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high risk obstetrics, infertility,

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Advanced reproductive age (ARA) is a risk factor for female infertility, pregnancy loss, fetal anomalies, stillbirth, and obstetric complications. Oocyte donation reverses the age-related decline in implantation and birth rates of women in their 40s and 50s and restores pregnancy potential beyond menopause. However, obstetrical complications in older patients remain high, particularly related to operative delivery and hypertensive and cardiovascular risks. Physicians should perform a thorough medical evaluation designed to assess the physical fitness of a patient for pregnancy before deciding to attempt transfer of embryos to any woman of advanced reproductive age (>45 years)...
October 2016: Fertility and Sterility
Nuria Ruffini, Giandomenico D'Alessandro, Lucia Cardinali, Franco Frondaroli, Francesco Cerritelli
OBJECTIVE: The aim of the review was to evaluate the effects of the osteopathic manipulative treatment (OMT) on women with gynaecological and obstetric disorders. MATERIALS AND METHODS: An extensive search from inception to April 2014 was conducted on MEDLINE, Embase, the Cochrane library using MeSH and free terms. Clinical studies investigating the effect of OMT in gynaecologic and obstetric conditions were included as well as unpublished works. Reviews and personal contributions were excluded...
June 2016: Complementary Therapies in Medicine
Greene Donald Royster, Kavitha Krishnamoorthy, John M Csokmay, Belinda J Yauger, Rebecca J Chason, Alan H DeCherney, Erin F Wolff, Micah J Hill
OBJECTIVE: To evaluate whether intracytoplasmic sperm injection (ICSI) use and E2 on the final day of assisted reproductive technology (ART) stimulation are associated with adverse obstetric complications related to placentation. DESIGN: Retrospective cohort study. SETTING: Large private ART practice. PATIENT(S): A total of 383 women who underwent ART resulting in a singleton live birth. INTERVENTION(S): None...
August 2016: Fertility and Sterility
A Vincent-Rohfritsch, A Marszalek, P Santulli, V Gayet, C Chapron, F Goffinet, C Le Ray
OBJECTIVES: In France, egg donation is covered by Social insurance among women<43 years old. Because of shortage of egg donor, women aged 43 years or more cannot resort to egg donation in French infertility centers, leading them to turn to the foreign centers having practices different and less regulated than in France. We are thus brought to take care of the pregnancy and of the delivery of these women. Our objective was to estimate if the perinatal risks are more important after egg donation abroad than in case of egg donation in a French center...
April 12, 2016: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
Ashley Truong, M Mercedes Sayago, William H Kutteh, Raymond W Ke
OBJECTIVE: To determine the frequency of subchorionic hematomas (SCH) in first-trimester ultrasound examinations of patients with infertility and recurrent pregnancy loss (RPL) and in patients from a general obstetric population. To determine if the method of assisted reproduction utilized or the use of anticoagulants, such as heparin and aspirin (ASA), influenced frequency of SCH. DESIGN: Prospective, cohort study. SETTING: Fertility clinic and general obstetrics clinic...
May 2016: Fertility and Sterility
Viveca Söderström-Anttila, Ulla-Britt Wennerholm, Anne Loft, Anja Pinborg, Kristiina Aittomäki, Liv Bente Romundstad, Christina Bergh
BACKGROUND: Surrogacy is a highly debated method mainly used for treating women with infertility caused by uterine factors. This systematic review summarizes current levels of knowledge of the obstetric, medical and psychological outcomes for the surrogate mothers, the intended parents and children born as a result of surrogacy. METHODS: PubMed, Cochrane and Embase databases up to February 2015 were searched. Cohort studies and case series were included. Original studies published in English and the Scandinavian languages were included...
March 2016: Human Reproduction Update
Evangelia Elenis, Agneta Skoog Svanberg, Claudia Lampic, Alkistis Skalkidou, Helena Åkerud, Gunilla Sydsjö
BACKGROUND: Oocyte donation has been associated to gestational diabetes, hypertensive disorders, placental abnormalities, preterm delivery and increased rate of caesarean delivery while simultaneously being characterized by high rates of primiparity, advanced maternal age and multiple gestation constituting the individual risk of mode of conception difficult to assess. This study aims to explore obstetrical outcomes among relatively young women with optimal health status conceiving singletons with donated versus autologous oocytes (via IVF and spontaneously)...
