keyword
https://read.qxmd.com/read/38462432/safety-monitoring-of-bivalent-mrna-covid-19-vaccine-among-pregnant-persons-in-the-vaccine-adverse-event-reporting-system-united-states-september-1-2022-march-31-2023
#21
JOURNAL ARTICLE
Pedro L Moro, Grace Carlock, Nimita Fifadara, Tei Habenicht, Bicheng Zhang, Penelope Strid, Paige Marquez
BACKGROUND: Pregnant persons are at increased risk of severe COVID-19 illness. Bivalent mRNA COVID-19 vaccination is recommended for everyone, including pregnant persons. However, data are limited on the safety of bivalent mRNA COVID-19 vaccination during pregnancy. OBJECTIVE: To evaluate and summarize reports to the Vaccine Adverse Event Reporting System (VAERS), a national spontaneous reporting system, among pregnant persons who received bivalent mRNA COVID-19 vaccine...
March 9, 2024: Vaccine
https://read.qxmd.com/read/38460343/analysis-of-perinatal-risk-factors-for-massive-pulmonary-hemorrhage-in-very-low-birth-weight-infant-a-nationwide-large-cohort-database
#22
JOURNAL ARTICLE
Jong Ki Jung, Eun Yeob Kim, Ju Sun Heo, Kyu Hee Park, Byung Min Choi
OBJECTIVE: To determine perinatal risk factors for Massive pulmonary hemorrhage (MPH) and MPH-caused mortality to guide clinicians in implementing preventive measures at the beginning of life for improving the survival of very low birth weight infant (VLBWIs). STUDY DESIGN: A total of 13,826 VLBWIs born between 2013 and 2020 in the Korean Neonatal Network database were included. RESULTS: MPH occurred in 870 (6.3 %) VLBWIs. Among infants with MPH, 162 (18...
March 5, 2024: Early Human Development
https://read.qxmd.com/read/38454005/association-between-patent-ductus-arteriosus-flow-and-home-oxygen-therapy-in-extremely-preterm-infants
#23
JOURNAL ARTICLE
Jana Termerova, Ales A Kubena, Karel Liska, Viktor Tomek, Richard Plavka
BACKGROUND: Central blood flow measurements include the estimation of right and left ventricular output (RVO, LVO), superior vena cava (SVC) flow, and calculated patent ductus arteriosus (PDA) flow. We aimed to provide an overview of the maturation patterns of these values and the relationship between PDA flow and the need for home oxygen therapy. METHODS: This prospective single-center study was conducted in infants born at <26 weeks of gestation. We performed echocardiographic measurements five times during their life (from the 4th post-natal day to the 36th postmenstrual week)...
March 7, 2024: Pediatric Research
https://read.qxmd.com/read/38452632/active-versus-restrictive-ligation-strategy-for-patent-ductus-arteriosus-a-retrospective-two-center-study-of-extremely-preterm-infants-born-between-22%C3%A2-%C3%A2-0-and-25%C3%A2-%C3%A2-6%C3%A2-weeks-of-gestational-age
#24
JOURNAL ARTICLE
Fanny Söderström, Richard Sindelar, Karl Wilhelm Olsson, Sawin Yousef, Daniela Todorova, Joanna Pestalozzi, Mats Mellander, Renske Raaijmakers
BACKGROUND: Patent ductus arteriosus (PDA) in premature infants is associated with adverse clinical outcomes. Mode and timing of treatment are still controversial. Data are limited in the most extremely premature infants <26 weeks of gestational age (GA), where clinical problems are most significant and patients are most vulnerable. AIMS: To investigate whether different approaches to surgical closure of PDA in two large Swedish centers has an impact on clinical outcomes including mortality in extremely preterm infants born <26 weeks GA...
February 29, 2024: Early Human Development
https://read.qxmd.com/read/38447536/cyanotic-nephropathy-in-an-adult-patient-with-eisenmenger-syndrome-a-case-report-and-literature-review
#25
Fanyou Zhu, Rui Wen, Xiangling Tan, Hongjun Nie, Jiali Li, Qi Wang, Jiao Qin
INTRODUCTION: Cyanotic nephropathy, a rare disease characterized by proteinuria, decreased estimated glomerular filtration rate (eGFR), thrombocytopenia, polycythemia, and hyperuricemia, may occasionally be secondary to cyanotic congenital heart disease. There are currently no detailed diagnostic criteria or treatments for cyanotic nephropathy owing to its extremely low incidence. Eisenmenger syndrome (ES) was initially defined by Paul Wood in pathophysiologic terms as "pulmonary hypertension (PH) at the systemic level, caused by a high pulmonary vascular resistance (PVR), with a reversed or bidirectional shunt at aorto-pulmonary, ventricular, or atrial level...
