHODS: Scaffold-free cartilage constructs were obtained by condensation of in vitro expanded Hoffa's fat pad derived stromal cells (HFPSCs), incubated in the presence or absence of chondrogenic growth factors (GF) during a period of 21 d...
June 29, 2017: Osteoarthritis and Cartilage
Matthijs P Somford, Rebecca A Nieuwe Weme, Daniël Hoornenborg, Johannes I Wiegerinck, Jos J A M van Raay, Reinoud W Brouwer, Andy Williams
An eponym is a person after whom an eponymous term is named. These eponymous terms are easy shorthand in communication between surgeons. Therefore, they are often used and hard to eradicate. We discuss eponymous terms that describe anatomical features and fracture types in the knee. With these terms, an overview of the historical background of the eponym and its current clinical implication is discussed. The eponymous terms discussed are Gerdy tubercle, Pellegrini-Stieda lesion, Segond fracture, Hoffa fracture and fat pad...
June 27, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
M Jarraya, A Guermazi, D T Felson, F W Roemer, M C Nevitt, J Torner, C E Lewis, J J Stefanik
PURPOSE: To determine the relation of superolateral Hoffa's fat pad (SHFP) hyperintensity to cartilage damage and bone marrow lesions (BMLs) in the patellofemoral joint (PFJ) and tibiofemoral joint (TFJ). METHODS: We used data from the 60 and 84-month study visits from the Multicenter Osteoarthritis (MOST) study. SHFP hyperintensity and Hoffa-synovitis were graded from 0 to 3. Cartilage damage and BMLs were scored in the PFJ and TFJ. Structural damage was defined as: any cartilage damage, full-thickness cartilage damage and any BML...
September 2017: Osteoarthritis and Cartilage
Rafael Widjajahakim, Michael Roux, Mohamed Jarraya, Frank W Roemer, Tuhina Neogi, John A Lynch, Cora E Lewis, James C Torner, David T Felson, Ali Guermazi, Joshua J Stefanik
Purpose To determine the relationship of patellofemoral joint alignment and trochlear morphology to superolateral Hoffa fat pad (SHFP) edema on magnetic resonance (MR) images in older adults with or at risk for osteoarthritis of the knee. Materials and Methods Institutional review board approval and written informed consent were obtained from all subjects. The Multicenter Osteoarthritis Study is a prospective cohort study of older adults with or at risk for osteoarthritis of the knee. Subjects were recruited from Birmingham, Alabama, and Iowa City, Iowa...
September 2017: Radiology
R Sebro, S Weintraub
AIM: To assess whether patellar and trochlea morphology and patellar alignment are associated with lateral patellar osteoarthrosis/chondrosis (OAC) in young adults. MATERIALS AND METHODS: Magnetic resonance imaging (MRI) images of 183 subjects (81 cases, 102 controls) aged 21-35 years of age were evaluated. Quantitative measurements of patella and trochlea morphology and patellar alignment were obtained. Axial and sagittal MRI images were reviewed to grade the severity of focal cartilage defects along the lateral facet of the patella...
September 2017: Clinical Radiology
R Sebro, S Weintraub
PURPOSE: The goal of this study was to assess whether common measurements of patellar and trochlear morphology and patellar alignment are associated with central cartilage lesions of the patella and trochlea using magnetic resonance imaging (MRI). METHODS: The MRI examinations of 58 patients (38 women, 20 men; mean age, 28.59 years [range: 19-35 years]) with central cartilage lesions of the patella and trochlea were retrospectively compared to those obtained in 102 control subjects (57 women, 45 men; mean age, 27...
May 2017: Diagnostic and Interventional Imaging
Erika Vera-Pérez, Guadalupe Sánchez-Bringas, Lucio Ventura-Ríos, Cristina Hernández-Díaz, Socorro Cortés, Marwin Gutiérrez, Carlos Pineda
This study addresses a topic that was previously unaddressed in the literature: the normal sonographic appearance of the Hoffa's fat pad (HFP) in young, asymptomatic subjects. The aim of the study is to describe the sonoanatomical features of HFP, including its echostructure, echogenicity, elasticity, and vascularization, in subjects without knee pathology. Knees of healthy subjects were examined with grayscale ultrasound (US) to determine the sonographic characteristics of the HFP. Echogenicity was assessed by pixel intensity quantification...
May 2017: Rheumatology International
Lauren O'Connell, Adeel R Memon, Paul Foran, Eamon Leen, Patrick J Kenny
INTRODUCTION: Synovial chrondomatosis is a rare disorder characterised by the development of hyaline cartilage from the synovial membrane. Large isolated lesions in the Hoffa's fat pad are an uncommon entity. PRESENTATION OF CASE: A 33 year old gentleman presented complaining of progressive knee pain associated with an enlarging lesion on the anterior aspect of the right knee, with associated locking and giving way. Examination revealed a firm 4×5cm lesion adjacent to the patellar tendon...
2017: International Journal of Surgery Case Reports
Chiara Giulia Fontanella, Emanuele Luigi Carniel, Alessandro Frigo, Veronica Macchi, Andrea Porzionato, Gloria Sarasin, Marco Rossato, Raffaele De Caro, Arturo N Natali
The infrapatellar adipose body (Hoffa's fat pad, IFP) is situated between the patellar tendon, the femoral condyle and the tibial plateau. The IFP consists of lobules of white adipose tissue delimited by thin connective septa. The actual structural functionality of the IFP is debated and should pertain to a cushioning role in the knee joint, providing to distribute and to damp mechanical stresses during articular activity. The present study is aimed to analyze the correlation between histological configuration and mechanical properties of the IFP, compared to other adipose tissues, partially differentiated by composition and conformation...
