I Latorzeff, G Ploussard, J Guillotreau, F Jonca, P Labarthe, G Rollin, J-B Beauval, A Pathak
Prostate cancer, the most frequent cancer in man, is an adenocarcinoma sensible to chemical castration in more than 80% of cases due to its hormonal dependency. Androgen deprivation is the treatment for advanced cancer and can be associated with radiotherapy locally or in locally advanced situations. Multidisciplinary therapeutic choice depends on patient age and co-morbidities and clinical stage. The impact of hormonal treatment confers varied side effects and cardiovascular effects are now better known. Responsible mechanisms of this cardiotoxicity are at the same time direct but also indirect by metabolic thermogenic effects...
July 2016: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique