Bi-Wen Cheng, Fu-Sung Lo, An-Mei Wang, Chen-Mei Hung, Chi-Yu Huang, Wei-Hsin Ting, Mei-Ore Yang, Chao-Hsu Lin, Chia-Ching Chen, Chiung-Ling Lin, Yi-Lei Wu, Yann-Jinn Lee
We investigated the prevalence of glutamic acid decarboxylase 65 autoantibody (GADA), insulinoma-associated protein 2 autoantibody (IA2A), and insulin autoantibody (IAA) in 750 children with type 1 diabetes (T1D) living in Taiwan. GADA, IA2A, and IAA were measured by radioimmunoassay. The data were assessed by χ 2 test, binary logistic regression, and Spearman rank correlation. Of the 750 T1D patients, 66.3% had GADA, 65.3% IA2A, 35.7% IAA, and 17.2% no autoantibodies. The prevalence of GADA and IA2A significantly decreased along T1D duration...
March 27, 2018: Oncotarget