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https://www.readbyqxmd.com/read/29422252/achieving-high-quality-standards-in-laparoscopic-colon-resection-for-cancer-a-delphi-consensus-based-position-paper
#1
Laura Lorenzon, Alberto Biondi, Thomas Carus, Adam Dziki, Eloy Espin, Nuno Figueiredo, Marcos Gomez Ruiz, Tamas Mersich, Isacco Montroni, Pieter J Tanis, Stefan Rolf Benz, Paolo Pietro Bianchi, Matthias Biebl, Ivo Broeders, Raffaele De Luca, Paolo Delrio, Mathieu D'Hondt, Alois Fürst, Jan Grosek, Jose Flavio Guimaraes Videira, Friedrich Herbst, David Jayne, György Lázár, Danilo Miskovic, Andrea Muratore, Ole Helmer Sjo, Tom Scheinin, Ales Tomazic, Andreas Türler, Cornelius Van de Velde, Steven D Wexner, Christoph Wullstein, Wojciech Zegarski, Domenico D'Ugo
AIM: To investigate the rate of laparoscopic colectomies for colon cancer using registries and population-based studies. To provide a position paper on mini-invasive (MIS) colon cancer surgery based on the opinion of experts leader in this field. METHODS: A systematic review of the literature was conducted using PRISMA guidelines for the rate of laparoscopy in colon cancer. Moreover, Delphi methodology was used to reach consensus among 35 international experts in four study rounds...
February 5, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29415287/residual-adenoma-after-cold-snare-polypectomy-for-small-colorectal-adenomas-a-prospective-clinical-study
#2
Daisuke Maruoka, Makoto Arai, Naoki Akizue, Kentaro Ishikawa, Shingo Kasamatsu, Takashi Taida, Hideaki Ishigami, Kenichiro Okimoto, Keiko Saito, Tomoaki Matsumura, Tomoo Nakagawa, Tatsuro Katsuno, Naoya Kato
BACKGROUND: Endoscopic resection of all colonic adenomas prevents the occurrence of colon cancer and death. The European Society of Gastrointestinal Endoscopy Clinical Guideline recommends resection of all polyps predicted to be adenomas and cold snare polypectomy (CSP) for removal of adenomas ≤ 9 mm on the basis of safety; however, it also states that this recommendation lacks adequate evidence of efficacy. The residual adenoma rate after resection is an important indicator of efficacy, but there have been no reports showing this prospectively...
February 7, 2018: Endoscopy
https://www.readbyqxmd.com/read/29401168/long-term-outcomes-of-gastroenteropancreatic-neuroendocrine-tumors
#3
Weiwei Chi, Richard R P Warner, David L Chan, Simron Singh, Eva Segelov, Jonathan Strosberg, Juan Wisnivesky, Michelle K Kim
OBJECTIVES: Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are rare but have been increasing in incidence. Limited data on the long-term outcomes of patients with these tumors are available. METHODS: In this study, we used population-based data from the National Cancer Institute to assess long-term disease-specific survival (DSS) of patients who have undergone surgery for nonmetastatic disease. All patients with NETs of the stomach, small intestine, colon, rectum, appendix, and pancreas diagnosed between 1988 and 2009 were identified from the Surveillance, Epidemiology and End Results registry...
