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Gallbladder polyps

Ming-Jie Zhang, Qiang Yan, Guo-Lei Zhang, Si-Yu Zhou, Wen-Bin Yuan, Hua-Ping Shen
BACKGROUND AND OBJECTIVES: Patients with previous gastrectomy have an increased incidence of gallstones and gallbladder morbidity requiring surgery. We investigated the possible risk factors that contribute to severe gallbladder disease in patients with previous gastrectomy and the role of laparoscopic cholecystectomy (LC) in the treatment of these patients. METHODS: In this retrospective study, we reviewed a database of patients who underwent LC in our hospital during the period January 1, 2010, through May 1, 2015...
October 2016: JSLS: Journal of the Society of Laparoendoscopic Surgeons
Jeong Sub Lee, Jung Hoon Kim, Yong Jae Kim, Ji Kon Ryu, Yong-Tae Kim, Jae Young Lee, Joon Koo Han
PURPOSE: To compare the diagnostic accuracy of transabdominal high-resolution ultrasound (HRUS) for staging gallbladder cancer and differential diagnosis of neoplastic polyps compared with endoscopic ultrasound (EUS) and pathology. MATERIALS AND METHODS: Among 125 patients who underwent both HRUS and EUS, we included 29 pathologically proven cancers (T1 = 7, T2 = 19, T3 = 3) including 15 polypoid cancers and 50 surgically proven polyps (neoplastic = 30, non-neoplastic = 20)...
November 10, 2016: European Radiology
Krashna Patel, Khaled Dajani, Satheesh Iype, Nikolaos A Chatzizacharias, Saranya Vickramarajah, Prateush Singh, Susan Davies, Rebecca Brais, Siong S Liau, Simon Harper, Asif Jah, Raaj K Praseedom, Emmanuel L Huguet
AIM: To analyse the range of histopathology detected in the largest published United Kingdom series of cholecystectomy specimens and to evaluate the rational for selective histopathological analysis. METHODS: Incidental gallbladder malignancy is rare in the United Kingdom with recent literature supporting selective histological assessment of gallbladders after routine cholecystectomy. All cholecystectomy gallbladder specimens examined by the histopathology department at our hospital during a five year period between March 2008 and March 2013 were retrospectively analysed...
October 27, 2016: World Journal of Gastrointestinal Surgery
R Arcega, J X Wu, S Magaki, T R Donahue, H L Wang
We report a case of two peculiar gallbladder polyps in a sixty-four year old male who presented with symptomatic cholelithiasis. Cholecystectomy was performed, which revealed two polyps measuring 0.6 cm and 1.9 cm, located in the body of the gallbladder. Microscopic examination of the polyps showed composite mesenchymal lesions with vascular proliferation of small-to-medium sized arterioles, myoid stroma, and lipomatous periphery. The myoid component was characterized by wisps of bland smooth muscle fibers loosely separated by proteinaceous and focally myxoid matrix...
July 2016: Acta Gastro-enterologica Belgica
Hai-da Shi, Xian-Jie Shi, Shao-Cheng Lv, Huan-Xian Ma, Yu-Rong Liang, Lin Zhou, Yong Shi
OBJECTIVE: To summarize the 23-year experience of laparoscopic biliary surgery in General Hospital of PLA and evaluate the application of laparoscopic surgery in the treatment of biliary diseases. METHODS: We retrospectively analyzed the clinical data of 11 419 consecutive patients with biliary diseases undergoing laparoscopic surgery from April, 1992 and December, 2014. The disease spectrum was compared between patients treated before December 31, 2003 and those treated after the time point...
October 20, 2016: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
Luis Manuel Souza-Gallardo, Mauricio de la Fuente-Lira, Roberto Galaso-Trujillo, José Luis Martínez-Ordaz
BACKGROUND: Tumour markers are substances produced by the tumour itself, or by the host in response to a tumour. These markers could be measured either in the blood or in body secretions. One of the most common tumour markers used in gastrointestinal diseases is Ca 19-9. It is the marker most used for pancreatic cancer, but can be elevated in many benign processes. Thus, it is not a specific marker. CLINICAL CASE: The case is presented of a male patient with 4 years of moderate abdominal pain, weight loss, and persistent elevation of Ca 19-9...
