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Pratiksha Chheda, Sandeep Warghade, Jyothi Mathias, Tavisha Dama, Sunmeet Matkar, Nilesh Shah, Rajesh Bendre
BACKGROUND: Determination of HLA-B27 status plays an important role as adjuvant in suspected cases for diagnosis of Ankylosing Spondilytis (AS). Objectives of this study were to evaluate (i) flow cytometry method in comparison with DNA microarray for HLA-B27 typing and (ii) EUROArray HLA-B27 Direct assay for HLA-B27 allele detection along with discrimination of AS/non-AS subtypes in Indian population. METHODS: A total of 7543 patients with a presumptive clinical diagnosis of AS were referred for screening of HLA-B27...
January 19, 2018: Journal of Clinical Laboratory Analysis
Alexandra Maria Giovanna Brunasso, Werner Aberer, Cesare Massone
We performed a systematic search of databases from 1990 to 2013 to identify articles concerning the new onset of dermatomyositis/polymyositis (DM/PM) in patients treated with anti-TNF-α therapy. We retrieved 13 publications describing 20 patients where the new onset of DM/PM after anti-TNF-α therapy was recorded. 17 patients were affected by rheumatoid arthritis (RA), one by Crohn's disease, one by ankylosing spondilytis, and one by seronegative arthritis. In 91% of the cases antinuclear autoantibodies were detected after the introduction of anti-TNF-α therapy...
2014: TheScientificWorldJournal
Mediha Ortaköylü, Ayse Bahadir, Derya Soy, Emel Caglar, Nurdan Paker, Figen Alkan, Kaya Koksalan, Ekrem Seyhan
SESSION TYPE: Respiratory Infections Posters IPRESENTED ON: Wednesday, October 24, 2012 at 01:30 PM - 02:30 PMPURPOSE: Screening for active tuberculosis (TB) and latent TB infection (LTBI) is mandatory prior to the initiation of tumour necrosis factor-α inhibitor therapy. However, no agreement exists on the best strategy for detecting LTBI in this population. We tested the diagnostic performance of tuberculin skin tes (TST) interferon-gamma (IFN-γ) inducible protein 10 (IP-10) and IFN-γ for detecting LTBI in rheumatic diseases patients...
October 1, 2012: Chest
Lucio Ventura-Ríos, David Bañuelos-Ramírez, María del Carmen Hernández-Quiroz, Manuel Robles-San Román, Fedra Irazoque-Palazuelos, María Victoria Goycochea-Robles
This work reports patient treatment survival and adverse events related to Biologic Therapy (BT), identified by a multicenter ambispective registry of 2047 rheumatic patients undergoing BT and including a control group of Rheumatoid Arthritis (RA) patients not using BT. The most common diagnoses were: RA 79.09%, Ankylosing Spondilytis 7.96%, Psoriatic Arthritis 4.40%, Systemic Lupus Erythematosus 3.37%, Juvenile Idiopathic Arthritis 1.17%. A secondary analysis included 1514 cases from the total sample and was performed calculating an incidence rate of any adverse events of 178 × 1000/BT patients per year vs 1009 × 1000/control group patients per year with a 1...
July 2012: Reumatología Clinica
Mioara-Maria Tigău, Alina Manole, M Manole, Mihaela Trifan
UNLABELLED: During the period of study, the prevalence of ankylosing spondylitis (AS) cases values varied between 5.65% per hundred thousand in 1994 and 3.96 in 1999. RESULTS: Are close to those obtained in the national research in 1989 (5.29% hundred thousand) and 1997 (6.34% hundred thousand). The sample of 6894 cases registered a prevalence of 28.86% in the 35-44 age groups with a decreasing trend, and 0.07% in = 85 age group. Males' prevalence was of 84.08%, comparatively with females (15...
April 2008: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
S Constantiniu, A Romaniuc, R Chiriac, C Berea, O Kalis, E Rezus, M Mutica
The presence of the specific antibodies for some enterobacteria--Yersinia, Salmonella and Shigella was investigated in patients hospitalized in the period 2000-2007 with reactive arthritis and other rheumatoid diseases. The antibacterial antibodies in the diagnosis titres were found in 172 out of 1102 (15.6%) patients. Increased antibodies levels to Yersinia were detected in the sera from 113 (65.7%) of the 172 patients, for Shigella in 47 (27.3%) and for Salmonella in 12 (7.0%) cases. From all serologically positive patients 126 (73...
January 2008: Roumanian Archives of Microbiology and Immunology
Frane Grubisić, Simeon Grazio, Matea Znika
Ankylosing spondylitis is a chronic inflammatory rheumatic disease that primarily affects the sacroiliac joints and spine, although it may involve entheses, peripheral joints and extraarticular organs. Disease treatment is directed toward the suppression of the inflammatory process and the improvement of the musculoskeletal system function. There are several treatment modalities: education of the patient and members of the family, pharmacological treatment, physical therapy and, in some cases, surgical treatment...
2007: Acta Medica Croatica: C̆asopis Hravatske Akademije Medicinskih Znanosti
E Balliu, J C Vilanova, I Peláez, J Puig, S Remollo, C Barceló, J Barceló, S Pedraza
AIM: The aim of this study is to evaluate the value of the apparent diffusion coefficient (ADC) obtained in diffusion-weighted (DW) MR sequences for the differentiation between malignant and benign bone marrow lesions. METHOD: Forty-five patients with altered signal intensity vertebral bodies on conventional MR sequences were included. The cause of altered signal intensity was benign osteoporotic collapse in 16, acute neoplastic infiltration in 15, and infectious processes in 14; based on plain-film, CT, bone scintigraphy, conventional MR studies, biopsy or follow-up...
March 2009: European Journal of Radiology
M C Sharma, R Arora, A K Mahapatra, P Sarat-Chandra, S B Gaikwad, C Sarkar
OBJECTIVE: Intrasellar tuberculomas are rare and only few case reports have been described in the literature. We report a series of 18 cases of histologically proven intrasellar tuberculomas, which, to the best of our knowledge, is the largest series in the English literature. METHODS: A total of 1143 pituitary lesions, between 1984 and June 1999, were operated for various reasons in our institute. Of these, 18 cases were histopathologically proven intrasellar tuberculomas...
June 2000: Clinical Neurology and Neurosurgery
J Correia, P Barbosa, P Paiva, A Ferreira, C Vasconcelos, B Leão, M Marques, P Torres, H Branco, B M Da Silva
Uveitis is a general term that refers to the inflammation of uveal tract, which is an important cause of blindness in young people. It is well known that uveitis can be the initial manifestation of a systemic disease (S.D.), and may appear years before the diagnosis of the primary disease. Uveitis should be integrated in a systemic study with proper testing. Therefore, the diagnosis is a matter for the ophthalmologist and the Specialist in internal medicine. We have made a retrospective study of 71 patients with chronic uveitis or panuveitis...
October 1998: Acta Médica Portuguesa
Z Jajić, I Jajić, M Dubravica, M Sisek, B Serbo
The characteristics of the pain were investigated in 99 ankylosing spondylitis patients (62 men and 37 women) from 17 to 70 years with various developing stadies of sacroileitis. The analysis of the sacroileitis pain characteristics revealed the dominance of appearing in rest (at night and by day rest) and obligatory morning low back stiffness. The intensity of pain was more severe in women, more dull, located inguinally, in low abdomen and symphysis. The pain propagated on more distant locations (the tight and the leg), shortly or for longer period in one and/or both legs...
1994: Reumatizam
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