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https://www.readbyqxmd.com/read/29115118/adenomyosis-fertility-and-obstetric-outcome-a-comprehensive-literature-review
#1
Laura Buggio, Ermelinda Monti, Umberto Gattei, Dhohua Dridi, Paolo Vercellini
Adenomyosis is a benign condition characterized by the presence of endometrial glands and stroma deep within the myometrium. In recent years, the potential negative impact of adenomyosis on in vitro fertilization clinical outcomes has gained momentum, as well as, the possible link of this condition with obstetrical complications. The aim of this narrative review is to elucidate the possible association between uterine adenomyosis, infertility, and poor obstetrical outcomes. Several theories have been proposed to clarify the potential harmful impact of adenomyosis on fertility, such as a functional and structural defect of both the eutopic endometrium and the inner myometrium, an impairment of the uterine system of sperm transport, the presence of uterine dysperistalsis and of high levels of free radicals in the uterine milieu of women with the disease...
November 7, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/29070512/debate-identifying-and-treating-subclinical-thyroid-dysfunction-in-pregnancy-emerging-controversies
#2
Ines I Velasco, Peter Nicholas Taylor
Thyroid hormones are essential for an adequate growth and development of the foetus. In addition to the classical association between maternal hypothyroidism and neurological impairment in the progeny, other adverse reproductive events have been associated with maternal thyroid dysfunction including infertility, miscarriage and preterm delivery. Although all scientific societies endorse the treatment of overt hypothyroidism; the management and/or treatment of subclinical hypothyroidism, hypothyroxinemia or antithyroid antibody-positive women should be considered with caution...
October 25, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28856864/pregnancy-outcomes-in-patients-with-uterine-fibroids-treated-with-ultrasound-guided-high-intensity-focused-ultrasound
#3
M Zou, L Chen, C Wu, C Hu, Y Xiong
OBJECTIVE: To investigate the effect of high-intensity focused ultrasound (HIFU) ablation for uterine fibroids on pregnancy. DESIGN: A retrospective observational study. SETTING: Department of Gynaecology in a single centre in China. POPULATION: Patients with uterine fibroids who wish to become pregnant. METHODS: Patients with uterine fibroids who wished become pregnant and have children, were treated using HIFU from April 2011 to March 2016 at Chongqing Haifu Hospital...
August 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28854715/systematic-review-and-meta-analysis-of-the-impact-of-preconception-lifestyle-interventions-on-fertility-obstetric-fetal-anthropometric-and-metabolic-outcomes-in-men-and-women
#4
L Lan, C L Harrison, M Misso, B Hill, H J Teede, B W Mol, L J Moran
STUDY QUESTION: What is the impact of preconception lifestyle interventions on live birth, birth weight and pregnancy rate? SUMMARY ANSWER: Lifestyle interventions showed benefits for weight loss and increased natural pregnancy rate, but not for live birth or birth weight. WHAT IS KNOWN ALREADY: Evidence on the practice and content of preconception counseling and interventions is variable and limited. STUDY DESIGN, SIZE, DURATION: Systematic review and meta-analysis (MA)...
September 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28854592/weight-reduction-intervention-for-obese-infertile-women-prior-to-ivf-a-randomized-controlled-trial
#5
Snorri Einarsson, Christina Bergh, Britt Friberg, Anja Pinborg, Anna Klajnbard, Per-Olof Karlström, Linda Kluge, Ingrid Larsson, Anne Loft, Anne-Lis Mikkelsen-Englund, Kaj Stenlöf, Anna Wistrand, Ann Thurin-Kjellberg
STUDY QUESTION: Does an intensive weight reduction programme prior to IVF increase live birth rates for infertile obese women? SUMMARY ANSWER: An intensive weight reduction programme resulted in a large weight loss but did not substantially affect live birth rates in obese women scheduled for IVF. WHAT IS ALREADY KNOWN: Among obese women, fertility and obstetric outcomes are influenced negatively with increased risk of miscarriage and a higher risk of maternal and neonatal complications...