February 2, 2018: Pancreas
https://www.readbyqxmd.com/read/29394758/-long-term-survival-of-a-patient-with-metastatic-liver-and-para-aortic-lymph-node-cancer-from-colon-cancer-treated-with-regorafenib
#4
Nobuyuki Watanabe, Shigenori Akagi, Hiroyuki Inoue, Hiroki Nakatsuji, Hiroshi Ito, Atsushi Toma, Kenji Nakamura, Toshiya Ochiai, Eigo Otsuji
A 54-year-old man was presented at our hospital with weight loss.He diagnosed with colorectal cancer, multiple liver metastases and para-aortic lymph node metastasis.After undergoing colostomy, he was treated sequentially with mFOLFOX6 plus bevacizumab(Bmab), FOLFIRI plus Bmab or Pmab, according to the guideline.Since these chemotherapy resulted in progressive disease, regorafenib was administered as a salvage-line treatment.PET -CT showed only para-aortic lymph node swelling with high FDG uptake.Severe adverse effects were developed shortly after regorafenib treatment so he requireda reduction in dose...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394750/-examination-of-cases-of-hepatectomy-for-metastatic-colorectal-cancer
#5
Shinichiro Chino, Masanori Naito, Takeshi Kaida, Hideki Ushiku, Wataru Yamashita, Hidefumi Kubo, Yasushi Kondo, Yatsushi Nishi, Yoshihito Takahashi, Masahiko Watanabe
OBJECTIVES: Resection of liver metastasis from colorectal cancer is known to improve prognosis; therefore, surgical treatment is recommended for resectable metastases in the Japanese Society for Cancer of the Colon and Rectum Guidelines for the Treatment of Colorectal Cancer. In this study, we investigated factors that affect the prognosis of resection of such metastatic liver tumors. RESULTS: Thirty-three cases of liver resection performed during the period from 1998 to 2017 were investigated...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29385427/diagnostic-yield-of-dysplasia-in-polyp-adjacent-biopsies-for-patients-with-inflammatory-bowel-disease-a-cross-sectional-study
#6
Conor Lahiff, Lai Mun Wang, Simon P L Travis, James E East
Introduction: Patients with inflammatory bowel disease (IBD) undergoing polypectomy are recommended by current guidelines to have biopsies taken from adjacent mucosa to determine whether there is dysplasia present. With improvements in endoscopic imaging it is now possible to characterise colonic lesions with higher levels of confidence than previously. We reviewed the diagnostic yield of polyp-adjacent biopsies in IBD. Materials and Methods: A systematic search of our histopathology database revealed cases where polyps had been endoscopically resected or biopsied in patients with IBD...
January 27, 2018: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/29381999/abdominal-surgery-in-patients-with-essential-thrombocythemia-a-case-report-and-systematic-review-of-literature
#7
Yi Zhu, HongGang Jiang, ZhiHeng Chen, BoHao Lu, JiaMing Wu
INTRODUCTION: Essential thrombocythemia/thrombocytosis (ET) is characterized by increased bleeding and thrombosis risk during the perioperative period. We report the case of a woman with ET and sigmoid colon cancer, in whom the postoperative course was complicated by anastomotic bleeding. A systematic review was conducted to seek guidance for the management of such patient in the perioperative period. METHODS: A systematic literature review was conducted using EMBASE, Medline, and PubMed databases to detect relevant English language articles...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29354876/evaluating-treatment-patterns-for-small-cell-carcinoma-of-the-colon-using-the-national-cancer-database-ncdb
#8
Sadhana Balasubramanyam, Barrett P O'Donnell, Benjamin L Musher, Pavan M Jhaveri, Michelle S Ludwig
OBJECTIVE(S): The objective of this study was to characterize the clinicopathological prognostic factors and treatment patterns for small cell carcinoma (SCC) of the colon, a rare disease without standard treatment guidelines. METHODS: We analyzed clinicopathological and treatment variables for 503 cases of histologically proven SCC colon entered into the National Cancer Database (NCDB) between 2004 and 2013. Survival curves were generated using Kaplan-Meier and compared by the log-rank test...
January 22, 2018: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/29353416/physicians-decision-about-long-term-thromboprophylaxis-in-cancer-outpatients-cat-axis-a-case-vignette-study-on-clinical-practice-in-france
#9
Florian Scotté, I Elalamy, D Mayeur, G Meyer
PURPOSE: Data on long-term venous thromboembolism prophylaxis in cancer outpatients remain scarce. In the absence of clear and consistent treatment guidelines, our objectives were to describe and better understand clinical practice and to identify factors influencing the use of thromboprophylaxis. METHODS: CAT AXIS was a multicentred cross-sectional study based on the completion of physician-profile questionnaires and the assessment of 10 e-mailed credible clinical scenarios of lung, colon and breast cancers by each of participants using the case vignette-validated method...