2015: BMC Pregnancy and Childbirth
Silvia Vannuccini, Vicki L Clifton, Ian S Fraser, Hugh S Taylor, Hilary Critchley, Linda C Giudice, Felice Petraglia
BACKGROUND: Reproductive disorders and infertility are associated with the risk of obstetric complications and have a negative impact on pregnancy outcome. Affected patients often require assisted reproductive technologies (ART) to conceive, and advanced maternal age is a further confounding factor. The challenge is to dissect causation, correlation and confounders in determining how infertility and reproductive disorders individually or together predispose women to poor pregnancy outcomes...
January 2016: Human Reproduction Update
Siavash Maghsoudlou, Sven Cnattingius, Mohsen Aarabi, Scott M Montgomery, Shahriar Semnani, Olof Stephansson, Anna-Karin Wikström, Shahram Bahmanyar
INTRODUCTION: Consanguineous marriage is associated with increased risks for congenital anomalies, low birthweight, and other adverse perinatal outcomes. In this population-based, case-control study we investigated the association between consanguineous marriage (first-cousin marriage) and stillbirth risk, using prospectively collected information from prepregnancy visits. MATERIAL AND METHODS: From 2007 to 2009, we identified 283 stillbirths (cases) and 2088 randomly selected live control births through prepregnancy visits in rural Golestan, Iran...
October 2015: Acta Obstetricia et Gynecologica Scandinavica
Mark V Sauer
Advanced age is a risk factor for female infertility, pregnancy loss, fetal anomalies, stillbirth, and obstetric complications. These concerns are based on centuries-old observations, yet women are delaying childbearing to pursue educational and career goals in greater numbers than ever before. As a result, reproductive medicine specialists are treating more patients with age-related infertility and recurrent pregnancy loss, while obstetricians are faced with managing pregnancies often complicated by both age and comorbidities...
May 2015: Fertility and Sterility
Gamal A Kassem
AIM: The aim of this work was to assess scientific research of master's and doctoral theses and essays in the Department of Obstetrics and Gynecology, Zagazig University, Egypt. MATERIALS AND METHODS: All master's and doctoral theses and essays since the foundation of Department of Obstetrics and Gynecology, Zagazig University, Egypt, in 1975 till end of 2012 were reviewed. RESULTS: A total of 703 theses and essays were reviewed. The important topics in the specialty of obstetrics and gynecology were covered and updated...
2015: International Journal of Women's Health
Waleed El-Khayat, Mostafa Elsadek
OBJECTIVE: To evaluate the role of calcium infusion as a preventive strategy of ovarian hyperstimulation syndrome (OHSS) in women at high risk in in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) treatment cycles. DESIGN: Double-blinded randomized controlled trial. SETTING: University hospital department of obstetrics and gynecology and private IVF center. PATIENT(S): Two hundred women at risk to develop OHSS undergoing IVF/ICSI treatment cycle...
January 2015: Fertility and Sterility
Ma José Fernandez Varelo, Juan Miguel Martínez Galiano, Antonio Herrera Gómez
INTRODUCTION: The global epidemic of overweight and obesity is becoming, as its growth into a major public health problem in many parts of the world affects about half the general population and is therefore a problem common among fertile. EXPOSURE: Obesity and overweight are common conditions that have implications not only for overall health, but also largely on reproductive health. A high prevalence of obese women in the sterile population and numerous studies have highlighted the link between obesity and infertility...
December 2011: Revista de Enfermería
C Deneux-Tharaux, M-P Bonnet, J Tort
OBJECTIVES: To synthesize the available evidence regarding the incidence, causes, risk factors of post-partum haemorrhage (PPH) and the associated maternal morbidity. METHODS: Consultation of the Medline database and of national reports on maternal mortality. RESULTS: PPH is defined as a post-partum blood loss≥500mL, and severe PPH as a post-partum blood loss≥1000mL, whatever the delivery route. In population-based studies, the incidence of PPH is around 5% of deliveries when blood loss is not precisely assessed and around 10% when it is...
