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JOURNAL ARTICLE
Clara Rodrigues, Yasmina Rodríguez, João Frias, Rita Carriço, Paula Sobral, Joana Antunes, Emily M Duncan, Christopher K Pham
Oceanic islands are exposed to plastic debris that has accumulated in the open ocean, particularly in the subtropical gyres. This study investigates the abundance and typology of microplastics (from 0.1 to 5 mm) on 19 sandy beaches spread across 8 oceanic islands of the Azores archipelago. Between January and April 2016, a total of 341 particles retrieved from all beaches, were identified as microplastics. The highest concentration (50.19 ± 21.93 particles kg-1 dw) was found in Terceira Island...
March 20, 2024: Marine Pollution Bulletin
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JOURNAL ARTICLE
Ludmilla de Carvalho Oliveira, Cristina Martinez-Villaluenga, Juana Frias, María Elena Cartea, Marta Francisco, Marcelo Cristianini, Elena Peñas
The impact of different pressure levels in the HHP-assisted hydrolysis by Alcalase of quinoa proteins on the catalytic efficiency, peptide release, phenolic compounds content, and biological activities was investigated. The protein profile (SDS-PAGE) showed a more extensive peptide breakdown for the HHP-assisted proteolysis at 300-400 MPa, which was confirmed by the higher extent of hydrolysis and peptide concentration. Quinoa protein hydrolysates (QPH) produced at 200 and 300 MPa exhibited higher total phenolic contents and antioxidant activities (methanol-acetone and aqueous extracts) when compared to the non-hydrolyzed (QPI) and non-pressurized hydrolyzed samples...
February 29, 2024: Food Chemistry
#23
JOURNAL ARTICLE
Patrick Frias, Rajkamal S Khangura, Bahram Varjavand, Matthew D Alexander
Acute ischemic stroke (AIS) is a debilitating disease for which effective therapies are now available. Effective identification of candidates for therapy relies heavily on noninvasive imaging that must be interpreted accurately in a short timeframe. This review summarizes the evolution of AIS therapies and the implications for noninvasive imaging. The review concludes with consideration of longstanding assumptions about imaging of ischemic stroke and potential paradigm shifts on the horizon.
March 15, 2024: British Journal of Radiology
#24
JOURNAL ARTICLE
Kelley Bemis, Mabel Frias, Sheila Giovanni, Tarek Shackour, Heather D Reid, Jodi Morgan, Michael TeKippe, Demian Christiansen
No abstract text is available yet for this article.
March 14, 2024: MMWR. Morbidity and Mortality Weekly Report
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JOURNAL ARTICLE
Míriam Gómez Villagrá, César Prieto de Frías, Diego Martinez-Acitores de la Mata, Maite Alonso-Sierra, Noelia Alonso-Lazaro, Noemí Caballero, Francisco Sanchez Ceballos, Luis Compañy, Juan Egea Valenzuela, Pilar Esteban, Sergio Farráis, Ignacio Fernández-Urién, Consuelo Galvez, Almudena García, Javier García Lledó, Begoña González Suárez, Victoria-Alejandra Jiménez-García, Marisol Lujan-Sanchís, Beatriz Mateos Muñoz, Cristina Romero-Mascarell, Mileidis San Juan Acosta, Eduardo Valdivielso Cortázar, Antonio Giordano, Cristina Carretero
Background and study aims In 2019, the European Society of Gastrointestinal Endoscopy (ESGE) created a working group to develop technical and quality standards for small-bowel capsule endoscopy (SBCE) to improve the daily practice of endoscopy services. They developed 10 quality parameters, which have yet to be tested in a real-life setting. Our study aimed to evaluate the accomplishment of the quality standards in SBCE established by the ESGE in several Spanish centers. Materials and methods An online survey of 11 multiple-choice questions related to the ESGE performance measures was sent to Spanish centers with experience in SBCE...
