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https://www.readbyqxmd.com/read/28900744/structural-vertebral-endplate-nomenclature-and-etiology-a-study-by-the-issls-spinal-phenotype-focus-group
#1
Uruj Zehra, Cora Bow, Jeffrey C Lotz, Frances M K Williams, S Rajasekaran, Jaro Karppinen, Keith D K Luk, Michele C Battiê, Dino Samartzis
PURPOSE: Vertebral endplate abnormalities may be associated with disc degeneration and, perhaps, pain generation. However, consensus definitions for endplate findings on spine MRI do not exist, posing a challenge to compare findings between studies and ethnic groups. The following survey was created to characterize the variability among the global spine community regarding endplate structural findings with respect to nomenclature and etiology. METHODS: A working group within the International Society for the Study of the Lumbar Spine (ISSLS) Spinal Phenotype Focus Group was established to assess the endplate phenotype...
September 12, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28894387/modic-changes-of-the-cervical-spine-t1-slope-and-its-impact-on-axial-neck-pain
#2
Jia Li, Shuhui Qin, Yongqian Li, Yong Shen
BACKGROUND: The purpose of the research was to evaluate cervical sagittal parameters on magnetic resonance imaging (MRI) in patients with Modic changes and its impact on axial neck pain. METHODS: This study consisted of 266 consecutive asymptomatic or symptomatic patients with Modic changes, whose average age was 50.9±12.6 years from January 2015 to December 2016. Cervical sagittal parameters included sagittal alignment of the cervical spine (SACS), T1 slope, thoracic inlet angle (TIA), and neck tilt (NT)...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28891884/preceptorship-linguistic-upgrade
#3
Mary Beth Modic
No abstract text is available yet for this article.
September 2017: Journal for Nurses in Professional Development
https://www.readbyqxmd.com/read/28890222/identifying-subsets-of-patients-with-single-level-degenerative-disc-disease-for-lumbar-fusion-the-value-of-prognostic-tests-in-surgical-decision-making
#4
Victor E Staartjes, Pieter-Paul A Vergroesen, Dick J Zeilstra, Marc L Schröder
BACKGROUND CONTEXT: Fusion surgery for degenerative disc disease (DDD) has become a standard of care, albeit not without controversy. Outcomes are inconsistent and a superiority over conservative treatment is debatable. Proper patient selection is key to clinical success, and a comprehensive understanding of prognostic tests does not currently exist. PURPOSE: To investigate the value of prognostic tests and sociodemographic factors in predicting outcomes following lumbar fusion surgery for DDD...
September 7, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28884220/inflammatory-response-of-disc-cells-against-propionibacterium-acnes-depends-on-the-presence-of-lumbar-modic-changes
#5
Stefan Dudli, S Miller, S Demir-Deviren, J C Lotz
PURPOSE: Intervertebral disc with Propionibacterium acnes (P. acnes) is suggested to be an etiology of Modic type I changes in the adjacent bone marrow. However it is unknown if disc cells can respond to P. acnes and if bone marrow cells respond to bacterial and disc metabolites draining from infected discs. METHODS: Human disc cells (n = 10) were co-cultured with 10- and 100-fold excess of P. acnes over disc cells for 3 h and 24 h. Lipopolysaccharide was used as positive control...
September 7, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28874978/prevalence-patterns-and-genetic-association-analysis-of-modic-vertebral-endplate-changes
#6
Rishi Mugesh Kanna, Rajasekaran Shanmuganathan, Veera Ranjani Rajagopalan, Senthil Natesan, Raveendran Muthuraja, Kenneth Man Chee Cheung, Danny Chan, Patrick Yu Ping Kao, Anita Yee, Ajoy Prasad Shetty
STUDY DESIGN: A prospective genetic association study. PURPOSE: The etiology of Modic changes (MCs) is unclear. Recently, the role of genetic factors in the etiology of MCs has been evaluated. However, studies with a larger patient subset are lacking, and candidate genes involved in other disc degeneration phenotypes have not been evaluated. We studied the prevalence of MCs and genetic association of 41 candidate genes in a large Indian cohort. OVERVIEW OF LITERATURE: MCs are vertebral endplate signal changes predominantly observed in the lumbar spine...
