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https://www.readbyqxmd.com/read/27888862/functional-and-motor-gastrointestinal-disorders
#1
Fermín Mearin, Enrique Rey, Agustín Balboa
This article discusses the most interesting presentations at Digestive Disease Week, held in San Diego, in the field of functional and motor gastrointestinal disorders. One of the most important contributions was undoubtedly the presentation of the new Rome IV diagnostic criteria for functional gastrointestinal disorders. We therefore devote some space in this article to explaining these new criteria in the most common functional disorders. In fact, there has already been discussion of data comparing Rome IV and Rome III criteria in the diagnosis of irritable bowel syndrome, confirming that the new criteria are somewhat more restrictive...
September 2016: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/27398981/neurorehabilitation-strategies-for-poststroke-oropharyngeal-dysphagia-from-compensation-to-the-recovery-of-swallowing-function
#2
Christopher Cabib, Omar Ortega, Hatice Kumru, Ernest Palomeras, Natalia Vilardell, Daniel Alvarez-Berdugo, Desirée Muriana, Laia Rofes, Rosa Terré, Fermín Mearin, Pere Clavé
Oropharyngeal dysphagia (OD) is very prevalent among poststroke patients, causing severe complications but lacking specific neurorehabilitation treatment. This review covers advances in the pathophysiology, diagnosis, and physiologically based neurorehabilitation strategies for poststroke OD. The pathophysiology of oropharyngeal biomechanics can be assessed by videofluoroscopy, as delayed laryngeal vestibule closure is closely associated with aspiration. Stroke may affect afferent or efferent neuronal circuits participating in deglutition...
July 11, 2016: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/27342080/iv-spanish-consensus-conference-on-helicobacter-pylori-infection-treatment
#3
Javier P Gisbert, Javier Molina-Infante, Javier Amador, Fernando Bermejo, Luis Bujanda, Xavier Calvet, Manuel Castro-Fernández, Antonio Cuadrado-Lavín, J Ignasi Elizalde, Emili Gene, Fernando Gomollón, Ángel Lanas, Carlos Martín de Argila, Fermín Mearin, Miguel Montoro, Ángeles Pérez-Aisa, Emilio Pérez-Trallero, Adrián G McNicholl
Helicobacter pylori approximately infect 50% of Spanish population and causes chronic gastritis, peptic ulcer and gastric cancer. Until now, three consensus meetings on H.pylori infection had been performed in Spain (the last in 2012). The changes in the treatment schemes, and the increasing available evidence, have justified organizing the IVSpanish Consensus Conference (March 2016), focused on the treatment of this infection. Nineteen experts participated, who performed a systematic review of the scientific evidence and developed a series of recommendation that were subjected to an anonymous Delphi process of iterative voting...
December 2016: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/27230827/clinical-practice-guideline-irritable-bowel-syndrome-with-constipation-and-functional-constipation-in-the-adult
#4
Fermín Mearin, Constanza Ciriza, Miguel Mínguez, Enrique Rey, Juan José Mascort, Enrique Peña, Pedro Cañones, Javier Júdez
In this Clinical Practice Guideline we discuss the diagnostic and therapeutic approach of adult patients with constipation and abdominal complaints at the confluence of the irritable bowel syndrome spectrum and functional constipation. Both conditions are included among the functional bowel disorders, and have a significant personal, healthcare, and social impact, affecting the quality of life of the patients who suffer from them. The first one is the irritable bowel syndrome subtype, where constipation represents the predominant complaint, in association with recurrent abdominal pain, bloating, and abdominal distension...
June 2016: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/27144627/bowel-disorders
#5
Fermín Mearin, Brian E Lacy, Lin Chang, William D Chey, Anthony J Lembo, Magnus Simren, Robin Spiller
Functional bowel disorders are highly prevalent disorders found worldwide. These disorders have the potential to affect all members of society, regardless of age, gender, race, creed, color or socioeconomic status. Improving our understanding of functional bowel disorders (FBD) is critical as they impose a negative economic impact to the global health care system in addition to reducing quality of life. Research in the basic and clinical sciences during the past decade has produced new information on the epidemiology, etiology, pathophysiology, diagnosis and treatment of FBDs...
February 18, 2016: Gastroenterology
https://www.readbyqxmd.com/read/26838485/irritable-bowel-syndrome-ibs-subtypes-nothing-resembles-less-an-ibs-than-another-ibs
#6
EDITORIAL
Fermín Mearin Manrique
Two new members of "IBS Patient Association" met at a meeting. Feeling somewhat lost, not knowing anybody present, they introduced themselves to each other. After exchanging names, one asks the other - "What's your problem?" The other one answers - "I got constipation that laxatives fail to relieve, and my belly, which is always bloated, sometimes hurts so much that I can´t even leave home". Deeply surprised, the first individual inquires - "What are you doing here then?" "Why, I came to this meeting looking for some help for my irritable colon", she answered...
