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Maheer M Masood, Massimiliano Di Giosia, Trevor G Hackman
BACKGROUND: First bite syndrome is a well-recognized complication of parapharyngeal space surgery. There are no reported cases of protracted first bite syndrome and subsequent diagnosis of a primary squamous cell carcinoma (SCC) of the parotid. METHODS: We present the case of a 73-year-old man with no surgical history and 9 years of first bite syndrome who was ultimately diagnosed with a primary SCC of the parotid. Diagnostic workup, including MRI and biopsy, along with oncologic treatment, were performed...
June 21, 2018: Head & Neck
Fatemeh Rajati, Hosein Ashtarian, Nader Salari, Masood Ghanbari, Zahra Naghibifar, Seyed Younes Hosseini
BACKGROUND: Physically disabled people experience more restrictions in social activities than healthy people, which are associated with lower level of well-being and poor quality of life (QoL). STUDY DESIGN: A cross-sectional study was conducted. METHODS: This study was investigated on among 302 eligible physically disabled people. The predictive role of the demographics and clinical characteristics, anxiety and depression, physical activity, and self-efficacy on the 36-Item Short Form Health Survey (SF-36) was examined...
2018: Journal of Education and Health Promotion
Majid Asadi-Ghalehni, Mohamad Javad Rasaee, Nabiollah Namvar Asl, Masood Khosravani, Masoumeh Rajabibazl, Saeed Khalili, Helmout Modjtahedi, Esmaeil Sadroddiny
Over expression of the epidermal growth factor receptor (EGFR) in many human epithelial tumors has been correlated with disease progression and poor prognosis. EGFR-inhibiting immunotherapy has already been introduced in cancer therapy. Peptide displaying phage particles in eukaryotic hosts can behave as antigen carriers, able to activate the innate immune system and to elicit adaptive immunity. Herein, the M13-pAK8-VIII phagemid plasmid was engineered to contain the sequences for an EGFR mimotope along with the L2 extracellular domain of EGFR (EM-L2) which would produce the final peptide-phage vaccine...
June 2018: Iranian Journal of Allergy, Asthma, and Immunology
Nazilla Khanlou, Anne Mantini, Attia Khan, Katie Degendorfer, Masood Zangeneh
Protection of privacy of information for young adults with developmental disabilities and their families is essential to promote quality of life, well-being, empowerment, and inclusion. Despite this, the young adults' information privacy rights are increasingly at risk. This paper provides a scoping review, applying Arksey and O'Malley's (2005) approach, of all published peer-reviewed journal articles and gray literature to examine the barriers and facilitators in utilization of legislation that protects the collection, use, disclosure, and access of personal information in Canada...
2018: International Journal of Mental Health and Addiction
Douglas R Farquhar, Rounak B Rawal, Maheer M Masood, Wade G McClain, Lauren A Kilpatrick, Austin S Rose, Carlton J Zdanski
Thyroglossal duct cysts (TGDC) excisions was traditionally an inpatient procedure, but there has been a recent trend towards outpatient surgery. Our aim is to use the NSQIP-P to examine overall thirty-day outcomes for TGDC excision, and to determine whether they are affected by admission status and surgeon specialty. We assessed the demographics, preoperative risk factors, and negative outcomes of admitted and same-day surgery TGDC patients, and TGDC patients of surgeons with different training. Outcomes were thirty-day rates for readmissions, reoperations, unplanned reintubations, major complications, and minor complications...
June 14, 2018: Clinical Otolaryngology
Muhammad Rashid Ahmed, Masood Ahmed Shaikh, Syed Hafiz Imran Ul Haq, Shakila Nazir
Objective: Selective degeneration of dopaminergic neurons is the pathological hallmark of Parkinson disease (PD). Enhanced oxidative stress, lipid peroxidation and susceptibility of dopaminergic neurons to apoptotic cellular death are the leading pathogenetic mechanisms. Chrysin is an active flavonoid. Its neuroprotective effects have been reported. This study examined the neuroprotective effects of chrysin in ameliorating the dopaminergic neuronal degeneration and motor behavioral changes in rotenone model of PD...
