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https://www.readbyqxmd.com/read/28063287/clinical-practice-guidelines-for-the-use-of-video-capsule%C3%A2-endoscopy
#1
Robert A Enns, Lawrence Hookey, David Armstrong, Charles N Bernstein, Steven J Heitman, Christopher Teshima, Grigorios I Leontiadis, Frances Tse, Daniel Sadowski
BACKGROUND & AIMS: Video capsule endoscopy (CE) provides a noninvasive option to assess the small intestine, but its use with respect to endoscopic procedures and cross-sectional imaging varies widely. The aim of this consensus was to provide guidance on the appropriate use of CE in clinical practice. METHODS: A systematic literature search identified studies on the use of CE in patients with Crohn's disease, celiac disease, gastrointestinal bleeding, and anemia...
January 4, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28061830/age-nutrition-chirugie-anc-study-impact-of-a-geriatric-intervention-on-the-screening-and-management-of-undernutrition-in-elderly-patients-operated-on-for-colon-cancer-a-stepped-wedge-controlled-trial
#2
Marine Dupuis, Elisabetta Kuczewski, Laurent Villeneuve, Sylvie Bin-Dorel, Max Haine, Claire Falandry, Thomas Gilbert, Guillaume Passot, Olivier Glehen, Marc Bonnefoy
BACKGROUND: Undernutrition prior to major abdominal surgery is frequent and increases morbidity and mortality, especially in older patients. The management of undernutrition reduces postoperative complications. Nutritional management should be a priority in patient care during the preoperative period. However undernutrition is rarely detected and the guidelines are infrequently followed. Preoperative undernutrition screening should allow a better implementation of the guidelines. METHODS/DESIGN: The ANC ("Age Nutrition Chirurgie") study is an interventional, comparative, prospective, multicenter, randomized protocol based on the stepped wedge trial design...
January 7, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28050138/adjuvant-systemic-chemotherapy-for-stages-ii-and-iii-colon-cancer-after-complete-resection-a-clinical-practice-guideline
#3
B M Meyers, R Cosby, F Quereshy, D Jonker
BACKGROUND: Updated practice guidelines on adjuvant chemotherapy for completely resected colon cancer are lacking. In 2008, Cancer Care Ontario's Program in Evidence-Based Care developed a guideline on adjuvant therapy for stages ii and iii colon cancer. With newer regimens being assessed in this patient population and older agents being either abandoned because of non-effectiveness or replaced by agents that are more efficacious, a full update of the original guideline was undertaken...
December 2016: Current Oncology
https://www.readbyqxmd.com/read/28035461/is-early-colonoscopy-after-ct-diagnosed-diverticulitis-still-necessary
#4
Thomas Surya Suhardja, Shana Norhadi, Edward Zhenyu Seah, Stephen Rodgers-Wilson
PURPOSE: WHO GLOBOCAN 2012 data showed that Australia and New Zealand have the highest incidence rates of colorectal cancer in the world (Ferlay et al. 1). Current guidelines recommend that patients admitted for an episode of acute diverticulitis require an early follow-up colonoscopy to rule out colorectal malignancy as reported by Fozard et al. (Colorectal Dis 13:1-11, 2011). Recent studies however have indicated that this may not be warranted (Brar et al. Dis Colon rectum 56:1259-1264, 2013)...
December 29, 2016: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28027818/laparoscopic-colectomy-for-cancer-improved-compliance-with-guidelines-for-chemotherapy-and-survival
#5
Roger H Kim, Mindie M Kavanaugh, Gloria C Caldito
BACKGROUND: Laparoscopic surgery for colon cancer has been demonstrated in clinical trials to have short-term benefits when compared to the open surgical approach. Guidelines of the National Comprehensive Cancer Network recommend that patients with stage III or high-risk stage II colon cancer undergo adjuvant chemotherapy. We hypothesized that laparoscopic colectomy is associated with increased compliance to recommendations for chemotherapy, a lesser time to start of chemotherapy, and increased overall survival...
