keyword
MENU ▼
Read by QxMD icon Read
search

Cervical cancer gynecologic

keyword
https://www.readbyqxmd.com/read/29664848/morbidity-and-mortality-risk-assessment-in-gynecologic-oncology-surgery-using-the-american-college-of-surgeons-national-surgical-quality-improvement-program-database
#1
Adrian Kohut, Theofano Orfanelli, Juan Lucas Poggio, Darlene Gibbon, Alexandre Buckley De Meritens, Scott Richard
INTRODUCTION: Gynecologic oncology patients represent a distinct patient population with a variety of surgical risks. The American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) database provides an opportunity to analyze large cohorts of patients over extended periods with high accuracy. Our goal was to develop a postoperative risk assessment calculator capable of providing a standardized, objective means of preoperatively identifying high-risk patients in the gynecologic oncology population...
April 16, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29662648/visceral-abdominal-fat-measured-by-computer-tomography-as-a-prognostic-factor-for-gynecological-malignancies
#2
Johanna Nattenmüller, Joachim Rom, Tom Buckner, Jalal Arvin, Benedikt Bau, Christof Sohn, Hans-Ulrich Kauczor, Sarah Schott
Introduction: Obesity is associated with increased incidence of ovarian (OC), cervical (CC) and endometrium cancer (EC). However, the impact of body composition (BC) on overall survival (OS), especially of visceral adipose tissue (VAT) is not yet understood. Methods: In 189 women with gynecological malignancies (31 OC, 104 CC, 54 EC, mean age 62.9y; mean BMI 26.8 kg/m2 ; median follow-up 30.7months) with routine staging CT-scans at baseline (mean interval: 4.3 months), densitometric quantification of total (TAT), visceral, and subcutaneous-fat-area (SAT), inter-muscular-fat-area (IMFA), and skeletal-muscle-index (SMI) was performed to analyze the impact of BC on survival...
March 27, 2018: Oncotarget
https://www.readbyqxmd.com/read/29661497/postoperative-chemotherapy-for-node-positive-cervical-cancer-results-of-a-multicenter-phase-ii-trial-jgog1067
#3
Maki Matoda, Nobuhiro Takeshima, Hirofumi Michimae, Takashi Iwata, Harushige Yokota, Yutaka Torii, Yorito Yamamoto, Kazuhiro Takehara, Shin Nishio, Hirokuni Takano, Mika Mizuno, Yoshiyuki Takahashi, Yuji Takei, Tetsuya Hasegawa, Mikio Mikami, Takayuki Enomoto, Daisuke Aoki, Toru Sugiyama
OBJECTIVE: This multicenter phase II Japanese Gynecologic Oncology Group study (JGOG1067) was designed to evaluate the efficacy and safety of postoperative chemotherapy in patients with node-positive cervical cancer. METHODS: Patients with stage IB-IIA squamous cervical cancer who underwent radical hysterectomy and were confirmed to have pelvic lymph node metastasis were eligible for this study. The patients postoperatively received irinotecan (CPT-11; 60mg/m2 intravenously on days 1 and 8) and nedaplatin (NDP; 80mg/m2 intravenously on day 1)...
April 13, 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29650191/supportive-care-needs-and-quality-of-life-of-patients-with-gynecological-cancer-undergoing-therapy
#4
Riska Hediya Putri, Yati Afiyanti, Titin Ungsianik, Ariesta Milanti
OBJECTIVE: To identify the relationship of unmet supportive care needs with quality of life of patients with gynecological cancer undergoing therapy. METHOD: This study used a cross-sectional design. A total of 153 patients with gynecological cancer undergoing therapy were recruited using consecutive sampling methods. The participants completed the questionnaire of Supportive Care Needs Survey to identify their supportive care needs, EORTC-QLQ 30 to assess their general quality of life, and EORTC-QLQ-CX 24 or - OV 28 to determine cancer-specific quality of life in cervical cancer and ovarian cancer, respectively...
February 2018: Enfermería Clínica
https://www.readbyqxmd.com/read/29649025/risk-of-anal-cancer-in-women-with-a-human-papillomavirus-related-gynecological-neoplasm-puerto-rico-1987-2013
#5
Adrianna I Acevedo-Fontánez, Erick Suárez, Carlos R Torres Cintrón, Ana P Ortiz
OBJECTIVE: The aim of the study was to estimate the magnitude of the association between HPV-related gynecological neoplasms and secondary anal cancer among women in Puerto Rico (PR). MATERIALS AND METHODS: We identified 9,489 women who had been diagnosed with a primary cervical, vaginal, or vulvar tumor during 1987-2013. To describe the trends of invasive cervical, vulvar, vaginal, and anal cancer, the age-adjusted incidence rates were estimated using the direct method (2000 US as Standard Population)...
