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https://www.readbyqxmd.com/read/28100253/minimally-invasive-percutaneous-osteosynthesis-versus-orif-for-sanders-type-ii-and-iii-calcaneal-fractures-a-prospective-randomized-intervention-trial
#1
Cong Jin, Dong Weng, Wanlei Yang, Wei He, Wengqing Liang, Yu Qian
BACKGROUND: This randomized controlled trial compared the clinical outcomes and complications of a novel minimally invasive percutaneous osteosynthesis (MIPO) with those of conventional treatment via an extended L-shaped lateral approach for calcaneal fractures. METHODS: Sixty-four patients with displaced intraarticular calcaneal fractures were enrolled. The patients were randomly allocated to receive either MIPO (29 patients) or open reduction and internal fixation via an extended L-shaped lateral approach (35 patients)...
January 18, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28099699/randomized-controlled-trial-comparing-operative-times-between-standard-and-robot-assisted-laparoscopic-hysterectomy
#2
Timothy A Deimling, Jennifer L Eldridge, Kristin A Riley, Allen R Kunselman, Gerald J Harkins
OBJECTIVE: To compare the operative time between robot-assisted laparoscopic hysterectomies and standard laparoscopic hysterectomies. METHODS: A prospective, randomized controlled trial enrolled women aged 18-80 years attending Penn State Hershey Medical Center between April 23 and October 20, 2014 to undergo hysterectomy. Participants were randomized using a random number generator to undergo either robot-assisted or standard laparoscopic hysterectomy. The primary outcome was the total operative time (surgeon incision to surgeon stop, including robot docking time, if applicable)...
January 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28096573/prolonged-patient-emergence-time-among-clinical-anesthesia-resident-trainees
#3
L McLean House, Nathan H Calloway, Warren S Sandberg, Jesse M Ehrenfeld
BACKGROUND AND AIMS: Emergence time, or the duration between incision closure and extubation, is costly nonoperative time. Efforts to improve operating room efficiency and identify trainee progress make such time intervals of interest. We sought to calculate the incidence of prolonged emergence (i.e., >15 min) for patients under the care of clinical anesthesia (CA) residents. We also sought to identify factors from resident training, medical history, anesthetic use, and anesthesia staffing, which affect emergence...
October 2016: Journal of Anaesthesiology, Clinical Pharmacology
https://www.readbyqxmd.com/read/28092335/distribution-pattern-of-the-superior-and-the-inferior-labial-arteries-impact-for-safe-upper-and-lower-lip-augmentation-procedures
#4
Cotofana Sebastian, Pretterklieber Bettina, Lucius Runhild, Frank Konstantin, Haas Maximilian, Schenck L Thilo, Gleiser Corinna, Weyers Imke, Wedel Thilo, Pretterklieber Michael
BACKGROUND: Understanding the precise position and course of the superior and inferior labial arteries within the upper and the lower lip is crucial for safe and complication free applications of volumizing materials. METHODS: 193 anatomic head specimens (56.5% females) of Caucasian ethnicity were investigated in this large multi-centric anatomical study. In total six 3cm long vertical incisions were performed on each lip (midline and 1cm medial to the angles of the mouth) to identify the position of the superior and the inferior labial arteries in relation to the orbicularis oris muscle...
January 12, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28078225/testicular-compartment-syndrome-an-overview-of-pathophysiology-etiology-evaluation-and-management
#5
REVIEW
Jason Gandhi, Gautam Dagur, Yefim R Sheynkin, Noel L Smith, Sardar Ali Khan
Testicular compartment syndrome (TCS) refers to the impairment of microcirculation in the testicle due to either increased venous resistance or extraluminal compression, which leads to hypoxia. TCS releases oxidants through hypoxia and ischemia/reperfusion injury (IRI). The pathophysiology, etiology, evaluation, and management of TCS are reviewed. Based on the properties of TCS, specific causes, e.g., varicocele, hydrocele, orchitis, cryptorchidism, and scrotal hernia, are suggested and categorized. The oxidant-induced stress from TCS may explain the correlations between these causes and infertility...
