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Pipeline embolization device

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https://www.readbyqxmd.com/read/29765391/abciximab-reopro-dosing-strategy-for-the-management-of-acute-intraprocedural-thromboembolic-complications-during-pipeline-flow-diversion-treatment-of-intracranial-aneurysms
#1
Li-Mei Lin, Bowen Jiang, Jessica K Campos, Narlin B Beaty, Matthew T Bender, Rafael J Tamargo, Judy Huang, Geoffrey P Colby, Alexander L Coon
Background: Flow diversion with the Pipeline embolization device (PED) is an effective neuro-endovascular method and increasingly accepted for the treatment of cerebral aneurysms. Acute in situ thrombosis is a known complication of PED procedures. There is limited experience in the flow diversion literature on the use of abciximab (ReoPro) for the management of acute thrombus formation in PED cases. Methods: Data were collected retrospectively on patients who received intra-arterial (IA) ReoPro with or without subsequent intravenous (IV) infusion during PED flow diversion treatment of intracranial aneurysms...
April 2018: Interventional Neurology
https://www.readbyqxmd.com/read/29754516/acute-retinal-hemorrhage-after-pipeline-embolization-device-placement-for-treatment-of-ophthalmic-segment-aneurysm-a-case-report
#2
Nimer Adeeb, Justin Moore, Christoph J Griessenauer, Raghav Gupta, Ahad A Fazelat, Christopher S Ogilvy, Ajith J Thomas
Introduction Ophthalmic segment aneurysms may present with visual symptoms due to direct compression of the optic nerve. Treatment of these aneurysms with the Pipeline embolization device (PED) often results in visual improvement. Flow diversion, however, has also been associated with occlusion of the ophthalmic artery and visual deficits in a small subset of cases. Case report A 49-year-old Caucasian female presented with subarachnoid hemorrhage due to a ruptured anterior communicating artery aneurysm. On follow-up imaging, the patient was found to have a right asymptomatic ophthalmic segment aneurysm...
January 1, 2018: Interventional Neuroradiology
https://www.readbyqxmd.com/read/29726768/pipeline-embolization-of-posterior-circulation-aneurysms-a-multicenter-study-of-131-aneurysms
#3
Christoph J Griessenauer, Christopher S Ogilvy, Nimer Adeeb, Adam A Dmytriw, Paul M Foreman, Hussain Shallwani, Nicola Limbucci, Salvatore Mangiafico, Ashish Kumar, Caterina Michelozzi, Timo Krings, Vitor Mendes Pereira, Charles C Matouk, Mark R Harrigan, Hakeem J Shakir, Adnan H Siddiqui, Elad I Levy, Leonardo Renieri, Thomas R Marotta, Christophe Cognard, Ajith J Thomas
OBJECTIVE Flow diversion for posterior circulation aneurysms performed using the Pipeline embolization device (PED) constitutes an increasingly common off-label use for otherwise untreatable aneurysms. The safety and efficacy of this treatment modality has not been assessed in a multicenter study. METHODS A retrospective review of prospectively maintained databases at 8 academic institutions was performed for the years 2009 to 2016 to identify patients with posterior circulation aneurysms treated with PED placement...
May 4, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29726765/aneurysms-with-persistent-filling-after-failed-treatment-with-the-pipeline-embolization-device
#4
Badih Daou, Elias Atallah, Nohra Chalouhi, Robert M Starke, Jeffrey Oliver, Maria Montano, Pascal Jabbour, Robert H Rosenwasser, Stavropoula I Tjoumakaris
OBJECTIVE The Pipeline embolization device (PED) has become a valuable tool in the treatment of cerebral aneurysms. Although failures with PED treatment have been reported, the characteristics and course of these aneurysms remain a topic of uncertainty. METHODS Electronic medical records and imaging studies were reviewed for all patients treated with the PED between July 2010 and March 2015 to identify characteristics of patients and aneurysms with residual filling after PED treatment. RESULTS Of 316 cases treated at a single institution, 281 patients had a long-term follow-up...