May 2018: International Journal of Health Sciences
Rashid Jooma, Masood Ali Shaikh
The Karachi city's Road Traffic Injury Research and Prevention Center (RTIRPC), collects Road Traffic Crash (RTC) data on injuries and fatalities from three major public and private hospitals' emergency departments. In the year 2015, 1021 deaths were recorded; with 871 (85.3%) deaths in males. Cumulatively, 286 (28.0%) deaths were recorded in the 21-30year age group, and for 198 (19.4%) RTC fatal victims, the primary vehicle involved was motorbike. Highest number of fatalities were recorded in the month of January i...
May 2018: JPMA. the Journal of the Pakistan Medical Association
Obada Hasan, Shah Fahad, Masood Ume, Haroon Rashid
BACKGROUND: Lateral malleolus fracture can occur alone or is associated with the fracture of the medial malleolus leading to ankle instability. Treatment is aimed to achieve anatomical reduction and ensure stability. Compared to non-locking plate locking plate provide stable construct and compromise bone vascularity less. However, there is increase wound complication with locking plates than non-locking plates. PHILOS plate combines the principles of fixation with a conventional plate with those of locking screws...
June 5, 2018: International Journal of Surgery
Rashid Masood, Tanveer Hussain, Mohsen Miraftab, Zulfiqar Ali Raza, Azeem Ullah, Tanzeel Areeb, Muhammad Umar, Rabia Riaz
OBJECTIVE: Tri-component antibacterial psyllium-alginate-chitosan fibres were developed and their properties were studied with reference to their application in health-care. METHOD: Psyllium was co-extruded with sodium alginate as a carrier into a coagulation bath containing calcium chloride and hydrolysed chitosan. Different concentrations of the hydrolysed chitosan were used and an in vitro assessment of antibacterial activity of the produced fibres was carried out against the known pathogens of Staphylococcus aureus and Escherichia coli...
June 2, 2018: Journal of Wound Care
David Coggon, Georgia Ntani, Keith T Palmer, Vanda E Felli, Florencia Harari, Leonardo A Quintana, Sarah A Felknor, Marianela Rojas, Anna Cattrell, Sergio Vargas-Prada, Matteo Bonzini, Eleni Solidaki, Eda Merisalu, Rima R Habib, Farideh Sadeghian, M Masood Kadir, Sudath Sp Warnakulasuriya, Ko Matsudaira, Busisiwe Nyantumbu-Mkhize, Helen L Kelsall, Helen Harcombe
BACKGROUND: Wide international variation in the prevalence of disabling low back pain (LBP) among working populations is not explained by known risk factors. It would be useful to know whether the drivers of this variation are specific to the spine or factors that predispose to musculoskeletal pain more generally. METHODS: Baseline information about musculoskeletal pain and risk factors was elicited from 11,710 participants aged 20-59 years, who were sampled from 45 occupational groups in 18 countries...
June 8, 2018: European Journal of Pain: EJP
Masood Sadaat, Sekwon Jang
BACKGROUND: Hemophagocytic Lymphohistiocytosis (HLH), a rare but potentially fatal syndrome of immune hyperactivation, may be an under-recognized immune-related adverse event (irAE). Unlike other irAEs, HLH triggered by immune checkpoint blockade is not well described; no particular diagnostic guidelines and treatment regimens exist. The HLH-2004 criteria remain as the common diagnostic guide. For the treatment of HLH, various combinations of chemotherapeutic, immunosuppressive and glucocorticoid agents are used...
June 5, 2018: Journal for Immunotherapy of Cancer
Azadeh Bashiri, Leila Shahmoradi, Hamid Beigy, Behrouz A Savareh, Masood Nosratabadi, Sharareh R N Kalhori, Marjan Ghazisaeedi
Aim: Quantitative EEG gives valuable information in the clinical evaluation of psychological disorders. The purpose of the present study is to identify the most prominent features of quantitative electroencephalography (QEEG) that affect attention and response control parameters in children with attention deficit hyperactivity disorder. Methods: The QEEG features and the Integrated Visual and Auditory-Continuous Performance Test ( IVA-CPT) of 95 attention deficit hyperactivity disorder subjects were preprocessed by Independent Evaluation Criterion for Binary Classification...