April 11, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29643871/an-examination-of-the-sexual-functions-of-patients-who-underwent-a-gynecologic-cancer-operation-and-received-brachytherapy
#6
Ozlem Guner, Sureyya Gumussoy, Nigar Celik, Aynur Saruhan, Oya Kavlak
Objective: This study was planned as a descriptive study for the purpose of examining the sexual functions of patients' who underwent a gynecological operation and received brachytherapy. Methods: The study was conducted with 118 women who attended the Radiation Oncology Unit at Ege University Medical Faculty Hospital in Izmir Province for Gynecological Oncology follow-up, who participated voluntarily and were assigned using the random sampling method. The participants were married, sexually active, had a diagnosis of gynecologic cancer, underwent an operation and received brachytherapy for four months after the operation...
January 2018: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29642758/identification-of-significant-gene-signatures-and-prognostic-biomarkers-for-patients-with-cervical-cancer-by-integrated-bioinformatic-methods
#7
Xiaofang Li, Run Tian, Hugh Gao, Feng Yan, Le Ying, Yongkang Yang, Pei Yang, Yan'e Gao
Cervical cancer is the leading cause of death with gynecological malignancies. We aimed to explore the molecular mechanism of carcinogenesis and biomarkers for cervical cancer by integrated bioinformatic analysis. We employed RNA-sequencing details of 254 cervical squamous cell carcinomas and 3 normal samples from The Cancer Genome Atlas. To explore the distinct pathways, messenger RNA expression was submitted to a Gene Set Enrichment Analysis. Kyoto Encyclopedia of Genes and Genomes and protein-protein interaction network analysis of differentially expressed genes were performed...
January 1, 2018: Technology in Cancer Research & Treatment
https://www.readbyqxmd.com/read/29625422/paclitaxel-and-di-fluorinated-curcumin-loaded-in-albumin-nanoparticles-for-targeted-synergistic-combination-therapy-of-ovarian-and-cervical-cancers
#8
Kaustubh A Gawde, Samaresh Sau, Katyayani Tatiparti, Sushil K Kashaw, Mohammad Mehrmohammadi, Asfar S Azmi, Arun K Iyer
Paclitaxel (PTX) encapsulated in albumin (Abraxane® ) is an FDA approved frontline nano-formulation for treating advance metastatic pancreatic, lung and breast cancers. Currently in clinic, Abraxane® is being used as a one of the components of combination therapy regimens. On the other hand, difluorinated curcumin (CDF) is a novel and potent synthetic curcumin analogue that is being evaluated for several malignancies including pancreatic, liver, ovarian and breast cancers. To improve the bioavailability and targeting ability of hydrophobic PTX and CDF, we have encapsulated them in folic acid decorated bovine serum albumin nanoparticles, namely FA-BSA-PTX and FA-BSA-CDF, respectively...
March 28, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29621762/mifepristone-inhibits-the-migration-of-cervical-cancer-cells-by-inhibiting-exocrine-secretion
#9
Lin Sang, Xiaoyan Wang, Xingbo Zhao
Cervical cancer (CC) is one of the most common gynecological malignancies, and metastasis limits the use of surgical resection. Metapristone (MIF) was reported to suppress the proliferation and migration of several cancer cells. Exosomes play a variety of roles in cellular biological processes. The relation of exosomes and CC is less studied. Cell viability, apoptosis assay and migration assay was conducted in HeLa cells treated by MIF by CCK-8 kit, staining by Annexin V-fluorescein isothiocyanate and propidium iodide, and wound test respectively...
April 5, 2018: Pharmacology
https://www.readbyqxmd.com/read/29621040/concomitant-repair-of-pelvic-floor-disorders-in-women-undergoing-surgery-for-gynecologic-malignancies
#10
Katarzyna Bochenska, Margaret Mueller, Julia Geynisman-Tan, Alix Leader-Cramer, Bhumy Davé, Christina Lewicky-Gaupp, Kimberly Kenton
OBJECTIVE: The aims of this study were to determine the rate and describe 30-day postoperative complications of concomitant pelvic organ prolapse and/or urinary incontinence (POPUI) procedures in women undergoing surgery for a gynecologic malignancy. METHODS: Women who underwent surgical intervention for a gynecologic malignancy between 2010 and 2014 were identified using postoperative International Classification of Diseases, Ninth Revision codes 179.0 to 184.9 in the American College of Surgeons National Surgical Quality Improvement Program database...