September 5, 2016: Cirugia y Cirujanos
Kyo-Sang Yoo, Ho Soon Choi, Dae Won Jun, Hang Lak Lee, Oh Young Lee, Byung Chul Yoon, Kyeong Geun Lee, Seung Sam Paik, Yong Seok Kim, Jin Lee
BACKGROUND/AIMS: Gallstone pathogenesis is linked to mucin hypersecretion and bacterial infection. Several mucin genes have been identified in gallbladder epithelial cells (GBECs). We investigated MUC expression in cholesterol-associated gallbladder disease and evaluated the relationship between mucin and bacterial infection. METHODS: The present study involved 20 patients with cholesterol stones with cholecystitis, five with cholesterol stones with cholesterolosis, six with cholesterol polyps, two with gallbladder cancer, and six controls...
September 15, 2016: Gut and Liver
Jun Suh Lee, Tae Ho Hong
INTRODUCTION: An important issue in laparoscopic surgery is initial peritoneal access. An intraumbilical (IU) incision may be easier and faster to place, but due to concerns about wound complications, the periumbilical (PU) incision is still often used. A prospective randomized controlled study was performed to investigate the outcomes of the IU incision and PU incision in laparoscopic cholecystectomy. METHODS: Study subjects were patients who received laparoscopic cholecystectomy for acute or chronic cholecystitis, gallbladder polyp or adenomyomatosis, or porcelain gallbladder from June 2014 to January 2015...
September 2016: International Journal of Surgery
Mohamed Elmasry, Don Lindop, Declan F J Dunne, Hassan Malik, Graeme J Poston, Stephen W Fenwick
INTRODUCTION: Gallbladder polyps (GBPs) are a common incidental finding on ultrasound (US) examination. The malignant potential of GBPs is debated, and there is limited guidance on surveillance. This systematic review sought to assess the natural history of ultrasonographically diagnosed GBPs and their malignant potential. METHODS: The keywords: "Gallbladder" AND ("polyp" OR "polypoid lesion") were used to conduct a search in four reference libraries to identify studies which examined the natural history of GBPs diagnosed by US...
September 2016: International Journal of Surgery
Konstantinos Stergios, Christos Damaskos, Maximos Frountzas, Nikolaos Nikiteas, Olutunde Lalude
OBJECTIVE: The purpose of the present systematic review is to identify whether an association between gallbladder polyps and colorectal adenoma or neoplasia exists. DATA SOURCES: We conducted a systematic review searching the Medline (1966-2016), Scopus (2004-2016), (2008-2016) and Cochrane Central Register of Controlled Trials CENTRAL (1999-2016) databases together with reference lists from included studies. STUDY ELIGIBILITY CRITERIA: All prospective and retrospective observational cohort studies were included...
September 2016: International Journal of Surgery
Michihiro Yamamoto, Masazumi Zaima, Yuya Kida, Hidekazu Yamamoto, Hideki Harada, Junichiro Kawamura, Masahiro Yamada, Tekefumi Yazawa
BACKGROUND: Generally, single-incision laparoscopic cholecystectomy (SILC) requires the use of articulating devices or additional trocars because of the technical difficulties caused by the lack of ergonomics. We developed a novel procedure comprising mainly two simple ideas, "the teres hanging technique combined with fundus-first, dome-down separation," which mainly uses conventional rigid laparoscopic instruments. In this study, we demonstrated our technique and retrospectively evaluated the clinical outcomes...
July 7, 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
Ali Asghar Darzi, Alieh Nikmanesh, Farhad Bagherian
BACKGROUND: Laparoscopic cholecystectomy (LC) is one of the most common surgeries in laparoscopic surgery. Although, it is believed that LC has low-risk for post-operative infectious complications, the use of a prophylactic antibiotic is still controversial in elective LC. OBJECTIVE: To determine the impact of prophylactic antibiotics on postoperative infection complications in elective laparoscopic cholecystectomy. METHODS: In this double-blind, placebo-controlled, randomized, clinical trial, patients who were candidates for elective LC, from March 2012 to 2015, in four hospitals in Babol, Iran, were studied...
May 2016: Electronic Physician
W W Zhang, S C Lü, X J Shi, W Q Gu, Y L Chen, W Z Zhang, K Jiang, J Wang, X Q Huang, H T Xia, Z Q Huang, S C Lu
OBJECTIVE: To explore the changing trend and clinical significance of disease spectrum of biliary surgery among 30 years in PLA General Hospital. METHODS: We retrospectively analyzed the clinical data of 21 189 consecutive patients with biliary diseases in PLA General Hospital between January 1985 and December 2014 according to the inclusion criteria. Taking 5 years as a research group, all patients were divided into 6 groups, and then the 30 years of the disease spectrum of biliary surgery was described...
