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https://www.readbyqxmd.com/read/28813095/evaluation-of-cell-proliferation-and-endometrial-thickness-of-bitches-in-different-periods-of-diestrus
#1
Vanessa S A Gossler, Francislaine A G Santos, Aline R DE Azevedo, Priscila C Gonçalves, Hugo A Rigolo, Cleonice Trevisan, Ana Paula B Masseno, Ana Paula M M Cardoso, Paula C Papa, Caliê Castilho, Ines C Giometti
This study aimed to determine the histological features of the endometrium of bitches, as well as the cell proliferation at specific moments of diestrus, 10, 20, 30, 40, 50 and 60 days post ovulation, correlating the endometrial thickness with the uterine cell proliferation and the metabolic state (weight, blood glucose and plasma cholesterol) of the animals. Therefore, the right and left uterine horns of 26 clinically healthy bitches submitted to ovariohysterectomy were histologically analyzed 10, 20, 30, 40, 50 and 60 days post ovulation...
August 14, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28813090/brazilian-consensus-on-duchenne-muscular-dystrophy-part-1-diagnosis-steroid-therapy-and-perspectives
#2
Alexandra P Q C Araujo, Alzira A S de Carvalho, Eduardo B U Cavalcanti, Jonas Alex M Saute, Elmano Carvalho, Marcondes C França, Alberto R M Martinez, Monica de M M Navarro, Anamarli Nucci, Maria Bernadete D de Resende, Marcus Vinicius M Gonçalves, Juliana Gurgel-Giannetti, Rosana H Scola, Cláudia F da R Sobreira, Umbertina C Reed, Edmar Zanoteli
Significant advances in the understanding and management of Duchenne muscular dystrophy (DMD) took place since international guidelines were published in 2010. Our objective was to provide an evidence-based national consensus statement for multidisciplinary care of DMD in Brazil. A combination of the Delphi technique with a systematic review of studies from 2010 to 2016 was employed to classify evidence levels and grade of recommendations. Our recommendations were divided in two parts. We present Part 1 here, where we describe the guideline methodology and overall disease concepts, and also provide recommendations on diagnosis, steroid therapy and new drug treatment perspectives for DMD...
August 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28813055/multivesicular-droplets-a-cell-model-system-to-study-compartmentalised-biochemical-reactions
#3
N Nuti, P E Verboket, P S Dittrich
Multivesicular vesicles (MVVs) are artificial liposomal structures widely used as a platform to study the compartmentalisation of cells and as a scaffold for artificial cell/protocell models. Current preparation techniques for MVVs, however, offer poor control on the size, lamellarity, and loading of inner lipid vesicles. Here, we introduce a microfluidic device for the production of multivesicular droplets (MVDs): a novel model system combining the ease of use and control of droplet microfluidics with the biological relevance of MVVs...
August 16, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28813033/a-vision-based-wayfinding-system-for-visually-impaired-people-using-situation-awareness-and-activity-based-instructions
#4
Eunjeong Ko, Eun Yi Kim
A significant challenge faced by visually impaired people is 'wayfinding', which is the ability to find one's way to a destination in an unfamiliar environment. This study develops a novel wayfinding system for smartphones that can automatically recognize the situation and scene objects in real time. Through analyzing streaming images, the proposed system first classifies the current situation of a user in terms of their location. Next, based on the current situation, only the necessary context objects are found and interpreted using computer vision techniques...
August 16, 2017: Sensors
https://www.readbyqxmd.com/read/28813028/detection-methodologies-for-pathogen-and-toxins-a-review
#5
REVIEW
Md Eshrat E Alahi, Subhas Chandra Mukhopadhyay
Pathogen and toxin-contaminated foods and beverages are a major source of illnesses, even death, and have a significant economic impact worldwide. Human health is always under a potential threat, including from biological warfare, due to these dangerous pathogens. The agricultural and food production chain consists of many steps such as harvesting, handling, processing, packaging, storage, distribution, preparation, and consumption. Each step is susceptible to threats of environmental contamination or failure to safeguard the processes...
