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https://www.readbyqxmd.com/read/28637237/long-term-evolutionary-change-in-the-lumen-of-intracranial-atherosclerotic-stenosis-following-angioplasty-and-stenting
#1
Simon C H Yu, Tiffany W W Lau, Simon S M Wong, Kwok T Lee, Lawrence K S Wong, Thomas W H Leung
BACKGROUND: Angioplasty and stenting is a recognized treatment option for patients with intracranial atherosclerosis. OBJECTIVE: To evaluate the long-term evolutionary luminal changes of intracranial atherosclerosis after angioplasty and stenting. METHODS: This was a retrospective study with patient consent. Eighty-two patients presenting with acute and minor cerebral ischemia due to stenosis ≥70%, who had received medical therapy with or without stenting (Wingspan), were invited...
June 14, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28583043/intracranial-stenting-for-nilotinib-treatment-associated-cerebrovascular-stenosis-in-chronic-myeloid-leukemia
#2
Tomohiko Ozaki, Hajime Nakamura, Nobuyuki Izutsu, Hiroaki Masaie, Jun Ishikawa, Manabu Kinoshita
One of the second-generation tyrosine kinase inhibitors (TKIs), nilotinib, is increasingly used for imatinib-resistant or intolerant chronic myeloid leukemia (CML). Nilotinib is considered well tolerated with few side effects including hyperglycemia, hyperbilirubinemia and elevated levels of pancreatic enzymes. However, there is growing evidence that nilotinib accelerates atherosclerosis and causes peripheral arterial occlusive disease such as stroke, transient ischemic attack (TIA) and cardiovascular diseases...
January 1, 2017: Interventional Neuroradiology
https://www.readbyqxmd.com/read/28542053/monopoly-airplane-lands-in-esophagus-leading-to-difficult-extraction-a-case-report-on-anesthesia-and-surgical-considerations
#3
Clyde T Matava, Gaston Echaniz, William Parkes, Blake C Papsin, Evan J Propst, Sharon L Cushing
A 2-year-old child presented with an airplane game piece from the board game Monopoly lodged in her esophagus. The airplane's wings, engines, and winglets acted like fish hooks that entered the esophageal mucosa easily but were difficult to extract. Chest radiographs were used to estimate the airplane wingspan dimensions, and a Foley catheter was used to dilate the esophagus to allow foreign body extraction via rigid esophagoscopy with optical forceps. Deliberate deep placement of the endotracheal tube facilitated surgical manipulation...
May 23, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/28503484/prophylactic-dual-catheter-technique-to-prevent-side-branch-snowplowing-complications-during-angioplasty-and-stenting
#4
Leonard Ll Yeo, W M Wu, Y L Chen, C H Yeh, H F Wong
OBJECTIVE: Angioplasty and Stenting of intracranial atherosclerotic lesions have a higher complication rate and a large proportion of this is attributable to side branch arterial occlusion from forceful displacement of the atheroma into the ostia or snowplowing effect. This can result in severe disabilities when it result in small infarcts involving eloquent areas in the posterior circulation or the motor tracts. MATERIALS AND METHODS: We present a series of 6 cases utilizing a new dual catheter technique for maintaining the patency of at-risk vessels during angioplasty and stenting...
March 2017: Journal of Cerebrovascular and Endovascular Neurosurgery
https://www.readbyqxmd.com/read/28321414/medical-and-interventional-therapy-for-spontaneous-vertebral-artery-dissection-in-the-craniocervical-segment
#5
Guiyun Zhang, Zuoquan Chen
Background and Purpose. Spontaneous vertebral artery dissection (SVAD) is an important reason for posterior-circulation-ischemic stroke in the young and middle-aged population. Although some previous reports reveal a favorable outcome with conservative therapy, it is still controversial in the treatment of SVAD in some specific patients. Herein, we present our 10 years of clinical experience for SVAD at this location. Material and Methods. 20 patients with 20 SVADs in V2 and V3 segments were retrospectively studied...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28281465/an-experimental-comparative-study-of-the-efficiency-of-twisted-and-flat-flapping-wings-during-hovering-flight
#6
Hoang Vu Phan, Quang Tri Truong, Hoon Cheol Park
This work presents a parametric study to find a proper wing configuration for achieving economic flight by using unsteady blade element theory, which is based on the three-dimensional kinematics of a flapping wing. Power loading was first considered as a performance parameter for the study. The power loadings at each wing section along the wingspan were obtained for various geometric angles of attacks (AoAs) by calculating the ratios of the vertical forces generated and the powers consumed by that particular wing section...