August 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/28856839/comparison-of-cauliflower-insect-fungus-interactions-and-pesticides-for-cabbage-root-fly-control
#7
Jaka Razinger, Metka Žerjav, Meta Zemljič-Urbančič, Špela Modic, Matthias Lutz, Hans-Josef Schroers, Jürg Grunder, Simon Fellous, Gregor Urek
Cabbage root fly (Delia radicum L.) control represents a major challenge in brassica production, therefore different management strategies for its control were tested in conventionally managed open field cauliflower production. Strategies included treatments with low risk methods such as nitrogen lime, the insecticide spinosad and the Beauveria bassiana ATCC 74040 based biopesticide Naturalis. Their effects were compared with treatments based on non-formulated fungal species Metarhizium brunneum, B. bassiana, Clonostachys solani, Trichoderma atroviride, T...
August 30, 2017: Insect Science
https://www.readbyqxmd.com/read/28846710/apparent-diffusion-coefficient-maps-in-the-assessment-of-surgical-patients-with-lumbar-spine-degeneration
#8
Evgenii Belykh, Andrey A Kalinin, Arpan A Patel, Eric J Miller, Michael A Bohl, Ivan A Stepanov, Liudmila A Bardonova, Talgat Kerimbaev, Anton O Asantsev, Morgan B Giers, Mark C Preul, Vadim A Byvaltsev
PURPOSE: To assess the utility of apparent diffusion coefficient (ADC) maps for the assessment of patients with advanced degenerative lumbar spine disease and describe characteristic features of ADC maps in various degenerative lumbar spinal conditions. METHODS: T1-weighted, T2-weighted and diffusion weighted (DWI) MR images of 100 consecutive patients admitted to the spinal surgery service were assessed. ADC maps were generated from DWI images using Osyrix software...
2017: PloS One
https://www.readbyqxmd.com/read/28816975/incidence-and-risk-factors-of-posterior-cage-migration-following-decompression-and-instrumented-fusion-for-degenerative-lumbar-disorders
#9
Hua Li, Hui Wang, Yanbo Zhu, Wenyuan Ding, Qian Wang
The aim of this study was to explore the incidence and risk factors for posterior cage migration (PCM) following decompression and instrumented fusion for degenerative lumbar disorders, and hope to provide references in decision making and surgical planning for spine surgeons.By retrieving the medical records from January 2011 to December 2015, 286 patients were retrospectively reviewed. According to the occurrence of PCM, patients were divided into 2 groups: PCM group and non-PCM (N-PCM). To investigate risk values for PCM, 3 categorized factors were analyzed statistically: patient characteristics: age, sex, body mass index, bone mineral density, duration of disease, diagnosis, comorbidity, smoke; surgical variables: surgery time, blood loss, surgical strategy, cage morphology, cage size, surgical segment, fusion number, source of bone graft, surgeon experience; radiographic parameters: preoperative lumbar lordosis, correction of lumbar lordosis, preoperative lumbar mobility, preoperative intervertebral height, change of intervertebral height, Modic changes, paraspinal muscle degeneration...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28816947/kinematic-analysis-of-the-relationship-between-modic-changes-and-sagittal-balance-parameters-in-the-cervical-spine
#10
Zikun Ma, Peng Liu, Jingpei Liu, Jianhui Mou, Zhaolin Wang, Dong Sun, Jie Cheng, Dengwei Zhang, Jianlin Xiao
The aim of this study is to investigate the relationship between the Modic changes (MCs) and sagittal parameters of the cervical spine.We conducted a retrospective review of 100 outpatients with magnetic resonance imaging (MRI) scans of the cervical spine (50 male and 50 female). MRI parameters were measured, including neck tilt, T1 slope (T1 ), thoracic inlet angle (TIA), and cervical lordosis (CL: Cobb C2-7). Patients were divided into 4 groups according to the presence or absence of MC and T1s, respectively: MC(+) and MC(-) groups, as well as H-T1s (T1s ≥25°) and L-T1s subgroups (T1s <25°)...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28808792/using-natural-language-processing-of-free-text-radiology-reports-to-identify-type-1-modic-endplate-changes
#11
Hannu T Huhdanpaa, W Katherine Tan, Sean D Rundell, Pradeep Suri, Falgun H Chokshi, Bryan A Comstock, Patrick J Heagerty, Kathryn T James, Andrew L Avins, Srdjan S Nedeljkovic, David R Nerenz, David F Kallmes, Patrick H Luetmer, Karen J Sherman, Nancy L Organ, Brent Griffith, Curtis P Langlotz, David Carrell, Saeed Hassanpour, Jeffrey G Jarvik
Electronic medical record (EMR) systems provide easy access to radiology reports and offer great potential to support quality improvement efforts and clinical research. Harnessing the full potential of the EMR requires scalable approaches such as natural language processing (NLP) to convert text into variables used for evaluation or analysis. Our goal was to determine the feasibility of using NLP to identify patients with Type 1 Modic endplate changes using clinical reports of magnetic resonance (MR) imaging examinations of the spine...
