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https://www.readbyqxmd.com/read/28938394/risk-factors-for-failure-of-bone-grafting-of-tibia-nonunions-and-segmental-bone-defects-a-new-preoperative-risk-assessment-score
#1
Michael A Maceroli, Mark J Gage, Brent T Wise, Daniel Connelly, Katherine Ordonio, Renan C Castillo, Molly P Jarman, Jason W Nascone, Robert V OʼToole, Marcus F Sciadini
OBJECTIVE: To develop a clinically useful prediction model of success at the time of surgery to promote bone healing for established tibial nonunion or traumatic bone defects. DESIGN: Retrospective case controlled. SETTING: Level 1 trauma center. PATIENTS: Adult patients treated with surgery for established tibia fracture nonunion or traumatic bone defects from 2007 to 2016. Two hundred three patients met the inclusion criteria and were available for final analysis...
October 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28930951/routine-computed-tomography-after-recent-operative-exploration-for-penetrating-trauma-what-injuries-do-we-miss
#2
April E Mendoza, Christopher A Wybourn, Anthony G Charles, Andre R Campbell, Bruce A Cairns, Margaret M Knudson
BACKGROUND: Patients with penetrating trauma who cannot be stabilized undergo operative intervention without preoperative imaging. In such cases, postoperative imaging may reveal additional injuries not identified during the initial operative exploration. The purpose of this study is to explore the utility of postoperative CT imaging in the setting of penetrating trauma. METHODS: This was a retrospective analysis of patients with penetrating trauma treated at an urban Level 1 trauma center between 2010 and 2015...
October 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28923767/shrinkage-of-spray-freeze-dried-microparticles-of-pure-protein-for-ballistic-injection-by-manipulation-of-freeze-drying-cycle
#3
Georg Straller, Geoffrey Lee
Spray-freeze-drying was used to produce shrivelled, partially-collapsed microparticles of pure proteins that may be suitable for use in a ballistic injector. Various modifications of the freeze drying cycle were examined for their effects on collapse of the pure protein microparticles. The use of annealing at a shelf temperature of up to +10°C resulted in no visible particle shrinkage. This was because of the high Tg' of the pure protein. Inclusion of trehalose or sucrose led to particle shrinkage because of the plasticizing effects of the disaccharides on the protein...
September 15, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28914343/image-guided-percutaneous-removal-of-ballistic-foreign-bodies-secondary-to-air-gun-injuries
#4
Jacob L Rothermund, Andrew J Rabe, Nicholas A Zumberge, James W Murakami, Patrick S Warren, Mark J Hogan
BACKGROUND: Ballistic injuries with retained foreign bodies from air guns is a relatively common problem, particularly in children and adolescents. If not removed in a timely fashion, the foreign bodies can result in complications, including pain and infection. Diagnostic methods to identify the presence of the foreign body run the entire gamut of radiology, particularly radiography, ultrasound (US) and computed tomography (CT). Removal of the foreign bodies can be performed by primary care, emergency, surgical, and radiologic clinicians, with or without imaging guidance...
September 15, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28910472/a-descriptive-analysis-of-occupational-fatalities-due-to-felonious-assault-among-u-s-law-enforcement-officers-during-tactical-incidents-1996-2014
#5
Moriah S Thompson, Tyler M Hartman, Matthew D Sztajnkrycer
INTRODUCTION: Little is known about occupational fatalities among tactical officers. A greater understanding of such injuries is needed to improve officer safety. The purpose of this study was to provide a descriptive analysis of line-of-duty deaths secondary to felonious assault during tactical incidents. METHODS: Retrospective analysis was performed of open-source de-identified Federal Bureau of Investigation Uniform Crime Reporting Law Enforcement Officers Killed and Assaulted (LEOKA) data inclusive of the years 1996-2014...
