keyword
MENU ▼
Read by QxMD icon Read
search

modic

keyword
https://www.readbyqxmd.com/read/29763470/the-influence-of-spinal-pelvic-parameters-on-the-prevalence-of-endplate-modic-changes-in-degenerative-thoracolumbar-lumbar-kyphosis-patients
#1
Weiwei Xia, Chenjun Liu, Shuo Duan, Shuai Xu, Kaifeng Wang, Zhenqi Zhu, Haiying Liu
BACKGROUND: The typical degeneration of the vertebral endplate shown in MRI imaging is Modic change. The aim of this study was to observe the distribution of the Modic changes of vertebral endplate in degenerative thoracolumbar/lumbar kyphosis (DTK/LK) patients and analyse the correlation between spinal-pelvic parameters and Modic changes. METHODS: The imaging data of 58 patients diagnosed with DTK/LK (coronal Cobb angle<10°with sagittal imbalance) in our hospital from March 2016 to May 2017 were reviewed retrospectively...
2018: PloS One
https://www.readbyqxmd.com/read/29713411/percutaneous-endoscopic-cervical-discectomy-surgical-approaches-and-postoperative-imaging-changes
#2
Shu Nakamura, Mitsuto Taguchi
Study Design: Retrospective clinical study. Purpose: This study investigated the relationship between surgical approaches and surgical outcomes in patients undergoing percutaneous endoscopic cervical discectomy (PECD), including the reduction in intervertebral disc height and the incidence of Modic changes. Overview of Literature: The anterior approach involves partial invasion of the intervertebral disc, with a reported reduction in intervertebral disc height after PECD...
April 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/29682329/active-discopathy-a-clinical-reality
#3
REVIEW
Margaux Boisson, Marie-Martine Lefèvre-Colau, François Rannou, Christelle Nguyen
In the late 1980s, the description by Modic and colleagues of elementary discovertebral changes detected on MRI (Modic classification) suggested for the first time a possible correlation between anatomical and clinical features in a subgroup of patients with non-specific chronic low back pain. Degenerative disc disease is frequent and usually asymptomatic, but Modic 1 changes in the vertebral endplates adjacent to a degenerated disc are associated with inflammatory-like chronic low back pain and low-grade local and systemic inflammation, which led to the concept of 'active discopathy'...
2018: RMD Open
https://www.readbyqxmd.com/read/29675672/low-virulence-bacterial-infections-in-cervical-intervertebral-discs-a-prospective-case-series
#4
Yilei Chen, Xianjun Wang, Xuyang Zhang, Hong Ren, Bao Huang, Jian Chen, Junhui Liu, Zhi Shan, Zhihai Zhu, Fengdong Zhao
STUDY DESIGN: A prospective cross-sectional case series study. OBJECTIVE: To investigate the prevalence of low virulence disc infection and its associations with characteristics of patients or discs in the cervical spine. BACKGROUND: Low virulence bacterial infections could be a possible cause of intervertebral disc degeneration and/or back pain. Controversies are continuing over whether these bacteria, predominantly Propionibacterium acnes (P...
April 19, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29669576/modic-changes-in-the-cervical-endplate-of-patients-suffering-from-cervical-spondylotic-myelopathy
#5
Pan Qiao, Tian-Tong Xu, Wen Zhang, Rong Tian
BACKGROUND: The distribution and related factors of Modic changes (MC) in the lumbar spine has been evaluated. In the present study, the MC in the cervical endplate of patients with cervical spondylotic myelopathy (CSM) was investigated. METHODS: A total of 6422 cervical endplates of 539 patients suffered from CSM (259 males and 280 females) with mean age of 46 ± 5.2 years. All patients underwent MRI scans and X-ray for evaluating the distribution of MC. The clinical information were recorded...
