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Raquel-Kathrin Prüllage, Kent Urban, Edgar Schäfer, Till Dammaschke
INTRODUCTION: The aim was to compare the solubility, radiopacity, and setting times of a tricalcium silicate-containing (BioRoot RCS; Septodont, St Maur-des-Fossés, France) and a mineral trioxide aggregate-containing sealer (MTA Fillapex; Angelus, Londrina, Brazil) with an epoxy resin-based sealer (AH Plus; Dentsply DeTrey, Konstanz, Germany). METHODS: Solubility in distilled water, radiopacity, and setting time were evaluated in accordance with ISO-6876:2012. The solubility was also measured after soaking the materials in phosphate-buffered saline buffer (PBS)...
October 18, 2016: Journal of Endodontics
Jessica Schweitzer, Jennifer Vermeesch, Theresa Zaleski, Megan Iacco, Kent Krach, Jessica Ghaferi, Jenny Cotton
No abstract text is available yet for this article.
September 2016: JAAD Case Reports
John L Semple, G W Kent Moore, Petros Koutrakis, Jack M Wolfson, Paolo Cristofanelli, Paolo Bonasoni
: Semple, John L., G.W. Kent Moore, Petros Koutrakis, Jack M. Wolfson, Paolo Cristofanelli, and Paolo Bonasoni. High concentrations of ozone air pollution on Mount Everest: health implications for Sherpa communities and mountaineers. High Alt Med Biol. 00:000-000, 2016.-Introduction: Populations in remote mountain regions are increasingly vulnerable to multiple climate mechanisms that influence levels of air pollution. Few studies have reported on climate-sensitive health outcomes unique to high altitude ecosystems...
October 20, 2016: High Altitude Medicine & Biology
Janice C Zgibor, Elizabeth A Schlenk, Laura Vater, Sushma Kola, Joni Vander Bilt, Sarah Woody, Mini E Jacob, Wei-Hsuan Lo-Ciganic, Allison Brenckle, Jane Brandenstein, C Kent Kwoh, Robert Boudreau, Steven Albert, Margaret Conroy, Elizabeth Rodgers, Anne B Newman
BACKGROUND: Evidence-based interventions exist for prevention of chronic disease in older adults. Partnering with community organizations may provide a mechanism for disseminating these interventions. OBJECTIVE: To describe the partnership and program implementation by the Arthritis Foundation (AF) and the University of Pittsburgh. METHODS: The AF Exercise Program (AFEP; an existing evidence-based program) was enhanced with the "10 Keys"™ to Healthy Aging (a prevention-focused program bundling the most common risk factors for chronic disease and disability in older adults and applies behavior change strategies to enhance prevention)...
2016: Progress in Community Health Partnerships: Research, Education, and Action
(no author information available yet)
This simple-to-use app is a useful resource for all those supporting victims of abuse, and offers particular local information for Kent.
October 12, 2016: Nursing Standard
Hanne Gro Olsen, Tim Martin Knutsen, Anna M Lewandowska-Sabat, Harald Grove, Torfinn Nome, Morten Svendsen, Mariann Arnyasi, Marte Sodeland, Kristil K Sundsaasen, Sandra Rinne Dahl, Bjørg Heringstad, Hanne H Hansen, Ingrid Olsaker, Matthew Peter Kent, Sigbjørn Lien
BACKGROUND: Clinical mastitis is an inflammation of the mammary gland and causes significant costs to dairy production. It is unfavourably genetically correlated to milk production, and, thus, knowledge of the mechanisms that underlie these traits would be valuable to improve both of them simultaneously through breeding. A quantitative trait locus (QTL) that affects both clinical mastitis and milk production has recently been fine-mapped to around 89 Mb on bovine chromosome 6 (BTA6), but identification of the gene that underlies this QTL was not possible due to the strong linkage disequilibrium between single nucleotide polymorphisms (SNPs) within this region...