December 2014: Journal de Gynécologie, Obstétrique et Biologie de la Reproduction
George Pados, Dimitrios Tsolakidis, Dimitrios Athanatos, Konstadinos Almaloglou, Nikos Nikolaidis, Basil Tarlatzis
OBJECTIVE: To present the reproductive and obstetric outcome after laparoscopic excision of functional, non-communicating broadly attached rudimentary horn. STUDY DESIGN: As a part of a retrospective study performed over the past 21 years to determine the reproductive and obstetric outcome after laparoscopic treatment for symptomatic non-communicating rudimentary horn, we identified seven women who became pregnant after laparoscopic removal of the broadly attached rudimentary horn...
November 2014: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Kozue Asato, Keiko Mekaru, Chiaki Heshiki, Hitoshi Sugiyama, Tadatugu Kinjyo, Hitoshi Masamoto, Yoichi Aoki
OBJECTIVE: Obstetric complications occur more frequently in pregnancies after in vitro fertilization (IVF). We attempted to determine the correlation between subchorionic hematoma and IVF pregnancies. STUDY DESIGN: We analyzed 194 pregnancies achieved by infertility treatment between January 2008 and February 2012 at our hospital. Among these, 67 were achieved by IVF and 127 by non-IVF approaches. We compared the frequency of subchorionic hematoma between the groups and examined the risk factors for subchorionic hematoma in the IVF group...
October 2014: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Rose L Molina, Khady Diouf, Nawal M Nour
Tuberculosis (TB) infection poses substantial challenges for obstetricians and gynecologists globally, as gynecologic involvement may cause infertility, irregular bleeding, and pelvic pain. If TB-infected women are able to conceive, obstetric complications include intrauterine growth restriction and, more rarely, congenital transmission. Appropriate screening for high-risk populations is crucial for diagnosis and treatment of latent and active TB infection, which may prevent reproductive sequelae for individual patients and, eventually, contribute to complete eradication of the disease...
2013: Reviews in Obstetrics and Gynecology
Simon Fishel, Rashmi Patel, Alison Lytollis, Jeanette Robinson, Mary Smedley, Paula Smith, Craig Cameron, Simon Thornton, Ken Dowell, Glenn Atkinson, Adel Shaker, Philip Lowe, Rahnuma Kazem, Sandra Brett, Anna Fox
Thrombophilia and impaired placental vasculature are a major cause of adverse pregnancy outcome. In 2007, a new hereditary factor for obstetric complications and recurrent pregnancy loss (RPL) was identified as a sequence variation in the core promoter of the annexin A5 gene, ANXA5, called the M2 haplotype. M2 carriership has been demonstrated in couples with recurrent miscarriage and its origin is embryonic rather than specifically maternal, confirmed by subsequent papers. The M2 haplotype is the first report of a hereditary factor related to pregnancy pathology caused by embryonic-induced anticoagulation...
July 2014: Reproductive Biomedicine Online
Jaime M Knopman, Lewis C Krey, Cheongeun Oh, Jennifer Lee, Caroline McCaffrey, Nicole Noyes
OBJECTIVE: To identify the incidence, risk factors, and obstetric/perinatal outcomes associated with monozygotic twins (MZTs) after IVF. DESIGN: Nested case-control. SETTING: University-based center. PATIENT(S): The IVF cycles eventuating in pregnancy from 2000-2009. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): The MZT incidence, chorionicity/zygosity, pregnancy/neonatal outcome...
July 2014: Fertility and Sterility
I Gurol-Urganci, D A Cromwell, T A Mahmood, J H van der Meulen, A Templeton
STUDY QUESTION: Is there an association between Caesarean section and subsequent fertility? SUMMARY ANSWER: There is no or only a slight effect of Caesarean section on future fertility. WHAT IS KNOWN ALREADY: Previous studies have reported that delivery by a Caesarean section is associated with fewer subsequent pregnancies and longer inter-pregnancy intervals. The interpretation of these findings is difficult because of significant weaknesses in study designs and analytical methods, notably the potential effect of the indication for Caesarean section on subsequent delivery...
June 2014: Human Reproduction
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