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https://www.readbyqxmd.com/read/28808577/transition-from-intravenous-to-enteral-ketamine-for-treatment-of-nonconvulsive-status-epilepticus
#1
Michael A Pizzi, Prasuna Kamireddi, William O Tatum, Jerry J Shih, Daniel A Jackson, William D Freeman
BACKGROUND: Nonconvulsive status epilepticus (NCSE) is a diagnosis that is often challenging and one that may progress to refractory NCSE. Ketamine is a noncompetitive N-methyl-d-aspartate antagonist that increasingly has been used to treat refractory status epilepticus. Current Neurocritical Care Society guidelines recommend intravenous (IV) ketamine infusion as an alternative treatment for refractory status epilepticus in adults. On the other hand, enteral ketamine use in NCSE has been reported in only 6 cases (1 adult and 5 pediatric) in the literature to date...
2017: Journal of Intensive Care
https://www.readbyqxmd.com/read/28807456/post-hospitalization-experiences-of-older-adults-diagnosed-with-diabetes-it-was-daunting
#2
Jacqueline B La Manna, Angeline Bushy, Denise Gammonley
Multimorbidity combined with geriatric syndromes in older adults with diabetes exacerbate their risks for poor post-discharge outcomes. The purpose of this study was to examine self-described hospital-to-home transition challenges encountered by older adults with a diagnosis of diabetes within the first 30 days following discharge. The qualitative responses for this paper emerged from a larger mixed methods study (n = 96) in which participants provided free responses specifying transition challenges during follow-up telephone interviews on the 7th day (n = 67) and 30th day (n = 55) post-discharge...
August 11, 2017: Geriatric Nursing
https://www.readbyqxmd.com/read/28800751/prevalence-awareness-treatment-and-control-of-dyslipidemia-in-older-persons-in-urban-and-rural-population-in-the-astana-region-kazakhstan
#3
Adil Supiyev, Talgat Nurgozhin, Zhaxybay Zhumadilov, Anne Peasey, Jaroslav A Hubacek, Martin Bobak
BACKGROUND: Despite high cardiovascular mortality in Central Asian republics of the former Soviet Union, there is limited information about major risk factors, including blood lipids. We investigated the prevalence of impaired concentrations of blood lipids, the awareness, treatment and control of hypercholesterolemia, and factors associated with these indicators in urban and rural populations in Kazakhstan. METHODS: We conducted a cross-sectional study of random urban and rural population samples (the state capital Astana and Akmol village)...
August 11, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28795220/achieving-and-maintaining-lung-volume-in-the-preterm-infant-from-the-first-breath-to-the-nicu
#4
REVIEW
Gianluca Lista, Andrés Maturana, Fernando R Moya
Please check if statements under Abstract section are presented correctly.The main goal for the neonatologist is to facilitate the adaptation to extra-uterine life during initial transition, while minimizing lung injury opening and protecting the premature lung from the first breath onwards. An appropriate management from birth should lead to the achievement of an early functional residual capacity (FRC), and the following steps should aim at maintaining an adequate lung volume. To date, different strategies are available to optimize fetal-neonatal transition and promote lung recruitment...
August 10, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28793893/the-role-of-hospitals-in-bridging-the-care-continuum-a-systematic-review-of-coordination-of-care-and-follow-up-for-adults-with-chronic-conditions
#5
Melissa De Regge, Kaat De Pourcq, Bert Meijboom, Jeroen Trybou, Eric Mortier, Kristof Eeckloo
BACKGROUND: Multiple studies have investigated the outcome of integrated care programs for chronically ill patients. However, few studies have addressed the specific role hospitals can play in the downstream collaboration for chronic disease management. Our objective here is to provide a comprehensive overview of the role of the hospitals by synthesizing the advantages and disadvantages of hospital interference in the chronic discourse for chronically ill patients found in published empirical studies...
August 9, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28792079/mentoring-relationship-quality-and-maltreated-children-s-coping
#6
Ashley A Chesmore, Lindsey M Weiler, Heather N Taussig
Coping strategies are believed to protect against the harmful effects of maltreatment on children's psychosocial outcomes. Caregivers are thought to be critical in helping children develop adaptive coping strategies, yet many maltreated children have poor and/or insecure relationships with their parents. A quality relationship with a caring, non-parental adult (e.g., a mentor), however, may be one strategy to promote healthy coping among maltreated children. Children (N = 154) in this study participated in a mentoring and skill-based program for maltreated preadolescents placed in foster care...
August 9, 2017: American Journal of Community Psychology
https://www.readbyqxmd.com/read/28768492/the-effect-of-youth-assertive-community-treatment-a-systematic-prisma-review
#7
Richard Vijverberg, Robert Ferdinand, Aartjan Beekman, Berno van Meijel
BACKGROUND: During the past decades deinstitutionalisation policies have led to a transition from inpatient towards community mental health care. Many European countries implement Assertive Community Treatment (ACT) as an alternative for inpatient care for "difficult to reach" children and adolescents with severe mental illness. ACT is a well-organized low-threshold treatment modality; patients are actively approached in their own environment, and efforts are undertaken to strengthen the patient's motivation for treatment...