March 2024: Endoscopy International Open
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JOURNAL ARTICLE
Caroline Bost, Sabrina Castro-Scholten, Balal Sadeghi, David Cano-Terriza, Mario Frías, Saúl Jiménez-Ruiz, Martin H Groschup, Ignacio García-Bocanegra, Kerstin Fischer
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne zoonotic orthonairovirus of public health concern and widespread geographic distribution. Several animal species are known to seroconvert after infection with CCHFV without showing clinical symptoms. The commercial availability of a multi-species ELISA has led to an increase in recent serosurveillance studies as well as in the range of species reported to be exposed to CCHFV in the field, including wild boar (Sus scrofa). However, development and validation of confirmatory serological tests for swine based on different CCHFV antigens or test principles are hampered by the lack of defined control sera from infected and non-infected animals...
March 12, 2024: Journal of Virological Methods
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JOURNAL ARTICLE
Giorgia Ricchetti, Alba Navarro-Egido, María Rodríguez-Bailón, Daniel Salazar-Frías, Jose Antonio Merchán-Baeza, María Patrocinio Ariza-Vega, María J Funes
IMPORTANCE: Impaired self-awareness (SA) of deficits after an acquired brain injury (ABI) severely affects patients' independence in activities of daily living (ADLs). However, any assessment tool permits an exhaustive evaluation of SA in the context of ADLs. OBJECTIVE: To study the validity of the Breakfast and Dressing Conflict Task (BD Conflict Task) to assess online SA (awareness of performance in the context of a given task) in patients with ABI; to study its interactions with offline SA (general awareness); and to test the validity of a simplified measure of performance monitoring, the ADL Conflict-Monitoring Index...
March 1, 2024: American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association
#28
REVIEW
Tania Vite-Garín, Norma Angélica Estrada-Cruz, Rigoberto Hernández-Castro, Claudia Erika Fuentes-Venado, Paola Berenice Zarate-Segura, María Guadalupe Frías-De-León, Macario Martínez-Castillo, Erick Martínez-Herrera, Rodolfo Pinto-Almazán
Microsporum canis is a widely distributed dermatophyte, which is among the main etiological agents of dermatophytosis in humans and domestic animals. This fungus invades, colonizes and nourishes itself on the keratinized tissues of the host through various virulence factors. This review will bring together the known information about the mechanisms, enzymes and their associated genes relevant to the pathogenesis processes of the fungus and will provide an overview of those virulence factors that should be better studied to establish effective methods of prevention and control of the disease...
February 22, 2024: International Journal of Molecular Sciences
#29
REVIEW
Jan Roland G Molina, Jesús M Frías-Celayeta, Declan J Bolton, Cristina Botinestean
Cured meat products constitute one of the meat categories commonly consumed in Ireland and has been part of the Irish cuisine and diet for many years. Ham, gammon, and bacon are some of the products that involve curing as part of the traditional processing methods. Common among these products are high levels of salt and the addition of nitrites. These products undergo processing treatments to create variety, preserve shelf-life, and develop their unique quality and safety characteristics. However, consumers are becoming more conscious of the level of processing involved in these products, and the effects of some components and ingredients might be perceived as unhealthy...
February 28, 2024: Foods (Basel, Switzerland)
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JOURNAL ARTICLE
Joana Gaifem, Ana Mendes-Frias, Mathis Wolter, Alex Steimle, Maria Jose Garzón, Carles Ubeda, Clarisse Nobre, Abigail González, Salomé S Pinho, Cristina Cunha, Agostinho Carvalho, António Gil Castro, Mahesh S Desai, Fernando Rodrigues, Ricardo Silvestre
UNLABELLED: Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the gastrointestinal tract. The etiology of IBD remains elusive, but the disease is suggested to arise from the interaction of environmental and genetic factors that trigger inadequate immune responses and inflammation in the intestine. The gut microbiome majorly contributes to disease as an environmental variable, and although some causative bacteria are identified, little is known about which specific members of the microbiome aid in the intestinal epithelial barrier function to protect from disease...
March 12, 2024: MBio
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JOURNAL ARTICLE
Jomar N A Aryee, Giulia C Frias, Daniel K Haddad, Kevin D Guerrero, Vivian Chen, Fan Ling, David A Kirschenbaum, James T Monica, Brian M Katt
BACKGROUND: The American Academy of Orthopaedic Surgeons has set forth Clinical Practice Guidelines (CPGs) to help guide management of closed, displaced distal radius fractures (DRFs). There still exists variation in practice regarding operative vs nonoperative decision-making. This study aims to identify which factors influence the decision to treat DRFs not indicated for surgery by the CPGs after initial closed reduction. METHODS: Fifteen sets of DRFs and clinical vignettes were distributed via email to over 75 orthopedic residency programs, Orthopaedic Trauma Association, and New York Society for Surgery of the Hand membership...
