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https://www.readbyqxmd.com/read/28317315/uptake-of-wheel-filtration-among-clients-of-a-supervised-injecting-facility-can-structured-education-work
#1
Maureen Steele, Edmund Silins, Ian Flaherty, Sarah Hiley, Nick van Breda, Marianne Jauncey
INTRODUCTION AND AIMS: Wheel-filtration of pharmaceutical opioid tablets is a recognised harm reduction strategy, but uptake of the practice among people who inject drugs is low. The study aimed to: (i) examine perceptions of filtration practices; (ii) provide structured education on wheel-filtration; and (iii) assess uptake of the practice. DESIGN AND METHODS: Frequent opioid tablet injectors (n = 30) attending a supervised injecting facility in Sydney, Australia, received hands-on instruction on wheel-filtration based on recommended practice...
March 20, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/28315479/biopsychosocial-influence-on-shoulder-pain-rationale-and-protocol-for-a-pre-clinical-trial
#2
Steven Z George, Roland Staud, Paul A Borsa, Samuel S Wu, Margaret R Wallace, Warren H Greenfield, Lauren N Mackie, Roger B Fillingim
BACKGROUND: Chronic musculoskeletal pain conditions are a prevalent and disabling problem. Preventing chronic musculoskeletal pain requires multifactorial treatment approaches that address its complex etiology. Prior cohort studies identified a high risk subgroup comprised of variation in COMT genotype and pain catastrophizing. This subgroup had increased chance of heightened pain responses (in a pre-clinical model) and higher 12month post-operatives pain intensity ratings (in a clinical model)...
March 14, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28296898/a-new-survey-to-evaluate-conflict-of-interest-policies-at-academic-medical-centers
#3
Marcia Hams, Wells G Wilkinson, Lynn Zentner, Cory Schmidt, Raed A Dweik, Matthew Karafa, Susannah L Rose
BACKGROUND: A majority of academic medical centers (AMCs) have now adopted conflict of interest policies (COI) to address relationships with pharmaceutical and device industries that can increase the risk of bias in patient care, education and research. However, AMCs may have little information on the impact of their policies. This paper provides a new method, which is a free, publicly-available survey, to fill this information gap and improve COI programs at AMCs. METHODS & FINDINGS: The survey, piloted in three AMCs and designed in collaboration with national conflicts of interest policy experts, covers a range of universal compliance-related concerns, which allows institutions to tailor questions to align with their own policies and culture...
2017: PloS One
https://www.readbyqxmd.com/read/28281091/accuracy-and-readability-of-websites-on-kidney-and-bladder-cancers
#4
Samy A Azer, Maha M Alghofaili, Rana M Alsultan, Najla S Alrumaih
The aim of this study was to assess the scientific accuracy and the readability level of websites on kidney and bladder cancers. The search engines Google™, Yahoo™ and Bing™ were searched independently by assessors in November 2014 using the following keywords: "bladder cancer", "kidney cancer", "patient bladder cancer", "patient kidney cancer" and "bladder and kidney cancer". Only English-language websites were selected on the bases of predetermined inclusion and exclusion criteria. Assessors independently reviewed the findings and evaluated the accuracy and quality of each website by using the DISCERN and the LIDA instruments...
March 9, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/28262371/-cooperation-according-to-french-law-hospital-patients-health-and-territories-pharmacists-involvement-in-aquitaine-region
#5
M d'Elbée, M Baumevieille, C Dumartin
BACKGROUND: In 2009, the French Act "Hospital, Patients, Health and Territories" (loi "Hôpital, Patients, Santé et Territoires") reorganized the outpatient care pathway and defined missions aimed at improving cooperation between pharmaceutical and medical professionals. Five years later, we conducted a survey among community pharmacists in order to assess the appropriation of these missions and the way cooperation was implemented. We also aimed to investigate factors that could hamper or ease the development of these activities in order to identify actions needed to improve pharmacists' involvement...
March 2, 2017: Revue D'épidémiologie et de Santé Publique
https://www.readbyqxmd.com/read/28260280/teaching-rational-prescribing-to-general-practice-registrars-a-guide-for-supervisors
#6
Simon Morgan
BACKGROUND: Pharmaceuticals play an important role in modern day healthcare, and prescribing is a very common activity in Australian general practice. However, there are significant harms associated with medicine use. Vocational training is a critical period in the development of clinical practice patterns for the future general practitioner (GP), including prescribing behaviour. The general practice supervisor, therefore, has a key role to play in educating registrars about rational prescribing...