August 2, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28764794/exploration-of-knowledge-and-understanding-in-patients-with-primary-adrenal-insufficiency-a-mixed-methods-study
#8
L M Shepherd, A A Tahrani, C Inman, W Arlt, D M Carrick-Sen
BACKGROUND: Primary adrenal insufficiency (PAI) is a rare and severe condition requiring lifelong steroid replacement. During acute illness or stressful events, it is important to appropriately adjust glucocorticoid dose; failure to do so may lead to an adrenal crisis. The aim of the study was to explore patients PAI knowledge and understanding of the condition, steroid replacement adjustment during acute illness or stress and provided education. METHODS: Ten adult patients with PAI were purposefully recruited from two hospitals in a tertiary NHS Trust in England, UK...
August 1, 2017: BMC Endocrine Disorders
https://www.readbyqxmd.com/read/28761657/improving-the-transition-from-pediatric-to-adult-diabetes-care-the-pediatric-care-provider-s-perspective-in-quebec-canada
#9
Meranda Nakhla, Lorraine E Bell, Sarah Wafa, Kaberi Dasgupta
OBJECTIVES: The transition from pediatric to adult care is a high-risk period for the emerging adult with diabetes. We aimed to determine adequacy of pediatric transition care structures and explore the pediatric diabetes care provider's perceptions of transition care. RESEARCH DESIGN AND METHODS: In-depth interviews with pediatric diabetes care providers from 12 diabetes centers in Quebec were conducted. We queried alignment with Got Transition's six core elements of healthcare transition, experiences, and barriers to transition care...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28760316/developing-a-transition-care-coordination-program-for-youth-with-spina-bifida
#10
Amanda Seeley, Linda Lindeke
INTRODUCTION: This quality improvement pilot study focused on developing and facilitating readiness for transition in youth with spina bifida. The results contribute to a broader institution-wide initiative at a subspecialty pediatric organization. METHODS: The clinical roles of six nurse care coordinators were restructured to add responsibility for transition care coordination. Together, parents, youth, and nurse transition care coordinators created and implemented individualized family-centered care plans focused on improving self-management and readiness for transition to adulthood...
July 28, 2017: Journal of Pediatric Health Care
https://www.readbyqxmd.com/read/28755059/nusinersen-the-first-option-beyond-supportive-care-for-spinal-muscular-atrophy
#11
REVIEW
Vikas Maharshi, Shazia Hasan
Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disorder characterized by degeneration of spinal motor neurons and poses significant adverse outcome in affected population. Survival motor neuron 1 (SMN1) protein encoded by SMN1 gene located on 5q(13) is critical for survival and functioning of motor neurons. Almost identical gene SMN2, present on the same chromosome, produces a small truncated protein (SMN2) because of skipping of exon 7 from translation due to translation silent C6U substitution in exon 7 of SMN2 pre-mRNA transcript...
July 28, 2017: Clinical Drug Investigation
https://www.readbyqxmd.com/read/28754584/adolescent-to-adult-hiv-health-care-transition-from-the-perspective-of-adult-providers-in-the-united-states
#12
Amanda E Tanner, Morgan M Philbin, Alice Ma, Brittany D Chambers, Sharon Nichols, Sonia Lee, J Dennis Fortenberry
PURPOSE: The HIV Care Continuum highlights the need for HIV-infected youth to be tested, linked, and maintained in lifelong care. Care engagement is important for HIV-infected youth in order for them to stay healthy, maintain a low viral load, and reduce further transmission. One point of potential interruption in the care continuum is during health care transition from adolescent- to adult-centered HIV care. HIV-related health care transition research focuses mainly on youth and on adolescent clinic providers; missing is adult clinic providers' perspectives...
July 25, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28753177/assessing-the-transition-intervention-needs-of-young-adults-with-inflammatory-bowel-diseases
#13
Natalie R Klostermann, Laura McAlpine, Eytan Wine, Karen J Goodman, Karen I Kroeker
OBJECTIVES: The transition of inflammatory bowel disease (IBD) patients from pediatric to adult care can be challenging. Developing an effective transition intervention requires assessing the current transition experience for potential improvements, determining preferred content and format, and assessing patients' transition skills. METHODS: This mixed-methods study of 20 transitioned IBD patients (ages 17-20 years) utilized semi-structured interviews and validated assessments of self-management/self-advocacy and IBD knowledge...
July 27, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28753042/increased-detection-of-co-morbidities-with-evaluation-at-a-dedicated-adult-turner-syndrome-clinic
#14
A J Vincent, H H Nguyen, S Ranasinha, B Vollenhoven
OBJECTIVES: Turner syndrome (TS), resulting from complete/partial X chromosomal monosomy, is associated with multiple co-morbidities and increased mortality. Although multidisciplinary management is recommended, TS women's health care is sub-optimal. This study evaluates a multidisciplinary adult TS service. METHODS: Retrospective cohort study of 82 patients attending the quarterly TS clinic from December 2003 to December 2014. Evaluation included (1) demographics, (2) TS standardized co-morbidity screening, and (3) estrogen therapy use...