March 8, 2024: Hand: Official Journal of the American Association for Hand Surgery
#32
REVIEW
Ángela H Schmolling, Carlos Pérez-García, Carmen Trejo, Alfonso López-Frías, Tanaporn Jaroenngarmsamer, Santiago Rosati, Juan Arrazola, Manuel Moreu
Chronic subdural hematoma (CSDH) is a prevalent medical condition with potentially severe consequences if left untreated. While surgical removal has traditionally been the standard approach for treatment, middle meningeal artery (MMA) embolization has emerged as a promising minimally invasive alternative to reduce recurrences. This comprehensive review provides the general radiology community with an overview of MMA embolization as a therapeutic option for managing CSDH. The authors base their insights on existing evidence and their institutional experience...
April 2024: Radiographics: a Review Publication of the Radiological Society of North America, Inc
#33
JOURNAL ARTICLE
Camilo E Villarroel, Juan C Zenteno, Tania Barragán-Arévalo, Paula Leal-Anaya, Estela Pérez-Muñoz, Christian L Frías-Soria, Eduardo López-Corella, Emiy Yokoyama
Pathogenic variants of the SOHLH1 gene are responsible for an autosomal recessive form of ovarian dysgenesis; this gene encodes a transcription factor expressed early in spermatogonia and oocytes and contributes to folliculogenesis. Previously, four affected women from two unrelated families reported homozygous variants in the SOHLH1 gene, but none had a history of gonadal malignancy or a histologic description. We present two sisters and their paternal great-aunt with a history of primary amenorrhea, pubertal delay, and hypergonadotrophism who came from an inbred Mexican family...
March 6, 2024: Reproductive Sciences
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JOURNAL ARTICLE
Stephen A Harrison, Juan P Frias, K Jean Lucas, Gary Reiss, Guy Neff, Sureka Bollepalli, Yan Su, Doreen Chan, Erik J Tillman, Ali Moulton, Brittany de Temple, Arian Zari, Reshma Shringarpure, Timothy Rolph, Andrew Cheng, Kitty Yale
BACKGROUND & AIMS: In phase 2 studies, efruxifermin, an Fc-FGF21 analog, significantly reduced steatohepatitis and fibrosis in patients with non-alcoholic steatohepatitis (NASH), now called metabolic dysfunction-associated steatohepatitis (MASH), for which there is no approved treatment. Type 2 diabetes (T2D) and obesity are prevalent among patients with MASH and increasingly treated with glucagon-like peptide-1 receptor agonists (GLP-1RAs). This study evaluated the safety and efficacy of efruxifermin in patients with MASH, fibrosis, and T2D taking a GLP-1RA...
March 4, 2024: Clinical Gastroenterology and Hepatology
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JOURNAL ARTICLE
Jorge Sinclair De Frías, Shahin Isha, Lorenzo Olivero, Lekhya Raavi, Sai Abhishek Narra, Smit Paghdar, Sadhana Jonna, Parthkumar Satashia, Rachel Hannon, Jessica Blasavage, Layton White, Titilope Olanipekun, Pankaj Bansal, Sean Kiley, Juan Carlos Leoni, Jose Nativí, Melissa Lyle, Mathew Thomas, Basar Sareyyupoglu, Si Pham, Michael Smith, Pablo Moreno Franco, Parag Patel, Devang Sanghavi
BACKGROUND: Impella is an advanced ventricular assist device frequently used as a bridge to heart transplantation. The association of Impella with increased rates of gout flares has not been studied. Our primary aim is to determine the rates of gout flares in patients on Impella support. METHODOLOGY: A retrospective study was conducted between January 2017 and September 2022 involving all patients who underwent heart transplantation. The cohort was divided into two groups based on Impella support for statistical analysis...