March 2017: Australian Family Physician
https://www.readbyqxmd.com/read/28253393/comparison-of-pharmaceutical-psychological-and-exercise-treatments-for-cancer-related-fatigue-a-meta-analysis
#7
Karen M Mustian, Catherine M Alfano, Charles Heckler, Amber S Kleckner, Ian R Kleckner, Corinne R Leach, David Mohr, Oxana G Palesh, Luke J Peppone, Barbara F Piper, John Scarpato, Tenbroeck Smith, Lisa K Sprod, Suzanne M Miller
Importance: Cancer-related fatigue (CRF) remains one of the most prevalent and troublesome adverse events experienced by patients with cancer during and after therapy. Objective: To perform a meta-analysis to establish and compare the mean weighted effect sizes (WESs) of the 4 most commonly recommended treatments for CRF-exercise, psychological, combined exercise and psychological, and pharmaceutical-and to identify independent variables associated with treatment effectiveness...
March 2, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28250328/local-pharmacy-pharmacists-responses-to-the-prescription-of-drugs-that-influence-driving
#8
Taizo Nagata, Junichi Yamada, Hitoshi Oohara, Junko Kizu
 In 2013, the Ministry of Health, Labour, and Welfare issued a notification regarding drugs that influence driving. Afterward, a questionnaire survey of these drugs was conducted involving health insurance pharmacies in Tokyo and Shiga Prefectures. As a result, 503 (Tokyo) and 116 (Shiga) pharmacies provided completed questionnaires. The notification was sufficiently and slightly recognized by 20% and 44% of the surveyed pharmacies, respectively, and drugs with a driving-related warning were recognized by 31% of the pharmacies...
2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28250327/patients-taking-antihistamines-and-their-effects-on-driving
#9
Junko Kizu
 Sleepiness is known as one of the side effects of antihistamines, and impaired performance caused by these drugs has become problematic. Among the 13 second-generation antihistamines causing sleepiness to some extent, the package inserts of 8 drugs prohibit driving, 3 stress driving with care, and 2 give no driving-related warning. It was confirmed that the description did not necessarily reflect the results of the standard deviation of lateral position measurement study, which is considered the most effective study for evaluating the effects of drugs on automobile driving...
2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28239024/in-practical-training-a-questionnaire-survey-and-analysis-to-pharmacy-students-of-the-utilization-situation-of-the-course-contents-of-pharmacy-school
#10
Masato Okubo, Yuka Takahashi, Jun Yamashita, Hideyo Takahashi, Okiko Miyata, Takaaki Suzuki, Itsuko Ishii
  Pharmacy education comprises basic pharmacy (organic chemistry, biochemistry, and physical chemistry) and applied pharmacy (clinical pharmacy, pharm aceutics, and chemical hygiene). Students are expected to apply these subjects studied in pharmacy school during their practical pharmacy training. However, knowledge gained in university does not appear to be fully utilized in practice. We hypothesized that this is due to a lack of connection between pre-practical training education and actual practical training...
February 24, 2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28228230/expanding-professional-pharmacy-services-in-european-community-setting-is-it-cost-effective-a-systematic-review-for-health-policy-considerations
#11
REVIEW
Clémence Perraudin, Olivier Bugnon, Nathalie Pelletier-Fleury
OBJECTIVE: To synthesize cost-effectiveness analyses on professional pharmacy services (PPS) performed in Europe in order to contribute to current debates on their funding and reimbursement. METHODS: Systematic review in PubMed, Embase and the Centre for Reviews and Dissemination databases to identify full economic evaluation studies of PPS in community setting from 2004. FINDINGS: Twenty-one studies were included, conducted in the United-Kingdom (n=13), the Netherlands (n=3), Spain (n=2), Belgium (n=1), France (n=1) and Denmark (n=1)...
December 2016: Health Policy
https://www.readbyqxmd.com/read/28226336/educational-outreach-to-opioid-prescribers-the-case-for-academic-detailing
#12
Margot Trotter Davis, Brian Bateman, Jerry Avorn
Nonmedical use of opioid medications constitutes a serious health threat as the rates of addiction, overdoses, and deaths have risen in recent years. Increasingly, inappropriate and excessively liberal prescribing of opioids by physicians is understood to be a central part of the crisis. Public health officials, hospital systems, and legislators are developing programs and regulations to address the problem in sustained and systematic ways that both insures effective treatment of pain and appropriate limits on the availability of opioids...
February 2017: Pain Physician
https://www.readbyqxmd.com/read/28224361/modeling-strategy-to-identify-patients-with-primary-immunodeficiency-utilizing-risk-management-and-outcome-measurement
#13
Vicki Modell, Jessica Quinn, Grant Ginsberg, Ron Gladue, Jordan Orange, Fred Modell
This study seeks to generate analytic insights into risk management and probability of an identifiable primary immunodeficiency defect. The Jeffrey Modell Centers Network database, Jeffrey Modell Foundation's 10 Warning Signs, the 4 Stages of Testing Algorithm, physician-reported clinical outcomes, programs of physician education and public awareness, the SPIRIT® Analyzer, and newborn screening, taken together, generates P values of less than 0.05%. This indicates that the data results do not occur by chance, and that there is a better than 95% probability that the data are valid...