2017: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
https://www.readbyqxmd.com/read/28898046/linking-catalyst-coated-isotropic-colloids-into-active-flexible-chains-enhances-their-diffusivity
#6
Bipul Biswas, Raj Kumar Manna, Abhrajit Laskar, P B Sunil Kumar, Ronojoy Adhikari, Guruswamy Kumaraswamy
Active colloids are not constrained by equilibrium: ballistic propulsion, superdiffusive behavior, or enhanced diffusivities have been reported for active Janus particles. At high concentrations, interactions between active colloids give rise to complex emergent behavior. Their collective dynamics result in the formation of several hundred particle-strong flocks or swarms. Here, we demonstrate significant diffusivity enhancement for colloidal objects that neither have a Janus architecture nor are at high concentrations...
September 22, 2017: ACS Nano
https://www.readbyqxmd.com/read/28889869/the-sharing-of-ballistics-data-across-europe-and-neighbouring-territories
#7
F Jeane Gerard, Rebecca L Crookes, Susan Elliott, Michael Hellenbach, Athanasios Stamos, Helen Poole, Erica Bowen
The current study explored the use of ballistic examinations and cross-border information sharing across 14 European countries. The presented data were collected using a mixed methods technique consisting of semi-structured interviews and questionnaires that were completed by participants. The results painted a very heterogeneous picture of the use of automated ballistic systems across these countries, as well as how ballistic analyses are integrated in the fight against gun-enabled crime. Three super-ordinates themes emerged from the thematic analysis: use of automated ballistic systems; Ballistic evidence recovery and analysis; knowledge exchange and best practices...
September 2017: Science & Justice: Journal of the Forensic Science Society
https://www.readbyqxmd.com/read/28885389/load-velocity-relationship-in-variations-of-the-half-squat-exercise-influence-of-execution-technique
#8
Alejandro Pérez-Castilla, Amador García-Ramos, Paulino Padial, Antonio J Morales-Artacho, Belén Feriche
Previous studies have revealed that the velocity of the bar can be used to determine the intensity of different resistance training exercises. However, the load-velocity relationship seems to be exercise dependent. This study aimed to compare the load-velocity relationship obtained from two variations of the half-squat exercise (traditional vs. ballistic) using two execution techniques (eccentric-concentric vs. concentric-only). Twenty men performed a submaximal progressive loading test in four half-squat exercises: eccentric-concentric traditional-squat, concentric-only traditional-squat, countermovement jump (i...
September 6, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28883492/on-the-role-of-initial-velocities-in-pair-dispersion-in-a-microfluidic-chaotic-flow
#9
Eldad Afik, Victor Steinberg
Chaotic flows drive mixing and efficient transport in fluids, as well as the associated beautiful complex patterns familiar to us from our every day life experience. Generating such flows at small scales where viscosity takes over is highly challenging from both the theoretical and engineering perspectives. This can be overcome by introducing a minuscule amount of long flexible polymers, resulting in a chaotic flow dubbed 'elastic turbulence'. At the basis of the theoretical frameworks for its study lie the assumptions of a spatially smooth and random-in-time velocity field...
September 7, 2017: Nature Communications
https://www.readbyqxmd.com/read/28883031/neuropathic-pain-treatment-and-research-experiences-from-the-united-kingdom-mission-to-afghanistan-and-future-prospects
#10
REVIEW
Paul Wood, C Small, S Lewis, P Mahoney
The Defence Medical Services (DMS) of the United Kingdom (UK) assumed command of the Role 3 Medical Treatment Facility field hospital during Operation HERRICK in Afghanistan from April 2006 until the final drawdown in November 2014. The signature injury sustained by coalition personnel during this period was traumatic amputation from improvised explosive devices. Many patients who had suffered extensive tissue damage experienced both nociceptive and neuropathic pain (NeuP). This presented as a heterogeneous collection of symptoms that are resistant to treatment...