August 14, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/28802716/presence-of-modic-type-1-change-increases-risk-of-postoperative-pyogenic-discitis-following-decompression-surgery-for-lumbar-canal-stenosis
#12
Ken Ninomiya, Nobuyuki Fujita, Naobumi Hosogane, Tomohiro Hikata, Kota Watanabe, Osahiko Tsuji, Narihito Nagoshi, Mitsuru Yagi, Shinjiro Kaneko, Yasuyuki Fukui, Takahiro Koyanagi, Tateru Shiraishi, Takashi Tsuji, Masaya Nakamura, Morio Matsumoto, Ken Ishii
STUDY DESIGN: Multicenter retrospective study. BACKGROUND: Postoperative surgical site infection is one of the most serious complications following spine surgery. Previous studies do not appear to have investigated pyogenic discitis following lumbar laminectomy without discectomy. This study aimed to identify risk factors for postoperative pyogenic discitis following lumbar decompression surgery. METHODS: We examined data from 2721 patients undergoing lumbar laminectomy without discectomy in five hospitals from April 2007 to March 2012...
August 10, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28769985/long-term-course-to-lumbar-disc-resorption-patients-and-predictive-factors-associated-with-disc-resorption
#13
Jinho Lee, Joowon Kim, Joon-Shik Shin, Yoon Jae Lee, Me-Riong Kim, Seon-Yeong Jeong, Young-Jun Choi, Tae Kyung Yoon, Byung-Heon Moon, Su-Bin Yoo, Jungsoo Hong, In-Hyuk Ha
The long-term course to lumbar intervertebral disc herniation (LDH) patients receiving integrative Korean medicine treatment and predictive factors associated with disc resorption were investigated. LDH patients who received integrative Korean medicine treatment from February 2012 to December 2015 and were registered in the "longitudinal project for LDH on MRI" were included. Disc resorption amount was measured 3-dimensionally with disc degeneration and modic change levels on baseline and follow-up MRIs. Patient characteristics, Korean medicine use, pain, symptom recurrence, and satisfaction were assessed through medical records and phone surveys...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28769586/characteristics-of-modic-changes-in-cervical-kyphosis-and-their-association-with-axial-neck-pain
#14
Yonghui An, Jia Li, Yongqian Li, Yong Shen
BACKGROUND: The purpose of this study was to evaluate characteristics of Modic changes in cervical kyphosis (CK) and their association with axial neck pain. METHODS: Study participants included 286 asymptomatic or symptomatic patients with CK (mean age = 54.2 ± 12.2 years) who were consecutively enrolled from March 2009 to October 2015. Clinical and radiographic evaluations were performed at a university outpatient department. CK was classified as global type, reverse sigmoid type, or sigmoid type...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28767629/modic-changes-and-disc-degeneration-of-non-fused-segments-27-to-45-years-after-harrington-instrumentation-for-adolescent-idiopathic-scoliosis-comparison-to-healthy-controls
#15
Tsutomu Akazawa, Toshiaki Kotani, Tsuyoshi Sakuma, Shohei Minami, Sumihisa Orita, Kazuhide Inage, Kazuki Fujimoto, Yasuhiro Shiga, Yoshiaki Torii, Tasuku Umehara, Masahiro Iinuma, Shingo Kuroya, Hisateru Niki, Seiji Ohtori, Kazuhisa Takahashi
STUDY DESIGN: A case control study. OBJECTIVE: To investigate the long-term prevalence of the Modic changes and disc degeneration in the non-fused segments of the surgically treated adolescent idiopathic scoliosis (AIS) patients and compare with age- and sex-matched healthy controls. SUMMARY OF BACKGROUND DATA: No studies have looked at the association between Modic changes and low back pain in patients who underwent AIS surgery many years ago...