January 20, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29352814/does-adherence-to-the-world-cancer-research-fund-american-institute-of-cancer-research-cancer-prevention-guidelines-reduce-risk-of-colorectal-cancer-in-the-uk-women-s-cohort-study
#10
Petra Jones, Janet E Cade, Charlotte E L Evans, Neil Hancock, Darren C Greenwood
Evidence on adherence to diet-related cancer prevention guidelines and associations with colorectal cancer (CRC) risk is limited and conflicting. The aim of this cohort analysis is to evaluate associations between adherence to the World Cancer Research Fund/American Institute of Cancer Research (WCRF/AICR) 2007 recommendations and incident CRC. The UK Women's Cohort Study comprises over 35 372 women who filled in a FFQ at baseline in 1995. They were followed up for CRC incidence for a median of 17·4 years, an individual score linking adherence to eight of the WCRF/AICR recommendations was constructed...
January 21, 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29337781/comparison-of-western-and-asian-guidelines-concerning-the-management-of-colon-cancer
#11
Gianluca Pellino, Oliver Warren, Sarah Mills, Shahnawaz Rasheed, Paris P Tekkis, Christos Kontovounisios
BACKGROUND: Guidelines are important to standardize treatments and optimize outcomes. Several societies have published authoritative guidelines for patients with colon cancer, and a certain degree of variation can be predicted. OBJECTIVE: This study aims to compare Western and Asian guidelines for the management of colon cancer. DATA SOURCES: A literature review was performed following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for studies published between 2010 and 2017 by the online resources from the official Web sites of the societies/panels...
February 2018: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/29334918/colorectal-cancer-liver-metastases-a-population-based-study-on-incidence-management-and-survival
#12
Jennie Engstrand, Henrik Nilsson, Cecilia Strömberg, Eduard Jonas, Jacob Freedman
BACKGROUND: Colorectal cancer (CRC) is a leading cause of cancer-associated deaths with liver metastases developing in 25-30% of those affected. Previous data suggest a survival difference between right- and left-sided liver metastatic CRC, even though left-sided cancer has a higher incidence of liver metastases. The aim of the study was to describe the liver metastatic patterns and survival as a function of the characteristics of the primary tumour and different combinations of metastatic disease...
January 15, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29319900/laypersons-knowledge-and-perceptions-of-irritable-bowel-syndrome-as-potential-barriers-to-care
#13
LeeAnne B Sherwin
AIMS: To describe the layperson's knowledge and perceptions regarding the aetiology, pathogenesis, prevalence, medical evaluation, diagnosis and treatment of Irritable Bowel Syndrome. BACKGROUND: Diagnosis acceptance and adherence to treatment is influenced by the views of the patient's social networks. Little is known how these networks influence those with Irritable Bowel Syndrome. DESIGN: Cross-sectional study of two-hundred four laypersons, ages 18-80 years without an Irritable Bowel Syndrome diagnosis...
January 10, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29310582/identification-of-uncommon-oral-yeasts-from-cancer-patients-by-maldi-tof-mass-spectrometry
#14
Narges Aslani, Ghasem Janbabaei, Mahdi Abastabar, Jacques F Meis, Mahasti Babaeian, Sadegh Khodavaisy, Teun Boekhout, Hamid Badali
BACKGROUND: Opportunistic infections due to Candida species occur frequently in cancer patients because of their inherent immunosuppression. The aim of the present study was to investigate the epidemiology of yeast species from the oral cavity of patients during treatment for oncological and haematological malignancies. METHODS: MALDI-TOF was performed to identify yeasts isolated from the oral cavity of 350 cancer patients. Moreover, antifungal susceptibility testing was performed in according to CLSI guidelines (M27-A3)...
January 8, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29289528/cystic-fibrosis-colorectal-cancer-screening-consensus-recommendations
#15
Denis Hadjiliadis, Alexander Khoruts, Ann G Zauber, Sarah E Hempstead, Patrick Maisonneuve, Albert B Lowenfels
BACKGROUND & AIMS: Improved therapy has substantially increased survival of persons with cystic fibrosis (CF). But the risk of colorectal cancer (CRC) in adults with CF is 5-10 times greater compared to the general population, and 25-30 times greater in CF patients after an organ transplantation. To address this risk, the CF Foundation convened a multi-stakeholder task force to develop CRC screening recommendations. METHODS: The 18-member task force consisted of experts including pulmonologists, gastroenterologists, a social worker, nurse coordinator, surgeon, epidemiologist, statistician, CF adult, and a parent...
