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pneumoconiosis vo2

I Duvenkamp, T T Bauer, E W Schmidt, B Emming, B Lemke, G Schultze-Werninghaus
Disabilities of patients with coal-workers' pneumoconiosis (CWP) are currently estimated by changes in lung function at rest and the degree of dust equivalents in chest x-ray (ILO-classification 1980). Functional disturbances during exercise are not taken into consideration on a regular basis. We assumed that standardised sub-maximal exercise tests might be useful even in disabled patients to give additional information on functional disabilities of patients with CWP. The impact of low-grade anthracosilicosis on ventilation and gas exchange during exercise was assessed in 20 patients (all male, age 64...
March 1998: Pneumologie
M L Harbison, J D Brain
The effects of exercise and its associated increase in ventilation on the deposition of inhaled particles were investigated. Both total retention and patterns of distribution of a 99mTc sulfur colloid aerosol (activity median aerodynamic diameter, 0.38 micron; geometric standard deviation, 1.35) were measured in male Syrian golden hamsters. Animals were either anesthetized, resting, or exercising on a treadmill during a 15-min aerosol exposure. Each hamster's oxygen consumption (VO2) was continuously monitored during the exposure; immediately after, the animal was killed...
November 1983: American Review of Respiratory Disease
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