September 6, 2017: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/28883025/do-air-gaps-behind-soft-body-armour-affect-protection
#11
Lee Tilsley, D J Carr, C Lankester, C Malbon
INTRODUCTION: Body armour typically comprises a fabric garment covering the torso combined with hard armour (ceramic/composite). Some users wear only soft armour which provides protection from sharp weapons and pistol ammunition. It is usually recommended that body armour is worn against the body with no air-gaps being present between the wearer and the armour. However, air-gaps can occur in certain situations such as females around the breasts, in badly fitting armour and where manufacturers have incorporated an air-gap claiming improvements in thermophysiological burden...
September 6, 2017: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/28879213/dna-loaded-cationic-liposomes-efficiently-function-as-a-vaccine-against-malarial-proteins
#12
Wesley L Fotoran, Rachele Santangelo, Beatriz N M de Miranda, Darrell J Irvine, Gerhard Wunderlich
The delivery of antigens as DNA vaccines is an efficient alternative to induce immune responses against antigens, which are difficult to produce in recombinant form. However, the delivery of naked DNA is ineffective or relies on sophisticated ballistic devices. Here, we show a combination of liposome application and naked DNA vaccine that successfully overcomes these problems. Upon entrapment of plasmids encoding different antigens in cationic particles, transfection efficiencies similar to commercial kits were achieved in in vitro cell cultures...
December 15, 2017: Molecular Therapy. Methods & Clinical Development
https://www.readbyqxmd.com/read/28877266/feasibility-of-using-a-hand-held-device-to-characterize-tendon-tissue-biomechanics
#13
Sahand Sohirad, David Wilson, Charlotte Waugh, Evan Finnamore, Alexander Scott
OBJECTIVES: To examine the feasibility of using the MyotonPRO digital palpation device in measuring the transverse stiffness of tendon tissue. DESIGN: Experimental study. METHODS: The MyotonPRO was used to measure the stiffness and related properties of ballistics gel in comparison with an external materials testing system (PCB electronics). The device was then used to measure the same properties of avian Achilles tendons before and after the removal of the overlying skin and subcutaneous tissue...
2017: PloS One
https://www.readbyqxmd.com/read/28875170/photoinduced-nanobubble-driven-superfast-diffusion-of-nanoparticles-imaged-by-4d-electron-microscopy
#14
Xuewen Fu, Bin Chen, Jau Tang, Ahmed H Zewail
Dynamics of active or propulsive Brownian particles in nonequilibrium status have recently attracted great interest in many fields including artificial micro/nanoscopic motors and biological entities. Understanding of their dynamics can provide insight into the statistical properties of physical and biological systems far from equilibrium. We report the translational dynamics of photon-activated gold nanoparticles (NPs) in water imaged by liquid-cell four-dimensional electron microscopy (4D-EM) with high spatiotemporal resolution...
August 2017: Science Advances
https://www.readbyqxmd.com/read/28869218/novel-boron-channel-based-structure-of-boron-carbide-at-high-pressures
#15
Xinxin Zhang, Yu Zhao, Miao Zhang, Hanyu Liu, Yansun Yao, Taimin Cheng, Hui Chen
Boron carbide (B4C) is one of the hardest materials known to date. The extreme hardness of B4C arises from architecturally efficient B12 or B11C icosahedrons and strong inter-icosahedral B-C bonding. As an excellent material for use in ballistic armor, the mechanic limit of B4C and possible phase transitions under extreme stress conditions are of great interest. Here we systematically explored the post-icosahedral solid structures of B4C under high pressure, using an unbiased structure search method. A new structure composed of extended framework of B and zigzag chains of C is predicted to be stable above 96 GPa...