December 24, 2016: Surgery
https://www.readbyqxmd.com/read/28025627/patients-with-acromegaly-presenting-with-colon-cancer-a-case-series
#6
Murray B Gordon, Samer Nakhle, William H Ludlam
Introduction. Frequent colonoscopy screenings are critical for early diagnosis of colon cancer in patients with acromegaly. Case Presentations. We performed a retrospective analysis of the incidental diagnoses of colon cancer from the ACCESS trial (ClinicalTrials.gov identifier: NCT01995734). Colon cancer was identified in 2 patients (4.5%). Case  1 patient was a 36-year-old male with acromegaly who underwent transsphenoidal surgery to remove the pituitary adenoma. After surgery, the patient underwent routine colonoscopy screening, which revealed a 40 mm tubular adenoma in the descending colon...
2016: Case Reports in Endocrinology
https://www.readbyqxmd.com/read/27996215/prognostic-impact-of-the-length-of-the-longitudinal-resection-margin-in-colon-cancer
#7
Soo Young Lee, Chang Hyun Kim, Young Jin Kim, Hyeong Rok Kim
AIM: Although several guidelines recommend a longitudinal resection margin (LRM) of at least a five centimetres, the impact of the LRM on survival is still unknown. The study assessed the prognostic significance of the LRM in patients with colon cancer. METHOD: We retrospectively reviewed 1343 primary colon cancer patients without distant metastasis who underwent curative resection between January 2004 and December 2012. Patients were classified into three groups: LRM <3 cm (n = 186), LRM ≥3 and <5 cm (n = 376), and LRM ≥5 cm (n = 781)...
December 20, 2016: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/27956537/neoadjuvant-therapy-for-rectal-cancer-affects-lymph-node-yield-and-status-without-clear-implications-on-outcome-the-case-for-eliminating-a-metric-and-using-preoperative-staging-to-guide-therapy
#8
Sherif R Z Abdel-Misih, Lai Wei, Al B Benson, Steven Cohen, Lily Lai, John Skibber, Neal Wilkinson, Martin Weiser, Deborah Schrag, Tanios Bekaii-Saab
BACKGROUND: Nodal status has long been considered pivotal to oncologic care, staging, and management. This has resulted in the establishment of rudimentary metrics regarding adequate lymph node yield in colon and rectal cancers for accurate cancer staging. In the era of neoadjuvant treatment, the implications of lymph node yield and status on patient outcomes remains unclear. PATIENT AND METHODS: This study included 1,680 patients with locally advanced rectal cancer from the NCCN prospective oncology database stratified into 3 groups based on preoperative therapy received: no neoadjuvant therapy, neoadjuvant chemoradiation, and neoadjuvant chemotherapy...
December 2016: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/27951611/clinical-implications-of-low-grade-dysplasia-found-during-inflammatory-bowel-disease-surveillance-a-retrospective-study-comparing-chromoendoscopy-and-white-light-endoscopy
#9
Joren R Ten Hove, Erik Mooiweer, Andrea E van der Meulen de Jong, Evelien Dekker, Cyriel Y Ponsioen, Peter D Siersema, Bas Oldenburg
Background and study aims: Current guidelines recommend the use of pancolonic chromoendoscopy for surveillance of patients with inflammatory bowel disease (IBD). It is currently unknown whether low grade dysplasia (LGD) found using chromoendoscopy carries a similar risk of high grade dysplasia (HGD) or colorectal cancer (CRC) compared with LGD detected using white-light endoscopy (WLE). The aim of this study was to compare the risk of advanced neoplasia, a combined endpoint of HGD and CRC, during follow-up after detection of lesions containing LGD identified with either chromoendoscopy or WLE...
December 12, 2016: Endoscopy
https://www.readbyqxmd.com/read/27942902/impact-of-proximal-vascular-ligation-on-survival-of-patients-with-colon-cancer
#10
Ian M Paquette, Robert D Madoff, Elin R Sigurdson, George J Chang
In an effort to optimize further the surgical management of colon cancer, many groups have advocated extended lymphadenectomy as a strategy to improve completeness of resection and lymph node harvest. This review evaluates lymphadenectomy according to the definitions for extent of lymph node dissection based on the guidelines provided by the Japanese Society of Cancer of the Colon and Rectum and the contemporary concepts of complete mesocolic excision and central vascular ligation. The proposed benefits of a D3 or central nodal dissection along root vessels in colon cancer is improving accuracy of lymph node evaluation and ensuring complete removal of lymph nodes that may harbor undetected tumor cells or other undefined immunologic processes important for metastases...