April 18, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29664923/effect-of-cartilaginous-endplates-on-extruded-disc-resorption-in-lumbar-disc-herniation
#6
Kenichi Kawaguchi, Katsumi Harimaya, Yoshihiro Matsumoto, Mitsumasa Hayashida, Seiji Okada, Keiichiro Iida, Go Kato, Kuniyoshi Tsuchiya, Toshio Doi, Yoshinao Oda, Yukihide Iwamoto, Yasuharu Nakashima
OBJECTIVE: The aim of this study was to investigate the clinicopathologic features of lumbar disc herniation (LDH) with endplate degeneration and the association between cartilaginous fragments and inflammatory response to the herniated disc. SUMMARY OF BACKGROUND DATA: LDH often involves hyaline cartilage fragments pulled from the vertebral endplates. Modic changes are closely associated with LDH that contains hyaline cartilage, and cartilaginous endplates seem to affect resorption of the herniated disc...
2018: PloS One
https://www.readbyqxmd.com/read/29661220/asymmetrical-degenerative-marrow-modic-changes-in-cervical-spine-prevalence-correlative-factors-and-surgical-outcomes
#7
Xianda Gao, Jia Li, Yiqing Shi, Shaoqing Li, Yong Shen
BACKGROUND: The current study aimed to discuss the prevalence and surgical outcomes of the asymmetrical Modic changes and identify its correlative factors by multivariate logistic regression analysis. METHODS: Two hundred seventy-eight patients with single-level Modic changes and nerve compression symptoms were reviewed retrospectively from January 2008 to January 2015. 1.5-T MRI was performed to determine the Modic changes. Multivariate logistic regression analysis was used to identify the correlative factors of asymmetrical Modic changes...
April 16, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29620898/analysis-of-advanced-glycation-endproducts-in-rat-tail-collagen-and-correlation-to-tendon-stiffening
#8
Tobias Jost, Alexander Zipprich, Marcus A Glomb
Methylglyoxal is a major 1,2-dicarbonyl compound in vivo and leads to nonenzymatic protein modifications, known as advanced glycation endproducts. Especially long-lived proteins like collagen are prone to changes of the mechanical or biological function, respectively, by accumulation of Maillard-derived modifications. Specifically, the resulting nonenzymatic cross-link structures in parallel to the natural maturation process of collagen fibrils lead to complications with age or during disease. A novel lysine-lysine amide cross-link derived from methylglyoxal, 2,15-diamino-8-methyl-9-oxo-7,10-diaza-1,16-hexadecanedioic acid, named MOLA, was synthesized and identified in vitro and in vivo...
April 18, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29615369/are-modic-changes-in-patients-with-chronic-low-back-pain-indicative-of-a-worse-clinical-course-10-years-of-follow-up
#9
L M Romero-Muñoz, A Barriga-Martín, A Segura-Fragoso, C Martín-González
OBJECTIVE: Establish the long-term (10 years) predictive value of Modic changes in the course of lumbar pain and the need for surgical treatment. MATERIAL AND METHOD: Observational longitudinal prospective cohort study. Comparison of progression at 10 years of 2 groups of patients with chronic lumbar pain: group A with Modic changes in MRI and group B with no Modic changes. EXCLUSION CRITERIA: neoplasia, inflammatory or infectious diseases, or previous surgery...
March 31, 2018: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/29572515/neuronal-differentiation-induces-snord115-expression-and-is-accompanied-by-post-transcriptional-changes-of-serotonin-receptor-2c-mrna
#10
Tomaž Bratkovič, Miha Modic, Germán Camargo Ortega, Micha Drukker, Boris Rogelj
The serotonin neurotransmitter system is widespread in the brain and implicated in modulation of neuronal responses to other neurotransmitters. Among 14 serotonin receptor subtypes, 5-HT2cR plays a pivotal role in controlling neuronal network excitability. Serotonergic activity conveyed through receptor 5-HT2cR is regulated post-transcriptionally via two mechanisms, alternative splicing and A-to-I RNA editing. Brain-specific small nucleolar RNA SNORD115 harbours a phylogenetically conserved 18-nucleotide antisense element with perfect complementarity to the region of 5ht2c primary transcript that undergoes post-transcriptional changes...