March 6, 2024: Kidney & Blood Pressure Research
https://read.qxmd.com/read/38445694/comparative-analysis-of-machine-learning-algorithms-evaluating-the-single-nucleotide-polymorphisms-of-metabolizing-enzymes-with-clinical-outcomes-following-intravenous-paracetamol-in-preterm-neonates-with-patent-ductus-arteriosus
#26
JOURNAL ARTICLE
Kannan Sridharan, George Priya Doss C, Hephzibah Cathryn R, Thirumal Kumar D, Muna Al Jufairi
AIMS: Pharmacogenomics has been identified to play a crucial role in determining drug response. The present study aimed to identify significant genetic predictor variables influencing the therapeutic effect of paracetamol for new indications in preterm neonates. BACKGROUND: Paracetamol has recently been preferred as a first-line drug for managing Patent Ductus Arteriosus (PDA) in preterm neonates. Single Nucleotide Polymorphisms (SNPs) in CYP1A2, CYP2A6, CYP2D6, CYP2E1, and CYP3A4 have been observed to influence the therapeutic concentrations of paracetamol...
March 5, 2024: Current Drug Metabolism
https://read.qxmd.com/read/38440550/syndromic-piere-robbin-sequence-a-rare-presentation-in-association-with-multiple-heart-defects-and-type-iii-stickler-syndrome
#27
JOURNAL ARTICLE
Soubia Akhtar, Muhammad Wasif, Yumna Afzal, Iqra Shahab, Rahim Dhanani, Abdul Rauf Shaikh
Pierre Robin Sequence (PRS), a rare congenital disorder, is a triad of micrognathia, glossoptosis, and tongue based airway obstruction (TBSO). It may occur as isolated anomaly (iPRS) or as a part of a syndrome (sPRS), like that seen in association with Stickler Syndrome. Approximately 20% of children with PRS have congenital heart diseases. To the best of our knowledge this case of a one-day old infant is the first one to be reported as having two heart defects; patent ductus arteriosus and patent foramen ovale in Pierre Robbin Sequence child...
February 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/38432888/clinical-characteristics-of-bronchopulmonary-dysplasia-in-very-preterm-infants
#28
JOURNAL ARTICLE
Yonghui Yang, Xiaori He, Xuefei Zhang, Pingyang Chen
OBJECTIVES: With the development of perinatal and neonatal intensive care medicine, the survival rate of very premature infants increases year by year. However, the incidence of bronchopulmonary dysplasia (BPD) increases year by year, which seriously affects the survival prognosis of very premature infants. How to prevent and treat BPD effectively has become the focus of neonatologists. This study aims to provide ideas for the prevention and treatment of BPD in very preterm infants via analyzing the clinical characteristics of BPD...
October 28, 2023: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://read.qxmd.com/read/38431545/is-takotsubo-syndrome-induced-by-patent-ductus-arteriosus-occlusion
#29
JOURNAL ARTICLE
Shuhao Li, Senyan Yang, Shujing Zhou, Shuang Zhang, Xueying Li, Haibo Zhang, Ping Ren, Yanwu Liu, Ying Liu, Yuanguo Chen
Takotsubo syndrome (TTS), commonly referred to as "broken heart syndrome," is a distinctive form of acute and reversible heart failure that primarily affects young to middle-aged individuals, particularly women. While emotional or physical stressors often trigger TTS, rare cases have been linked to interventional procedures for congenital heart disease (CHD). Despite its recognition, the exact causes of TTS remain elusive. Research indicates that dysregulation in autonomic nerve function, involving sympathetic and parasympathetic activities, plays a pivotal role...
March 2, 2024: BMC Cardiovascular Disorders
https://read.qxmd.com/read/38431145/comment-on-evaluation-of-brain-function-in-adult-patent-ductus-arteriosus-surgery-a-multimodal-monitoring-approach-by-qin-x-et-al
#30
REVIEW
Rabia Asim, Bazil Azeem, Mata-E-Alla Dogar
No abstract text is available yet for this article.