August 16, 2017: Sensors
https://www.readbyqxmd.com/read/28813006/samarium-monosulfide-sms-reviewing-properties-and-applications
#6
REVIEW
Andreas Sousanis, Philippe F Smet, Dirk Poelman
In this review, we give an overview of the properties and applications of samarium monosulfide, SmS, which has gained considerable interest as a switchable material. It shows a pressure-induced phase transition from the semiconducting to the metallic state by polishing, and it switches back to the semiconducting state by heating. The material also shows a magnetic transition, from the paramagnetic state to an antiferromagnetically ordered state. The switching behavior between the semiconducting and metallic states could be exploited in several applications, such as high density optical storage and memory materials, thermovoltaic devices, infrared sensors and more...
August 16, 2017: Materials
https://www.readbyqxmd.com/read/28813004/lactose-binding-induces-opposing-dynamics-changes-in-human-galectins-revealed-by-nmr-based-hydrogen-deuterium-exchange
#7
Chih-Ta Henry Chien, Meng-Ru Ho, Chung-Hung Lin, Shang-Te Danny Hsu
Galectins are β-galactoside-binding proteins implicated in a myriad of biological functions. Despite their highly conserved carbohydrate binding motifs with essentially identical structures, their affinities for lactose, a common galectin inhibitor, vary significantly. Here, we aimed to examine the molecular basis of differential lactose affinities amongst galectins using solution-based techniques. Consistent dissociation constants of lactose binding were derived from nuclear magnetic resonance (NMR) spectroscopy, intrinsic tryptophan fluorescence, isothermal titration calorimetry and bio-layer interferometry for human galectin-1 (hGal1), galectin-7 (hGal7), and the N-terminal and C-terminal domains of galectin-8 (hGal8(NTD) and hGal8(CTD), respectively)...
August 16, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28812999/synthesis-and-evaluation-of-a-sodium-alginate-4-aminosalicylic-acid-based-microporous-hydrogel-for-potential-viscosupplementation-for-joint-injuries-and-arthritis-induced-conditions
#8
Dharmesh R Chejara, Mostafa Mabrouk, Pradeep Kumar, Yahya E Choonara, Pierre P D Kondiah, Ravindra V Badhe, Lisa C du Toit, Divya Bijukumar, Viness Pillay
A microporous hydrogel was developed using sodium alginate (alg) and 4-aminosalicylic acid (4-ASA). The synthesized hydrogel was characterized using various analytical techniques such as Fourier transform infrared spectroscopy (FTIR), Carbon-13 nuclear magnetic resonance ((13)C-NMR), X-ray powder diffraction (XRD), scanning electron microscopy (SEM), and differential scanning calorimetry (DSC). Additonal carboxyl and hydroxyl functional groups of 4-ASA provided significant lubrication and stress-triggered sol-gel transition to the conjugated hydrogel...
August 16, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28812995/optimizing-waveform-maximum-determination-for-specular-point-tracking-in-airborne-gnss-r
#9
Erwan Motte, Mehrez Zribi
Airborne GNSS-R campaigns are crucial to the understanding of signal interactions with the Earth's surface. As a consequence of the specific geometric configurations arising during measurements from aircraft, the reflected signals can be difficult to interpret under certain conditions like over strongly attenuating media such as forests, or when the reflected signal is contaminated by the direct signal. For these reasons, there are many cases where the reflectivity is overestimated, or a portion of the dataset has to be flagged as unusable...