March 23, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29572167/radiological-analysis-on-kinematical-characteristics-of-modic-changes-based-on-lumbar-disc-degeneration-grade
#11
Fan Zhang, Hongli Wang, Haocheng Xu, Minghao Shao, Feizhou Lu, Jianyuan Jiang, Xiaosheng Ma, Xinlei Xia
No abstract text is available yet for this article.
March 20, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29550388/specialised-cleaning-associated-with-antimicrobial-coatings-for-reduction-of-hospital-acquired-infection-opinion-of-the-cost-action-network-amici-ca15114
#12
Suzanne S Dunne, Merja Ahonen, Martina Modic, Francy Rl Crijns, Minna M Keinänen-Toivola, Ruth Meinke, C William Keevil, Jim Gray, Nuala H O'Connell, Colum P Dunne
Recognized issues with poor hand hygiene compliance among healthcare workers, and reports of re-contamination of previously chemically disinfected surfaces through hand contact, emphasize need for novel hygiene methods in addition to those currently available. One such approach involves antimicrobial (nano)-coatings (AMC), whereby integrated active ingredients are responsible for elimination of microorganisms that come into contact with treated surfaces. While widely studied under laboratory conditions with promising results, studies under real life healthcare conditions are scarce...
March 14, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29543845/we-will-make-you-like-our-research-the-development-of-a-susceptibility-to-persuasion-scale
#13
David Modic, Ross Anderson, Jussi Palomäki
Psychological and other persuasive mechanisms across diverse contexts are well researched, with many studies of the effectiveness of specific persuasive techniques on distinct types of human behaviour. In the present paper, our specific interest lies in the development of a generalized modular psychometric tool to measure individuals' susceptibility to persuasion. The scale is constructed using items from previously developed and validated particulate scales established in the domains of social psychology and behavioural economics...
2018: PloS One
https://www.readbyqxmd.com/read/29538033/lumbar-osteophyte-avid-on-68ga-prostate-specific-membrane-antigen-pet-ct
#14
Mads Ryø Jochumsen, Michael Alle Madsen, Lise Gammelgaard, Kirsten Bouchelouche
A 75-year-old man with recently diagnosed high-risk prostate cancer was referred for primary staging with Ga-prostate-specific membrane antigen (PSMA) PET/CT. The scan revealed intense Ga-PSMA uptake in a lumbar osteophyte on the right side of level L2/L3, whereas several other spinal osteophytes showed no Ga-PSMA uptake. MRI findings in the L3 vertebra was consistent with a benign Modic type 1 lesion, but MRI showed no signs of malignancy in the osteophyte with high Ga-PMSA uptake. This case presents an osteophyte as an addition to the list of potential benign pitfalls to be aware of when interpreting Ga-PSMA PET/CT...
March 13, 2018: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29492717/the-global-spine-care-initiative-a-systematic-review-for-the-assessment-of-spine-related-complaints-in-populations-with-limited-resources-and-in-low-and-middle-income-communities
#15
REVIEW
Margareta Nordin, Kristi Randhawa, Paola Torres, Hainan Yu, Scott Haldeman, O'Dane Brady, Pierre Côté, Carlos Torres, Michael Modic, Rajani Mullerpatan, Christine Cedraschi, Roger Chou, Emre Acaroğlu, Eric L Hurwitz, Nadège Lemeunier, Jean Dudler, Anne Taylor-Vaisey, Erkin Sönmez
PURPOSE: The purpose of this systematic literature review was to develop recommendations for the assessment of spine-related complaints in medically underserved areas with limited resources. METHODS: We conducted a systematic review and best evidence synthesis of guidelines on the assessment of spine-related complaints. Independent reviewers critically appraised eligible guidelines using the Appraisal of Guidelines for Research and Evaluation-II criteria. Low risk of bias clinical practice guidelines was used to develop recommendations...