June 2018: Future Science OA
Christina Fitzmaurice, Tomi F Akinyemiju, Faris Hasan Al Lami, Tahiya Alam, Reza Alizadeh-Navaei, Christine Allen, Ubai Alsharif, Nelson Alvis-Guzman, Erfan Amini, Benjamin O Anderson, Olatunde Aremu, Al Artaman, Solomon Weldegebreal Asgedom, Reza Assadi, Tesfay Mehari Atey, Leticia Avila-Burgos, Ashish Awasthi, Huda Omer Ba Saleem, Aleksandra Barac, James R Bennett, Isabela M Bensenor, Nickhill Bhakta, Hermann Brenner, Lucero Cahuana-Hurtado, Carlos A Castañeda-Orjuela, Ferrán Catalá-López, Jee-Young Jasmine Choi, Devasahayam Jesudas Christopher, Sheng-Chia Chung, Maria Paula Curado, Lalit Dandona, Rakhi Dandona, José das Neves, Subhojit Dey, Samath D Dharmaratne, David Teye Doku, Tim R Driscoll, Manisha Dubey, Hedyeh Ebrahimi, Dumessa Edessa, Ziad El-Khatib, Aman Yesuf Endries, Florian Fischer, Lisa M Force, Kyle J Foreman, Solomon Weldemariam Gebrehiwot, Sameer Vali Gopalani, Giuseppe Grosso, Rahul Gupta, Bishal Gyawali, Randah Ribhi Hamadeh, Samer Hamidi, James Harvey, Hamid Yimam Hassen, Roderick J Hay, Simon I Hay, Behzad Heibati, Molla Kahssay Hiluf, Nobuyuki Horita, H Dean Hosgood, Olayinka S Ilesanmi, Kaire Innos, Farhad Islami, Mihajlo B Jakovljevic, Sarah Charlotte Johnson, Jost B Jonas, Amir Kasaeian, Tesfaye Dessale Kassa, Yousef Saleh Khader, Ejaz Ahmad Khan, Gulfaraz Khan, Young-Ho Khang, Mohammad Hossein Khosravi, Jagdish Khubchandani, Jacek A Kopec, G Anil Kumar, Michael Kutz, Deepesh Pravinkumar Lad, Alessandra Lafranconi, Qing Lan, Yirga Legesse, James Leigh, Shai Linn, Raimundas Lunevicius, Azeem Majeed, Reza Malekzadeh, Deborah Carvalho Malta, Lorenzo G Mantovani, Brian J McMahon, Toni Meier, Yohannes Adama Melaku, Mulugeta Melku, Peter Memiah, Walter Mendoza, Tuomo J Meretoja, Haftay Berhane Mezgebe, Ted R Miller, Shafiu Mohammed, Ali H Mokdad, Mahmood Moosazadeh, Paula Moraga, Seyyed Meysam Mousavi, Vinay Nangia, Cuong Tat Nguyen, Vuong Minh Nong, Felix Akpojene Ogbo, Andrew Toyin Olagunju, Mahesh Pa, Eun-Kee Park, Tejas Patel, David M Pereira, Farhad Pishgar, Maarten J Postma, Farshad Pourmalek, Mostafa Qorbani, Anwar Rafay, Salman Rawaf, David Laith Rawaf, Gholamreza Roshandel, Saeid Safiri, Hamideh Salimzadeh, Juan Ramon Sanabria, Milena M Santric Milicevic, Benn Sartorius, Maheswar Satpathy, Sadaf G Sepanlou, Katya Anne Shackelford, Masood Ali Shaikh, Mahdi Sharif-Alhoseini, Jun She, Min-Jeong Shin, Ivy Shiue, Mark G Shrime, Abiy Hiruye Sinke, Mekonnen Sisay, Amber Sligar, Muawiyyah Babale Sufiyan, Bryan L Sykes, Rafael Tabarés-Seisdedos, Gizachew Assefa Tessema, Roman Topor-Madry, Tung Thanh Tran, Bach Xuan Tran, Kingsley Nnanna Ukwaja, Vasiliy Victorovich Vlassov, Stein Emil Vollset, Elisabete Weiderpass, Hywel C Williams, Nigus Bililign Yimer, Naohiro Yonemoto, Mustafa Z Younis, Christopher J L Murray, Mohsen Naghavi
Importance: The increasing burden due to cancer and other noncommunicable diseases poses a threat to human development, which has resulted in global political commitments reflected in the Sustainable Development Goals as well as the World Health Organization (WHO) Global Action Plan on Non-Communicable Diseases. To determine if these commitments have resulted in improved cancer control, quantitative assessments of the cancer burden are required. Objective: To assess the burden for 29 cancer groups over time to provide a framework for policy discussion, resource allocation, and research focus...