May 4, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29719554/pipeline-flex-embolization-of-flow-related-aneurysms-associated-with-arteriovenous-malformations-a-case-report
#5
Narlin B Beaty, Jessica K Campos, Geoffrey P Colby, Li-Mei Lin, Matthew T Bender, Risheng Xu, Alexander L Coon
Background: An estimated 0.1% of the population harbors brain arteriovenous malformations (AVMs). Diagnosis and workup of AVMs include thorough evaluation for characterization of AVM angioarchitecture and careful assessment for concomitant aneurysms. The presence of coexisting aneurysms is associated with an increased risk of intracranial hemorrhage, with a published risk of 7% per year compared to patients with AVMs alone with a risk of 3%. Comprehensive AVM management requires recognition of concomitant aneurysms and prioritizes treatment strategies to mitigate the aggregate risk of intracranial hemorrhage associated with AVM rupture in patients with coexisting aneurysms...
April 2018: Interventional Neurology
https://www.readbyqxmd.com/read/29719553/47-consecutive-cases-of-pipeline-flex-flow-diversion-utilizing-a-novel-large-bore-intracranial-intermediate-catheter-nuances-and-institutional-experience-with-the-syphontrak
#6
Li-Mei Lin, Bowen Jiang, Matthew T Bender, Erick M Westbroek, Jessica K Campos, Rafael J Tamargo, Judy Huang, Alexander L Coon, Geoffrey P Colby
Background: The increasing complexity of modern neurointerventions has necessitated a shift in intracranial access techniques towards more robust distal support platforms. Here we present our experience with the Syphontrak Support Catheter (Codman Neuro, Raynham, MA, USA) in the triaxial platform for the implantation of the second-generation Pipeline Flex embolization device (PED Flex; Medtronic Neurovascular, Irvine, CA, USA). Methods: We retrospectively identified patients who underwent PED Flex treatment utilizing the Syphontrak at a single institution...
April 2018: Interventional Neurology
https://www.readbyqxmd.com/read/29710055/tied-pipeline-a-case-of-rare-complication
#7
Shigeru Miyachi, Hiroyuki Ohnishi, Ryo Hiramatsu, Ryokichi Yagi, Toshihiko Kuroiwa
A 48-year-old female with a symptomatic giant carotid cavernous aneurysm underwent endovascular treatment with multiple Pipeline Flex embolic devices (PED). The delivery catheter had to take a complicated course of multiple turns to cross the aneurysm, and its loop was tied in the aneurysm. When the catheter was to be withdrawn, it was apparent that the tied catheter had made a tight knot that bound the tail of the previous PED together. We successfully retrieved all of the system including the tied PED, and we used telescoping stents with five PEDs in the next operation...
May 1, 2018: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/29698879/use-of-pipeline%C3%A2-embolization-device-for-the-treatment-of-traumatic-intracranial-pseudoaneurysms-case-series-and-review-of-cases-from-literature
#8
Mairaj T Sami, Domenico A Gattozzi, Hesham M Soliman, Alan R Reeves, Christopher J Moran, Paul J Camarata, Koji C Ebersole
OBJECTIVE: Intracranial traumatic pseudoaneurysms (PSA) are a rare but dangerous subtype of cerebral aneurysm. Reports documenting use of flow-diverting stents to treat traumatic intracranial PSAs are few and lack long-term follow-up. To our knowledge, this is the largest case-series to date demonstrating use of Pipeline Endovascular Device (PED) for traumatic intracranial PSAs. PATIENTS AND METHODS: Retrospective review of 8 intracranial traumatic PSAs in 7 patients treated using only PED placement...
June 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29695391/recurrence-of-a-totally-occluded-aneurysm-after-treatment-with-a-pipeline-embolization-device
#9
Felipe Padovani Trivelato, Alexandre Cordeiro Ulhôa, Marco Tulio Rezende, Luis Henrique Castro-Afonso, Daniel Giansante Abud
Treatment with a pipeline embolization device (PED) is widely accepted as an excellent option for patients harboring giant, wide neck, saccular intracranial aneurysms. It has been shown to be safe and very effective. We describe a previously unreported case of a large middle cerebral artery aneurysm, related to the carotid tip, that was treated with a PED and coils. The 6 month follow-up angiogram demonstrated complete occlusion of the aneurysm. However, the 9 month angiogram revealed recurrent filling of the aneurysm sac...
April 25, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29679782/outcomes-after-off-label-use-of-the-pipeline-embolization-device-for-intracranial-aneurysms-a-multicenter-cohort-study
#10
Samer G Zammar, Thomas J Buell, Ching-Jen Chen, R Webster Crowley, Dale Ding, Christoph J Griessenauer, Brian L Hoh, Kenneth C Liu, Christopher S Ogilvy, Daniel M Raper, Amit Singla, Ajith J Thomas, Kevin M Cockroft, Scott D Simon
OBJECTIVE: To examine outcomes of Pipeline embolization device (PED) use for treatment of intracranial aneurysms outside of U.S. Food and Drug Administration-approved indications. METHODS: Data from patients with aneurysms treated with off-label use of PED were pooled from 4 centers in a retrospective multicenter cohort study. Primary endpoints were decline in modified Rankin Scale score by at least 1 point and angiographic aneurysm occlusion at follow-up. RESULTS: The study cohort comprised 109 patients...