August 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28446937/laparoscopic-isthmocele-treatment-single-center-experience
#6
Michał Ciebiera, Magdalena Ciebiera, Magdalena Czekańska-Rawska, Grzegorz Jakiel
INTRODUCTION: A cesarean section is the most frequently performed surgery in modern obstetrics. In case of an incorrect wound healing process there is a risk of a persistent uterine wall defect. Nowadays, due to the high frequency of cesarean sections, obstetricians have to deal with the threat of uterine rupture due to pathological wound healing. It has been proven that isthmocele can cause abnormal uterine bleeding (AUB), pelvic pain (PP), and secondary infertility (SI), and can be a place of improper pregnancy placement...
2017: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
https://www.readbyqxmd.com/read/28444613/no-difference-in-congenital-anomalies-prevalence-irrespective-of-insemination-methods-and-freezing-procedure-cohort-study-over-fourteen-years-of-an-art-population-in-the-south-of-france
#7
Any Beltran Anzola, Vanessa Pauly, Debbie Montjean, Line Meddeb, Cendrine Geoffroy-Siraudin, Roland Sambuc, Pierre Boyer, Marie-José Gervoise-Boyer
PURPOSE: A retrospective cohort study was conducted to evaluate and compare the prevalence of congenital anomalies in babies and fetuses conceived after four procedures of assisted reproduction technologies (ART). METHODS: The prevalence of congenital anomalies was compared retrospectively between 2750 babies and fetuses conceived between 2001 and 2014 in vitro fertilization with standard insemination (IVF), IVF with intracytoplasmic sperm injection (ICSI), IVF with frozen embryo transfer (FET-IVF), and ICSI with frozen embryo transfer (FET-ICSI)...
July 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28333354/men-s-knowledge-attitudes-and-behaviours-relating-to-fertility
#8
REVIEW
Karin Hammarberg, Veronica Collins, Carol Holden, Kate Young, Robert McLachlan
BACKGROUND: The increasingly common practice in high-income countries to delay childbearing to the fourth and fifth decades of life increases the risk of involuntary childlessness or having fewer children than desired. Older age also increases the risk of age-related infertility, the need for ART to conceive, and obstetric and neonatal complications. Existing research relating to childbearing focusses almost exclusively on women, and in public discourse declining fertility rates are often assumed to be the result of women delaying childbearing to pursue other life goals such as a career and travel...
July 1, 2017: Human Reproduction Update
https://www.readbyqxmd.com/read/28303822/human-papillomavirus-and-chlamydia-trachomatis-infection-in-gyneco-obstetric-outpatients-from-a-mexican-hospital
#9
Laura Conde-Ferráez, Jorge Ramiro Carrillo Martíez, Guadalupe Ayora-Talavera, María Del Refugio González Losa
CONTEXT: Human papillomavirus (HPV) and Chlamydia trachomatis are the most frequent sexually transmitted infections, usually asymptomatic. Persistent infection with high-risk HPV types and other cofactors such as the concomitant infection with C. trachomatis can represent a higher risk to develop cervical lesions; therefore, screening with sensitive methods could aid to identify women at risk. AIMS: The aim is to determine the prevalence and concurrence of both infections, detected with in-house molecular methods, and to identify the risk factors associated to the infections in Mexican women...
January 2017: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28221188/treatment-of-cervical-intraepithelial-neoplasia-patients-preferences-for-surgery-or-immunotherapy-with-imiquimod
#10
Margot M Koeneman, Brigitte A Essers, Cornelis G Gerestein, Anna J M van de Sande, Rogier J N T M Litjens, Dieuwke Boskamp, Medi F J Goossens, Heleen J Beekhuizen, Roy F P M Kruitwagen, Arnold J Kruse, Carmen D Dirksen
OBJECTIVE: Imiquimod has been studied as a noninvasive pharmacological treatment alternative to large loop excision of the transformation zone (LLETZ) for high-grade cervical intraepithelial neoplasia (CIN), to prevent long-term obstetric complications from surgical treatment. This study aims to investigate womens' preferences for treatment of high-grade CIN with imiquimod or LLETZ. METHODS: A labeled discrete choice experiment was conducted among 100 women with abnormal cervical cytology in 5 hospitals in the Netherlands between March 2014 and December 2015...
