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Esophagic atresia

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https://www.readbyqxmd.com/read/29931283/location-of-tef-at-the-carina-as-an-indicator-of-long-gap-c-type-esophageal-atresia
#1
A Koivusalo, J Suominen, R Rintala, M Pakarinen
We analyzed retrospectively the outcomes in long gap Gross type C esophageal atresia. We hypothesized that outcomes in type C (long gap) atresia differ from type C (normal gap) and be similar with outcomes in Gross type A and B esophageal atresia. Location of the distal tracheoesophageal fistula (TEF) at the carina was chosen as the hallmark of type C atresia (long gap). We compared the type of esophageal repair, major reoperations for anastomotic complications and gastroesophageal reflux, and long-term mucosal changes between type C (normal gap), type C (long gap), and type A/B...
June 19, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
https://www.readbyqxmd.com/read/29927863/endoscopic-esophageal-vacuum-therapy-a-novel-therapy-for-esophageal-perforations-in-pediatric-patients
#2
Michael A Manfredi, Susannah J Clark, Steven J Staffa, Peter D Ngo, C Jason Smithers, Thomas E Hamilton, Russell W Jennings
BACKGROUND: Esophageal perforation is a potentially life-threatening problem if not quickly diagnosed and treated appropriately. Negative pressure wound therapy (NPWT), commercially known as V.A.C.® therapy, was developed in the early 1990 s and is now standard of care for chronic surface wounds, ulcers, and burns. Adapting vacuum sponge therapy for use intraluminally for perforations of the esophagus was first reported in 2008. We report the first pediatric experience on a customized esophageal vacuum assisted closure (EVAC) device for closure of esophageal perforations...
June 20, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29920636/quality-of-life-in-parents-of-children-born-with-esophageal-atresia
#3
Stefanie Witt, Michaela Dellenmark-Blom, Jens Dingemann, Carmen Dingemann, Benno M Ure, Barbara Gomez, Monika Bullinger, Julia Quitmann
INTRODUCTION:  For parents of chronically ill children, the experiences of caregiving are challenged by increased demands and restrictions imposed by their child's disease. Therefore, this study aims to investigate the quality of life (QoL) in parents of children born with esophageal atresia (EA) and to explore associated factors. METHODS:  Parents of children (2-17 years) with EA recruited from two German pediatric hospitals participated in this cross-sectional study about QoL in EA...
June 19, 2018: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29914284/congenital-heart-defects-the-10-year-experience-at-a-single-center
#4
Emine Aydin, Ebru Aypar, Ahmet Oktem, Ozgur Ozyuncu, Murat Yurdakok, Murat Guvener, Metin Demircin, M Sinan Beksac
OBJECTIVE: We aimed to evaluate congenital heart disease (CHD) cases according to EUROCAT subgroup classification that were diagnosed during the prenatal period in our center. METHODS: CHDs that were prenatally diagnosed using ultrasonography and confirmed by fetal echocardiography were reviewed over a 10-year period. Subgroup classification was finalized at the post-partum period in terms of the EUROCAT guide 1.3. Congenital heart defect subtypes and obstetric outcomes (gestational week at delivery, birth weight, gender, extracardiac structural abnormalities, karyotype results if performed) were analyzed...
June 18, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29905609/double-supercharged-jejunal-interposition-for-late-salvage-of-long-gap-esophageal-atresia
#5
Ingrid M Ganske, Joseph M Firriolo, Laura C Nuzzi, Oren Ganor, Thomas E Hamilton, C Jason Smithers, Russell W Jennings, Joseph Upton, Brian I Labow, Amir H Taghinia
BACKGROUND: A variety of surgical techniques exist to manage long-gap esophageal atresia (LGEA), including gastric pull-up (GPU), colonic interposition (CI), jejunal interposition (JI), and distraction lengthening. Salvage reconstruction for late failure of any conduit type is a complex surgical problem fraught with technical difficulty and significant risk. Jejunal interposition can be used as a salvage procedure in the management of LGEA. However, the opposing requirements of conduit length and adequate perfusion make the procedure technically challenging...
