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https://www.readbyqxmd.com/read/29458198/adverse-childhood-experiences-and-adult-inflammation-findings-from-the-1958-british-birth-cohort
#1
Mingyi Chen, Rebecca E Lacey
BACKGROUND: The relationship between adverse childhood experiences (ACE) and poorer health across the life course is well established. Increased chronic inflammation might be one mechanism through which these associations operate. The aim of this study was to explore the relationship between ACE and adult inflammation using a prospective longitudinal study. We also investigated whether associations were explained by life course socioeconomic, psychological and health behavioural factors, and whether associations differed by gender...
February 16, 2018: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/29453197/paediatric-hospital-admission-processes-and-outcomes-a-qualitative-study-of-parents-experiences-and-priorities
#2
JoAnna K Leyenaar, Paul A Rizzo, Emily R O'Brien, Peter K Lindenauer
BACKGROUND: Hospital admission, like hospital discharge, represents a transition of care associated with changes in setting, healthcare providers and clinical management. While considerable efforts have focused on improving the quality and safety of hospital-to-home transitions, there has been little focus on transitions into hospital. OBJECTIVES: Among children hospitalised with ambulatory care sensitive conditions, we aimed to characterise families' experiences as they transitioned from outpatient to inpatient care, identify hospital admission processes and outcomes most important to families and determine how parental perspectives differed between children admitted directly and through emergency departments (ED)...
February 16, 2018: BMJ Quality & Safety
https://www.readbyqxmd.com/read/29452789/informal-caregiving-and-metabolic-markers-in-the-uk-household-longitudinal-study
#3
Rebecca E Lacey, Anne McMunn, Elizabeth A Webb
OBJECTIVES: Informal caregiving is associated with poorer mental and physical health. Little research has yet focused on objectively measured health risk factors, such as metabolic markers. The aim of this study was to investigate whether informal caregiving was associated with markers of metabolism in a large, representative UK longitudinal study. We also investigated whether more intensive caregiving, as indicated by more caregiving hours, was associated with a less favourable metabolic profile...
March 2018: Maturitas
https://www.readbyqxmd.com/read/29450764/impact-of-well-being-interventions-for-siblings-of-children-and-young-people-with-a-chronic-physical-or-mental-health-condition-a-systematic-review-and-meta-analysis
#4
REVIEW
Mhairi McKenzie Smith, Snehal Pinto Pereira, Lynette Chan, Charlotte Rose, Roz Shafran
Siblings of children and young people with a chronic illness are at increased risk of poor psychological functioning. A number of studies have attempted to implement and evaluate interventions targeting the psychological well-being of this at-risk group. This systematic review summarises the evidence regarding psychological functioning of siblings following an intervention targeting their well-being. The meta-analysis considered behaviour and knowledge, two of the most frequently studied outcomes. The following databases were used: PsycINFO, EMBASE, CINAHL, PubMed, Scopus and Web of Science...
February 15, 2018: Clinical Child and Family Psychology Review
https://www.readbyqxmd.com/read/29448936/chitinase-3-like-1-is-a-biomarker-of-acute-kidney-injury-and-mortality-in-paediatric-severe-malaria
#5
Andrea L Conroy, Michael T Hawkes, Robyn Elphinstone, Robert O Opoka, Sophie Namasopo, Christopher Miller, Chandy C John, Kevin C Kain
BACKGROUND: Chitinase-3-like 1 (CHI3L1) is a glycoprotein elevated in paediatric severe malaria, and an emerging urinary biomarker of acute kidney injury (AKI). Based on the hypothesis that elevated CHI3L1 levels in malaria are associated with disease severity, the relationship between plasma CHI3L1 levels, AKI and mortality was investigated in Ugandan children enrolled in a clinical trial evaluating inhaled nitric oxide (iNO) as an adjunctive therapy for severe malaria. METHODS: Plasma CHI3L1 levels were measured daily for 4 days in children admitted to hospital with severe malaria and at day 14 follow up...