February 17, 2017: Journal of Immunotherapy
https://www.readbyqxmd.com/read/28029396/standards-of-care-in-infertility-in-europe
#11
REVIEW
Christina I Messini, Alexandros Daponte, George Anifandis, Tahir Mahmood, Ioannis E Messinis
Evidence-based medicine is the principal approach to medical practice. There are several debatable issues in infertility, which require clarification. Over the past 20 years, reliable methodology has been developed for the management of infertile couples. This includes high quality diagnostic and therapeutic procedures, which are applied in highly specialised infertility centres. The European Board and College of Obstetrics and Gynaecology (EBCOG) has published Standards of Care for Women's Health in Europe, which should be the cornerstone for the clinicians and service providers in the European Union to establish common protocols within their centres...
October 20, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27450186/oocyte-or-embryo-donation-to-women-of-advanced-reproductive-age-an-ethics-committee-opinion
#12
(no author information available yet)
Advanced reproductive age (ARA) is a risk factor for female infertility, pregnancy loss, fetal anomalies, stillbirth, and obstetric complications. Oocyte donation reverses the age-related decline in implantation and birth rates of women in their 40s and 50s and restores pregnancy potential beyond menopause. However, obstetrical complications in older patients remain high, particularly related to operative delivery and hypertensive and cardiovascular risks. Physicians should perform a thorough medical evaluation designed to assess the physical fitness of a patient for pregnancy before deciding to attempt transfer of embryos to any woman of advanced reproductive age (>45 years)...
October 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27261985/osteopathic-manipulative-treatment-in-gynecology-and-obstetrics-a-systematic-review
#13
REVIEW
Nuria Ruffini, Giandomenico D'Alessandro, Lucia Cardinali, Franco Frondaroli, Francesco Cerritelli
OBJECTIVE: The aim of the review was to evaluate the effects of the osteopathic manipulative treatment (OMT) on women with gynaecological and obstetric disorders. MATERIALS AND METHODS: An extensive search from inception to April 2014 was conducted on MEDLINE, Embase, the Cochrane library using MeSH and free terms. Clinical studies investigating the effect of OMT in gynaecologic and obstetric conditions were included as well as unpublished works. Reviews and personal contributions were excluded...
June 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27172401/are-intracytoplasmic-sperm-injection-and-high-serum-estradiol-compounding-risk-factors-for-adverse-obstetric-outcomes-in-assisted-reproductive-technology
#14
Greene Donald Royster, Kavitha Krishnamoorthy, John M Csokmay, Belinda J Yauger, Rebecca J Chason, Alan H DeCherney, Erin F Wolff, Micah J Hill
OBJECTIVE: To evaluate whether intracytoplasmic sperm injection (ICSI) use and E2 on the final day of assisted reproductive technology (ART) stimulation are associated with adverse obstetric complications related to placentation. DESIGN: Retrospective cohort study. SETTING: Large private ART practice. PATIENT(S): A total of 383 women who underwent ART resulting in a singleton live birth. INTERVENTION(S): None...
August 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27083429/-risk-of-perinatal-complication-and-egg-donation-role-of-resorting-to-cross-border-care
#15
A Vincent-Rohfritsch, A Marszalek, P Santulli, V Gayet, C Chapron, F Goffinet, C Le Ray
OBJECTIVES: In France, egg donation is covered by Social insurance among women<43 years old. Because of shortage of egg donor, women aged 43 years or more cannot resort to egg donation in French infertility centers, leading them to turn to the foreign centers having practices different and less regulated than in France. We are thus brought to take care of the pregnancy and of the delivery of these women. Our objective was to estimate if the perinatal risks are more important after egg donation abroad than in case of egg donation in a French center...