June 13, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29904493/esophageal-lung-with-rare-associated-vascular-and-anorectal-malformations
#6
Ali Alsaadi, Hamdi A Alsufiani, Mohammad D Allugmani, Altaf Hussain Gora
Esophageal lung is a rare communicating bronchopulmonary foregut malformation in which the main bronchus arising from the trachea is absent. The affected lung is usually hypoplastic and aerated via an anomalous airway originating from the esophagus. Other anomalies such as esophageal atresia with tracheoesophageal fistula or VACTERL (vertebral defects, anal atresia, cardiac defects, tracheoesophageal fistula, renal anomalies, and limb abnormalities) association can co-exist. The initial radiographic findings may be normal, but subsequent imaging usually shows progressive and recurrent lung collapse, probably because of recurrent aspiration through the anomalous airway and poor compliance of the affected lung during breathing...
April 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/29901549/a-bibliometric-analysis-of-clinical-and-translational-research-in-pediatric-gastroenterology-from-1970-to-2017
#7
Melanie H Schwimmer, Mary Catherine Sawh, Karen M Heskett, Nidhi P Goyal, Kimberly P Newton, Jeffrey B Schwimmer
OBJECTIVES: Pediatric gastroenterology is a clinical and research discipline principally developed over the past 50 years. Bibliometric methods provide quantitative analysis and identify research trends. Study aims were to characterize the growth and trends in pediatric gastroenterology clinical and translational research using citation analysis. METHODS: Using citations analysis software, a search strategy specific for pediatric gastroenterology was implemented for the years 1970-2017...
June 12, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29898778/liver-transplant-score-for-prediction-of-biliary-atresia-patients-survival-following-kasai-procedure
#8
Gunadi, Timotheus Allen Gunawan, Galih Widiyanto, Amalia Yuanita, Nenny Sri Mulyani, Akhmad Makhmudi
OBJECTIVES: Recently, a scoring system has been developed to predict which patients with biliary atresia (BA) who underwent a Kasai procedure should be considered for liver transplant. Here, we applied the scoring system to predict the survival of BA patients following the Kasai procedure at Dr. Sardjito Hospital, Yogyakarta, Indonesia from January 2012 to January 2016. RESULTS: There were 26 patients, of whom 14 were males and 12 females. Outcomes of BA patients after the Kasai surgery were 15 survived and 11 died...
June 13, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29887883/congenital-heart-disease-and-its-impact-on-the-development-of-anastomotic-strictures-after-reconstruction-of-esophageal-atresia
#9
Pernilla Stenström, Martin Salö, Magnus Anderberg, Einar Arnbjörnsson
Background: The aim was to explore if severe congenital heart disease (CHD) influenced the need for dilatation of anastomotic strictures (AS) after the repair of esophageal atresia (EA). Methods: A retrospective case-control study was conducted examining AS in children with EA and Gross type C. The spectra of CHD and cardiac interventions were reviewed. The frequency of dilatations of AS during the first year following EA reconstruction was compared between children with and without severe CHD requiring cardiac surgery during their first year of life...
2018: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/29844939/clinical-applications-of-spleen-ultrasound-elastography-a-review
#10
REVIEW
Rafał Mazur, Milena Celmer, Jurand Silicki, Daniel Hołownia, Patryk Pozowski, Krzysztof Międzybrodzki
In the last few years, notable technical progress has taken place in ultrasound elastography. Qualitative methods have been replaced by quantitative ones, such as: transient elastography, acoustic radiation force impulse and shear wave elastography. Owing to the fact that the spleen is superficially located, it is possible to obtain reliable measuring accuracy of its hardness using sonoelastography. Lately, many researchers have been investigating how spleen elasticity changes in patients infected with hepatitis B virus or hepatitis C virus and in patients suffering from liver fibrosis, portal hypertension, esophageal varices or myelofibrosis...
March 2018: Journal of Ultrasonography
https://www.readbyqxmd.com/read/29804792/thoracoscopic-posterior-tracheopexy-during-primary-esophageal-atresia-repair-a-new-approach-to-prevent-tracheomalacia-complications
#11
Stefaan H A J Tytgat, Maud Y A van Herwaarden-Lindeboom, E Sofie van Tuyll van Serooskerken, David C van der Zee
BACKGROUND: Esophageal atresia (EA) is usually accompanied by some form of tracheomalacia (TM). During the early phases in life, excessive dynamic collapse of the trachea can cause a wide spectrum of symptoms ranging from mild complaints to apparent life-threatening events (ALTE's) or brief resolved unexplained events (BRUE's). Therapeutic strategies for severe TM include aortopexy to lift the anterior weakened cartilaginous rings or posterior tracheopexy of the floppy membranous tracheal intrusion...