December 28, 2017: Gastroenterology
https://www.readbyqxmd.com/read/29243502/evidence-based-management-of-incidental-focal-uptake-of-fluorodeoxyglucose-on-pet-ct
#16
Deborah Pencharz, Malavika Nathan, Thomas L Wagner
Focal incidental uptake, with or without CT abnormalities, is a common finding on FDG PET/CT and evidence based management for this type of uptake is lacking. This article reviews the evidence on focal incidental uptake including the incidence of malignancy, differential diagnosis and imaging criteria which can be used to further characterise it. The article focusses on PET rather than CT criteria. The strength of the evidence base is highly variable ranging from systematic reviews and meta-analyses to a virtual absence of evidence...
December 15, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/29237405/prevalence-and-characteristics-of-hereditary-non-polyposis-colorectal-cancer-hnpcc-syndrome-in-immigrant-asian-colorectal-cancer-patients
#17
Jasmine Lee, Yin-Yi Xiao, Yan Yu Sun, Jasminka Balderacchi, Bradley Clark, Jatin Desani, Vivek Kumar, Angela Saverimuthu, Khin Than Win, Yiwu Huang, Yiqing Xu
BACKGROUND: The prevalence of Hereditary Non-Polyposis Colorectal Cancer (HNPCC) is 2 to 5% in the Caucasian population. HNPCC is caused by genomic mutations in DNA mismatch repair genes (MMR), namely MLH1, MSH2, MSH6, PMS2, and EPCAM. A non-hereditary, acquired process of hypermethylation of the MLH1 promoter can also lead to silencing of MLH1 protein expression. Diagnosis of HNPCC in patients with colorectal and other related cancers is important in the clinical treatment and surveillance of related cancers...
December 13, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29228759/combination-of-primary-tumor-location-and-mismatch-repair-status-guides-adjuvant-chemotherapy-in-stage-ii-colon-cancer
#18
Lin Yang, Wenzhuo He, Qiong Yang, Pengfei Kong, Qiankun Xie, Chang Jiang, Bei Zhang, Liang Ping Xia
Background: Current opinions on the benefits of adjuvant chemotherapy for stage II colon cancer are divided and reformative election of these patients is required. We examined whether the primary tumor location based on mismatch repair status and other risk factors could better inform the current guideline. Materials and Methods: A total of 673 consecutive patients with stage II colon cancer were included in the analysis. Differences in the common clinicopathological factors between left-sided colon cancer and right-sided colon cancer were analyzed using Fisher's exact analysis...
November 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29220062/community-academic-partnership-to-implement-a-breast-and-cervical-cancer-screening-education-program-in-puerto-rico
#19
Vivian Colón-López, Daisy González, Camille Vélez, Natalie Fernández-Espada, Alana Feldman-Soler, Kelly Ayala-Escobar, Alelí M Ayala-Marín, Marievelisse Soto-Salgado, William A Calo, Angela Pattatucci-Aragón, Marinilda Rivera-Díaz, María E Fernández
OBJECTIVE: To describe how a community-academic partnership between Taller Salud Inc., a community-based organization, and the Puerto Rico Community Cancer Control Outreach Program of the University of Puerto Rico was crucial in the adaptation and implementation of Cultivando La Salud (CLS), an evidencebased educational outreach program designed to increase breast and cervical cancer screening among Hispanic women living in Puerto Rico. This collaboration facilitated the review and adaptation of the CLS intervention to improve cultural appropriateness, relevance, and acceptability for Puerto Rican women...
December 2017: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/29207857/diagnosis-and-management-of-rectal-neuroendocrine-tumors
#20
REVIEW
Shreya Chablaney, Zachary A Zator, Nikhil A Kumta
The incidence of rectal neuroendocrine tumors (NETs) has increased by almost ten-fold over the past 30 years. There has been a heightened awareness of the malignant potential of rectal NETs. Fortunately, many rectal NETs are discovered at earlier stages due to colon cancer screening programs. Endoscopic ultrasound is useful in assessing both residual tumor burden after retrospective diagnosis and tumor characteristics to help guide subsequent management. Current guidelines suggest endoscopic resection of rectal NETs ≤10 mm as a safe therapeutic option given their low risk of metastasis...
November 2017: Clinical Endoscopy
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