March 10, 2017: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/28135222/predictive-validity-of-national-basketball-association-draft-combine-on-future-performance
#7
Masaru Teramoto, Chad L Cross, Randall H Rieger, Travis G Maak, Stuart E Willick
The National Basketball Association (NBA) Draft Combine is an annual event where prospective players are evaluated in terms of their athletic abilities and basketball skills. Data collected at the Combine should help NBA teams select right the players for the upcoming NBA Draft, however its value for predicting future performance of players has not been examined. This study investigated predictive validity of the NBA Draft Combine on future performance of basketball players. We performed a principal component analysis (PCA) on the 2010-2015 Combine data to reduce correlated variables (N = 234), a correlation analysis on the Combine data and future on-court performance to examine relationships (maximum pairwise N = 217), and a robust principal component regression (PCR) analysis to predict first-year and three-year on-court performance from the Combine measures (N = 148 and 127, respectively)...
January 20, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28133577/neck-biomechanics-indicate-that-giant-transylvanian-azhdarchid-pterosaurs-were-short-necked-arch-predators
#8
Darren Naish, Mark P Witton
Azhdarchid pterosaurs include the largest animals to ever take to the skies with some species exceeding 10 metres in wingspan and 220 kg in mass. Associated skeletons show that azhdarchids were long-necked, long-jawed predators that combined a wing planform suited for soaring with limb adaptations indicative of quadrupedal terrestrial foraging. The postcranial proportions of the group have been regarded as uniform overall, irrespective of their overall size, notwithstanding suggestions that minor variation may have been present...
2017: PeerJ
https://www.readbyqxmd.com/read/27988606/-i-andraca-i-i-yauichui-i-sp-n-a-new-species-endemic-to-mid-elevation-forests-of-taiwan-bombycidae-sensu-lato-lepidoptera
#9
Shipher Wu, Wei-Chun Chang
A new endemic, montane species of the genus Andraca, A. yauichui sp. nov., in Taiwan is described. It can be separated well from a lower montane, notable tea tree pest A. theae (Matsumura, 1909), based on morphological characters of adult, e.g. larger wingspan size, head vertex white rather than brown, valval apex truncate rather than bifurcate, and final instar larva, e.g. the presence of a pair of white spot on lateral part of each abdominal segment and a distinct short anal horn rather than the absence of two characters...
December 1, 2016: Zootaxa
https://www.readbyqxmd.com/read/27986847/mri-audit-of-complications-in-intracranial-stenosis-treated-with-wingspan-device
#10
Leonard L L Yeo, Y M Wu, Y L Chen, C H Yeh, T H Lee, H F Wong
OBJECTIVES: To evaluate the safety and efficacy of the Wingspan device for the treatment of symptomatic intracranial atherosclerotic stenosis (ICAS). METHODS: We audited a prospective ongoing database of consecutive patients who received Wingspan stenting between January 2013 and December 2015. All patients underwent MRI to audit any complications during the early follow-up period. We focused on the clinical demographics, lesion characteristics, treatment results, and periprocedural complications...
May 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/27960179/angioplasty-and-stenting
#11
REVIEW
Thomas W Leung, Ashley M Wabnitz, Zhongrong Miao, Marc I Chimowitz
The high rate of recurrent strokes in patients with intracranial atherosclerotic disease (ICAS) despite medical therapy prompted intracranial angioplasty and/or stenting an adjunctive treatment option. The minute calibers of cerebral arteries, the relative paucity of supporting medial and adventitia layers, the presence of end-anastomosing perforator branches, and the vascular tortuosity from groin to head all demand specialized operative skills and dedicated tools. Since the stroke mechanism of ICAS is diverse, patient selection for endovascular treatment requires a sound understanding of the underlying pathophysiology...