October 19, 2016: Genetics, Selection, Evolution: GSE
Michael J Manfredo, Jeremy T Bruskotter, Tara L Teel, David Fulton, Shalom H Schwartz, Robert Arlinghaus, Shigehiro Oishi, Ayse K Uskul, Kent Redford, Shinobu Kitayama, Leeann Sullivan
The hope for creating widespread change in social values has endured among conservation professionals since early calls by Aldo Leopold for a "Land Ethic". However, there has been little serious attention in conservation to the fields of investigation that address values, how they are formed, and how they change. We introduce a social-ecological systems approach in which values are seen not just as motivational goals that people hold, but they are also deeply embedded in the world around us, in our material culture, collective behaviors, traditions, and social institutions...
October 19, 2016: Conservation Biology: the Journal of the Society for Conservation Biology
Saud M Alsanad, Rachel L Howard, Elizabeth M Williamson
BACKGROUND: Herb/Dietary Supplements (HDS) are the most popular Complementary and Alternative Medicine (CAM) modality used by cancer patients and the only type which involves the ingestion of substances which may interfere with the efficacy and safety of conventional medicines. This study aimed to assess the level of use of HDS in cancer patients undergoing treatment in the UK, and their perceptions of their effects, using 127 case histories of patients who were taking HDS. Previous studies have evaluated the risks of interactions between HDS and conventional drugs on the basis on numbers of patient using HDSs, so our study aimed to further this exploration by examining the actual drug combinations taken by individual patients and their potential safety...
October 18, 2016: BMC Complementary and Alternative Medicine
Athol Kent, Shona Kirtley
No abstract text is available yet for this article.
November 2016: BJOG: An International Journal of Obstetrics and Gynaecology
Pravin Kesarwani, Paramita Chakraborty, Radhika Gudi, Shilpak Chatterjee, Gina Scurti, Kyle Toth, Patt Simms, Mahvash Husain, Kent Armeson, Shahid Husain, Elizabeth Garrett-Mayer, Chethamarakshan Vasu, Michael I Nishimura, Shikhar Mehrotra
Advancements in adoptive cell transfer therapy (ACT) has led to the use of T cells engineered with tumor specific T cell receptors, which after rapid expansion can be obtained in sufficient numbers for treating patients. However, due to massive proliferation these cells are close to replicative senescence, exhibit exhausted phenotype, and also display increased susceptibility to activation induced cell death. We have previously shown that tumor reactive T cells undergo caspase-independent cell death upon TCR restimulation with cognate antigen, which involves reactive oxygen species and c-jun N-terminal kinase...
October 14, 2016: Oncotarget
Michael S Kent, Davide Berlato, Isabelle Vanhaezebrouck, Ira K Gordon, Katherine S Hansen, Alain P Theon, Randall W Holt, Earl A Trestrail
Radiation therapy of the head and neck can result in mucositis and other acute affects in the oral cavity. This prospective pilot study evaluated a novel, intraoral, beam-blocking device for use during imaging and therapeutic procedures. The beam-blocking device was made from a metal alloy inserted into a coated frozen dessert mold (Popsicle® Mold, Cost Plus World Market, Oakland, CA). The device was designed so that it could be inserted into an outer shell, which in turn allowed it to be placed or removed depending on the need due to beam configuration...
October 17, 2016: Veterinary Radiology & Ultrasound
Dimitrios A Pappas, Jeffrey D Kent, Jeffrey D Greenberg, Marc A Mason, Joel M Kremer, Robert J Holt
INTRODUCTION: The goal of this study was to evaluate how frequently rheumatoid arthritis (RA) therapy is instituted promptly and to describe the characteristics of patients who are not treated early upon diagnosis. METHODS: The percentage of patients who at the time of enrollment in the Corrona registry were not receiving any RA-directed therapy was evaluated and their characteristics were summarized. The time to subsequent initiation of any RA-directed therapy was also estimated...
December 2015: Rheumatol Ther
Mahmoud Masoud, Erhan Kozan, Geoff Kent, Shi Qiang Liu
The freight rail systems have an essential role to play in transporting the commodities between the delivery and collection points at different locations such as farms, factories and mills. The fright transport system uses a daily schedule of train runs to meet the needs of both the harvesters and the mills (An Integrated Approach to Optimise Cane Rail Operations (M. Masoud, E. Kozan, G. Kent, Liu, Shi Qiang, 2016b) [1]). Producing an efficient daily schedule to optimise the rail operations requires integration of the main elements of harvesting, transporting and milling in the value chain of the Australian agriculture industry...