August 16, 2017: Sensors
https://www.readbyqxmd.com/read/28812944/binding-forces-between-a-novel-schiff-base-palladium-ii-complex-and-two-carrier-proteins-human-serum-albumi-and%C3%AE-lactoglobulin
#10
Somaye Shahraki, Ali Heydari
Ligand binding studies on carrier proteins are crucial in determining the pharmacological properties of drug candidates. Here, a new palladium(II) complex was synthesized and characterized. The in vitro binding studies of this complexwith two carrier proteins, human serum albumin (HSA) and β-lactoglobulin (βLG) was investigated by employing biophysical techniques as well as computational modeling. The experimental results showed thatthe Pd(II) complex interacted with two carrier proteins with moderate binding affinity (Kb ~̴ 0...
August 16, 2017: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/28812913/transcanalicular-laser-assisted-dacryocystorhinostomy-with-diode-laser
#11
Deepesh Mourya, Roshija Khanal Rijal
This article compares the efficacy of transcanalicular laser assisted dacryocystorhinostomy (TL DCR) with conventional external dacryocystorhinostomy (Ex DCR). All patients were randomly divided into two groups - Group A included patients who underwent TL DCR and Group B included patients who underwent Ex DCR. 168 operations were done in a total of 163 patients; 79 patients in group A and 84 patients in group B. The overall success rate was 90.12% in group A and 95.40% in group B. The mean total surgical time was 17...
August 16, 2017: Orbit
https://www.readbyqxmd.com/read/28812877/scru2b3-and-sc2rub6-borides-featuring-a-2d-infinite-boron-clustering
#12
Leonid P Salamakha, Oksana Sologub, Berthold Stöger, Peter Franz Rogl, Monika Waas, Volodymyr B Kapustianyk, Ernst Bauer
Two borides, ScRu2B3 and Sc2RuB6, were obtained by argon-arc melting of the elements followed by annealing at 800 °C. ScRu2B3 exhibits a new structure type with the space group Cmcm (a = 3.0195(2) Å, b = 15.4056(8) Å, c = 5.4492(3) Å; single crystal X-ray data; RF(2) = 0.0105). Sc2RuB6 adopts the Y2ReB6-type structure (space group Pbam; a = 8.8545(2) Å, b = 11.1620(3) Å, c = 3.4760(1) Å; single crystal X-ray data; RF(2) = 0.0185). ScRu2B3 displays an unusual intergrowth of CeCo3B2- and AlB2-related slabs; a striking feature is a boat configuration of puckered boron hexagons within infinite graphite like boron layers (6(3) nets)...
August 16, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28812827/-seeing-the-difference-the-importance-of-visibility-and-action-as-a-mark-of-authenticity-in-co-production-comment-on-collaboration-and-co-production-of-knowledge-in-healthcare-opportunities-and-challenges
#13
Jo Cooke, Joe Langley, Dan Wolstenholme, Susan Hampshaw
The Rycroft-Malone paper states that co-production relies on 'authentic' collaboration as a context for action. Our commentary supports and extends this assertion. We suggest that 'authentic' co-production involves processes where participants can 'see' the difference that they have made within the project and beyond. We provide examples including: the use of design in health projects which seek to address power issues and make contributions visible through iteration and prototyping; and the development of 'actionable outputs' from research that are the physical embodiment of co-production...
October 17, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812805/changes-in-socio-economic-inequality-in-neonatal-mortality-in-iran-between-1995-2000-and-2005-2010-an-oaxaca-decomposition-analysis
#14
Mostafa Amini Rarani, Arash Rashidian, Ardeshir Khosravi, Mohammad Arab, Ezatollah Abbasian, Esmaeil Khedmati Morasae
BACKGROUND: Exploring changes in health inequality and its determinants over time is of policy interest. Accordingly, this study aimed to decompose inequality in neonatal mortality into its contributing factors and then explore changes from 1995-2000 to 2005-2010 in Iran. METHODS: Required data were drawn from two Iran's demographic and health survey (DHS) conducted in 2000 and 2010. Normalized concentration index (CI) was used to measure the magnitude of inequality in neonatal mortality...