September 4, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28868355/stability-of-gene-expression-in-human-t-cells-in-different-gravity-environments-is-clustered-in-chromosomal-region-11p15-4
#16
Cora S Thiel, Andreas Huge, Swantje Hauschild, Svantje Tauber, Beatrice A Lauber, Jennifer Polzer, Katrin Paulsen, Hartwin Lier, Frank Engelmann, Burkhard Schmitz, Andreas Schütte, Liliana E Layer, Oliver Ullrich
In the last decades, a plethora of in vitro studies with living human cells contributed a vast amount of knowledge about cellular and molecular effects of microgravity. Previous studies focused mostly on the identification of gravity-responsive genes, whereas a multi-platform analysis at an integrative level, which specifically evaluates the extent and robustness of transcriptional response to an altered gravity environment was not performed so far. Therefore, we investigated the stability of gene expression response in non-activated human Jurkat T lymphocytic cells in different gravity environments through the combination of parabolic flights with a suborbital ballistic rocket and 2D clinostat and centrifuge experiments, using strict controls for excluding all possible other factors of influence...
2017: NPJ Microgravity
https://www.readbyqxmd.com/read/28863126/a-histological-analysis-of-visceral-organs-to-evaluate-the-effect-of-duration-of-heating-from-refrigeration-to-core-body-temperature-for-ballistics-investigations
#17
Caitlin Humphrey, Jaliya Kumaratilake
Animal organs have been used in ballistics research to investigate the effects on human organs. Such organs are refrigerated until the investigation to minimize autolytic degradation and at times have been reheated to the human core body temperature to simulate the in situ environment. The aim of this investigation was to study the microstructural changes that may occur in fresh chilled visceral organs of the thorax and abdomen (ie, heart, lung, liver, and kidney) during the period of reheating to 37°C. Fifty-millimeter cubes of porcine heart, lung, liver, and kidney were taken rapidly after slaughter, chilled overnight, and the next morning were reheated to core body temperature (37°C)...
August 31, 2017: American Journal of Forensic Medicine and Pathology
https://www.readbyqxmd.com/read/28860078/removing-eye-blink-artefacts-from-eeg-a-single-channel-physiology-based-method
#18
Shenghuan Zhang, Julia McIntosh, Shabah M Shadli, Phoebe S-H Neo, Zhiyi Huang, Neil McNaughton
BACKGROUND: EEG signals are often contaminated with artefacts, particularly with large signals generated by eye blinks. Deletion of artefact can lose valuable data. Current methods of removing the eye blink component to leave residual EEG, such as blind source component removal, require multichannel recording, are computationally intensive, and can alter the original EEG signal. NEW METHOD: Here we describe a novel single-channel method using a model based on the ballistic physiological components of the eye blink...
August 30, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28859833/massively-parallel-simulator-of-optical-coherence-tomography-of-inhomogeneous-turbid-media
#19
Siavash Malektaji, Ivan T Lima, Mauricio R Escobar I, Sherif S Sherif
BACKGROUND AND OBJECTIVE: An accurate and practical simulator for Optical Coherence Tomography (OCT) could be an important tool to study the underlying physical phenomena in OCT such as multiple light scattering. Recently, many researchers have investigated simulation of OCT of turbid media, e.g., tissue, using Monte Carlo methods. The main drawback of these earlier simulators is the long computational time required to produce accurate results. We developed a massively parallel simulator of OCT of inhomogeneous turbid media that obtains both Class I diffusive reflectivity, due to ballistic and quasi-ballistic scattered photons, and Class II diffusive reflectivity due to multiply scattered photons...
October 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28852038/artificial-gravity-effect-on-spin-polarized-exciton-polaritons
#20
E S Sedov, A V Kavokin
The pseudospin dynamics of long-living exciton-polaritons in a wedged 2D cavity has been studied theoretically accounting for the external magnetic field effect. The cavity width variation plays the role of the artificial gravitational force acting on a massive particle: exciton-polariton. A semi-classical model of the spin-polarization dynamics of ballistically propagating exciton-polaritons has been developed. It has been shown that for the specific choice of the magnetic field magnitude and the initial polariton wave vector the polariton polarization vector tends to an attractor on the Poincaré sphere...
August 29, 2017: Scientific Reports
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