2016: Frontiers of Neurology and Neuroscience
https://www.readbyqxmd.com/read/27878078/cool-habitats-support-darker-and-bigger-butterflies-in-australian-tropical-forests
#12
Shuang Xing, Timothy C Bonebrake, Chin Cheung Tang, Evan J Pickett, Wenda Cheng, Sasha E Greenspan, Stephen E Williams, Brett R Scheffers
Morphology mediates the relationship between an organism's body temperature and its environment. Dark organisms, for example, tend to absorb heat more quickly than lighter individuals, which could influence their responses to temperature. Therefore, temperature-related traits such as morphology may affect patterns of species abundance, richness, and community assembly across a broad range of spatial scales. In this study, we examined variation in color lightness and body size within butterfly communities across hot and cool habitats in the tropical woodland-rainforest ecosystems of northeast Queensland, Australia...
November 2016: Ecology and Evolution
https://www.readbyqxmd.com/read/27853614/a-small-azhdarchoid-pterosaur-from-the-latest-cretaceous-the-age-of-flying-giants
#13
Elizabeth Martin-Silverstone, Mark P Witton, Victoria M Arbour, Philip J Currie
Pterosaur fossils from the Campanian-Maastrichtian of North America have been reported from the continental interior, but few have been described from the west coast. The first pterosaur from the Campanian Northumberland Formation (Nanaimo Group) of Hornby Island, British Columbia, is represented here by a humerus, dorsal vertebrae (including three fused notarial vertebrae), and other fragments. The elements have features typical of Azhdarchoidea, an identification consistent with dominance of this group in the latest Cretaceous...
August 2016: Royal Society Open Science
https://www.readbyqxmd.com/read/27738098/endovascular-reconstruction-of-internal-carotid-artery-dissection-in-patients-with-acute-ischemic-stroke-using-the-wingspan-stent
#14
Eduardo Murias Quintana, Pedro Vega Valdés, Edison Morales Deza, Alberto Gil Garcia, Hugo Cuellar Saenz, Alba L Salgado Bernal, María Cadenas Rodríguez, Lorena Benavente Fernández, Montserrat González Delgado, Nuria Riesco Pérez, Davinia Larrosa Campo, Sergio Calleja Puerta
OBJECTIVE: The purpose of this study is to demonstrate our experience in endovascular reconstruction of carotid dissections using the Wingspan Stent System™ (Boston Scientific, Natick, MA, USA), a device we use because of its high radial force and its navigation in extreme curves. METHODS: We treated 11 consecutive patients with acute ischemic stroke due to carotid dissection with the Wingspan stent, in the cervical carotid artery. RESULTS: Functional evaluation revealed that 10 of the 11 patients were independent at 3 months post surgery and that the 11 stents used were found to be patent at the 6-month follow-up digital subtraction angiography (DSA)...
December 2016: Interventional Neuroradiology
https://www.readbyqxmd.com/read/27707903/fruit-fly-scale-robots-can-hover-longer-with-flapping-wings-than-with-spinning-wings
#15
Elliot W Hawkes, David Lentink
Hovering flies generate exceptionally high lift, because their wings generate a stable leading edge vortex. Micro flying robots with a similar wing design can generate similar high lift by either flapping or spinning their wings. While it requires less power to spin a wing, the overall efficiency depends also on the actuator system driving the wing. Here, we present the first holistic analysis to calculate how long a fly-inspired micro robot can hover with flapping versus spinning wings across scales. We integrate aerodynamic data with data-driven scaling laws for actuator, electronics and mechanism performance from fruit fly to hummingbird scales...