April 4, 2018: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/29620659/individualized-pelvic-lymphadenectomy-should-follow-neoadjuvant-concurrent-chemoradiotherapy-for-locally-advanced-cervical-cancer
#11
Li-Chun Wei, Xin Li, Ying Zhang, Yun-Zhi Dang, Wei-Wei Li, Jian-Ping Li, Li-Na Zhao, Shu-Juan Liu, Xia Li, Mei Shi
To study the outcomes following concurrent chemoradiotherapy (CCRT) and subsequent radical surgery for locally advanced cervical cancer (LACC), analyze the relationship between imaging-diagnosed and postoperative-diagnosed lymph node (LN) involvement, and identify patients who would benefit from individualized pelvic lymphadenectomy.We retrospectively reviewed records of 410 patients who underwent CCRT followed by radical surgery for International Federation of Gynecology and Obstetrics Stage Ib2-IIIb disease...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29620291/integrated-analysis-of-long-non%C3%A2-coding-rna-competing-interactions-revealed-potential-biomarkers-in-cervical-cancer-based-on-a-public-database
#12
Wen-Juan Wu, Yang Shen, Jing Sui, Cheng-Yun Li, Sheng Yang, Si-Yi Xu, Man Zhang, Li-Hong Yin, Yue-Pu Pu, Ge-Yu Liang
Cervical cancer (CC) is a common gynecological malignancy in women worldwide. Using an RNA sequencing profile from The Cancer Genome Atlas (TCGA) and the CC patient information, the aim of the present study was to identify potential long non‑coding RNA (lncRNA) biomarkers of CC using bioinformatics analysis and building a competing endogenous RNA (ceRNA) co‑expression network. Results indicated several CC‑specific lncRNAs, which were associated with CC clinical information and selected some of them for validation and evaluated their diagnostic values...
April 5, 2018: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29616651/knowledge-and-practice-of-togolese-women-concerning-cervical-cancer
#13
S Agbo, H S Bemanana, K M Aziagbenyo, F M Lahaye
OBJECTIVE: To identify the determinants of the knowledge and practice of Togolese women concerning cervical cancer. METHODS: This cross-sectional study with a descriptive and analytical focus took place in Togo during the four-month period from May to August 2016 and surveyed women aged 18 to 60 living in the Lomé municipal area for at least 12 months. Sampling of the intervention zones was based on reasoned choice depending on the availability of health structures in the area...
February 1, 2018: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/29614248/comparative-testing-of-hpv-l1-protein-monoclonal-antibody-panel-for-the-detection-of-hpv-in-cervical-exfoliated-cells
#14
Le Wang, Yu-Chang Hu, Chang-Yi Xiao, Fei Wang, Yu-Fei Liu, Li-Hua Tang, Rong-Shuang Xiao
AIMS: To determine the value of a monoclonal antibody panel against a C-terminal conserved sequence polypeptide of human papillomavirus (HPV) L1 (a major capsid protein) for the detection of HPV in cervical exfoliated cells, as well as the potential of this antibody panel to be developed into an assay kit for the clinical screening of cervical cancer. METHODS: Cervical exfoliated cells were collected at a gynecology clinic. One part of each sample was sent to the Department of Pathology for HPV genotyping, and the other part was sent to the Department of Pathology for cytologic testing and then to the laboratory for immunological histological chemistry (IHC) assay in which an HPV L1 C-terminal conserved sequence polypeptide-induced mouse monoclonal antibody panel was used to detect HPV L1...
March 31, 2018: Journal of Virological Methods
https://www.readbyqxmd.com/read/29605054/investigating-black-white-disparities-in-gynecologic-oncology-theories-conceptual-models-and-applications
#15
REVIEW
Kemi M Doll
Within gynecologic oncology are two of the top five widest Black-White mortality gaps among all cancer diagnoses in the United States. A rich body of work from the social sciences, including anthropology, sociology and social epidemiology, have broadened the understanding of and research approaches to the study of health and healthcare inequity experienced by Black Americans. Yet, these intellectual advancements in understanding are virtually absent from the gynecologic oncology literature. The goal of this analytic essay will be to introduce three current frameworks of studying racial inequity: The Ecosocial Theory of Disease Distribution, The Fundamental Cause Theory, and The Public Health Critical Race Praxis...
