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https://www.readbyqxmd.com/read/28445309/exploring-spatial-patterns-of-acupoint-indications-from-clinical-data-a-strobe-compliant-article
#1
Won-Mo Jung, Soon-Ho Lee, Ye-Seul Lee, Younbyoung Chae
Every acupoint has specific indications for acupuncture treatment. These indications, primarily established based on the meridian system, have spatial patterns of symptoms on the human body. We investigated the associations between acupoints and symptom locations in 75 patients with chronic pain who were asked to sketch the localization of their symptoms on body schemes using the bodily sensation map (BSM) system. Combining the BSM and clinical information, we estimated the statistical parameters of relationships between acupoints and spatial information on symptoms...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28444763/manganese-concentration-mapping-in-the-rat-brain-with-mri-pet-and-autoradiography
#2
Geoffrey J Topping, Andrew Yung, Paul Schaffer, Cornelia Hoehr, Rick Kornelsen, Piotr Kozlowski, Vesna Sossi
PURPOSE: Mn(2+) is used a contrast agent and marker for neuronal activity with magnetic resonance imaging (MRI) in rats and mice, but its accumulation is generally not assessed quantitatively. In this work, non-radioactive Mn and (52) Mn are injected simultaneously in rats, and imaged with MRI, positron emission tomography (PET) and autoradiography (AR). Mn distributions are compared between modalities, to assess the potential and limitations on quantification of Mn with MRI, and to investigate the potential of multimodal measurement of Mn accumulation...
April 26, 2017: Medical Physics
https://www.readbyqxmd.com/read/28435415/the-gold-coast-integrated-care-model
#3
Martin Connor, Helen Cooper, Anne McMurray
This article outlines the development of the Australian Gold Coast Integrated Care Model based on the elements identified in contemporary research literature as essential for successful integration of care between primary care, and acute hospital services. The objectives of the model are to proactively manage high risk patients with complex and chronic conditions in collaboration with General Practitioners to ultimately reduce presentations to the health service emergency department, improve the capacity of specialist outpatients, and decrease planned and unplanned admission rates...
July 8, 2016: International Journal of Integrated Care
https://www.readbyqxmd.com/read/28435102/simultaneous-time-interleaved-multislice-stims-for-rapid-susceptibility-weighted-acquisition
#4
Berkin Bilgic, Huihui Ye, Lawrence L Wald, Kawin Setsompop
T2⁎ weighted 3D Gradient Echo (GRE) acquisition is the main sequence used for Susceptibility Weighted Imaging (SWI) and Quantitative Susceptibility Mapping (QSM). These applications require a long echo time (TE) to build up phase contrast, requiring a long repetition time (TR), and leading to excessively lengthy scans. The long TE acquisition creates a significant amount of unused time within each TR, which can be utilized for either multi-echo sampling or additional image encoding with the echo-shift technique...
April 20, 2017: NeuroImage
https://www.readbyqxmd.com/read/28433835/the-relationship-between-pre-verbal-event-representations-and-semantic-structures-the-case-of-goal-and-source-paths
#5
Laura Lakusta, Danielle Spinelli, Kathryn Garcia
We explored the nature of infants' concepts for goal path and source path in motion events (e.g., the duck moved into the bowl/out of the bowl), specifically asking how infants' representations could support the acquisition of the semantic roles of goal path and source path in language. The results showed that 14.5-month-old infants categorized goal paths across different motion events (moving to X, moving on Y), and they also categorized source paths if the source reference objects were highly salient (relatively large in size and colorful)...