February 28, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29491718/prevalence-of-and-risk-factors-for-modic-change-in-patients-with-symptomatic-cervical-spondylosis-an-observational-study
#16
Jiangbo Bai, Kunlun Yu, Yaning Sun, Lingde Kong, Yong Shen
Background: The aim of this study was to assess the prevalence of cervical Modic change (MC) in patients with cervical spondylosis and to develop a better understanding of the possible risk factors for the prevalence of MC. Methods: Between January 2014 and April 2017, patients with cervical spondylosis were included in our study. All patients underwent magnetic resonance imaging (MRI) to evaluate the presence of MC. The MC was classified into three types according to the Modic classification...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29463258/the-association-between-subgroups-of-mri-findings-identified-with-latent-class-analysis-and-low-back-pain-in-40-year-old-danes
#17
Rikke K Jensen, Peter Kent, Tue S Jensen, Per Kjaer
BACKGROUND: Research into the clinical importance of spinal MRI findings in patients with low back pain (LBP) has primarily focused on single imaging findings, such as Modic changes or disc degeneration, and found only weak associations with the presence of pain. However, numerous MRI findings almost always co-exist in the lumbar spine and are often present at more than one lumbar level. It is possible that multiple MRI findings are more strongly associated with LBP than single MRI findings...
February 20, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29426732/predictive-value-of-modic-type-ii-changes-in-the-choice-of-surgical-treatment-of-lumbar-disc-herniation
#18
R Figa, C Morera-Dominguez
OBJECTIVE: To evaluate the predictive value of Modic typeII changes on nuclear magnetic resonance (NMR) prior to intervention by discectomy for lumbar disc herniation in patients with radicular symptoms. MATERIAL AND METHOD: Retrospective descriptive study of 190 patients (58.2% men and 41.8% women) with a mean age of 43.5 years, treated between December 2005 and January 2013. They were divided into group 1, single disc herniation (n=85), and group 2, with disc herniation and changes Modic typeII (n=80)...
February 6, 2018: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/29424676/a-multicenter-randomized-double-blind-dose-finding-study-of-condoliase-in-patients-with-lumbar-disc-herniation
#19
Yukihiro Matsuyama, Kazuhiro Chiba, Hisashi Iwata, Takayuki Seo, Yoshiaki Toyama
OBJECTIVE Chemonucleolysis with condoliase has the potential to be a new, less invasive therapeutic option for patients with lumbar disc herniation (LDH). The aim of the present study was to determine the most suitable therapeutic dose of condoliase. METHODS Patients between 20 and 70 years of age with unilateral leg pain, positive findings on the straight leg raise test, and LDH were recruited. All eligible patients were randomly assigned to receive condoliase (1.25, 2.5, or 5 U) or placebo. The primary end point was a change in the worst leg pain from preadministration (baseline) to week 13...
May 2018: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/29423885/intraosseous-basivertebral-nerve-ablation-for-the-treatment-of-chronic-low-back-pain-a-prospective-randomized-double-blind-sham-controlled-multi-center-study
#20
Jeffrey S Fischgrund, A Rhyne, J Franke, R Sasso, S Kitchel, H Bae, C Yeung, E Truumees, M Schaufele, P Yuan, P Vajkoczy, M DePalma, D G Anderson, L Thibodeau, B Meyer
PURPOSE: To evaluate the safety and efficacy of radiofrequency (RF) ablation of the basivertebral nerve (BVN) for the treatment of chronic low back pain (CLBP) in a Food and Drug Administration approved Investigational Device Exemption trial. The BVN has been shown to innervate endplate nociceptors which are thought to be a source of CLBP. METHODS: A total of 225 patients diagnosed with CLBP were randomized to either a sham (78 patients) or treatment (147 patients) intervention...
February 8, 2018: European Spine Journal
keyword
keyword
100437
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"