April 27, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29796381/magnetic-compression-anastomosis-in-long-gap-esophageal-atresia-gross-type-a-a-case-report
#12
Mark Bremholm Bremholm Ellebaek, Niels Qvist, Lars Rasmussen
Esophageal atresia (EA) Gross type A (long-gap without tracheoesophageal fistula) is a rare and a surgical challenging form of EA that constitutes ∼6% of the children born with EA. We present the seventh reported case with successful esophagoesophagostomy obtained by magnetic compression of a long-gap EA type A without thoracotomy.
January 2018: European Journal of Pediatric Surgery Reports
https://www.readbyqxmd.com/read/29750630/esophageal-atresia-with-tracheoesophageal-fistula-and-gastroesophageal-reflux-in-children-dental-considerations-and-case-report
#13
J Arturo Garrocho-Rangel, Juana M Arvizu-Rivera, Nadia P Campos-Lara, Miguel A Rosales-Berber, Amaury Pozos-Guillén
BACKGROUND: Esophageal Atresia (EA) is defined as the congenital interruption of the continuity of the esophagus. Pediatric patients also have other congenital conditions, such as Tracheo-Esophageal Fistula (TEF). CASE REPORT: A 7-year-old male with TEF referred by a Pediatric Cardiologist, with the principal complaint of "severe and generalized tooth wearing". Considering that the patient was systemically stable, it was decided to perform the oral procedures under local anesthesia and rubber-dam isolation with an antimicrobial prophylaxis regimen...
May 11, 2018: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29740616/anastomotic-strictures-after-esophageal-atresia-repair-timing-of-dilatation-during-the-first-two-postoperative-years
#14
Martin Salö, Pernilla Stenström, Magnus Anderberg, Einar Arnbjörnsson
Background  We determined time frames for dilatation of anastomotic strictures (ASs) occurring during the first 2 years after esophageal atresia (EA) repair. Methods  A retrospective study was conducted on children with EA (Gross type C) who underwent direct repair between January 2008 and March 2015 at a single tertiary center of pediatric surgery. Endoscopic signs of stricture were indications for dilatation because the endoscopy provides more reliable information than X-ray imagining methods. Results  Among our cohort of 49 children with EA, 19 (39%) required at least one esophageal dilatation...
April 2018: Surgery Journal
https://www.readbyqxmd.com/read/29739032/management-and-outcome-of-neonates-with-a-prenatal-diagnosis-of-esophageal-atresia-type-a-a-population-based-study
#15
C Garabedian, A Bonnard, V Rousseau, R Sfeir, S Blanc, J Boubnova, C Jacquier, S Irtan, A Breton, V Fouquet, A Guinot, T Lamireau, E Habonimana, A Schneider, F Elbaz, A Ranke, M L Poli-Merol, N Kalfa, T Petit, J-L Michel, P Buisson, J Lirussi-Borgnon, H Lardy, B Parmentier, C Cremillieux, F Schmitt, C Borderon, O Jaby, C Pelatan, P De Vries, M Pouzac-Arnould, C Grosos, J Breaud, C Tolg, Y Chaussy, C Laplace, E E Drumez, L Michaud, F Gottrand, V Houfflin-Debarge
OBJECTIVE: Evaluate the neonatal management and outcomes of neonates with prenatal diagnosis of esophageal atresia EA type A. METHODS: This population-based study was conducted using data from the French National Register for Infants with EA born from 2008 to 2014, including all cases of EA type A. We compared prenatal and neonatal characteristics and outcomes in children with prenatal diagnosis of EA type A to those with a postnatal diagnosis until the age of one...