April 20, 2017: Cognition
https://www.readbyqxmd.com/read/28427547/qualitative-evaluation-of-the-st-george-s-respiratory-questionnaire-in-patients-with-severe-asthma
#6
Linda M Nelsen, Miriam Kimel, Lindsey T Murray, Hector Ortega, Sarah M Cockle, Steven W Yancey, Guy Brusselle, Frank C Albers, Paul W Jones
PURPOSE: Content validity is the extent to which a patient-reported outcome measure evaluates the concepts most relevant to a patient's condition and treatment. The St George's Respiratory Questionnaire (SGRQ) has been validated in a range of respiratory conditions. This study evaluated the content validity of the SGRQ in patients with severe asthma. METHODS: A qualitative study, guided by a protocol, which included concept elicitation and cognitive debriefing of the SGRQ, was conducted in patients aged ≥18 years with history of severe asthma and blood eosinophil counts of ≥150/μL (past month) or ≥300/μL (past 12 months)...
May 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28424799/role-of-psychological-resilience-on-health-outcomes-in-hospitalized-patients-with-acute-illness-a-scoping-review
#7
Elen Marged Bradley-Roberts, Christian P Subbe
Recovery from Acute Illness is dependent on severity of illness. We aimed to investigate whether resilience as the 'ability to bounce back' might also affect recovery. We conducted a scoping review to identify gaps in the existing literature. We used emergency care, intensive care, critical care and trauma as surrogates for acute illness. We mapped synonyms for resilience and selected 'resilience' and 'robustness'. The search was limited to adult patients admitted to hospitals. We found strong evidence for psychological sequelae of acute illness but no research focusing specifically on the concepts of resilience or robustness and no interventional studies in the acute hospital setting...
2017: Acute Medicine
https://www.readbyqxmd.com/read/28423835/snomed-ct-as-reference-terminology-in-the-danish-national-home-care-documentation-standard
#8
Kirstine Rosenbeck Gøeg, Pia Britt Elberg, Anne Randorff Højen, Ulla Lund Eskildsen
In Danish home care, multiple professions deliver services to citizens. FSIII is a national home care documentation standard, where one of the goals is to share documentation to improve coordination between these professional groups and avoid double documentation. The aim of this study was to develop a SNOMED-CT based navigation hierarchy to ensure that professions could preserve their documentation practice, to help avoid double documentation, and to ensure that the technical implementation did not require sophisticated semantic tools...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28423796/personalized-guideline-based-treatment-recommendations-using-natural-language-processing-techniques
#9
Matthias Becker, Britta Böckmann
Clinical guidelines and clinical pathways are accepted and proven instruments for quality assurance and process optimization. Today, electronic representation of clinical guidelines exists as unstructured text, but is not well-integrated with patient-specific information from electronic health records. Consequently, generic content of the clinical guidelines is accessible, but it is not possible to visualize the position of the patient on the clinical pathway, decision support cannot be provided by personalized guidelines for the next treatment step...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28422654/novel-mri-technique-enables-non-invasive-measurement-of-atrial-wall-thickness
#10
Marta Varela, Ross Morgan, Adeline Theron, Desmond Dillon-Murphy, Henry Chubb, John Whitaker, Markus Henningsson, Paul Aljabar, Tobias Schaeffter, Christoph Kolbitsch, Oleg V Aslanidi
Knowledge of atrial wall thickness (AWT) has the potential to provide important information for patient stratification and the planning of interventions in atrial arrhythmias. To date, information about AWT has only been acquired in post-mortem or poor-contrast CT studies, providing limited coverage and highly variable estimates of AWT. We present a novel contrast agent-free MRI sequence for imaging AWT and use it to create personalized AWT maps and a biatrial atlas. A novel black-blood phase-sensitive inversion recovery protocol was used to image 10 volunteers and 2 atrial fibrillation patients, as proof of concept...