February 15, 2018: Malaria Journal
https://www.readbyqxmd.com/read/29447897/pattern-of-allergic-rhinitis-among-children-in-ekiti-nigeria
#6
Waheed Atilade Adegbiji, Gabriel Toye Olajide, Anthony Oyebanji Olajuyin, Shuaib Kayode Aremu, Akanbi Ganiyu Olusola
BACKGROUND: Allergic rhinitis is a chronic and recurrent nasal condition. It is often neglected in children with late presentation. This study aimed at determining the prevalence, sociodemographic features, comorbid illnesses, complications and quality of life in children with allergic rhinitis in the study institution. MATERIALS AND METHODS: This is a prospective hospital based study of children with allergic rhinitis in Ekiti state university teaching hospital, Ado Ekiti...
March 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29447223/virome-and-bacteriome-characterization-of-children-with-pneumonia-and-asthma-in-mexico-city-during-winter-seasons-2014-and-2015
#7
Jose A Romero-Espinoza, Yazmin Moreno-Valencia, Rodrigo H Coronel-Tellez, Manuel Castillejos-Lopez, Andres Hernandez, Aaron Dominguez, Angel Miliar-Garcia, Arturo Barbachano-Guerrero, Rogelio Perez-Padilla, Alejandro Alejandre-Garcia, Joel A Vazquez-Perez
BACKGROUND: Acute asthma exacerbations and pneumonia are important causes of morbidity and mortality in children and may coexist in the same children, although symptom overlap may lead to difficulties in diagnosis. Microbial and viral diversity and differential abundance of either may play an important role in infection susceptibility and the development of acute and chronic respiratory diseases. OBJECTIVES: To describe the virome and bacteriome present in the upper respiratory tract of hospitalized children with a clinical diagnosis of asthma and pneumonia during an acute exacerbation and an acute respiratory illness ARI episode respectively...
2018: PloS One
https://www.readbyqxmd.com/read/29444686/cumulative-incidence-distribution-and-determinants-of-catastrophic-health-expenditure-in-nepal-results-from-the-living-standards-survey
#8
Mamata Ghimire, Rakesh Ayer, Masahide Kondo
BACKGROUND: Nepal has committed to the global community to achieve universal health coverage by 2030. Nevertheless, Nepal still has a high proportion of out-of-pocket health payment and a limited risk-pooling mechanism. Out-of-pocket payment for the healthcare services could result in catastrophic health expenditure (CHE). Evidence is required to effectively channel the efforts to lower those expenses in order to achieve universal health coverage. However, little is known about CHE and its determinants in a broad national context in Nepal...
February 14, 2018: International Journal for Equity in Health
https://www.readbyqxmd.com/read/29438452/early-life-predictors-of-future-multi-morbidity-results-from-the-hertfordshire-cohort
#9
Jenny Humphreys, Karen Jameson, Cyrus Cooper, Elaine Dennison
Background: multi-morbidity is an increasing challenge in western medicine and has the potential to impact patients' quality of life, treatment options and compliance with medications. The aim of this study was to identify the early-life predictors of long-term multi-morbidity in an historical cohort, the Hertfordshire Cohort Study (HCS). Methods: perinatal and infant health records were kept on all children born in Hertfordshire between 1931 and 1939. Participants who were still alive in 1998 were recruited to the HCS and data collected on major chronic diseases...
February 9, 2018: Age and Ageing
https://www.readbyqxmd.com/read/29436011/improving-disease-knowledge-in-6-to-10-year-olds-with-sickle-cell-disease-a-quasi-experimental-study
#10
N Morrison-Levy, J Knight-Madden, T Royal-Thomas, L King, M Asnani
BACKGROUND: Increasing knowledge and understanding of disease is known to improve outcomes in persons living with a chronic illness. In this paper, we aim to compare the disease knowledge of children with sickle cell disease (SCD), age 6-10 years, who received an intervention (an educational colouring book on SCD) geared towards improving disease knowledge, to those who did not received the colouring book. METHODS: A quasi-experimental study was conducted where disease knowledge was determined in 56 children who had received the colouring book and compared to 60 children who did not receive this intervention...