June 28, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Diane F van Rappard, Marianna Bugiani, Jaap J Boelens, Alida F W van der Steeg, Freek Daams, Tim G J de Meij, Martine M A C van Doorn, Peter M van Hasselt, Dirk J Gouma, Jonathan I M L Verbeke, Carla E M Hollak, Wim van Hecke, Gajja S Salomons, Marjo S van der Knaap, Nicole I Wolf
OBJECTIVES: To assess frequency of gallbladder polyposis and carcinoma in metachromatic leukodystrophy (MLD). METHODS: We evaluated 34 patients with MLD (average age 16.7 years, age range 2-39 years) screened for gallbladder abnormalities by ultrasound. In the case of cholecystectomy, findings at pathology were reviewed. RESULTS: Only 8 of 34 patients (23%) had a normal gallbladder at ultrasound. Gallbladder polyps were visible in 8 patients (23%)...
July 5, 2016: Neurology
Daniel Mønsted Shabanzadeh, Lars Tue Sørensen, Torben Jørgensen
OBJECTIVE: Only few determinants of gallstone formation have been identified in cohort studies. The aim was to identify further determinants for gallstones in a Danish cohort and to perform a meta-analysis of results from existing cohorts. MATERIAL AND METHODS: Data from a cohort study was used. Gallstone incidence was assessed through repeated ultrasound examinations. Body mass index (BMI), blood pressure, self-rated health, lifestyle variables, blood lipids, and use of female sex hormones were measured at the baseline examination...
October 2016: Scandinavian Journal of Gastroenterology
Kiyomi Tanno, Seiji Bito, Yoh Isobe, Yasuo Takagi
BACKGROUND AND PURPOSE: In Japanese health care, no current index measures patient satisfaction with decision making during the treatment process. Our research aimed to test a Japanese version of the Decision Regret Scale (DRS) for this purpose. METHODS: We distributed a Japanese version of the DRS twice, 3 weeks apart, to 80 postoperative patients younger than the age of 85 years with inguinal hernias, cholelithiasis, cholecystitis, and gallbladder polyps. RESULTS: The reliability (α = ...
2016: Journal of Nursing Measurement
Wuttiporn Manatsathit, Pornchai Leelasincharoen, Hussein Al-Hamid, Susanna Szpunar, Abdelkader Hawasli
INTRODUCTION: Gallstones commonly develop after Roux-en-Y gastric bypass and other bariatric surgery; however, incidence of gallstone development after SG has not been adequately studied. METHODS: We conducted a retrospective cohort study of patients who underwent SG at two institutions from January 1, 2011 to December 31, 2012. Patients with previous cholecystectomy, preexisting gallstones, gallbladder polyps, or the absence of preoperative abdominal imaging were excluded...
April 5, 2016: International Journal of Surgery
J F Gerstenmaier, K N Hoang, R N Gibson
With its excellent contrast and spatial resolution, and the ability to image in real-time, ultrasound is the main imaging modality for assessing the gallbladder (GB). The application of contrast-enhanced ultrasound (CEUS) of the GB is now increasingly recognized as a useful addition to ultrasound and other cross-sectional imaging in the assessment of neoplastic and non-neoplastic GB disease. With the ability to image microcirculation and optimal contrast resolution, CEUS allows high-quality delineation in real-time, allowing for increased diagnostic confidence...
August 2016: Abdominal Radiology
Guang Yang, Haixia Qin, Anwar Raza, George W Saukel, Naveenraj Solomon, Marcos Michelotti, Ravi Raghavan
Adenomas of the gallbladder are uncommon benign epithelial neoplasms. Rarely, they can give rise to gallbladder cancer, which is the most common malignancy of the biliary tract, carrying a poor prognosis and decreased survival. Here we report the case histories of two patients, 40-year-old and 53-year-old males who presented with >1 cm gallbladder polyps, which were detected and confirmed using various imaging studies. Cholecystectomy was performed on both patients and the subsequent pathologic exam revealed 1...
April 2016: Journal of Gastrointestinal Oncology
B B Shrestha, M Karmacharya, B B Gharti, B Timilsina, P Ghimire
INTRODUCTION: Laparoscopic cholecystectomy (LC) is elective surgical procedure for uncomplicated gallstone disease and gallbladder polyp. The objective of this study was to assess the efficacy of Dexamethasone and Pheniramine hydrogen maleate on reducing stress response and pain after surgery in patients undergoing laparoscopic cholecystectomy. METHODS: After obtaining approval from the institutional ethics committee and written informed consent, 120 patients undergoing elective laparoscopic cholecystectomy were enrolled in the study from Sep 2103 to Aug 2014 at Department of Surgery, Manipal College of Medical Sciences, Pokhara, Nepal...
July 2014: JNMA; Journal of the Nepal Medical Association
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