April 13, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28421179/synergy-based-bilateral-port-a-universal-control-module-for-tele-manipulation-frameworks-using-asymmetric-master-slave-systems
#11
Anais Brygo, Ioannis Sarakoglou, Giorgio Grioli, Nikos Tsagarakis
Endowing tele-manipulation frameworks with the capability to accommodate a variety of robotic hands is key to achieving high performances through permitting to flexibly interchange the end-effector according to the task considered. This requires the development of control policies that not only cope with asymmetric master-slave systems but also whose high-level components are designed in a unified space in abstraction from the devices specifics. To address this dual challenge, a novel synergy port is developed that resolves the kinematic, sensing, and actuation asymmetries of the considered system through generating motion and force feedback references in the hardware-independent hand postural synergy space...
2017: Frontiers in Bioengineering and Biotechnology
https://www.readbyqxmd.com/read/28420607/the-research-progress-of-farm-animal-genomics-based-on-sequencing-technologies
#12
Liang Suyun, Zhou Zhengkui, Hou Shuisheng
Various farm animal breeds have been domesticated and bred for thousands years, and they provide adequate animal-derived proteins to meet the human nutrition requirement. Although quantitative genetics was applied in animal breeding, which launched a technological revolution in the past century, a number of complex traits remain difficult to be selected based on pedigree derived breeding, due to complicated animal genetics and development mechanisms. Farm animal's genetic potential hasn't yet to be fully exploited...
April 20, 2017: Yi Chuan, Hereditas
https://www.readbyqxmd.com/read/28418811/hypertrabeculated-left-ventricular-myocardium-in-relationship-to-myocardial-function-and-fibrosis-the-multi-ethnic-study-of-atherosclerosis
#13
Nadine Kawel-Boehm, Robyn L McClelland, Filip Zemrak, Gabriella Captur, W Gregory Hundley, Chia-Ying Liu, James C Moon, Steffen E Petersen, Bharath Ambale-Venkatesh, João A C Lima, David A Bluemke
Purpose To determine if excess greater left ventricle (LV) trabeculation is associated with decreased average regional myocardial function, diffuse fibrosis, or both. Materials and Methods This was a HIPAA-compliant institutional board approved multicenter study, and all participants provided written informed consent. Participants in the Multi-Ethnic Study of Atherosclerosis (MESA) underwent a comprehensive cardiac magnetic resonance (MR) examination. LV trabeculation was measured with the maximal apical fractal dimension (FD), which is a marker of endocardial complexity...
April 17, 2017: Radiology
https://www.readbyqxmd.com/read/28418061/self-powered-electrochemical-systems-as-neurochemical-sensors-toward-self-triggered-in-vivo-analysis-of-brain-chemistry
#14
Fei Wu, Ping Yu, Lanqun Mao
Real-time in vivo analysis of neurochemical dynamics has great physiological and pathological implications for a full understanding of the brain. Self-powered electrochemical systems (SPESs) built on galvanic cell configurations bear the advantages of easy miniaturization for implantation and no interference to electric activities of neurons over traditional externally-powered electrochemical sensors for self-triggered in vivo analysis. However, this is still a new concept for in vivo neurochemical sensing with few implanted examples reported so far...
April 18, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/28416459/the-error-of-broca-from-the-traditional-localizationist-concept-to-a-connectomal-anatomy-of-human-brain
#15
REVIEW
Hugues Duffau
Neurology, especially aphasiology, was mainly built on behavioral-structural correlations ("lesion method"). In this setting, Broca's area has been considered as the "speech area"; moreover, this observation led to localizationism. However, advances in brain mapping techniques, as functional neuroimaging and direct electrical stimulation in patients undergoing awake surgery for gliomas, has resulted in a paradigmatic shift regarding models of neural architecture. In fact, the brain is organized in distributed complex networks underpinning sensorimotor, visuospatial, language, cognitive and emotional functions...
April 14, 2017: Journal of Chemical Neuroanatomy
https://www.readbyqxmd.com/read/28414998/a-qualitative-study-on-using-concept-maps-in-problem-based-learning
#16
Zenobia C Y Chan
BACKGROUND: The visual arts, including concept maps, have been shown to be effective tools for facilitating student learning. However, the use of concept maps in nursing education has been under-explored. OBJECTIVES: The aim of this study was to explore how students develop concept maps and what these concept maps consist of, and their views on the use of concept maps as a learning activity in a PBL class. DESIGN: A qualitative approach consisting of an analysis of the contents of the concept maps and interviews with students...
April 12, 2017: Nurse Education in Practice
https://www.readbyqxmd.com/read/28414731/a-hyper-temporal-remote-sensing-protocol-for-high-resolution-mapping-of-ecological-sites
#17
Jonathan J Maynard, Jason W Karl
Ecological site classification has emerged as a highly effective land management framework, but its utility at a regional scale has been limited due to the spatial ambiguity of ecological site locations in the U.S. or the absence of ecological site maps in other regions of the world. In response to these shortcomings, this study evaluated the use of hyper-temporal remote sensing (i.e., hundreds of images) for high spatial resolution mapping of ecological sites. We posit that hyper-temporal remote sensing can provide novel insights into the spatial variability of ecological sites by quantifying the temporal response of land surface spectral properties...
2017: PloS One
https://www.readbyqxmd.com/read/28414331/a-new-fate-mapping-system-reveals-context-dependent-random-or-clonal-expansion-of-microglia
#18
Tuan Leng Tay, Dominic Mai, Jana Dautzenberg, Francisco Fernández-Klett, Gen Lin, Sagar, Moumita Datta, Anne Drougard, Thomas Stempfl, Alberto Ardura-Fabregat, Ori Staszewski, Anca Margineanu, Anje Sporbert, Lars M Steinmetz, J Andrew Pospisilik, Steffen Jung, Josef Priller, Dominic Grün, Olaf Ronneberger, Marco Prinz
Microglia constitute a highly specialized network of tissue-resident immune cells that is important for the control of tissue homeostasis and the resolution of diseases of the CNS. Little is known about how their spatial distribution is established and maintained in vivo. Here we establish a new multicolor fluorescence fate mapping system to monitor microglial dynamics during steady state and disease. Our findings suggest that microglia establish a dense network with regional differences, and the high regional turnover rates found challenge the universal concept of microglial longevity...
April 17, 2017: Nature Neuroscience
https://www.readbyqxmd.com/read/28412593/bootstrapping-language-acquisition
#19
Omri Abend, Tom Kwiatkowski, Nathaniel J Smith, Sharon Goldwater, Mark Steedman
The semantic bootstrapping hypothesis proposes that children acquire their native language through exposure to sentences of the language paired with structured representations of their meaning, whose component substructures can be associated with words and syntactic structures used to express these concepts. The child's task is then to learn a language-specific grammar and lexicon based on (probably contextually ambiguous, possibly somewhat noisy) pairs of sentences and their meaning representations (logical forms)...
April 13, 2017: Cognition
https://www.readbyqxmd.com/read/28412435/cmr-derived-extracellular-volume-fraction-as-a-marker%C3%A2-for-myocardial-fibrosis-the-importance-of-coexisting-myocardial-inflammation
#20
Julia Anna Lurz, Christian Luecke, David Lang, Christian Besler, Karl-Philipp Rommel, Karin Klingel, Reinhard Kandolf, Volker Adams, Katharina Schöne, Gerhard Hindricks, Gerhard Schuler, Axel Linke, Holger Thiele, Matthias Gutberlet, Philipp Lurz
OBJECTIVES: The aim of the present study was to evaluate whether extracellular volume fraction (ECV) can reliably inform on the extent of diffuse fibrosis in the simultaneous presence of myocardial inflammation, which has not been verified to date. BACKGROUND: Diffuse myocardial fibrosis is associated with unfavorable outcome in patients with cardiomyopathy, and is of prognostic relevance. Assessment of ECV bears promise for being a noninvasive surrogate parameter, but it may be altered by other pathologies...
April 7, 2017: JACC. Cardiovascular Imaging
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