February 29, 2024: BMC rheumatology
#36
JOURNAL ARTICLE
Silvia Bozza, Emilia Nunzi, Abel Frias-Mazuecos, Giuseppe Pieraccini, Marilena Pariano, Giorgia Renga, Antonella Mencacci, Vincenzo Nicola Talesa, Cinzia Antognelli, Paolo Puccetti, Luigina Romani, Claudio Costantini
BACKGROUND: The recent Coronavirus Disease 2019 (COVID-19) pandemic has dramatically exposed our gap in understanding the pathogenesis of airborne infections. Within such a context, it is increasingly clear that the nasal cavity represents a critical checkpoint not only in the initial colonization phase but also in shaping any infectious sequelae . This is particularly relevant to COVID-19 in that the nasal cavity is characterized by high-level expression of the Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2) receptor, Angiotensin-Converting Enzyme 2 (ACE2), all along the respiratory tract...
February 6, 2024: Frontiers in Bioscience (Landmark Edition)
#37
JOURNAL ARTICLE
Laura Costas, Jon Frias-Gomez, Francisco M Peinado, Jose Manuel Molina-Molina, Paula Peremiquel-Trillas, Sonia Paytubi, Marta Crous-Bou, Javier de Francisco, Victor Caño, Yolanda Benavente, Beatriz Pelegrina, José Manuel Martínez, Marta Pineda, Joan Brunet, Xavier Matias-Guiu, Silvia de Sanjosé, Jordi Ponce, Nicolás Olea, Laia Alemany, Mariana F Fernández
BACKGROUND: Endometrial cancer is a hormone-dependent cancer, and estrogens play a relevant role in its etiology. However, little is known about the effects of environmental pollutants that act as xenoestrogens or that influence estrogenic activity through different pathways. OBJECTIVE: We aimed to assess the relationship between the combined estrogenic activity of mixtures of xenoestrogens present in serum samples and the risk of endometrial cancer in the Screenwide case-control study...
February 2024: Environmental Health Perspectives
#38
JOURNAL ARTICLE
Miguel A Frias, Sabrina Pagano, Nasim Bararpour, Jonathan Sidibé, Festus Kamau, Vanessa Fétaud-Lapierre, Peter Hudson, Aurélien Thomas, Sandrine Lecour, Hans Strijdom, Nicolas Vuilleumier
OBJECTIVE: This study aimed to study the relationship between auto-antibodies against apolipoprotein A1 (anti-apoA1 IgG), human immunodeficiency virus (HIV) infection, anti-retroviral therapy (ART), and the tryptophan pathways in HIV-related cardiovascular disease. DESIGN: This case-control study conducted in South Africa consisted of control volunteers ( n = 50), people living with HIV (PLWH) on ART ( n = 50), and untreated PLWH ( n = 44)...
2024: Frontiers in Cardiovascular Medicine
#39
JOURNAL ARTICLE
Baptiste Lemaire, Miguel A Frias, Olivier Golaz, Jean-Luc Magnin, Véronique Viette, Nicolas Vuilleumier, Sophie Waldvogel Abramowski
OBJECTIVES: To determine the ferritin inter-assay differences between three "Conformité Européenne" (CE) marked tests, the impact on reference intervals (RI), and the proportion of individuals with iron deficiency (ID), we used plasma and serum from healthy blood donors (HBD) recruited in three different Switzerland regions. DESIGN AND METHODS: Heparinized plasma and serum from HBD were obtained from three different transfusion centers in Switzerland (Fribourg, Geneva, and Neuchatel)...
