keyword
MENU ▼
Read by QxMD icon Read
search

the balanced study

keyword
https://www.readbyqxmd.com/read/29031155/the-effect-of-nanoparticle-aggregation-on-surfactant-foam-stability
#1
Zuhair A AlYousef, Mohammed A Almobarky, David S Schechter
The combination of nanoparticles (NPs) and surfactant may offer a novel technique of generating stronger foams for gas mobility control. This study evaluates the potential of silica NPs to enhance the foam stability of three nonionic surfactants. Results showed that the concentration of surfactant and NPs is a crucial parameter for foam stability and that there is certain concentrations for strong foam generation. A balance in concentration between the nonionic surfactants and the NPs can enhance the foam stability as a result of forming flocs in solutions...
September 20, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29031081/optimization-of-the-promega-powerseq%C3%A2-auto-y-system-for-efficient-integration-within-a-forensic-dna-laboratory
#2
E A Montano, J M Bush, A M Garver, M M Larijani, S M Wiechman, C H Baker, M R Wilson, R A Guerrieri, E A Benzinger, D N Gehres, M L Dickens
The application of massively parallel sequencing (MPS) is growing in the forensic DNA field, as forensic DNA laboratories are continuously seeking methods to gain information from a limited or degraded forensic sample. However, the laborious nature of current MPS methodologies required for successful library preparation and sequencing leave opportunities for improvement to make MPS a practical option for processing forensic casework. In this study, the Promega PowerSeq™ Auto/Y System Prototype, a MPS laboratory workflow that incorporates multiplex amplification, was selected for optimization with the objectives to introduce automation for relieving manual processing, and to reduce the number of steps recommended by the standard protocol...
October 5, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/29029240/a-greater-extent-of-insomnia-symptoms-and-physician-recommended-sleep-medication-use-predict-fall-risk-in-community-dwelling-older-adults
#3
Tuo-Yu Chen, Soomi Lee, Orfeu M Buxton
Study Objectives: Cross-sectional studies suggest that insomnia symptoms are associated with falls in later life. This longitudinal study examines the independent and interactive effects of the extent of insomnia symptoms (i.e., multiple co-existing insomnia symptoms) and sleep medications on fall risk over a 2-year follow-up among community-dwelling older adults. Methods: Using data from the Health and Retirement Study (2006-2014, N = 6882, Mage = 74.5 years ± 6...
October 3, 2017: Sleep
https://www.readbyqxmd.com/read/29029102/nucleos-t-ide-analogue-treatment-for-adult-patients-with-hbeag-positive-chronic-infection-with-genotype-c-hepatitis-b-virus-a-nationwide-real-life-study
#4
Young Chang, Won Hyeok Choe, Dong Hyun Sinn, Jeong-Hoon Lee, Sang Hoon Ahn, Hyewon Lee, Jae-Jun Shim, Dae Won Jun, Soo Young Park, Joon Yeul Nam, Eun Ju Cho, Su Jong Yu, Dong Ho Lee, Jeong Min Lee, Yoon Jun Kim, So Young Kwon, Seung Woon Paik, Jung-Hwan Yoon
Background/Aim: Antiviral treatment for patients in HBeAg-positive chronic hepatitis B virus (HBV) infection is still controversial. We assessed whether antiviral treatment reduces liver disease progression in those patients. Methods: This study included consecutive patients that tested positive for HBeAg with an HBV DNA >20,000 IU/mL, ALT <40 IU/L and without evidence of cirrhosis in eight large-volume hospitals in Korea. The primary endpoint was the development of hepatocellular carcinoma (HCC) and the secondary endpoint was the development of cirrhosis...
September 23, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29029078/prebiotic-potential-of-pectin-and-pectic-oligosaccharides-to-promote-anti-inflammatory-commensal-bacteria-in-the-human-colon
#5
Wing Sun Faith Chung, Marjolein Meijerink, Birgitte Zeuner, Jesper Holck, Petra Louis, Anne Meyer, Jerry M Wells, Harry J Flint, Sylvia H Duncan
Dietary plant cell wall carbohydrates are important in modulating the composition and metabolism of the complex gut microbiota, which can impact on health. Pectin is a major component of plant cell walls. Based on studies in model systems and available bacterial isolates and genomes, the capacity to utilize pectins for growth is widespread among colonic Bacteroidetes but relatively uncommon among Firmicutes. One Firmicutes species promoted by pectin is Eubacterium eligens. E. eligens DSM3376 utilizes apple pectin and encodes a broad repertoire of pectinolytic enzymes, including a highly abundant pectate lyase of around 200 kDa that is expressed constitutively...