December 2016: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28062044/multiplexed-tethered-particle-microscopy-for-studies-of-dna-enzyme-dynamics
#6
S Ucuncuoglu, D A Schneider, E R Weeks, D Dunlap, L Finzi
DNA is the carrier of genetic information and, as such, is at the center of most essential cellular processes. To regulate its physiological function, specific proteins and motor enzymes constantly change conformational states with well-controlled dynamics. Twenty-five years ago, Schafer, Gelles, Sheetz, and Landick employed the tethered particle motion (TPM) technique for the first time to study transcription by RNA polymerase at the single-molecule level. TPM has since then remained one of the simplest, most affordable, and yet incisive single-molecule techniques available...
2017: Methods in Enzymology
https://www.readbyqxmd.com/read/28058953/use-of-a-subdermal-plexus-flap-to-reconstruct-an-upper-eyelid-following-radical-tumor-resection-in-a-cat
#7
Filipe C Dias, Alan Danielski, Kate Forster, David L Williams
CASE DESCRIPTION A 15-year-old neutered male domestic shorthair cat was examined for treatment of a recurrent neoplastic mass in the left upper eyelid that had been excised 6 months earlier by the referring veterinarian. CLINICAL FINDINGS An apparently nonpainful firm cutaneous mass (approx 2 × 2 mm) was located on the lateral third of the left upper eyelid near the scar from the previous surgical excision. TREATMENT AND OUTCOME Approximately one-third of the left upper lip was used as a subdermal plexus (lip-to-lid) flap to cover the defect created by en bloc excision of the eyelid mass...
January 15, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28052836/functional-recovery-following-an-l-lengthening-local-tendon-flap-for-extensor-pollicis-longus-chronic-ruptures
#8
Luis Lobo-Escolar, Isabel López Moreno, Marta Pérez Montoya, Manel Bosch-Aguilá
PURPOSE: Extensor indicis proprius tendon transfer has been considered the reference standard technique for extensor pollicis longus (EPL) chronic ruptures, but relevant complications have been reported. We describe a new reconstructive technique for chronic EPL ruptures and assess functional recovery after this procedure. METHODS: We observed 31 patients who fulfilled inclusion criteria an average of 6.8 months after treatment. An L-shaped local tendon flap was prepared by making a transverse incision to the middle of the tendon and then longitudinally toward the end of one of the tendon stumps...
January 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28048550/su-f-t-481-physics-evaluation-of-a-newly-released-incise%C3%A2-multileaf-collimator-for-cyberknife-m6%C3%A2-system
#9
L Wang, E Chin, A Lo
PURPOSE: This work reports the results of the physics evaluation of a newly released InCise™2 Multileaf Collimator (MLC) installed in our institution. METHODS: Beam property data was measured with unshielded diode and EBT2 films. The measurements included MLC leaf transmission, beam profiles, output factors and tissue-phantom ratios. MLC performance was evaluated for one month after commissioning. Weekly Garden Fence tests were performed for leaf / bank positioning in standard (A/P) and clinically relevant non-standard positions, before and after MLC driving exercises of 10+ minutes...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046159/technical-note-a-new-surgical-technique-for-ovariohysterectomy-during-early-pregnancy-in-beef-heifers
#10
K J McLean, C R Dahlen, P P Borowicz, L P Reynolds, M R Crosswhite, B W Neville, S D Walden, J S Caton
We hypothesized that a standing flank ovariohysterectomy procedure could be developed in beef heifers that would provide high quality tissues for addressing critical questions during early pregnancy, while concomitantly keeping livestock stewardship a high priority. To test the hypothesis, we: 1) developed a standing flank ovariohysterectomy procedure for use in beef heifers, and 2) implemented this procedure in a cohort of heifers up to d 50 of pregnancy for tissue collections, documentation of post-surgical recovery, and assessment of feedlot finishing performance...