April 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29605053/a-contemporary-framework-of-health-equity-applied-to-gynecologic-cancer-care-a-society-of-gynecologic-oncology-evidenced-based-review
#16
REVIEW
Sarah M Temkin, B J Rimel, Amanda S Bruegl, Camille C Gunderson, Anna L Beavis, Kemi M Doll
Health disparities are defined as the preventable difference in the burden of disease, injury, and violence, or opportunity to achieve optimal health that socially disadvantaged populations experience compared to the population as a whole. Disparities in incidence and cancer outcomes for women with gynecologic malignancies have been well described particularly for American women of Black race. The etiology of these disparities has been tied to socio-economics, cultural, educational and genetic factors. While access to high quality treatment has been primarily linked to survival from cervical and ovarian cancer, innate biologic distinctions have been principally cited as reasons for differences in incidence and mortality in cancers of the uterine corpus...
April 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29605048/racial-and-ethnic-disparities-over-time-in-the-treatment-and-mortality-of-women-with-gynecological-malignancies
#17
J Alejandro Rauh-Hain, Alexander Melamed, Diego Schaps, Amy J Bregar, Ryan Spencer, John O Schorge, Laurel W Rice, Marcela G Del Carmen
OBJECTIVE: To examine temporal trends in treatment and survival among black, Asian, Hispanic, and white women diagnosed with endometrial, ovarian, cervical, and vulvar cancer. METHODS: Using the National Cancer Database (2004-2014), we identified women diagnosed with endometrial, ovarian, cervical, and vulvar cancer. For each disease site, we analyzed race/ethnicity-specific trends in receipt of evidence-based practices. Professional societies' recommendations were used to define these practices...
April 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29602377/-the-spanish-society-of-cytology-quality-control-program-of-gynecological-cytology
#18
Francesc Alameda, Sonsoles Aso, Inmaculada Catalina, M Dolores Comes, M Carmen Gomez Mateo, Rosario Granados, Belén Lloveras, Rosa Oncins, Marta Rezola Bajineta, Francesc Treserra
INTRODUCTION: In Spain, the guidelines for cervical cancer screening include a recommendation to enroll in external quality control programs. The Spanish Society of Cytology (SEC) has initiated its own quality control program of gynecological cytology (QCPGC). AIM: To describe and discuss the results of the second round of SEĆs QCPGC. MATERIAL AND METHOD: The cases are selected by a group of expert cytologists. The cases with an agreement of 75% of four cytopathologists were used...
April 2018: Revista Española de Patología
https://www.readbyqxmd.com/read/29574539/cervical-cancer-patients-willingness-and-ability-to-serve-as-health-care-educators-to-advocate-for-human-papillomavirus-vaccine-uptake
#19
Ilene G Ladd, Radhika P Gogoi, Tyler L Bogaczyk, Sharon L Larson
Human papillomavirus (HPV) causes nearly all cervical cancer. Only half of females and less than half of males receive the recommended HPV vaccine dose. This study explores whether cervical cancer patients may serve as health advocates to adolescents and their parents in encouraging the uptake of the HPV vaccine. The study targeted an opportunity sample of women seen in the gynecology oncology clinic with a diagnosis of cervical cancer. During interviews, patients were asked about the following: provider conversations regarding cervical cancer, knowledge of HPV and the vaccine, discussions with family or friends about the causes or prevention of cervical cancer, and whether they would be willing to talk with others about the HPV vaccine...
March 25, 2018: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/29571035/prevalence-and-age-wise-distribution-of-human-papillomavirus-type-16-18-infections-among-hospital-screened-women-of-a-peri-urban-area-in-west-bengal-impact-of-socio-demographic-factors
#20
Amrapali Bhattacharya, Shrinka Sen, Paramita Mandal, Sweta Sharma Saha, Somosree Sarkar, Om Prakash Pathak, Lena Biswas, Jayeeta Roy, Rimpa Banerjee, Ranita Roy Chowdhury, Manidip Pal, Ankur Mukherjee, Sharmila Sengupta
BACKGROUND: We undertook the current study on cervical Human Papillomavirus (HPV) prevalence along with cytology in women visiting the Gynecology Out-patient Department of a hospital for common gynecological ailments, subsequent to our earlier population-based study on HPV prevalence from India. METHODS: We analyzed data on cervical-cytology (Pap smears) and PCR-based molecular detection of HPV infection along with socio-demographic variables (N = 696). RESULTS: We identified 36...
March 20, 2018: Cancer Epidemiology
keyword
keyword
100339
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"