February 29, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38422726/transesophageal-echocardiography-using-a-microprobe-for-determination-of-transcatheter-procedural-candidacy-device-selection-and-procedural-monitoring-in-small-dogs-with-patent-ductus-arteriosus
#31
JOURNAL ARTICLE
S Wesselowski, A B Saunders
INTRODUCTION: Small dogs with patent ductus arteriosus (PDA) may be unable to undergo transesophageal echocardiography (TEE) with traditional probes. OBJECTIVES: To report the utility of TEE using a microprobe in dogs weighing less than 4 kg diagnosed with PDA for determination of transcatheter procedural candidacy, device selection, and intraoperative procedural guidance. ANIMALS: Eight dogs weighing less than 4 kg diagnosed with PDA...
February 8, 2024: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
https://read.qxmd.com/read/38418993/factors-influencing-necrotizing-enterocolitis-in-premature-infants-in-china-a-systematic-review-and-meta-analysis
#32
JOURNAL ARTICLE
Shuliang Zhao, Huimin Jiang, Yiqun Miao, Wenwen Liu, Yanan Li, Hui Liu, Aihua Wang, Xinghui Cui, Yuanyuan Zhang
BACKGROUND: Necrotizing enterocolitis (NEC) is a multifactorial gastrointestinal disease with high morbidity and mortality among premature infants. However, studies with large samples on the factors of NEC in China have not been reported. This meta-analysis aims to systematically review the literature to explore the influencing factors of necrotizing enterocolitis in premature infants in China and provide a reference for the prevention of NEC. METHODS: PubMed, Embase, Web of Science, Cochrane Library, China National Knowledge Infrastructure (CNKI), China Biomedical Literature Database (CBM), Wanfang and VIP databases were systematically searched from inception to February 2023...
February 29, 2024: BMC Pediatrics
https://read.qxmd.com/read/38412515/differential-clubbing-and-a-triad-of-patent-ductus-arteriosus-ventricular-septal-defect-and-supravalvular-ring-mitral-stenosis-a-case-report
#33
C O Osagie, O S Ogah, A Aje, A A Adebiyi, A M Adeoye, O O Oladapo, B E Adebayo
It is not uncommon for congenital heart defects to occur in clusters. Those involving a right to left heart shunt commonly cause cyanosis and finger clubbing. Differential clubbing involving only the lower limb digits is a strong pointer to the presence of patent ductus arteriosus with reversal of shunt. We report a case of 25-year-old man with effort intolerance and differential clubbing. He was found to have the uncommon triad of patent ductus arteriosus, ventricular septal defect and supravalvular ring mitral stenosis...
January 31, 2024: West African Journal of Medicine
https://read.qxmd.com/read/38401790/screening-for-delayed-thyroid-stimulation-hormone-rise-and-atypical-congenital-hypothyroidism-in-infants-born-very-preterm-and-very-low-birth-weight-infants
#34
JOURNAL ARTICLE
Nolan Bret, Uy Cherry, Stablein Lisa, Bany-Mohammed Fayez
OBJECTIVE: To determine among infants born very preterm (VPT) or with very low birth weight (VLBW) the incidence of alterations in thyroid function and associated co-morbidities; the incidence of atypical congenital hypothyroidism (CH) requiring thyroxine therapy; and 3) reference ranges for re-screening at one month of age. STUDY DESIGN: A retrospective review of infants born VPT or with VLBW and admitted to UCI Medical Center between 1/1/2012 and 12/31/2020. Repeat thyroid screening was obtained at 1 month of life (+ 10 days)...
February 22, 2024: Journal of Pediatrics
https://read.qxmd.com/read/38394548/perioperative-care-of-neonates-with-critical-pulmonary-stenosis-case-report
#35
JOURNAL ARTICLE
Qiong He, Min Song, Yanping Huang, Ling Wan
RATIONALE: Summarizing the perioperative nursing experience in the successful treatment of 4 neonates with critical pulmonary stenosis (CPS). PATIENT CONCERNS: Of the 4 patients, 3 had postnatal shortness of breath and varying degrees of cyanosis, aggravated by crying and noise, and 1 had no obvious shortness of breath and cyanosis. The preoperative auscultation of the precordial region could be heard 3-4/6 systolic murmur; echocardiography was diagnosed as CPS, combined with patent ductus arteriosus, right ventricular dysplasia, and severe tricuspid regurgitation...