February 2016: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/26797319/irritable-bowel-syndrome-ibs-subtypes-nothing-resembles-less-an-ibs-than-another-ibs
#7
Fermín Mearin Manrique
Two new members of "IBS Patient Association" met at a meeting. Feeling somewhat lost, not knowing anybody present, they introduced themselves to each other. After exchanging names, one asks the other - "What's your problem?" The other one answers - "I got constipation that laxatives fail to relieve, and my belly, which is always bloated, sometimes hurts so much that I can´t even leave home". Deeply surprised, the first individual inquires - "What are you doing here then?" "Why, I came to this meeting looking for some help for my irritable colon", she answered...
January 22, 2016: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/26694926/ferric-carboxymaltose-reduces-transfusions-and-hospital-stay-in-patients-with-colon-cancer-and-anemia
#8
José Luis Calleja, Salvadora Delgado, Adolfo del Val, Antonio Hervás, José Luis Larraona, Álvaro Terán, Mercedes Cucala, Fermín Mearin
PURPOSE: The purpose of the study was to evaluate the efficacy of preoperative intravenous (IV) ferric carboxymaltose (FCM) administration vs. no-IV iron in colon cancer (CC) anemic patients undergoing elective surgery with curative intention. METHODS: This was a multicenter, observational study including two cohorts of consecutive CC anemic patients: the no-IV iron treatment group was obtained retrospectively while FCM-treated patients were recorded prospectively...
March 2016: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/26548734/the-low-fodmap-diet-for-irritable-bowel-syndrome-lights-and-shadows
#9
Javier Molina-Infante, Jordi Serra, Fernando Fernandez-Bañares, Fermín Mearin
Irritable bowel syndrome (IBS) affects 10-15% of the western population. Drug therapy for this entity has shown limited efficacy. The low Fermentable Oligo-, Di-, Monosaccharides And Polyols (FODMAP) diet has recently emerged as an effective intervention for reducing gastrointestinal symptoms in IBS. Currently, several mechanistic studies have proven the rational basis of carbohydrate restriction. In addition, high-quality evidence (prospective studies and randomized controlled trials) from a variety of countries supports the high effectiveness of a low-FODMAP diet for IBS symptoms (70%), especially abdominal bloating, pain, and diarrhea...
February 2016: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/26520191/-functional-and-motor-gastrointestinal-disorders
#10
Fermín Mearin, Enrique Rey, Agustín Balboa
This article discusses the most interesting studies on functional and motor gastrointestinal disorders presented at Digestive Diseases Week (DDW), 2015. Researchers are still seeking biomarkers for irritable bowel syndrome and have presented new data. One study confirmed that the use of low-dose antidepressants has an antinociceptive effect without altering the psychological features of patients with functional dyspepsia. A contribution that could have immediate application is the use of transcutaneous electroacupuncture, which has demonstrated effectiveness in controlling nausea in patients with gastroparesis...
September 2015: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/26409561/cost-minimization-analysis-favours-intravenous-ferric-carboxymaltose-over-ferric-sucrose-or-oral-iron-as-preoperative-treatment-in-patients-with-colon-cancer-and-iron-deficiency-anaemia
#11
Xavier Calvet, Emili Gené, Miquel ÀngelRuíz, Ariadna Figuerola, Albert Villoria, Mercedes Cucala, Fermín Mearin, Salvadora Delgado, Jose Luis Calleja
BACKGROUND: Ferric Carboxymaltose (FCM), Iron Sucrose (IS) and Oral Iron (OI) are alternative treatments for preoperative anaemia. OBJECTIVE: To compare the cost implications, using a cost-minimization analysis, of three alternatives: FCM vs. IS vs. OI for treating iron-deficient anaemia before surgery in patients with colon cancer. METHODS: Data from 282 patients with colorectal cancer and anaemia were obtained from a previous study. One hundred and eleven received FCS, 16 IS and 155 OI...
2016: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/25294261/-motility-and-functional-gastrointestinal-disorders
#12
Fermín Mearin, Enrique Rey, Agustín Balboa
This article discusses the studies on functional and motor gastrointestinal disorders presented at the 2014 Digestive Diseases Week conference that are of greatest interest to us. New data have been provided on the clinical importance of functional gastrointestinal disorders, with recent prevalence data for irritable bowel syndrome and fecal incontinence. We know more about the pathophysiological mechanisms of the various functional disorders, especially irritable bowel syndrome, which has had the largest number of studies...
September 2014: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/24667349/serum-alanine-aminotransferase-predicts-interventricular-septum-thickness-and-left-ventricular-mass-in-patients-with-nonalcoholic-fatty-liver-disease
#13
Juan Ybarra, Sandra Fernández, Joan Sánchez-Hernández, June H Romeo, Carlos Ballesta-Lopez, Javier Guell, Fermin Mearin
BACKGROUND: Alanine aminotransferase (ALT) is a marker of nonalcoholic fatty liver disease (NAFLD) and predicts type 2 diabetes mellitus (DM2) as well as coronary events independently of traditional risk factors and the features of the metabolic syndrome. The extent to which interventricular septum thickness (IVS) and left ventricular mass (LVM) are associated with ALT levels in cohorts of individuals with body weights ranging from overweight to morbid obesity and NAFLD remains still unknown...