February 21, 2017: Immunologic Research
https://www.readbyqxmd.com/read/28212657/pharmacists-views-and-reported-practices-in-relation-to-a-new-generic-drug-substitution-policy-in-lebanon-a-mixed-methods-study
#14
Fadi El-Jardali, Racha Fadlallah, Rami Z Morsi, Nour Hemadi, Mounir Al-Gibbawi, Magda Haj, Suzan Khalil, Youssef Saklawi, Diana Jamal, Elie A Akl
BACKGROUND: Governments in both developed and developing countries have adopted generic drug substitution policies to decrease pharmaceutical expenditures and improve access to medicine. In August 2015, the Ministry of Public Health (MOPH) in Lebanon introduced generic drug substitution and a unified medical prescription form as policy instruments to promote generic drug use. The objective of this exploratory study was to examine the attitudes of community pharmacists and the reported practices in relation to the implementation of the new generic drug substitution policy...
February 17, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28211842/assessment-of-upper-limb-musculoskeletal-pain-and-posture-in-workers-of-packaging-units-of-pharmaceutical-industries
#15
Yasser Labbafinejad, Hossein Danesh, Zahra Imanizade
BACKGROUND: Work-related musculoskeletal disorders are defined as the disabling or painful injury to the muscles, nerves or tendons that are caused by work or aggravated by it. Some studies confirm the association between working in packaging units in various industries and the pain in the upper limb, but also there are controversies about the possible risk factors among different working populations. OBJECTIVE: The present study aims to define the potential ergonomic risk factors for musculoskeletal pain in the upper limb...
February 17, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/28194338/development-of-medical-writing-in-india-past-present-and-future
#16
REVIEW
Suhasini Sharma
Pharmaceutical medical writing has grown significantly in India in the last couple of decades. It includes preparing regulatory, safety, and publication documents as well as educational and communication material related to health and health-care products. Medical writing requires medical understanding, knowledge of drug development and the regulatory and safety domains, understanding of research methodologies, and awareness of relevant regulations and guidelines. It also requires the ability to analyze, interpret, and present biomedical scientific data in the required format and good writing skills...
January 2017: Perspectives in Clinical Research
https://www.readbyqxmd.com/read/28192219/a-qualitative-study-of-overweight-and-obese-australians-views-of-food-addiction
#17
A J Cullen, A Barnett, P A Komesaroff, W Brown, K S O'Brien, W Hall, A Carter
The concept of food addiction is increasingly used in the academic literature and popular media to explain some forms of overweight and obesity. However, there is limited evidence on how this term is understood by and impacts overweight and obese individuals. This qualitative study investigated the views of overweight and obese individuals on food addiction, and its likely impact upon stigma, treatment-seeking, and support for public policies to reduce overeating. Semi-structured interviews were conducted with 23 overweight and obese individuals (Mage = 38, MBMI = 33, 74% female) and analysed thematically...
February 10, 2017: Appetite
https://www.readbyqxmd.com/read/28191318/structured-pharmaceutical-care-improves-the-health-related-quality-of-life-of-patients-with-asthma
#18
Philip O Anum, Berko P Anto, Audrey G Forson
BACKGROUND: Asthma as a chronic health condition can be controlled when in addition to clinical care, adequate education and support is provided to enhance self-management. Like many other chronic health conditions improved self-management positively impacts the health-related quality of life (HRQoL). It can therefore be said that a well-structured pharmaceutical care delivery that addresses the issues related to patient education and support towards self-management stands a good chance of positively impacting asthma control...
2017: Journal of Pharmaceutical Policy and Practice
https://www.readbyqxmd.com/read/28190479/a-global-picture-of-pharmacy-technician-and-other-pharmacy-support-workforce-cadres
#19
Tamara Koehler, Andrew Brown
INTRODUCTION: Understanding how pharmacy technicians and other pharmacy support workforce cadres assist pharmacists in the healthcare system will facilitate developing health systems with the ability to achieve universal health coverage as it is defined in different country contexts. The aim of this paper is to provide an overview of the present global variety in the technician and other pharmacy support workforce cadres considering; their scope, roles, supervision, education and legal framework...
March 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28182663/dihydrobenz-e-1-4-oxazepin-2-3h-ones-a-new-anthelmintic-chemotype-immobilising-whipworm-and-reducing-infectivity-in-vivo
#20
Frederick A Partridge, Emma A Murphy, Nicky J Willis, Carole J R Bataille, Ruth Forman, Narinder Heyer-Chauhan, Bruno Marinič, Daniel J C Sowood, Graham M Wynne, Kathryn J Else, Angela J Russell, David B Sattelle
Trichuris trichiura is a human parasitic whipworm infecting around 500 million people globally, damaging the physical growth and educational performance of those infected. Current drug treatment options are limited and lack efficacy against the worm, preventing an eradication programme. It is therefore important to develop new treatments for trichuriasis. Using Trichuris muris, an established model for T. trichiura, we screened a library of 480 novel drug-like small molecules for compounds causing paralysis of the ex vivo adult parasite...
February 2017: PLoS Neglected Tropical Diseases
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