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Burcu Örmeci, Egemen Avcı, Çigdem Kaspar, Özlem Eranıl Terim, Tibet Erdoğru, A Emre Öge
OBJECTIVE: To examine the diagnostic value of pudendal somatosensory evoked potentials (SEPs) in pudendal nerve entrapment (PNE) neuropathy by stimulating the 2 sides separately after provocation by a standard sitting position. Routine pudendal SEPs performed in the supine position with bilateral simultaneous stimulation may fail to show the abnormality because the complaints of PNE appear or worsen in the sitting position. METHODS: Forty-nine patients with PNE and 16 controls were included...
January 2017: Urology
Jeffrey J Ellis, Alesia B Sadosky, Laura L Ten Eyck, Pallavi Mudumby, Joseph C Cappelleri, Lilian Ndehi, Brandon T Suehs, Bruce Parsons
BACKGROUND: Anticipating and controlling drug-drug interactions (DDIs) in older patients with painful diabetic peripheral neuropaty (pDPN) presents a significant challenge to providers. The purpose of this study was to examine the impact of newly initiated pregabalin or duloxetine treatment on Medicare Advantage Prescription Drug (MAPD) plan pDPN patients' encounters with potential drug-drug interactions, the healthcare cost and utilization consequences of those interactions, and opioid utilization...
April 15, 2015: BMC Health Services Research
Ravi Kant Upadhyay
Present review highlights various drug delivery systems used for delivery of pharmaceutical agents mainly antibiotics, antineoplastic agents, neuropeptides, and other therapeutic substances through the endothelial capillaries (BBB) for CNS therapeutics. In addition, the use of ultrasound in delivery of therapeutic agents/biomolecules such as proline rich peptides, prodrugs, radiopharmaceuticals, proteins, immunoglobulins, and chimeric peptides to the target sites in deep tissue locations inside tumor sites of brain has been explained...
2014: BioMed Research International
Koji Abe, Shinichiro Uchiyama, Etsuro Matsubara, Shin-Ichi Muramatsu, Naoki Atsuta, Kazuo Kitagawa, Yasuyuki Iguchi, Hiroaki Ooboshi, Ryuji Kaji, Yasuo Terao
On March 11, 2011, big earthquake and subsequent gigantic tsunami killed more than 20,000 peoples in Tohoku area of Japan. Neurological patients were one such victim because they are usually very vulnerable to such a huge tragedy due to their physical disability including artificial ventilator-support. On occasion of the last tsunami, most cases showed "all or nothing" to lose life or to survive, and there were only a little cases who needed emergency surgical treatment. In the very early period, some neurological patients required electric power to keep their lifesupportive ventilator at evacuation house or even at home...
2013: Rinshō Shinkeigaku, Clinical Neurology
Małgorzata Bilińska, Lidia Usnarska-Zubkiewicz, Małgorzata Szymczyk, Leszek Noga, Stanislaw Potoczek, Kazimierz Kuliczkowski, Ryszard Podemski
UNLABELLED: Chemotherapy-induced sensory neuropathies differ in clinical picture. There is predominance of paresthesiae in some of them while in others pain or deep sensation failure can dominate. THE AIM OF THE STUDY: To perform the clinical and electrophysiological assessment of peripheral sensory nerves in patients with multiple myeloma (m.m.) treated with thalidomide. Special attention was directed to function of subtypes of sensory fibres which convey different modalities of sensation...
August 2011: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
Liliana-Cerasela Tataru, D Zaharia, Ana Stratone
MATERIAL AND METHOD: 20 patients were examined (40 eyes) with different ophthalmic affections, age between 57 and 72 years old, 15 female and 5 male. RESULTS: Visual acuity was evaluated between 0.00 and 1.00 with correction. The laboratory exploration reveals changes of the lipidic profile--in 20% cases and the glucidic profile--in 12.50% cases. The inflammatory aspect also has been changed (the erytrocite sedimentation rate, the fibrinogen, reactive C protein)-- cases...
April 2009: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
O Lasso Luis, J Galán Morales, M J Herguido Bóveda, J Andrés Ares, M J Alamo Rodríguez
This article report four cases of schwannomas originating in the cervical peripheral nervous branches, which were operated by ENT Department between 1991 and 2004. The difficulty on differential diagnosis and possible complications after the surgery are commented. Speaking of these cases, reference is done about the manage of post surgical neuropathy, very common after interventions on neural or perineural tumour of orocervicofacial area.
2006: Anales Otorrinolaringológicos Ibero-americanos
Lu Gaohua, Tsuyoshi Maekawa, Hidenori Kimura
Brain hypothermia treatment (BHT) is an intensive care characterized by simultaneous managements of various vital signs, such as intracranial temperature (ICT) and pressure (ICP), of the severe neuropatient. Medical treatments including therapeutic ambient cooling and diuresis are separately carried out based on the experience of the medical staff involved in the clinical management of various pathophysiological processes, such as thermodynamics, hemodynamics and pharmacokinetics. However, no special attention has been paid to the interactions among these subsystems in therapeutic hypothermia because of the lack of theoretical knowledge...
September 7, 2006: Journal of Theoretical Biology
Lu Gaohua, Hidenori Kimura
Brain hypothermia treatment is used as a neuroprotectant to decompress the elevated intracranial pressure (ICP) in acute neuropatients. However, a quantitative relationship between decompression and brain hypothermia is still unclear, this makes medical treatment difficult and ineffective. The objective of this paper is to develop a general mathematical model integrating hemodynamics and biothermal dynamics to enable a quantitative prediction of transient responses of elevated ICP to ambient cooling temperature...
February 21, 2006: Journal of Theoretical Biology
G Sobue
Wide variety of underlying mechanisms are present for pathogenesis and pathophysiology of neuropaties, some of the which are being elucidated recently. Remarkable recent advances are discovery of causative gene mutations of various hereditary neuropathies and elucidation of pathogenic mechanism of inflammatory demyelinating neuropathy. Particularly, causative gene mutations for Charcot-Marie-Tooth (CMT) disease and pathogenic role of glycolipid antigens for Guillain-Barré syndrome have recently been documented...
December 1999: Rinshō Shinkeigaku, Clinical Neurology
G B Krohel, J R Richardson, D F Farrell
Atypical facial pain and permanent sensory loss in the second and third divisions of the trigeminal nerve developed in a patient who had had multiple attacks of herpes simplex neuralgia over a period of 8 years. Intravenous cytosine arabinoside failed to prevent a recurrence of the vasicular eruption, but carbamazepine produced symtomatic pain relief. This case demonstrates that herpes simplex can closely mimic herpes zoster as a cause of postherpetic neuralgia and suggests a possible etiology of atypical facial pain and/or trigeminal sensory neuropaty in some patients...
June 1976: Neurology
P F Moreira Filhio, M R de Freitas, M L Caldas, E Almeida
The case of a 67 years old woman with giant cell arteritis and neuritis multiplex is reported. The diagnosis was based on the microscopic appearances of temporal artery biopsy specimens. The authors described the involvement of peripheral nerves in this disease and made differential diagnosis with polyarteritis nodosa. There was also hemorragic infarction of the brain without giant-cells in brain vessels. It is concluded that this diagnosis should be considered in any elderly patient with peripheral neuropathy...
September 1978: Arquivos de Neuro-psiquiatria
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