June 2014: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/24589666/chronic-constipation-irritable-bowel-syndrome-with-constipation-and-constipation-with-pain-discomfort-similarities-and-differences
#14
COMMENT
Enrique Rey, Agustín Balboa, Fermín Mearin
OBJECTIVES: Some patients with chronic constipation (CC) have abdominal pain and discomfort (painful CC) without fulfilling the criteria for irritable bowel syndrome (IBS). Our aim was to investigate similarities and differences among nonpainful CC, painful CC, and CC in patients with IBS according to prevalence, individual symptoms, associated factors, and impact on health-related quality of life and use of medical resources. METHODS: We conducted a telephone survey of a random sample of the Spanish population (N=1500)...
June 2014: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/24582764/-importance-of-diet-in-irritable-bowel-syndrome
#15
Fermín Mearin, Enrique Peña, Agustín Balboa
About two-thirds of irritable bowel syndrome (IBS) patients associate their symptoms with certain foods. We reviewed food-related factors putatively associated with manifestations of IBS. Soluble fiber may improve constipation but frequently increases bloating and abdominal pain. Carbohydrate malabsorption seems to be more frequent in IBS. A low FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides and polyols) diet significantly reduces IBS symptoms and has been suggested as a therapeutic option...
May 2014: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/24160947/-functional-and-motor-digestive-disorders
#16
Fermín Mearin, Enrique Rey, Agustín Balboa
This article discusses the most interesting studies on functional and motility gastrointestinal disorders presented in Digestive Diseases Week (DDW) in 2013. New data were reported on the clinical importance of functional gastrointestinal disorders (FGID) and on how they can produce numerous disturbances such as inflammatory bowel disease. These disturbances are associated with somatic functional disease and particularly with fatigue. In addition, new data have emerged on the physiopathology of these disorders, with some studies reporting that environmental factors and events in early infancy can favor their development...
October 2013: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/24100539/anaemia-management-in-patients-with-inflammatory-bowel-disease-routine-practice-across-nine-european-countries
#17
MULTICENTER STUDY
Jürgen Stein, Palle Bager, Ragnar Befrits, Christoph Gasche, Maja Gudehus, Eric Lerebours, Fernando Magro, Fermin Mearin, Daniell Mitchell, Bas Oldenburg, Silvio Danese
BACKGROUND AND OBJECTIVES: Anaemia and iron deficiency (ID) are common complications in inflammatory bowel disease (IBD). In patients undergoing iron therapy, intravenous iron supplementation is recommended in preference to oral therapy. This study evaluated routine practice in the management of IBD-associated anaemia and ID to verify implementation of international treatment guidelines. MATERIALS AND METHODS: Gastroenterologists from nine European countries (n=344) were surveyed about their last five IBD patients treated for anaemia (n=1404)...
December 2013: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/24029448/-irritable-bowel-syndrome-celiac-disease-and-gluten
#18
REVIEW
Fermín Mearin, Miguel Montoro
For many years irritable bowel syndrome (IBS) and celiac disease (CD) have been considered 2 completely separate entities, with CD being clearly related to a permanent gluten intolerance and IBS having no relation with gluten ingestion. However IBS and CD symptoms may be indistinguishable, especially when diarrhea, bloating or abdominal pain predominate. In the last decade several studies have shown that the separation between CD and IBS is not so clear. Thus, some patients who have been diagnosed of IBS suffer in fact from CD...
August 4, 2014: Medicina Clínica
https://www.readbyqxmd.com/read/23972683/-prevalence-and-characteristics-of-anemia-and-iron-deficiency-in-patients-hospitalized-for-gastrointestinal-diseases-in-spain
#19
MULTICENTER STUDY
Fermín Mearin, Manuel Barreiro-de Acosta, Ángel González-Galilea, Javier P Gisbert, Mercedes Cucala, Julio Ponce
OBJECTIVE: To determine the prevalence and characteristics of anemia and iron deficiency in patients hospitalized for gastrointestinal diseases. METHODS: An epidemiological, multicenter, mixed design study (retrospective review of randomized clinical records and prospective visits) conducted between February 2010 and March 2011 in 22 Spanish gastroenterology departments. Severe anemia was defined as Hb < 10g/dL, mild/moderate as Hb ≥ 10g/dL, and iron deficiency as ferritin < 30ng/ml or transferrin saturation < 16%...
October 2013: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/23769426/-impact-of-chronic-constipation-on-quality-of-life-much-more-important-than-it-seems
#20
Fermín Mearin
Chronic constipation is highly frequent in the general population (a prevalence of 14%). An underlying organic cause is usually absent, this type of constipation being known as chronic idiopathic constipation (CIC). Although usually considered banal, this disorder has a substantial personal, social and healthcare impact. Several studies have associated CIC with high rates of absenteeism in the workplace and disruption of routine activities. All these factors lead to high direct and indirect healthcare expenditure...
August 2013: Gastroenterología y Hepatología
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