August 1, 2017: Spine
https://www.readbyqxmd.com/read/28767621/the-ute-disc-sign-on-mri-a-novel-imaging-biomarker-associated-with-degenerative-spine-changes-low-back-pain-and-disability
#16
Henry Pang, Cora Bow, Jason Pui Yin Cheung, Uruj Zehra, Arijitt Borthakur, Jaro Karppinen, Nozomu Inoue, Hai-Qiang Wang, Keith D K Luk, Kenneth M C Cheung, Dino Samartzis
STUDY DESIGN: Cross-sectional. OBJECTIVE: To assess the distribution of the ultra-short time-to-echo (UTE) Disc Sign (UDS).and its association with disc degeneration, other MRI phenotypes, pain and disability profiles. SUMMARY OF BACKGROUND DATA: Disc degeneration has been conventionally assessed by T2-weighted (T2W) signal intensity on MRI; however, its clinical utility has been questionable. UTE MRI assesses short T2 components. The authors have identified a new imaging biomarker on UTE - the UDS...
August 1, 2017: Spine
https://www.readbyqxmd.com/read/28765523/robust-spin-correlations-at-high-magnetic-fields-in-the-harmonic-honeycomb-iridates
#17
K A Modic, B J Ramshaw, J B Betts, Nicholas P Breznay, James G Analytis, Ross D McDonald, Arkady Shekhter
The complex antiferromagnetic orders observed in the honeycomb iridates are a double-edged sword in the search for a quantum spin-liquid: both attesting that the magnetic interactions provide many of the necessary ingredients, while simultaneously impeding access. Focus has naturally been drawn to the unusual magnetic orders that hint at the underlying spin correlations. However, the study of any particular broken symmetry state generally provides little clue about the possibility of other nearby ground states...
August 1, 2017: Nature Communications
https://www.readbyqxmd.com/read/28745679/-low-back-pain-and-modic-changes
#18
E L Sokov, L E Kornilova, A I Nesterov
Modic changes (MCh) are pathological changes in the bone marrow and the endplates of adjacent vertebrae characterized by bone marrow edema, fatty degeneration or osteosclerosis that are revealed by high-power field magnetic resonance imaging (MRI). The dominant disease pattern is a persistent back pain syndrome with varying intensity. It leads to difficulties in the interpretation of clinical data, evaluation of MRI data and treatment. The article presents a modern conception of the pathogenesis, classification, clinical implications and treatment of MCh based on national and foreign sources as well and the author's view on the osteogenic mechanism of the pathogenesis and treatment of MCh using intraosseous blockades...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28704907/effect-of-modic-changes-in-cervical-degenerative-disease
#19
Kyung Tag Kang, Dong Wuk Son, Oik Kwon, Su Hun Lee, Jong Uk Hwang, Dong Ha Kim, Jun Seok Lee, Geun Sung Song
OBJECTIVE: Modic changes are signal intensity changes in adjacent vertebral bone marrow on magnetic resonance imaging. Few studies have investigated these changes with regard to the cervical spine. In this study, we investigated the associations between cervical degenerative disease and Modic changes. METHODS: We conducted a retrospective collection of radiological data in patients with neck pain at Pusan National University Yangsan Hospital from January 2010 to December 2014...
June 2017: Korean Journal of Spine
https://www.readbyqxmd.com/read/28683036/the-pivotal-preceptor-promoter-of-civility
#20
Mary Beth Modic
No abstract text is available yet for this article.
July 2017: Journal for Nurses in Professional Development
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