December 1, 2016: Journal of the Mechanical Behavior of Biomedical Materials
Partha Saha, Utpal Bandyopadhyay, Anindya S Mukhopadhyay, Srikanta Kundu, Subhadip Mandal
INTRODUCTION: Intra-articular ganglion cysts of the knee joint are rare occurrences. They are usually encountered as incidental findings in magnetic resonance imaging (MRI), or in arthroscopy. They may originate from both the cruciate ligaments and the menisci, from the popliteus tendon and alar folds, infrapatellar fat pad of Hoffa, and subchondral bone cysts. Those arising from the Hoffa's fat pad, usually present as palpable mass at anterior aspect of the knee joint. We report a case of intraarticular ganglion cyst of knee arising from the infrapatellar fat pad and protruding anterolaterally through retinacular rent into the subcutaneous plane...
July 2015: Journal of Orthopaedic Case Reports
A Islam, A K Hansen, C Mennan, I Martinez-Zubiaurre
Many researchers world over are currently investigating the suitability of stromal cells harvested from foetal tissues for allogeneic cell transplantation therapies or for tissue engineering purposes. In this study, we have investigated the chondrogenic potential of mesenchymal stromal cells (MSCs) isolated from whole sections of human umbilical cord or mixed cord (UCSCs-MC), and compared them with cells isolated from synovial membrane (SMSCs), Hoffa's fat pad (HFPSCs) and cartilage. All MSCs were positive for surface markers including CD73, CD90, CD105, CD44, CD146 and CD166, but negative for CD11b, CD19, CD34, CD45 and HLA-DR in addition to CD106 and CD271...
May 27, 2016: European Cells & Materials
Chermaine Deepa Antony, John George, Wuey Min Ng, Manimalar Selvi Naicker Subramaniam
Purpose. This study investigates the association between focal nodular mass with low signal in Hoffa's fat pad adjacent to anterior femoral cartilage of the knee (FNMHF) and focal cartilage abnormality in this region. Method. The magnetic resonance fast imaging employing steady-state acquisition sequence (MR FIESTA) sagittal and axial images of the B1 and C1 region (described later) of 148 patients were independently evaluated by two reviewers and categorized into four categories: normal, FNMHF with underlying focal cartilage abnormality, FNMHF with normal cartilage, and cartilage abnormality with no FNMHF...
2016: Scientifica
Rianne A van der Heijden, Janneke L M de Kanter, Sita M A Bierma-Zeinstra, Jan A N Verhaar, Peter L J van Veldhoven, Gabriel P Krestin, Edwin H G Oei, Marienke van Middelkoop
BACKGROUND: Structural abnormalities of the patellofemoral joint might play a role in the pathogenesis of patellofemoral pain (PFP), a common knee problem among young and physically active individuals. No previous study has investigated if PFP is associated with structural abnormalities of the patellofemoral joint using high-resolution magnetic resonance imaging (MRI). PURPOSE: To investigate the presence of structural abnormalities of the patellofemoral joint on high-resolution MRI in patients with PFP compared with healthy control subjects...
September 2016: American Journal of Sports Medicine
F Lapègue, N Sans, C Brun, S Bakouche, N Brucher, Z Cambon, H Chiavassa, A Larbi, M Faruch
Fat is not just used by the body as bulk tissue. In addition to its role in storing energy and regulating hormone action, fat is used in some parts of the body for its mechanical properties. The anatomy of anterior knee fat is more complex than it appears at first sight and is capable of withstanding considerable compressive and shear stress. Specific lesions occur when such mechanical stress exceeds the physiological limits and are yet little known. Superficial fat can be the site of either acute injury by closed degloving called the Morel-Lavallée lesion or chronic injury, when subject to repeat excessive shear forces, due to more complex and less well-defined disruptions that result in pseudo-bursitis...
July 2016: Diagnostic and Interventional Imaging
Florent Eymard, Xavier Chevalier
The infrapatellar fat pad (IFP) of Hoffa's fat pad is the main adipose structure within the knee joint. It is located between the joint capsule and the synovial membrane, which lines its posterior aspect. The IFP is composed chiefly of adipocytes and receives an abundant supply of blood vessels and nerves. Immune cells can infiltrate the IFP, which can become a major source of numerous proinflammatory mediators (cytokines and adipokines). The physiological role for the IFP remains unclear but may involve shock absorption and the protection of adjacent tissues...
July 2016: Joint, Bone, Spine: Revue du Rhumatisme
F Draghi, G Ferrozzi, L Urciuoli, C Bortolotto, S Bianchi
Hoffa's (infrapatellar) fat pad (HFP) is one of the knee fat pads interposed between the joint capsule and the synovium. Located posterior to patellar tendon and anterior to the capsule, the HFP is richly innervated and, therefore, one of the sources of anterior knee pain. Repetitive local microtraumas, impingement, and surgery causing local bleeding and inflammation are the most frequent causes of HFP pain and can lead to a variety of arthrofibrotic lesions. In addition, the HFP may be secondarily involved to menisci and ligaments disorders, injuries of the patellar tendon and synovial disorders...
June 2016: Insights Into Imaging
James Mace, Waqar Bhatti, Sanjay Anand
The infrapatellar (Hoffa's) fatpad is an important structure within the knee, whose function and role are both poorly understood. This review explores the anatomy, neural innervation, vascularity, role in biomechanics, pathology, imaging (stressing the importance of dynamic ultrasound assessment) and treatment of disorders presenting within this structure.
March 2016: Acta Orthopaedica Belgica
Valeria Beltrame, Giovanna Romanucci, Francesco Zulian, Roberto Stramare
No abstract text is available yet for this article.
May 2016: Journal of Pediatrics
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