April 19, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29626682/patterns-predictors-and-outcomes-of-post-procedure-delayed-hemorrhage-following-flow-diversion-for-intracranial-aneurysm-treatment
#11
A C White, D A Kumpe, C D Roark, D E Case, J Seinfeld
PURPOSE: To evaluate patterns, predictors, and outcomes of post procedure delayed hemorrhage (PPDH) following flow diversion therapy for intracranial aneurysm. METHODS: 50 patients with 52 aneurysms were treated from 2012-2016 with the Pipeline Embolization Device (PED; Medtronic, Minneapolis, MN). PED placement was performed as a standalone therapy or with adjunctive coil embolization. Patients underwent dual antiplatelet therapy (DAT) for 6 months following treatment...
April 4, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29624153/occlusion-rates-of-intracranial-aneurysms-treated-with-the-pipeline-embolization-device-the-role-of-branches-arising-from-the-sac
#12
Felipe Padovani Trivelato, Marco Túlio Salles Rezende, Alexandre Cordeiro Ulhôa, Luis Henrique de Castro-Afonso, Guilherme Seizem Nakiri, Daniel Giansante Abud
OBJECTIVE The aim of this study was to compare the clinical and angiographic outcomes of intracranial aneurysms with and without branches arising from the sac after Pipeline embolization device (PED) treatment. METHODS This retrospective 2-center comparative study included 116 patients with 157 aneurysms that were treated with PEDs. Aneurysms were divided into 2 groups: one group had branches arising from the sac and the other group did not. Study end points included total aneurysm occlusion assessed by angiography at 6 and 12 months, death or stroke, technical complications, in-stent stenosis, patency of covered branches, and transient ischemia...
April 6, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29608702/flow-diversion-of-posterior-circulation-cerebral-aneurysms-a-single-institution-series-of-59-cases
#13
Matthew T Bender, Geoffrey P Colby, Bowen Jiang, Li-Mei Lin, Jessica K Campos, Risheng Xu, Erick M Westbroek, Chau D Vo, David A Zarrin, Justin M Caplan, Judy Huang, Rafael J Tamargo, Alexander L Coon
BACKGROUND: Posterior circulation cerebral aneurysms are at higher risk of rupture and are more symptomatic than those in the anterior circulation. Existing treatments carry significant morbidity. Early reports of flow diversion for posterior circulation aneurysms have suggested high complication and low occlusion rates. OBJECTIVE: To report safety and efficacy of flow diversion with the pipeline embolization device (ev3, Medtronic Inc, Dublin, Ireland) for aneurysms located throughout the posterior circulation...
March 28, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29600915/predictors-of-cerebral-aneurysm-persistence-and-occlusion-after-flow-diversion-a-single-institution-series-of-445-cases-with-angiographic-follow-up
#14
Matthew T Bender, Geoffrey P Colby, Li-Mei Lin, Bowen Jiang, Erick M Westbroek, Risheng Xu, Jessica K Campos, Judy Huang, Rafael J Tamargo, Alexander L Coon
OBJECTIVE Flow diversion requires neointimal stent overgrowth to deliver aneurysm occlusion. The existing literature on aneurysm occlusion is limited by heterogeneous follow-up, variable antiplatelet regimens, noninvasive imaging modalities, and nonstandard occlusion assessment. Using a large, single-center cohort with low attrition and standardized antiplatelet tapering, the authors evaluated outcomes after flow diversion of anterior circulation aneurysms to identify predictors of occlusion and aneurysm persistence...
March 30, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29600914/editorial-indication-and-technique-for-using-the-pipeline-embolization-device-to-treat-intracranial-aneurysms
#15
Jan-Karl Burkhardt, Omar Tanweer, Peter Kim Nelson, Howard A Riina
No abstract text is available yet for this article.