February 12, 2018: Child: Care, Health and Development
https://www.readbyqxmd.com/read/29433666/similarities-and-differences-in-child-development-from-birth-to-age-3-years-by-sex-and-across-four-countries-a-cross-sectional-observational-study
#11
Ilgi Ozturk Ertem, Vibha Krishnamurthy, Mphelekedzeni C Mulaudzi, Yanina Sguassero, Hakan Balta, Ozlem Gulumser, Burcu Bilik, Roopa Srinivasan, Benjamin Johnson, Geliang Gan, Lisa Calvocoressi, Veronika Shabanova, Brian W C Forsyth
BACKGROUND: Knowledge about typical development is of fundamental importance for understanding and promoting child health and development. We aimed to ascertain when healthy children in four culturally and linguistically different countries attain developmental milestones and to identify similarities and differences across sexes and countries. METHODS: In this cross-sectional, observational study, we recruited children aged 0-42 months and their caregivers between March 3, 2011, and May 18, 2015, at 22 health clinics in Argentina, India, South Africa, and Turkey...
March 2018: Lancet Global Health
https://www.readbyqxmd.com/read/29427120/challenges-in-transition-of-care-for-pediatric-patients-after-weight-reduction-surgery-a-systematic-review-and-recommendations-for-comprehensive-care
#12
REVIEW
Sarah B Cairo, Indrajit Majumdar, Aurora Pryor, Alan Posner, Carroll M Harmon, David H Rothstein
Obesity in pediatric patients is rising with nearly one third of children in the USA classified as overweight and up to 16-18% of the adolescent population obese with at least one comorbid condition. Consequently, bariatric procedures in this population have increased without consistent recommendations for follow-up and transition to adult providers. This review describes the known and potential long-term consequences of bariatric surgery in pediatric patients, reviews the current literature on transitions of care for adolescent patients with chronic illnesses...
February 9, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/29415750/acute-malnutrition-among-children-aged-6-59%C3%A2-months-of-the-nomadic-population-in-hadaleala-district-afar-region-northeast-ethiopia
#13
Zemichael Gizaw, Wondwoson Woldu, Bikes Destaw Bitew
BACKGROUND: Acute malnutrition to be a major health burden in the world, particularly in the developing world. Acute malnutrition is associated with more than one third of the global disease burden for children. Malnourished children are physically, emotionally and intellectually less productive and suffer more from chronic illnesses and disabilities. The nature, magnitude and determinants of acute malnutrition are determined among the general populations; however, there is a lack of evidence in the nomadic communities...
February 7, 2018: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/29414028/relation-of-long-term-patterns-in-caregiving-activity-and-depressive-symptoms-to-telomere-length-in-older-women
#14
Shun-Chiao Chang, Marta Crous-Bou, Jennifer Prescott, Bernard Rosner, Naomi M Simon, Wei Wang, Immaculata De Vivo, Olivia I Okereke
BACKGROUND: Research links psychological stress to accelerated cellular aging. Here we examined whether long-term patterns of depression and caregiving burden, forms of chronic psychological stress, were associated with shorter telomere length, a biomarker of cellular aging. METHODS: The study included 1250 healthy older women (mean: 68.0; range: 60-81 years) in the Nurses' Health Study. Long-term patterns in depressive symptoms and caregiving activity (separated into care of children/grandchildren vs...
January 9, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29412394/biographical-ruptures-and-flows-in-the-family-experience-and-trajectory-of-children-with-cystic-fibrosis
#15
Marcelo Eduardo Pfeiffer Castellanos, Nelson Filice de Barros, Sandra Straccialano Coelho
Biographical disruption (BD) became a core concept of sociological studies on the chronic illness experience by showing how this event can be strongly affected by ruptures in the ways of living and organizing the biographical trajectory through narratives. Critical reviews have pointed out that the widespread use of this concept was not sufficiently attentive to its analytical limits, e.g. addressing experiences of children with genetic diseases, when biographic flows (BF) rather than BD would be probably found...