December 2016: Data in Brief
Yohei Komaru, Kent Doi
No abstract text is available yet for this article.
September 2016: Journal of Thoracic Disease
Nadia Gildeh, Panagis Drakatos, Sean Higgins, Ivana Rosenzweig, Brian D Kent
Obstructive sleep apnea (OSA) causes daytime fatigue and sleepiness, and has an established relationship with cardiovascular and metabolic disease. Recent years have seen the emergence of an evidence base linking OSA with an increased risk of degenerative neurological disease and associated cognitive impairment, an accelerated rate of decline in kidney function with an increased risk of clinically significant chronic kidney disease (CKD), and with a significantly higher rate of cancer incidence and death. This review evaluates the evidence base linking OSA with these seemingly unrelated co-morbidities, and explores potential mechanistic links underpinning their development in patients with OSA, including intermittent hypoxia (IH), sleep fragmentation, sympathetic excitation, and immune dysregulation...
September 2016: Journal of Thoracic Disease
James Small, Catherine Flanagan, Kent Armeson, David Perry, Richard Marchell, Bruce Thiers, Anthony J Alberg
No abstract text is available yet for this article.
November 2016: Journal of the American Academy of Dermatology
Jenna N Harvestine, Nina L Vollmer, Steve S Ho, Christopher Andrew Zikry, Mark A Lee, J Kent Leach
Composite scaffolds of bioactive glass and poly(lactide-co-glycolide) provide advantages over homogenous scaffolds, yet their therapeutic potential can be improved by strategies that promote adhesion and present instructive cues to associated cells. Mesenchymal stem cell (MSC)-secreted extracellular matrix (ECM) enhances survival and function of associated cells. To synergize the benefits of an instructive ECM with composite scaffolds, we tested the capacity of ECM-coated composite scaffolds to promote cell persistence and resultant osteogenesis...
October 16, 2016: Biomacromolecules
Adam Ralph, Martin Somers, Jonathan Cowman, Bruno Voisin, Emma Hogan, Hannah Dunne, Eimear Dunne, Barry Byrne, Nigel Kent, Antonio J Ricco, Dermot Kenny, Simon Wong
The imaging of shear-mediated dynamic platelet behavior interacting with surface-immobilized von Willebrand factor (vWF) has tremendous potential in characterizing changes in platelet function for clinical diagnostics purposes. However, the imaging output, a series of images representing platelets adhering and rolling on the surface, poses unique, non-trivial challenges for software algorithms that reconstruct the positional trajectories of platelets. We report on an algorithm that tracks platelets using the output of such flow run experiments, taking into account common artifacts encountered by previously-published methods, and we derive seven key metrics of platelet dynamics that can be used to characterize platelet function...
October 14, 2016: Cardiovascular Engineering and Technology
Radek Frič, Erika Kristina Lindstrøm, Geir Andre Ringstad, Kent-André Mardal, Per Kristian Eide
BACKGROUND: In symptomatic Chiari malformation type 1 (CMI), impaired intracranial compliance (ICC) is associated with an increased cranio-spinal pulsatile pressure gradient. Phase-contrast magnetic resonance imaging (MRI) represents a non-invasive modality for the assessment of the pulse pressure gradient at the cranio-cervical junction (CCJ). We wished to explore how the MRI-derived pulse pressure gradient (MRI-dP) compares with invasively measured pulsatile intracranial pressure (ICP) in CMI, and with healthy controls...
October 14, 2016: Acta Neurochirurgica
Shadpour Demehri, Ali Guermazi, C Kent Kwoh
Osteoarthritis (OA) is a major chronic and global health care problem. Recent technological advances in imaging and postprocessing techniques have enhanced the understanding and characterization of the pathophysiology of this chronic and prevalent disease. Although plain radiograph remains the modality of choice for initial assessment of OA, recent studies have shown that advanced cross-sectional imaging can improve the early detection, grading, structural damage quantification, and risk stratification of OA...
November 2016: Rheumatic Diseases Clinics of North America
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