October 3, 2017: FEMS Microbiology Ecology
https://www.readbyqxmd.com/read/29028771/mechanisms-of-thrombocytopenia-during-septic-shock-a-multiplex-cluster-analysis-of-endogenous-sepsis-mediators
#6
Alexandre Bedet, Keyvan Razazi, Florence Boissier, Mathieu Surenaud, Sophie Hue, Stéphane Giraudier, Christian Brun-Buisson, Armand Mekontso Dessap
BACKGROUND: Thrombocytopenia is a common feature of sepsis and may involve various mechanisms often related to the inflammatory response. This study aimed at evaluating factors associated with thrombocytopenia during human septic shock. In particular, we used a multiplex analysis to assess the role of endogenous sepsis mediators. METHODS: Prospective, observational study. Thrombocytopenia was defined as an absolute platelet count <100 G/L or a 50% relative decrease in platelet count during the first week of septic shock...
October 12, 2017: Shock
https://www.readbyqxmd.com/read/29028763/effects-of-hyperoxia-during-resuscitation-from-hemorrhagic-shock-in-swine-with-preexisting-coronary-artery-disease
#7
Clair Hartmann, Maurizio Loconte, Elena Antonucci, Michael Holzhauser, Tobias Hölle, David Katzsch, Tamara Merz, Oscar McCook, Ulrich Wachter, Josef A Vogt, Andrea Hoffmann, Martin Wepler, Michael Gröger, Martin Matejovic, Enrico Calzia, Michael Georgieff, Pierre Asfar, Peter Radermacher, Benedikt L Nussbaum
OBJECTIVES: Investigation of the effects of hyperoxia during resuscitation from hemorrhagic shock in swine with preexisting coronary artery disease. DESIGN: Prospective, controlled, randomized trial. SETTING: University animal research laboratory. SUBJECTS: Nineteen hypercholesterolemic pigs with preexisting coronary artery disease. INTERVENTIONS: Anesthetized, mechanically ventilated, and surgically instrumented pigs underwent 3 hours of hemorrhagic shock (removal of 30% of the calculated blood volume and subsequent titration of mean arterial blood pressure ≈40 mm Hg)...
October 12, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/29028741/fundamental-epidemiology-terminology-and-measures-it-really-is-all-in-the-name
#8
Thomas R Vetter, Christine A Jesser
Epidemiology is the study of how disease is distributed in populations and the factors that influence or determine this distribution. Clinical epidemiology denotes the application of epidemiologic methods to questions relevant to patient care and provides a highly useful set of principles and methods for the design and conduct of quantitative clinical research. Validly analyzing, correctly reporting, and successfully interpreting the findings of a clinical research study often require an understanding of the epidemiologic terms and measures that describe the patterns of association between the exposure of interest (treatment or intervention) and a health outcome (disease)...
October 11, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29028627/local-dynamic-stability-during-treadmill-walking-can-detect-children-with-developmental-coordination-disorder
#9
Merete B Speedtsberg, Sofie B Christensen, Jan Stenum, Thomas Kallemose, Jesper Bencke, Derek J Curtis, Bente R Jensen
OBJECTIVE: Developmental coordination disorder (DCD) is an innate impairment of motor coordination that affects basic locomotion and balance. This study investigated local dynamic stability of trunk accelerations during treadmill walking as an objective evaluation of gait stability and the sensitivity and specificity of this measure to discriminate children with DCD from typically developing children. METHOD: Eight children with DCD and ten age- and gender-matched typically developing children (TD) walked four minutes on a treadmill...
October 5, 2017: Gait & Posture
https://www.readbyqxmd.com/read/29028622/virtual-reality-balance-training-for-elderly-similar-skiing-games-elicit-different-challenges-in-balance-training
#10
Aijse W de Vries, Gert Faber, Ilse Jonkers, Jaap H Van Dieen, Sabine M P Verschueren
BACKGROUND: Virtual Reality (VR) balance training may have advantages over regular exercise training in older adults. However, results so far are conflicting potentially due to the lack of challenge imposed by the movements in those games. Therefore, the aim of this study was to assess to which extent two similar skiing games challenge balance, as reflected in center of mass (COM) movements relative to their Functional Limits of Stability (FLOS). METHODS: Thirty young and elderly participants performed two skiing games, one on the Wii Balance board (Wiiski), which uses a force plate, and one with the Kinect sensor (Kinski), which performs motion tracking...