February 2018: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/29402762/effect-on-the-metabolic-biomarkers-in-schoolchildren-after-a-comprehensive-intervention-using-electronic-media-and-in-person-sessions-to-change-lifestyles-community-trial
#16
Jenny Vilchis-Gil, Miguel Klünder-Klünder, Samuel Flores-Huerta
BACKGROUND: Obesity is a chronic low-intensity state of inflammation with metabolic alterations that, when acquired during childhood, lead to severe illness in adults. Encouraging healthy eating habits and physical activity is the basis for preventing and treating obesity and its complications. OBJECTIVE: To evaluate how a comprehensive intervention promoting healthy eating habits and physical activities in schools affects children's metabolic biomarkers. METHODS: Of four Mexico City primary schools in this study, two groups of children that were recruited at their schools were assigned to a 12-month intervention group (IG) and the other two were assigned to control groups (CGs)...
February 5, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29399910/mothers-experience-of-caring-for-a-child-with-early-onset-scoliosis-a-qualitative-descriptive-study
#17
Bonnie Lauder, Peter Sinclair, Jane Maguire
BACKGROUND: Chronic childhood disease has a major impact on health related quality of life. Caring for a child with a chronic illness is well documented but the specific experiences of parents who care for children with Early Onset Scoliosis (EOS), a rare but devastating illness, has not been explored. Numerous studies have described the interrelated psychological, financial, social, physical and logistical factors that impact on the experience of the care giver role with various diseases, but in the case of EOS, limited studies have been conducted about the parental experience...
February 5, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29396310/parent-s-perspectives-on-how-they-cope-with-the-impact-on-their-family-of-a-child-with-heart-disease
#18
Alun C Jackson, Rosemary O Higgins, Erica Frydenberg, Rachel P-T Liang, Barbara M Murphy
PURPOSE: Studies of familial coping with a child's chronic condition have highlighted psychological distress; family functioning; and quality of life; as issues that demand coping strategies. There are conflicting findings on impact and coping and a paucity of information about the specific coping challenges for parents of a child with heart disease, with few qualitative studies in this area. The purpose of the study was to explore the way parents coped with their child's heart condition as it impacted on different domains of family functioning...
January 31, 2018: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29392748/preliminary-validation-of-a-self-efficacy-scale-for-pediatric-chronic-illness
#19
N D Emerson, H E R Morrell, N Mahtani, L Sanderson, C Neece, K C Boyd, B Distelberg
BACKGROUND: Tracking self-efficacy may be useful for identifying children at risk for medical noncompliance. We created the Pediatric Rating of Chronic Illness Self-Efficacy (PRCISE) to measure self-efficacy in youth dealing with a chronic illness. METHOD: Data were collected from 217 families where one child aged 7-20 (Mage  = 13.62, SDage  = 2.92; 62.7% Latino, 58.1% female) had a chronic illness. Parent participants provided demographic information. Youth completed a depression measure, the Patient Health Questionnaire for Adolescents and the PRCISE...
February 1, 2018: Child: Care, Health and Development
https://www.readbyqxmd.com/read/29391704/correlation-of-salivary-glucose-level-with-blood-glucose-level-in-diabetes-mellitus
#20
Shreya Gupta, Meghanand T Nayak, J D Sunitha, Geetanshu Dawar, Nidhi Sinha, Neelakshi Singh Rallan
Background: Saliva is a unique fluid, which is important for normal functioning of the oral cavity. Diabetes mellitus (DM) is a disease of absolute or relative insulin deficiency characterized by insufficient secretion of insulin by pancreatic beta-cells. The diagnosis of diabetes through blood is difficult in children, older adults, debilitated and chronically ill patients, so diagnosis by analysis of saliva can be potentially valuable as collection of saliva is noninvasive, easier and technically insensitive, unlike blood...
September 2017: Journal of Oral and Maxillofacial Pathology: JOMFP
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