December 9, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27941344/routine-colonoscopy-after-acute-uncomplicated-diverticulitis-challenging-a-putative-indication
#11
Patrícia Andrade, Armando Ribeiro, Rosa Ramalho, Susana Lopes, Guilherme Macedo
BACKGROUND AND AIMS: Most international guidelines recommend performing a routine colonoscopy after the conservative management of acute diverticulitis, mainly to rule out a colorectal malignancy; however, data to support these recommendations are scarce and conflicting. This study is aimed at determining the rate of advanced colonic neoplasia (ACN) found by colonoscopy, and hence the need for routine colonoscopy after CT-diagnosed acute diverticulitis. METHODS: We retrospectively analyzed all patients hospitalized for acute diverticulitis between July 2008 and June 2013...
December 10, 2016: Digestive Surgery
https://www.readbyqxmd.com/read/27927666/epigenetic-biomarkers-in-progression-from-non-dysplastic-barrett-s-oesophagus-to-oesophageal-adenocarcinoma-a-systematic-review-protocol
#12
T Nieto, C L Tomlinson, J Dretzke, S Bayliss, M Dilworth, A D Beggs, O Tucker
INTRODUCTION: Barrett's oesophagus (BO), a metaplastic condition affecting the lower oesophagus due to long-standing gastro-oesophageal reflux and chronic inflammation, is a precursor lesion for oesophageal adenocarcinoma (OADC). There is no clinical test to predict which patients with BO will progress to OADC. The British Society of Gastroenterology recommends endoscopic surveillance of patients with BO. Epigenetic changes have been well characterised in the neoplastic progression of ulcerative colitis to colonic carcinoma, another gastrointestinal cancer associated with chronic inflammation...
December 7, 2016: BMJ Open
https://www.readbyqxmd.com/read/27926553/omission-of-adjuvant-chemotherapy-is-associated-with-increased-mortality-in-patients-with-t3n0-colon-cancer-with-inadequate-lymph-node-harvest
#13
Katerina O Wells, Alexander T Hawkins, Devi M Krishnamurthy, Sekhar Dharmarajan, Sean C Glasgow, Steven R Hunt, Matthew G Mutch, Paul Wise, Matthew L Silviera
BACKGROUND: Adjuvant chemotherapy for T3N0 colon cancer is controversial. National guidelines recommend its use in patients with stage II with high-risk features, including lymph node harvest of less than 12, yet this treatment is underused. OBJECTIVE: The purpose of this study was to demonstrate that the use of adjuvant chemotherapy in patients with T3N0 adenocarcinoma with inadequate lymph node harvest is beneficial. DESIGN: This was a retrospective population-based study of patients with resected T3N0 adenocarcinoma of the colon...
January 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/27926551/the-role-of-surgeons-and-oncologists-combined-to-properly-apply-colon-cancer-guidelines
#14
Luca Stocchi
No abstract text is available yet for this article.
January 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/27889874/decision-support-provided-by-a-temporally-oriented-health-care-assistant-an-implementation-of-computer-interpretable-guidelines
#15
Tiago Oliveira, António Silva, José Neves, Paulo Novais
The automatic interpretation of clinical recommendations is a difficult task, even more so when it involves the processing of complex temporal constraints. In order to address this issue, a web-based system is presented herein. Its underlying model provides a comprehensive representation of temporal constraints in Clinical Practice Guidelines. The expressiveness and range of the model are shown through a case study featuring a Clinical Practice Guideline for the diagnosis and management of colon cancer. The proposed model was sufficient to represent the temporal constraints in the guideline, especially those that defined periodic events and placed temporal constraints on the assessment of patient states...