October 2016: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/27667936/a-new-species-of-patania-from-the-hainan-island-china-lepidoptera-crambidae
#16
Dan Xu, Xi-Cui Du
Patania clava sp. n. is described from the Diaoluo Mountain of Hainan Island, China. The new species is distinguished from its most similar congener, Patania iopasalis (Walker, 1859), by the following features: wingspan 33.0-35.0 mm (vs. 21.0-30.0 mm), ventral cilia of the male antenna as long as the diameter of flagellomere (vs. 1/4), the thick finger-like gnathos (vs. the short broad sheet-like), a long thick needle-like cornutus stretching out from (vs. embedded in) a cluster of spicular cornuti near apex...
2016: ZooKeys
https://www.readbyqxmd.com/read/27528775/wake-structure-and-kinematics-in-two-insectivorous-bats
#17
Tatjana Y Hubel, Nickolay I Hristov, Sharon M Swartz, Kenneth S Breuer
We compare kinematics and wake structure over a range of flight speeds (4.0-8.2 m s(-1)) for two bats that pursue insect prey aerially, Tadarida brasiliensis and Myotis velifer Body mass and wingspan are similar in these species, but M. velifer has broader wings and lower wing loading. By using high-speed videography and particle image velocimetry of steady flight in a wind tunnel, we show that three-dimensional kinematics and wake structure are similar in the two species at the higher speeds studied, but differ at lower speeds...
September 26, 2016: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/27434674/ribosome%C3%A2-rela-structures-reveal-the-mechanism-of-stringent-response-activation
#18
Anna B Loveland, Eugene Bah, Rohini Madireddy, Ying Zhang, Axel F Brilot, Nikolaus Grigorieff, Andrei A Korostelev
Stringent response is a conserved bacterial stress response underlying virulence and antibiotic resistance. RelA/SpoT-homolog proteins synthesize transcriptional modulators (p)ppGpp, allowing bacteria to adapt to stress. RelA is activated during amino-acid starvation, when cognate deacyl-tRNA binds to the ribosomal A (aminoacyl-tRNA) site. We report four cryo-EM structures of E. coli RelA bound to the 70S ribosome, in the absence and presence of deacyl-tRNA accommodating in the 30S A site. The boomerang-shaped RelA with a wingspan of more than 100 Å wraps around the A/R (30S A-site/RelA-bound) tRNA...
2016: ELife
https://www.readbyqxmd.com/read/27387833/optimal-flapping-wing-for-maximum-vertical-aerodynamic-force-in-hover-twisted-or-flat
#19
Hoang Vu Phan, Quang Tri Truong, Thi Kim Loan Au, Hoon Cheol Park
This work presents a parametric study, using the unsteady blade element theory, to investigate the role of twist in a hovering flapping wing. For the investigation, a flapping-wing system was developed to create a wing motion of large flapping amplitude. Three-dimensional kinematics of a passively twisted wing, which is capable of creating a linearly variable geometric angle of attack (AoA) along the wingspan, was measured during the flapping motion and used for the analysis. Several negative twist or wash-out configurations with different values of twist angle, which is defined as the difference in the average geometric AoAs at the wing root and the wing tip, were obtained from the measured wing kinematics through linear interpolation and extrapolation...
2016: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/27324301/safety-and-efficacy-of-wingspan-stenting-for-severe-symptomatic-atherosclerotic-stenosis-of-the-middle-cerebral-artery-analysis-of-278-continuous-cases
#20
Ting Zhao, Wen-Yao Zhu, Xiao-Yi Xiong, Jie Li, Li Wang, Hui-Yan Ding, Fei Wei, Yu Zhou, Zi-Li Gong, Sai-Yu Cheng, Yong Liu, Jie Shuai, Qing-Wu Yang
OBJECTIVE: Our objective is to investigate the safety and long-term efficacy of the Wingspan stent (Boston Scientific, Natick, MA, USA) for treating severe atherosclerotic stenosis of the middle cerebral artery (MCA). METHODS: A total of 278 consecutive patients from our stroke database with clinical symptoms within the prior 90 days and intracranial atherosclerotic stenosis of 70% or above of the MCA were enrolled in this study between September 2012 and November 2014, and these patients were followed until the end of June 2015...
October 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
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