July 28, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28751537/management-of-kawasaki-disease-in-adults
#15
REVIEW
Kara J Denby, Daniel E Clark, Larry W Markham
Kawasaki disease is the most common childhood vasculitis in the USA and the most common cause of acquired cardiac disease in children in developed countries. Since the vast majority of Kawasaki disease initially presents at <5 years of age, many adult cardiologists are unfamiliar with the pathophysiology of this disease. This vasculitis has a predilection for coronary arteries with a high complication rate across the lifespan for those with medium to large coronary artery aneurysms. An inflammatory cascade produces endothelial dysfunction and damage to the vascular wall, leading to aneurysmal dilatation...
July 27, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28735347/the-impact-of-eldercare-on-adult-children-s-health-and-employment-in-transitional-china
#16
Xiaomei Pei, Hao Luo, Zhiyong Lin, Norah Keating, Janet Fast
This paper explores the content and extent of the burden of caregiving for Chinese families in transition. It sets out to understand how Chinese families manage to balance family caregiving responsibilities with employment, the impact of the existing social institutions on family caregiving practices, and the risks that caregivers have to face. Data were collected from a sample of 214 workers from 14 manufacturing companies in an industrialized city in central China in 2013. Analysis revealed that common types of eldercare were assisting with activities of daily living and medical related care; middle aged employed respondents were most likely to be the caregivers to older family members; financial and time demands of care were challenging for caregivers, but women with more education and a secure job responded to the pressure of care giving better than those with less education and insecure jobs...
July 22, 2017: Journal of Cross-cultural Gerontology
https://www.readbyqxmd.com/read/28734126/german-estsmoke-estimating-adult-smoking-related-costs-and-consequences-of-smoking-cessation-for-germany
#17
Diana Sonntag, Simon Gilbody, Winkler Volker, Shehzad Ali
AIMS: We compared predicted lifetime health care costs for current, never and ex-smokers in Germany under the current set of tobacco control polices. We compared these economic consequences of the current situation with an alternative in which Germany were to implement more comprehensive tobacco control policies consistent with the WHO Framework Convention for Tobacco Control (FCTC) guidelines. DESIGN: German EstSmoke, an adapted version of the UK EstSmoke simulation model, applies the Markov modelling approach...
July 22, 2017: Addiction
https://www.readbyqxmd.com/read/28732796/transition-from-paediatric-care-to-adult-care-for-patients-with-mucopolysaccharidosis
#18
M L Couce, M Del Toro, M C García-Jiménez, L Gutierrez-Solana, Á Hermida-Ameijeiras, M López-Rodríguez, J Pérez-López, M Á Torralba
Mucopolysaccharidosis are multisystem diseases that require large multidisciplinary teams for their care. Specific recommendations are therefore needed for the transition from childhood to adulthood in this patient group. To overcome the barriers that might arise during the transition, the authors consider it essential to implement a flexible plan with a coordinator for the entire process, systematising the information through a standardised paediatric discharge report and educating the patient and their family about the disease, showing the characteristics of the healthcare system in this new stage...
July 18, 2017: Revista Clínica Española
https://www.readbyqxmd.com/read/28725847/the-process-and-impact-of-stakeholder-engagement-in-developing-a-pediatric-intensive-care-unit-communication-and-decision-making-intervention
#19
Kelly N Michelson, Joel Frader, Lauren Sorce, Marla L Clayman, Stephen D Persell, Patricia Fragen, Jody D Ciolino, Laura C Campbell, Melanie Arenson, Danica Y Aniciete, Melanie L Brown, Farah N Ali, Douglas White
Stakeholder-developed interventions are needed to support pediatric intensive care unit (PICU) communication and decision-making. Few publications delineate methods and outcomes of stakeholder engagement in research. We describe the process and impact of stakeholder engagement on developing a PICU communication and decision-making support intervention. We also describe the resultant intervention. Stakeholders included parents of PICU patients, healthcare team members (HTMs), and research experts. Through a year-long iterative process, we involved 96 stakeholders in 25 meetings and 26 focus groups or interviews...
December 2016: Journal of patient experience
https://www.readbyqxmd.com/read/28725255/transition-into-adult-care-factors-associated-with-level-of-preparedness-among-adolescents-living-with-hiv-in-cambodia
#20
Siyan Yi, Chanrith Ngin, Khuondyla Pal, Vohith Khol, Sovannary Tuot, Sokunmealiny Sau, Pheak Chhoun, Gitau Mburu, Sok Chamreun Choub, Kolab Chhim, Penhsun Ly
BACKGROUND: Preparing adolescents for transition into adult care and supporting their acquisition of self-health care management skills is a critical determinant of their post-transition HIV care outcomes. However, there is a scarcity of research on effective transition strategies. This study explores factors associated with adolescent preparedness for transition into adult care in Cambodia. METHODS: In August 2016, a cross-sectional study was conducted among 223 adolescents living with HIV aged 15-17, randomly selected from 11 antiretroviral therapy clinics, utilizing a structured questionnaire...
2017: AIDS Research and Therapy
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