December 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/28039506/microsurgical-anatomy-of-branches-of-musculocutaneous-nerve-clinical-relevance-for-spastic-elbow-surgery
#11
C Thieffry, L Chenin, P Foulon, E Havet, J Peltier
PURPOSE: The neurotomy of musculocutaneous nerve is a treatment for patients who suffer from spastic elbow flexion when medical and reeducative treatments have failed. It consists in sectioning motor branches of musculocutaneous nerve which are destined to the biceps brachii and brachialis muscles, both being the main elbow flexor muscles. The aim of this study was to analyse the distance, where each motor branch arises from the musculocutaneous nerve to both biceps brachii and brachialis muscles, to establish precisely the localisation and length of the necessary incision to reach its branches for surgery...
December 30, 2016: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28034574/orthodontic-camouflage-versus-orthognathic-surgery-for-class-iii-deformity-comparative-cephalometric-analysis
#12
P Martinez, C Bellot-Arcís, J M Llamas, R Cibrian, J L Gandia, V Paredes-Gallardo
The objective of this study was to compare different cephalometric variables in adult patients with class III malocclusions before and after treatment, in order to determine which variables are indicative of orthodontic camouflage or orthognathic surgery. The cases of 156 adult patients were assessed: 77 treated with orthodontic camouflage and 79 treated with orthodontics and orthognathic surgery. The following cephalometric variables were measured on pre-treatment (T1) and post-treatment (T2) lateral cephalograms: sella-nasion-A-point (SNA), sella-nasion-B-point (SNB), and A-point-nasion-B-point (ANB) angles, Wits appraisal, facial axis angle, mandibular plane angle, upper and lower incisor inclination, and inter-incisal angle...
December 26, 2016: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28029490/factors-influencing-drainage-setting-and-cost-for-cutaneous-abscesses-among-pediatric-patients
#13
Corrie E Chumpitazi, Chris A Rees, Elizabeth A Camp, Karina L Valdez, Benjamin Choi, Bruno P Chumpitazi, Faria Pereira
OBJECTIVE: To evaluate the clinical and microbiological factors associated with skin and soft tissue infections drained in the emergency department (ED) vs operative drainage (OD) in a tertiary care children's hospital. METHODS: This was a cross-sectional study among children aged 2 months to 17 years who required incision and drainage (I&D). Demographic information, signs and symptoms, abscess size and location, and wound culture/susceptibility were recorded. Patient-specific charges were collected from the billing database...
October 17, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28028627/effect-of-electroacupuncture-on-the-cervicospinal-p2x7-receptor-fractalkine-cx3cr1-signaling-pathway-in-a-rat-neck-incision-pain-model
#14
Y H Gao, C W Li, J Y Wang, L H Tan, C L Duanmu, X H Jing, X R Chang, J L Liu
Increasing evidence supports that acupuncture intervention is an effective approach for intraoperative and postoperative pain. Neuron-microglia crosstalk, mediated by the purinergic P2X7 receptor (R)/fractalkine/CX3CR1 cascade in the spinal cord dorsal horn, plays a pivotal role in pain processing. However, its involvement in the analgesic effect of electroacupuncture (EA) remains unclear. In this study, a rat neck-incision pain model was established by making a longitudinal incision along the midline of the neck and subsequent repeated mechanical stimulation...
December 27, 2016: Purinergic Signalling
https://www.readbyqxmd.com/read/28027258/evidence-based-medicine-options-for-dupuytren-s-contracture-incise-excise-and-dissolve
#15
Keith A Denkler, Carolyn J Vaughn, Estelle L Dolan, Scott L Hansen
LEARNING OBJECTIVES: After studying this article, the participant should be able to: 1. Understand updates in the basic science, epidemiology, and treatment of Dupuytren's disease. 2. Understand treatment with needle aponeurotomy, collagenase, and fasciectomy. 3. Understand advanced needle techniques for Dupuytren's contracture. 4. Understand the safety and effectiveness of a new treatment, collagenase. SUMMARY: The literature on Dupuytren's disease encompasses many specialties...