June 2, 2018: JAMA Oncology
Masood Ali Shaikh
This case study demonstrates the use of population based, spatial analysis of public health indices in Pakistan. The data for this study were obtained from the Pakistan Bureau of Statistics website. Using district level data, for the spatial analysis of having being sick or injured, and their correlates in the under-five year old children. Percent under 5 year children, who either fell sick or injured during the past two-weeks by district, was used as an outcome variable in the final spatial regression model...
April 2018: JPMA. the Journal of the Pakistan Medical Association
Muhammad Umar, Tahir Masood, Mazhar Badshah
OBJECTIVE: To determine the effect of botulinum toxin A and task-specific training on upper limb function in post-stroke focal dystonia patients. METHODS: A randomised control trial was conducted at hospitals in Rawalpindi and Islamabad, Pakistan, from October 2015 to September 2016. The subjects were recruited using non-probability purposive sampling and were divided equally into control and experimental groups by sealed envelope method. The experimental group received botulinum toxin A followed by task-specific training, while the control group received only task-specific training for 8 weeks...
April 2018: JPMA. the Journal of the Pakistan Medical Association
Najat Masood, Normala Halimoon, Ahmad Zaharin Aris, Mohamad Pauzi Zakaria, Vahab Vaezzadeh, Sami M Magam, Shuhaimi Mustafa, Masni Mohd Ali, Mehrzad Keshavarzifard, Sadeq Abdullah Abdo Alkhadher, Chui Wei Bong, Murad Ali Alsalahi
Rapid increase in industrialization and urbanization in the west coast of Peninsular Malaysia has led to the intense release of petroleum and products of petroleum into the environment. Surface sediment samples were collected from the Selangor River in the west coast of Peninsular Malaysia during four climatic seasons and analyzed for PAHs and biomarkers (hopanes). Sediments were soxhlet extracted and further purified and fractionated through first and second step column chromatography. A gas chromatography-mass spectrometry (GC-MS) was used for analysis of PAHs and hopanes fractions...
May 25, 2018: Environmental Geochemistry and Health
Maheer M Masood, Douglas R Farquhar, Christopher Biancaniello, Trevor G Hackman
Importance: Mucus plugging after tracheostomy is a preventable cause of respiratory distress. Implementation of standardized tracheostomy care guidelines may reduce the occurrence of fatal respiratory compromise. Objective: To determine the effect of implementing and reinforcing a standardized tracheostomy care protocol on the occurrence of acute life-threatening respiratory events. Design, Setting, and Participants: Retrospective cohort study of adult patients who received a tracheostomy between May 2014 and August 2016 at a tertiary care center...
May 24, 2018: JAMA Otolaryngology—Head & Neck Surgery
Iram Saleem, Samina Masood, Derek Smith, Wei-Kan Chu
This research project has major applications in the healthcare and biomedical industries. Bacteria reside in human bodies and play an integral role in the mechanism of life. However, their excessive growth or the invasion of similar agents can be dangerous and may cause fatal or incurable diseases. On the other hand, increased exposure to electromagnetic radiation and its impact on health and safety is a common concern to medical science. Some nanostructure materials have interesting properties regarding facilitating or impeding cell growth...
May 24, 2018: MicrobiologyOpen
Shailesh Kumar Singh, Syed Masood Husain
Superoxide (O2*-) generation in biological systems is achieved through some of the most complex enzymatic systems. Of these, only the xanthine/xanthine oxidase has been used for in vitro biochemical studies. However, it suffers from limitations such as, lack of suitable heterologous expression system for xanthine oxidase and the irreversible consumption along with low solubility of xanthine under physiological conditions. Here, we report a redox-based, enzyme-catalyzed system where autoxidation of hydroquinone to quinone via semiquinone results in superoxide generation...
May 23, 2018: Chembiochem: a European Journal of Chemical Biology
Badroddin Najmi, Zahra Heidari, Awat Feizi, Silva Hovsepian, Farzaneh Momeni, Seied Mohammad Masood Azhar
BACKGROUND/OBJECTIVE: We aimed at assessing the parenting stress levels among mothers of children with different disabilities and its association with various mothers' psychological characteristics. METHODS: In this cross-sectional study, 302 mothers of 6-12years old children suffering from sensory motor mental, chronic physical and psychological disabilities were enrolled. Parenting stress, coping stratyles, marital satisfaction and psychological problems of mothers were assessed using validated questionnaires...
June 2018: Archives of Psychiatric Nursing
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