February 10, 2024: Diagnostics
#40
JOURNAL ARTICLE
Konstantinos N Fountoulakis, Jelena Vrublevska, Seri Abraham, Kristina Adorjan, Helal Uddin Ahmed, Renato D Alarcón, Kiyomi Arai, Sani Salihu Auwal, Michael Berk, Sarah Bjedov, Julio Bobes, Teresa Bobes-Bascaran, Julie Bourgin-Duchesnay, Cristina Ana Bredicean, Laurynas Bukelskis, Akaki Burkadze, Indira Indiana Cabrera Abud, Ruby Castilla-Puentes, Marcelo Cetkovich, Hector Colon-Rivera, Ricardo Corral, Carla Cortez-Vergara, Piirika Crepin, Domenico De Berardis, Sergio Zamora Delgado, David De Lucena, Avinash De Sousa, Ramona Di Stefano, Seetal Dodd, Livia Priyanka Elek, Anna Elissa, Berta Erdelyi-Hamza, Gamze Erzin, Martin J Etchevers, Peter Falkai, Adriana Farcas, Ilya Fedotov, Viktoriia Filatova, Nikolaos K Fountoulakis, Iryna Frankova, Francesco Franza, Pedro Frias, Tatiana Galako, Cristian J Garay, Leticia Garcia-Álvarez, Maria Paz García-Portilla, Xenia Gonda, Tomasz M Gondek, Daniela Morera González, Hilary Gould, Paolo Grandinetti, Arturo Grau, Violeta Groudeva, Michal Hagin, Takayuki Harada, Tasdik M Hasan, Nurul Azreen Hashim, Jan Hilbig, Sahadat Hossain, Rossitza Iakimova, Mona Ibrahim, Felicia Iftene, Yulia Ignatenko, Matias Irarrazaval, Zaliha Ismail, Jamila Ismayilova, Asaf Jacobs, Miro Jakovljević, Nenad Jakšić, Afzal Javed, Helin Yilmaz Kafali, Sagar Karia, Olga Kazakova, Doaa Khalifa, Olena Khaustova, Steve Koh, Korneliia Kosenko, Sotirios A Koupidis, Alisha Lalljee, Justine Liewig, Abdul Majid, Evgeniia Malashonkova, Khamelia Malik, Najma Iqbal Malik, Gulay Mammadzada, Bilvesh Mandalia, Donatella Marazziti, Darko Marčinko, Stephanie Martinez, Eimantas Matiekus, Gabriela Mejia, Roha Saeed Memon, Xarah Elenne Meza Martínez, Dalia Mickevičiūtė, Roumen Milev, Muftau Mohammed, Alejandro Molina-López, Petr Morozov, Nuru Suleiman Muhammad, Filip Mustač, Mika S Naor, Amira Nassieb, Alvydas Navickas, Tarek Okasha, Milena Pandova, Anca-Livia Panfil, Liliya Panteleeva, Ion Papava, Mikaella E Patsali, Alexey Pavlichenko, Bojana Pejuskovic, Mariana Pinto Da Costa, Mikhail Popkov, Dina Popovic, Nor Jannah Nasution Raduan, Francisca Vargas Ramírez, Elmars Rancans, Salmi Razali, Federico Rebok, Anna Rewekant, Elena Ninoska Reyes Flores, María Teresa Rivera-Encinas, Pilar Saiz, Manuel Sánchez de Carmona, David Saucedo Martínez, Jo Anne Saw, Görkem Saygili, Patricia Schneidereit, Bhumika Shah, Tomohiro Shirasaka, Ketevan Silagadze, Satti Sitanggang, Oleg Skugarevsky, Anna Spikina, Sridevi Sira Mahalingappa, Maria Stoyanova, Anna Szczegielniak, Simona Claudia Tamasan, Giuseppe Tavormina, Maurilio Giuseppe Maria Tavormina, Pavlos N Theodorakis, Mauricio Tohen, Eva Maria Tsapakis, Dina Tukhvatullina, Irfan Ullah, Ratnaraj Vaidya, Johann M Vega-Dienstmaier, Olivera Vukovic, Olga Vysotska, Natalia Widiasih, Anna Yashikhina, Daria Smirnova
BACKGROUND: The COVID-19 pandemic has brought significant mental health challenges, particularly for vulnerable populations, including non-binary gender individuals. The COMET international study aimed to investigate specific risk factors for clinical depression or distress during the pandemic, also in these special populations. METHODS: Chi-square tests were used for initial screening to select only those variables which would show an initial significance. Risk Ratios (RR) were calculated, and a Multiple Backward Stepwise Linear Regression Analysis (MBSLRA) was followed with those variables given significant results at screening and with the presence of distress or depression or the lack of both of them...
February 19, 2024: Journal of Affective Disorders
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