February 23, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38393925/serum-pentraxin-3-levels-in-term-neonates-with-persistent-pulmonary-hypertension
#36
JOURNAL ARTICLE
A E A Asal, Z F Oshaiba, E N A Mansour, O H Abd Elaziz, A A A Nasr
BACKGROUND: Persistent pulmonary hypertension of the neonate (PPHN) is a serious disorder. The long pentraxin 3 (PTX3) plays an important role in angiogenesis, cell proliferation, tissue repair and cell regulation. The present study aims to assess the diagnostic and clinical value of PTX3 in PPHN. METHODS: The present case-control 60 full-term neonates diagnosed with PPHN by echocardiography within 72 hours of birth. In addition, there were 30 age and sex-matched healthy neonates who served as controls...
2024: Journal of Neonatal-perinatal Medicine
https://read.qxmd.com/read/38388286/risk-factors-for-preoperative-pneumothorax-in-neonates-with-isolated-left-sided-congenital-diaphragmatic-hernia-an-international-cohort-study
#37
JOURNAL ARTICLE
Kazunori Masahata, Kouji Nagata, Keita Terui, Takuya Kondo, Ashley H Ebanks, Matthew T Harting, Terry L Buchmiller, Yasunori Sato, Hiroomi Okuyama, Noriaki Usui
BACKGROUND: We aimed to investigate the clinical characteristics and outcomes of patients with isolated left-sided congenital diaphragmatic hernia (CDH) who developed preoperative pneumothorax and determine its risk factors. METHODS: We performed an international cohort study of patients with CDH enrolled in the Congenital Diaphragmatic Hernia Study Group registry between January 2015 and December 2020. The main outcomes assessed included survival to hospital discharge and preoperative pneumothorax development...
January 29, 2024: Journal of Pediatric Surgery
https://read.qxmd.com/read/38385619/lung-ultrasound-score-in-the-decision-of-patent-ductus-arteriosus-closure-in-neonates
#38
JOURNAL ARTICLE
Mustafa Ozdemir, Tugay Tepe, Ferda Ozlu, Hacer Yapicioglu, Anıl Atmıs, Fadli Demir, Ilker Unal, Nejat Narli
PURPOSE: We aimed to investigate the role of lung ultrasound (LUS) score in the closure of hemodynamically insignificant patent ductus arteriosus (PDA) and the clinical findings of the patients before and after closure. METHODS: The study groups (107 preterm neonates under 34 gestational weeks) were classified as hemodynamically significant PDA (group 1), hemodynamically insignificant PDA with closure therapy (group 2), hemodynamically insignificant PDA without closure therapy (group 3), and no PDA group (group 4) based on the echocardiography...
February 22, 2024: Journal of Clinical Ultrasound: JCU
https://read.qxmd.com/read/38381375/post-ligation-cardiac-syndrome-after-surgical-versus-transcatheter-closure-of-patent-ductus-arteriosus-in-low-body-weight-premature-infants-a-multicenter-retrospective-cohort-study
#39
JOURNAL ARTICLE
Pierre-Marie Duboue, Paul Padovani, Xavier Paul Bouteiller, Frédérique Martin-Kabore, Nadir Benbrik, Céline Grunenwald Gronier, Antoine Bouissou, Elodie Garnier, Delphine Mitanchez, Cyril Flamant, Jean-Christophe Rozé, Alban-Elouen Baruteau, Bruno Lefort
Transcatheter patent ductus arteriosus (PDA) closure is a safe and effective alternative to surgical ligation in low-body-weight infants. Post-ligation cardiac syndrome (PLCS) is defined as severe hemodynamic and respiratory collapse within 24 h of PDA closure, requiring initiation or an increase of an inotropic agent by > 20% of preligation dosing and an absolute increase of at least 20% in ventilation parameters compared with the preoperative value. Whilst PLCS is routinely observed after surgery, its incidence remains poorly described following transcatheter closure...
February 21, 2024: European Journal of Pediatrics
https://read.qxmd.com/read/38379909/should-we-eliminate-pda-shunt-in-preterm-infants-a-narrative-review
#40
REVIEW
Aimann Surak, Amneet Sidhu, Joseph Y Ting
The patent ductus arteriosus frequently poses a significant morbidity in preterm infants, subjecting their immature pulmonary vascular bed to substantial volume overload. This, in turn, results in concurrent hypoperfusion to post-ductal organs, and subsequently alters cerebral blood flow. In addition, treatment has not demonstrated definitive improvements in patient outcomes. Currently, the optimal approach remains a subject of considerable debate with ongoing research controversy regarding the best approach...
2024: Frontiers in Pediatrics
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