March 30, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29588236/predicting-successful-treatment-of-intracranial-aneurysms-with-the-pipeline-embolization-device-through-meta-regression
#16
Hind A Beydoun, Yasameen Azarbaijani, Hong Cheng, Colin Anderson-Smits, Danica Marinac-Dabic
OBJECTIVE: To conduct meta-regression for the identification of clinically meaningful characteristics that can predict successful treatment of intracranial aneurysms (IAs) with the Pipeline Embolization Device (PED). METHODS: Using the keyword "Pipeline Embolization Device" and pre-specified eligibility criteria, we searched PubMed and EMBASE and identified 105 original research articles (10,813 patients) published or in press (April 6, 2011-December 31, 2016) focused on safety and/or effectiveness of PED...
March 24, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29535896/treatment-of-intracranial-aneurysms-with-the-pipeline-embolization-device-only-a-single-center-experience
#17
Maus Volker, Mpotsaris Anastasios, Borggrefe Jan, Abdullayev Nuran, Liebig Thomas, Dorn Franziska, Stavrinou Pantelis, Chang De-Hua, Kabbasch Christoph
Purpose: The aim of this study was to evaluate the technical feasibility and rate of mid-term occlusion in aneurysms treated solely with the Pipeline Embolization Device (PED) in a German tertiary care university hospital. Materials and Methods: Forty-nine non-consecutive intracranial aneurysms underwent endovascular treatment using the PED exclusively between March 2011 and May 2017 at our institution. Primary endpoint was a favorable aneurysm occlusion defined as OKM C1-3 and D (O'Kelly Marotta Scale)...
March 2018: Neurointervention
https://www.readbyqxmd.com/read/29529233/flow-diversion-for-the-treatment-of-basilar-apex-aneurysms
#18
Adam A Dmytriw, Nimer Adeeb, Ashish Kumar, Christoph J Griessenauer, Kevin Phan, Christopher S Ogilvy, Paul M Foreman, Hussain Shallwani, Nicola Limbucci, Salvatore Mangiafico, Caterina Michelozzi, Timo Krings, Vitor Mendes Pereira, Charles C Matouk, Yuchen Zhang, Mark R Harrigan, Hakeem J Shakir, Adnan H Siddiqui, Elad I Levy, Leonardo Renieri, Christophe Cognard, Ajith J Thomas, Thomas R Marotta
BACKGROUND: Flow diversion for basilar apex aneurysms has rarely been reported. OBJECTIVE: To assess flow diversion for basilar apex aneurysms in a multicenter cohort. METHODS: Retrospective review of prospectively maintained databases at 8 academic institutions was performed from 2009 to 2016 to identify patients with basilar apex aneurysms treated with flow diversion. Clinical and radiographic data were analyzed. RESULTS: Sixteen consecutive patients (median age 54...
February 26, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29528441/endovascular-treatment-of-posterior-cerebral-artery-aneurysms-with-flow-diversion-case-series-and-systematic-review
#19
Adam N Wallace, Jonathan A Grossberg, Josser E Delgado Almandoz, Mudassar Kamran, Anil K Roy, Yasha Kayan, Matthew J Austin, Brian M Howard, Christopher J Moran, C Michael Cawley, DeWitte T Cross, Jacques E Dion, Akash P Kansagra, Joshua W Osbun
BACKGROUND: Flow diversion of posterior cerebral artery (PCA) aneurysms has not been widely reported, possibly owing to concerns regarding parent vessel size and branch vessel coverage. OBJECTIVE: To examine the safety and effectiveness of PCA aneurysm flow diverter treatment. METHODS: Retrospective review of PCA aneurysms treated with the Pipeline Embolization Device (PED; Medtronic Inc, Dublin, Ireland) at 3 neurovascular centers, including periprocedural complications and clinical and angiographic outcomes...
March 8, 2018: Neurosurgery
https://www.readbyqxmd.com/read/29524711/retrograde-snare-assisted-rescue-via-the-anterior-communicating-artery-for-lost-access-during-multiple-overlapping-pipeline-embolization-device-placement-a-technical-case-report
#20
Wonsoo Son, Dong-Hun Kang, Byung Moon Kim, Jaechan Park, Yong-Sun Kim
BACKGROUND: The pipeline embolization device (PED; ev3, Irvine, California, USA) has been used to divert flow away from an aneurysm sac. The risk of complications may increase for flow diversion with giant aneurysms, since these cases may require multiple overlapping PEDs, which makes the technique highly complex. CASE DESCRIPTION: We report a rescue technical strategy for lost access during multiple overlapping PED placement for a giant, fusiform cavernous aneurysm...
March 7, 2018: World Neurosurgery
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