October 5, 2017: Gait & Posture
https://www.readbyqxmd.com/read/29028541/tuning-the-structure-of-aminoferrocene-based-anticancer-prodrugs-to-prevent-their-aggregation-in-aqueous-solution
#11
Steffen Daum, Svetlana Babiy, Helen Konovalova, Walter Hofer, Alexander Shtemenko, Natalia Shtemenko, Christina Janko, Christoph Alexiou, Andriy Mokhir
Aminoferrocene-based prodrugs are activated in cancer cells by reactive oxygen species (ROS). They were shown to exhibit high cytotoxicity towards a variety of cancer cell lines and primary cancer cells, but remain not toxic towards non-malignant cells. However, these prodrugs have rather high lipophilicity leading to relatively low water solubility. In particular, an n-octanol/water partition coefficient for the best aminoferrocene-based prodrug (2) was found to be 4.51±0.03. Though the approaches for decreasing lipophilicity are straightforward and include the addition of polar residues to the drug structure, these modifications also lead to dramatic decrease of cell permeability and, correspondingly, lower the activity of the drug...
September 15, 2017: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/29028506/sodium-deoxycholate-mediated-enhanced-solubilization-and-stability-of-hydrophobic-drug-clozapine-in-pluronic-micelles
#12
Pankaj Singla, Onkar Singh, Shruti Chabba, V K Aswal, Rakesh Kumar Mahajan
In this report, the solubilization behaviour of a hydrophobic drug Clozapine (CLZ) in micellar suspensions of pluronics having different hydrophilic lipophilic balance (HLB) ratios viz. P84, F127 and F108 in the absence and presence of bile salt sodium deoxycholate (SDC) has been studied. UV-Vis spectroscopy has been exploited to determine the solubilization capacity of the investigated micellar systems in terms of drug loading efficiency, average number of drug molecules solubilized per micelle (ns), partition coefficient (P) and standard free energy of solubilization (∆G(°))...
October 7, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/29028315/nanoparticles-of-short-cationic-peptidopolysaccharide-self-assembled-by-hydrogen-bonding-with-antibacterial-effect-against-multi-drug-resistant-bacteria
#13
Zheng Hou, Yogesh Vikhe Shankar, Yang Liu, Feiqing Ding, Jothy Lachumy Subramanion, Vikashini Ravikumar, Rubí Zamudio-Vázquez, Damien Keogh, Huiwen Lim, Moon Yue Feng Tay, Surajit Bhattacharjya, Scott A Rice, Jian Shi, Hongwei Duan, Xue-Wei Liu, Yuguang Mu, Nguan Soon Tan, Kam Michael Chiu Tam, Kevin Pethe, Mary B Chan-Park
Cationic antimicrobial peptides (AMPs) and polymers are active against many multi-drug resistant (MDR) bacteria but only a limited number of these compounds are in clinical use due to their unselective toxicity. The typical strategy for achieving selective antibacterial efficacy with low mammalian cell toxicity is through balancing the ratio of cationicity to hydrophobicity. Herein, we report a cationic nanoparticle self-assembled from chitosan-graft-oligolysine (CSM5-K5) chains with ultra-low molecular weight (1450 Daltons) that selectively kills bacteria...
October 13, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29027777/immobilisation-during-anaesthesia-for-vitrectomy-using-a-laryngeal-mask-without-neuromuscular-blockade-versus-endotracheal-intubation-and-neuromuscular-blockade
#14
Axel Fudickar, Matthias Gruenewald, Beate Fudickar, Moritz Hill, Martin Wallenfang, Julia Hüllemann, Dana Voss, Amke Caliebe, Johann B Roider, Markus Steinfath, Felix Treumer
BACKGROUND: For intraocular surgery, most authors recommend general anaesthesia including intubation and neuromuscular blockade to avoid complications by patient movements. However, anaesthesia using a laryngeal mask and avoidance of muscle relaxants is common clinical practice. Purpose of this prospective observational study was to compare the incidence of eye movement and deviation of the eye axis during general anaesthesia adjusted to minimal alveolar concentration (MAC) for pars plana-vitrectomy (PPV) using a laryngeal mask without neuromuscular blockade (LM) versus endotracheal intubation and neuromuscular blockade (INT)...
October 12, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/29027705/effects-of-dietary-supplementation-of-spices-on-forage-degradability-ruminal-fermentation-in-vivo-digestibility-growth-performance-and-nitrogen-balance-in-black-bengal-goat
#15
M R Chowdhury, M M H Khan, S U Mahfuz, M A Baset
The objective of the study was to evaluate the effects of spices on forage utilization and nitrogen (N) emission using in vitro and in vivo approach. A 6 × 5 factorial triplicate arrangement was used to assess the in vitro degradability of rice straw with control (without spices) and individual (40 mg/g rice straw) spices (cumin, coriander, clove, black cumin, turmeric) at five different incubation times. In vitro dry matter (DM) and organic matter (OM) degradability of rice straw were highest in presence of spices except for clove...
