Jarinda A Poppe, Robert B Flint, Anne Smits, Sten P Willemsen, Kelly K Storm, Debbie H Nuytemans, Wes Onland, Marten J Poley, Willem P de Boode, Katherine Carkeek, Vincent Cassart, Luc Cornette, Peter H Dijk, Marieke A C Hemels, Isabelle Hermans, Matthias C Hütten, Dorottya Kelen, Ellen H M de Kort, André A Kroon, Julie Lefevere, Katleen Plaskie, Breanne Stewart, Michiel Voeten, Mirjam M van Weissenbruch, Olivia Williams, Inge A Zonnenberg, Thierry Lacaze-Masmonteil, Arjan B Te Pas, Irwin K M Reiss, Anton H van Kaam, Karel Allegaert, G Jeroen Hutten, Sinno H P Simons
BACKGROUND: Apnoea of prematurity (AOP) is one of the most common diagnoses among preterm infants. AOP often leads to hypoxemia and bradycardia which are associated with an increased risk of death or disability. In addition to caffeine therapy and non-invasive respiratory support, doxapram might be used to reduce hypoxemic episodes and the need for invasive mechanical ventilation in preterm infants, thereby possibly improving their long-term outcome. However, high-quality trials on doxapram are lacking...
October 10, 2023: Trials