May 8, 2018: Prenatal Diagnosis
https://www.readbyqxmd.com/read/29738345/the-esophageal-atresia-quality-of-life-questionnaires-feasibility-validity-and-reliability-in-sweden-and-germany
#16
Michaela Dellenmark-Blom, Jens Dingemann, Stefanie Witt, Julia H Quitmann, Linus Jönsson, Vladimir Gatzinsky, John E Chaplin, Monika Bullinger, Sofie Flieder, Benno M Ure, Carmen Dingemann, Kate Abrahamsson
OBJECTIVES: Esophageal atresia (EA) is a rare malformation characterized of discontinuity of the esophagus, concurrent with or without a tracheoesophageal fistula (TEF). We report the validity and reliability of a condition-specific quality of life (QOL) tool for EA/TEF children, the age-adapted EA-QOL-questionnaires, when used in Sweden and Germany. METHODS: 124 families of children with EA/TEF participated in the study; 53 parents completed the EA-QOL-questionnaire for children aged 2-7 years; 62 children/71 parents the EA-QOL-questionnaire for children 8-17 years...
May 5, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29733490/the-efficacy-of-serum-brain-natriuretic-peptide-for-the-early-detection-of-portopulmonary-hypertension-in-biliary-atresia-patients-before-liver-transplantation
#17
Koichiro Yoshimaru, Toshiharu Matsuura, Yoshiaki Takahashi, Yusuke Yanagi, Hazumu Nagata, Shouichi Ohga, Tomoaki Taguchi
Severe portopulmonary hypertension (POPH) is a contraindication for liver transplantation (LT) because of the high risk of postoperative heart failure. The early detection of POPH is important for patients with biliary atresia (BA). Brain natriuretic peptide (BNP) is known to be correlated with liver fibrosis in patients with liver cirrhosis. The aim of this study was to elucidate the efficacy of BNP measurement for the follow-up of patients with BA. Thirty-two patients with BA were identified from September 2011 to December 2016...
May 7, 2018: Pediatric Transplantation
https://www.readbyqxmd.com/read/29732364/impaired-fgf10-signaling-and-epithelial-development-in-experimental-lung-hypoplasia-with-esophageal-atresia
#18
Jun Wang, Hao Liu, Linlin Gao, Xiaomei Liu
Patients with esophageal atresia (EA) and tracheoesophageal fistula (TEF) often experience persistent respiratory tract disease. In experimental models, doxorubicin-induced developmental lung abnormalities may result from downregulation of branching morphogenesis factor fibroblast growth factor (Fgf10). This study investigated the temporospatial expression of Fgf10 pathway components and lung epithelial factors in an doxorubicin-induced EA-TEF model by quantitative polymerase chain reaction, immunohistochemistry, and immunoblotting...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29720579/congenital-esophageal-atresia-and-microtia-in-a-newborn-secondary-to-mycophenolate-mofetil-exposure-during-pregnancy-a-case-report-and-review-of-the-literature
#19
Musaed Mohammed Alsebayel, Faisal Abdulrahman Abaalkhail, Faisal Mohammed Alsebayel, Dema A Alissa, Ahmed Hamdan Al-Jedai, Hussien Elsiesy
BACKGROUND Mycophenolate mofetil (MMF) is one of the most commonly prescribed drugs to prevent organ transplant rejection in combination with calcineurin inhibitors and steroids. It has a different toxicity profile than tacrolimus and cyclosporine.  Gastrointestinal tract disturbances are the most common adverse effects. The use of MMF in pregnant women, however, holds great risk of miscarriage and fetal development defects such as external ear malformation, ocular anomalies, cleft lip and palate, and abnormality of distal limbs, heart, esophagus, and kidneys...
May 3, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29715697/epidemiology-and-outcome-of-major-congenital-malformations-in-a-large-german-county
#20
Boris Wittekindt, Rolf Schloesser, Nora Doberschuetz, Emilia Salzmann-Manrique, Jasmin Grossmann, Bjoern Misselwitz, Udo Rolle
INTRODUCTION:  Congenital malformations are associated with substantial neonatal morbidity and mortality. Furthermore, only sparse data are available on the modalities of care provided to and the associated clinical outcomes in affected neonates. In this study, we focused on five malformations that require surgery during the neonatal period: duodenal stenosis and atresia (DA), gastroschisis (GA), omphalocele (OM), congenital diaphragmatic herniation (CDH), and esophageal atresia (EA)...
May 1, 2018: European Journal of Pediatric Surgery
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