October 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
https://www.readbyqxmd.com/read/26820772/subchorionic-hematomas-are-increased-in-early-pregnancy-in-women-taking-low-dose-aspirin
#16
Ashley Truong, M Mercedes Sayago, William H Kutteh, Raymond W Ke
OBJECTIVE: To determine the frequency of subchorionic hematomas (SCH) in first-trimester ultrasound examinations of patients with infertility and recurrent pregnancy loss (RPL) and in patients from a general obstetric population. To determine if the method of assisted reproduction utilized or the use of anticoagulants, such as heparin and aspirin (ASA), influenced frequency of SCH. DESIGN: Prospective, cohort study. SETTING: Fertility clinic and general obstetrics clinic...
May 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/26454266/surrogacy-outcomes-for-surrogate-mothers-children-and-the-resulting-families-a-systematic-review
#17
REVIEW
Viveca Söderström-Anttila, Ulla-Britt Wennerholm, Anne Loft, Anja Pinborg, Kristiina Aittomäki, Liv Bente Romundstad, Christina Bergh
BACKGROUND: Surrogacy is a highly debated method mainly used for treating women with infertility caused by uterine factors. This systematic review summarizes current levels of knowledge of the obstetric, medical and psychological outcomes for the surrogate mothers, the intended parents and children born as a result of surrogacy. METHODS: PubMed, Cochrane and Embase databases up to February 2015 were searched. Cohort studies and case series were included. Original studies published in English and the Scandinavian languages were included...
March 2016: Human Reproduction Update
https://www.readbyqxmd.com/read/26450684/adverse-obstetric-outcomes-in-pregnancies-resulting-from-oocyte-donation-a-retrospective-cohort-case-study-in-sweden
#18
Evangelia Elenis, Agneta Skoog Svanberg, Claudia Lampic, Alkistis Skalkidou, Helena Åkerud, Gunilla Sydsjö
BACKGROUND: Oocyte donation has been associated to gestational diabetes, hypertensive disorders, placental abnormalities, preterm delivery and increased rate of caesarean delivery while simultaneously being characterized by high rates of primiparity, advanced maternal age and multiple gestation constituting the individual risk of mode of conception difficult to assess. This study aims to explore obstetrical outcomes among relatively young women with optimal health status conceiving singletons with donated versus autologous oocytes (via IVF and spontaneously)...
2015: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/26395640/infertility-and-reproductive-disorders-impact-of-hormonal-and-inflammatory-mechanisms-on-pregnancy-outcome
#19
REVIEW
Silvia Vannuccini, Vicki L Clifton, Ian S Fraser, Hugh S Taylor, Hilary Critchley, Linda C Giudice, Felice Petraglia
BACKGROUND: Reproductive disorders and infertility are associated with the risk of obstetric complications and have a negative impact on pregnancy outcome. Affected patients often require assisted reproductive technologies (ART) to conceive, and advanced maternal age is a further confounding factor. The challenge is to dissect causation, correlation and confounders in determining how infertility and reproductive disorders individually or together predispose women to poor pregnancy outcomes...
January 2016: Human Reproduction Update
https://www.readbyqxmd.com/read/26085011/consanguineous-marriage-prepregnancy-maternal-characteristics-and-stillbirth-risk-a-population-based-case-control-study
#20
Siavash Maghsoudlou, Sven Cnattingius, Mohsen Aarabi, Scott M Montgomery, Shahriar Semnani, Olof Stephansson, Anna-Karin Wikström, Shahram Bahmanyar
INTRODUCTION: Consanguineous marriage is associated with increased risks for congenital anomalies, low birthweight, and other adverse perinatal outcomes. In this population-based, case-control study we investigated the association between consanguineous marriage (first-cousin marriage) and stillbirth risk, using prospectively collected information from prepregnancy visits. MATERIAL AND METHODS: From 2007 to 2009, we identified 283 stillbirths (cases) and 2088 randomly selected live control births through prepregnancy visits in rural Golestan, Iran...
October 2015: Acta Obstetricia et Gynecologica Scandinavica
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