September 24, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812774/self-adaptive-hydrogels-to-mineralization
#15
Tooba Shoaib, Ariel Carmichael, R E Corman, Yun Shen, Thanh H Nguyen, Randy H Ewoldt, Rosa M Espinosa-Marzal
Mineralized biological tissues, whose behavior can range from rigid to compliant, are an essential component of vertebrates and invertebrates. Little is known about how the behavior of mineralized yet compliant tissues can be tuned by the degree of mineralization. In this work, a synthesis route to tune the structure and mechanical response of agarose gels via ionic crosslinking and mineralization has been developed. A combination of experimental techniques demonstrates that crosslinking via cooperative hydrogen bonding in agarose gels is disturbed by calcium ions, but they promote ionic crosslinking that modifies the agarose network...
August 16, 2017: Soft Matter
https://www.readbyqxmd.com/read/28812699/primate-brain-size-is-predicted-by-diet-but-not-sociality
#16
Alex R DeCasien, Scott A Williams, James P Higham
The social brain hypothesis posits that social complexity is the primary driver of primate cognitive complexity, and that social pressures ultimately led to the evolution of the large human brain. Although this idea has been supported by studies indicating positive relationships between relative brain and/or neocortex size and group size, reported effects of different social and mating systems are highly conflicting. Here, we use a much larger sample of primates, more recent phylogenies, and updated statistical techniques, to show that brain size is predicted by diet, rather than multiple measures of sociality, after controlling for body size and phylogeny...
March 27, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28812541/systematic-review-of-interventions-for-treating-or-preventing-antipsychotic-induced-tardive-dyskinesia
#17
Hanna Bergman, Dawn-Marie Walker, Adriani Nikolakopoulou, Karla Soares-Weiser, Clive E Adams
BACKGROUND: Antipsychotic medication can cause tardive dyskinesia (TD) - late-onset, involuntary, repetitive movements, often involving the face and tongue. TD occurs in > 20% of adults taking antipsychotic medication (first-generation antipsychotics for > 3 months), with this proportion increasing by 5% per year among those who continue to use these drugs. The incidence of TD among those taking newer antipsychotics is not different from the rate in people who have used older-generation drugs in moderate doses...
August 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28812536/edgar-a-database-of-disease-gene-associations-with-annotated-relationships-among-genes
#18
Giulia Babbi, Pier Luigi Martelli, Giuseppe Profiti, Samuele Bovo, Castrense Savojardo, Rita Casadio
BACKGROUND: Genetic investigations, boosted by modern sequencing techniques, allow dissecting the genetic component of different phenotypic traits. These efforts result in the compilation of lists of genes related to diseases and show that an increasing number of diseases is associated with multiple genes. Investigating functional relations among genes associated with the same disease contributes to highlighting molecular mechanisms of the pathogenesis. RESULTS: We present eDGAR, a database collecting and organizing the data on gene/disease associations as derived from OMIM, Humsavar and ClinVar...
August 11, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28812529/approaches-to-evaluate-lung-inflammation-in-translational-research
#19
David K Meyerholz, Jessica C Sieren, Amanda P Beck, Heather A Flaherty
Inflammation is a common feature in several types of lung disease and is a frequent end point to validate lung disease models, evaluate genetic or environmental impact on disease severity, or test the efficacy of new therapies. Questions relevant to a study should be defined during experimental design and techniques selected to specifically address these scientific queries. In this review, the authors focus primarily on the breadth of techniques to evaluate lung inflammation that have both clinical and preclinical applications...
January 1, 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28812504/practising-mindfulness
#20
Irene Gilsenan
What was the nature of the CPD activity, practice-related feedback and/or event and/or experience in your practice? The article examined the use of mindfulness techniques and how by learning to care for themselves, nurses can enhance the care they provide for patients. The concept of mindfulness has had widespread publicity, from meditation courses to adult colouring books, but I wanted to learn how mindfulness can be applied to nursing.
August 16, 2017: Nursing Standard
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