October 13, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29027698/buffalo-heifers-selected-for-lower-residual-feed-intake-have-lower-feed-intake-better-dietary-nitrogen-utilisation-and-reduced-enteric-methane-production
#16
V K Sharma, S S Kundu, C Datt, S Prusty, M Kumar, U B Sontakke
This study was conducted to evaluate the utilisation of the residual feed intake (RFI) as a feed efficiency selection tool and its relationship with methane emissions. Eighteen Murrah buffalo (Bubalus bubalis) heifers were fed ad libitum with total mixed ration (TMR) for 120 days. Based on linear regression models involving dry matter intake (DMI), average daily gain (ADG) and mid-test metabolic body size (MBW(0.75) ), heifers were assigned into low and high RFI groups. The RFI varied from -0.09 to +0.12 kg DM/day with average RFI of -0...
October 13, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29027544/long-term-effects-of-exercise-and-physical-therapy-in-people-with-parkinson-disease
#17
REVIEW
Margaret K Mak, Irene S Wong-Yu, Xia Shen, Chloe L Chung
Parkinson disease (PD) is a progressive, neurodegenerative movement disorder with symptoms reflecting various impairments and functional limitations, such as postural instability, gait disturbance, immobility and falls. In addition to pharmacological and surgical management of PD, exercise and physical therapy interventions are also being actively researched. This Review provides an overview of the effects of PD on physical activity - including muscle weakness, reduced aerobic capacity, gait impairment, balance disorders and falls...
October 13, 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/29027457/gravimetric-standard-gas-mixtures-for-global-monitoring-of-atmospheric-sf6
#18
Jeong Sik Lim, Jinbok Lee, Dongmin Moon, Jin Seog Kim, Jeongsoon Lee, Bradley D Hall
In this study, standard gas mixtures of SF6 in synthetic air were gravimetrically developed as a suite consisting of 6 mixtures with mole fractions of SF6 ranging from 5 to 15 pmol/mol. For precision in weighing the gas fills, an automatic weighing system coupled with a high sensitivity mass balance was used and a gravimetry precision of 3 mg (2σ) was achieved. Impurity profiles of the raw gases were determined by various analyzers. In particular, sub pmol/mol levels of SF6 in the matrix components (N2, O2, and Ar) were carefully measured, since the mole fraction of SF6 in the final step can be significantly biased by this trace amount of SF6 in the raw gases of the matrix components...
October 13, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29027399/early-stage-node-negative-cervical-adenocarcinoma-and-squamous-cell-carcinoma-show-similar-survival-outcomes-after-hysterectomy-a-population-based-study
#19
San Gang Wu, Jia Yuan Sun, Zhen Yu He, Qiong Hua Chen, Juan Zhou
OBJECTIVE: To investigate the clinicopathological features and outcomes between node-negative, early-stage cervical squamous cell carcinoma (SCC) and adenocarcinoma (AC) after hysterectomy. METHODS: Patients diagnosed with International Federation of Gynecology and Obstetrics (FIGO) stages I-IIA cervical SCC and AC between 1988 and 2013 were retrospectively reviewed using the Surveillance, Epidemiology, and End Results database. We used propensity score-matching to balance patient baseline characteristics...
November 2017: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29027396/comparison-of-three-different-risk-stratification-models-for-predicting-lymph-node-involvement-in-endometrioid-endometrial-cancer-clinically-confined-to-the-uterus
#20
Vakkas Korkmaz, Mehmet Mutlu Meydanli, Ibrahim Yalçın, Mustafa Erkan Sarı, Hanifi Sahin, Eda Kocaman, Ali Haberal, Polat Dursun, Tayfun Güngör, Ali Ayhan
OBJECTIVE: To compare the clinical validity of the Gynecologic Oncology Group-99 (GOG-99), the Mayo-modified and the European Society for Medical Oncology (ESMO)-modified criteria for predicting lymph node (LN) involvement in women with endometrioid endometrial cancer (EC) clinically confined to the uterus. METHODS: A total of 625 consecutive women who underwent comprehensive surgical staging for endometrioid EC clinically confined to the uterus were divided into low- and high-risk groups according to the GOG-99, the Mayo-modified, and the ESMO-modified criteria...
November 2017: Journal of Gynecologic Oncology
keyword
keyword
100304
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"