January 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28013322/a-giant-pancreatic-pseudocyst-treated-by-open-cystogastrostomy
#16
Artur Pasternak, Przemysław Wawok, Piotr Richter
We report a case of a giant pancreatic pseudocyst in a 33-year-old woman presenting with abdominal pain, loss of appetite and abdominal distension. CT scans revealed a giant pancreatic pseudocyst measuring 10.3 cm × 9.6 cm × 9.3 cm anteroposteriorly, with significant compression of the stomach. An open retrogastric cystogastrostomy was performed through a midline incision, and 3 L of fluid was drained from the pseudocyst. Recovery has been uneventful.
2016: Folia Medica Cracoviensia
https://www.readbyqxmd.com/read/28012031/first-200-consecutive-transumbilical-single-incision-laparoscopic-teps
#17
G Dapri, L Gerard, M Paesmans, G-B Cadière, S Saussez
BACKGROUND: Endoscopic pre-peritoneal mesh repair (TEP) through single-incision laparoscopy (SIL) permits placement of a large mesh through a final millimetric umbilical scar. This prospective study evaluates the first 200 consecutive SILTEPs performed by a single surgeon. PATIENTS AND METHODS: Between November 2011 and September 2015, 200 consecutive SILTEPs were performed in 161 patients. The mean age was 49.8 ± 16.3 years and the mean BMI was 24.5 ± 3...
December 23, 2016: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/28009729/impact-of-enhanced-recovery-after-surgery-and-fast-track-surgery-pathways-on-healthcare-associated-infections-results-from-a-systematic-review-and-meta-analysis
#18
Michael C Grant, Dongjie Yang, Christopher L Wu, Martin A Makary, Elizabeth C Wick
OBJECTIVE: The aim of this study was to establish if enhanced recovery after surgery (ERAS) and fast track surgery (FTS) protocols are associated with reduction in healthcare-associated infection (HAIs). BACKGROUND: Evidence suggests that prevention strategies for HAIs should be multifaceted and transdisciplinary. ERAS and FTS protocols are collaborative approaches to perioperative care which reduce length of stay but may also be an effective strategy for reducing HAIs...
January 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28005143/acidic-cellular-microenvironment-modifies-carcinogen-induced-dna-damage-and-repair
#19
Q Shi, L Maas, C Veith, F J Van Schooten, R W Godschalk
Chronic inflammation creates an acidic microenvironment, which plays an important role in cancer development. To investigate how low pH changes the cellular response to the carcinogen benzo[a]pyrene (B[a]P), we incubated human pulmonary epithelial cells (A549 and BEAS-2B) with nontoxic doses of B[a]P using culturing media of various pH's (extracellular pH (pHe) of 7.8, 7.0, 6.5, 6.0 and 5.5) for 6, 24 and 48 h. In most incubations (pHe 7.0-6.5), the pH in the medium returned to the physiological pH 7.8 after 48 h, but at the lowest pH (pHe < 6...
December 22, 2016: Archives of Toxicology
https://www.readbyqxmd.com/read/27999040/population-pharmacokinetics-of-cefazolin-before-during-and-after-cardiopulmonary-bypass-to-optimize-dosing-regimens-for-children-undergoing-cardiac-surgery
#20
Pieter A J G De Cock, Hussain Mulla, Sarah Desmet, Filip De Somer, Brett C McWhinney, Jacobus P J Ungerer, Annelies Moerman, Sabrina Commeyne, Johan Vande Walle, Katrien Francois, Johan G C Van Hasselt, Peter De Paepe
OBJECTIVES: The objective of this study was to characterize cefazolin serum pharmacokinetics in children before, during and after cardiopulmonary bypass (CPB), in order to derive an evidence-based dosing regimen. PATIENTS AND METHODS: This study included children who received cefazolin before surgical incision, before cessation of CPB and after surgery. Blood samples of total and unbound cefazolin concentrations were collected before, during and after CPB. The cefazolin concentration-time profiles were analysed using population pharmacokinetic modelling and predictors for interindividual variability in pharmacokinetic parameters were investigated...
December 20, 2016: Journal of Antimicrobial Chemotherapy
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