January 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/27889548/impact-of-physician-compliance-with-colonoscopy-surveillance-guidelines-on-interval-colorectal-cancer
#16
Jennifer Nayor, John R Saltzman, Emily J Campbell, Molly L Perencevich, Kunal Jajoo, James M Richter
BACKGROUND AND AIMS: Interval colorectal cancer (iCRC) incidence is the criterion standard benchmark for measuring the effectiveness of colonoscopy. Colonoscopy surveillance guidelines are designed to minimize iCRC cases. Our aims were to describe characteristics of iCRC patients and to assess whether development of iCRC is related to colonoscopy surveillance guideline intervals. METHODS: We performed a retrospective cohort study of postcolonoscopy iCRC cases in a large healthcare system...
November 24, 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27884517/endoscopic-morphologic-features-of-ulcerative-colitis-associated-dysplasia-classified-according-to%C3%A2-the%C3%A2-scenic%C3%A2-consensus-statement
#17
Shinya Sugimoto, Makoto Naganuma, Yasushi Iwao, Katsuyoshi Matsuoka, Masayuki Shimoda, Shuji Mikami, Shinta Mizuno, Yoshihiro Nakazato, Kosaku Nanki, Nagamu Inoue, Haruhiko Ogata, Takanori Kanai
BACKGROUND AND AIMS: Recent advances in endoscopic equipment and diagnostic techniques have made possible the detection of early dysplasia in the inflamed mucosa of ulcerative colitis (UC). The SCENIC consensus statement recommends the use of unified terminology for the morphology of dysplasia. In this study, we investigated the endoscopic features of high-grade dysplasia (HGD) in a clinical setting. METHODS: We retrospectively identified 62 patients with UC who were diagnosed with colitis-associated cancer or HGD between 1997 and 2015...
November 21, 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27864808/latina-and-black-african-american-women-s-perspectives-on-cancer-screening-and-cancer-screening-reminders
#18
Susan Brandzel, Eva Chang, Leah Tuzzio, Camille Campbell, Nora Coronado, Erin J Aiello Bowles, Susan Carol Bradford, Diana S M Buist
INTRODUCTION: Racial and ethnic disparities continue to exist in cancer screening rates, especially among US Latina and Black/African American populations. We conducted six focus groups among 41 women from these communities in order to better understand their preferences about cancer screening reminders and the motivators and deterrents they face in obtaining recommended breast, cervical, and colon cancer screening. METHODS: Using self-reported patient race/ethnicity from electronic medical records of a large, integrated health care system in Seattle, we recruited women ages 30-60 to participate in one of five 2-hour focus groups...
November 18, 2016: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/27856106/surgical-management-of-colorectal-cancer-for-the-aging-population-a-survey-by-the-japanese-society-for-cancer-of-colon-and-rectum
#19
Hiroshi Matsuoka, Kotaro Maeda, Tsunekazu Hanai, Harunobu Sato, Koji Masumori, Yosikazu Koide, Hidetoshi Katsuno, Tomoyoshi Endo, Miho Shiota, Kenichi Sugihara
OBJECTIVE: The treatment policy of colorectal cancer in elderly patients is controversial due to a lack of specific guidelines. To clarify the present management of colorectal cancer for aged patients, a questionnaire survey was conducted by the Japanese Society for Cancer of the Colon and Rectum. METHODS: Questionnaire forms were sent to the 430 member institutions of the Japanese Society for Cancer of the Colon and Rectum. RESULTS: The response rate of the surgical department to the questionnaire was 39%...
November 14, 2016: Asian Journal of Surgery
https://www.readbyqxmd.com/read/27846172/colon-cancer-surgery-a-retrospective-study-based-on-a-large-administrative-database
#20
Mario Saia, Alessandra Buja, Domenico Mantoan, Ferdinando Agresta, Vincenzo Baldo
INTRODUCTION: Laparoscopic colectomy (LC) for colon cancer is considered as safe and effective as open colectomy. It has many benefits in terms of postoperative pain, length of hospital stay, and esthetic results. There is evidence in the United States of a positive trend in the proportion of oncologic patients undergoing LC. Our aim is to confirm this trend in Europe and identify factors associated with a greater use of LC. MATERIALS AND METHODS: A retrospective cohort study based on hospital discharge records (HDR) collected from 2008 to 2013 in a north-eastern Italian region (Veneto)...
December 2016: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
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