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https://www.readbyqxmd.com/read/27909501/-two-for-the-price-of-one-a-single-lead-implantable-cardioverter-defibrillator-system-with-a-floating-atrial-dipole
#1
REVIEW
Nicole E Worden Md, Musab Alqasrawi Md, Siva M Krothapalli Md, Alexander Mazur Md
In patients known to be a high risk for sudden cardiac arrest, implantable cardioverter defibrillators (ICD) are a proven therapy to reduce risk of death. However, in patients without conventional indications for pacing, the optimal strategy for type of device, dual- versus single-chamber, remains debatable. The benefit of prophylactic pacing in this category of patients has never been documented. Although available atrial electrograms in a dual chamber system improve interpretation of stored arrhythmia events, allow monitoring of atrial fibrillation and may potentially reduce the risk of inappropriate shocks by enhancing automated arrhythmia discrimination, the use of dual-chamber ICDs has a number of disadvantages...
April 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27888595/quality-of-life-in-medical-students-with-internet-addiction
#2
Farzad Fatehi, Alireza Monajemi, Anahita Sadeghi, Rita Mojtahedzadeh, Azim Mirzazadeh
The widespread use of internet has caused new psychological, social, and educational problems for the students. The aim of this study was to examine the quality of life in medical students who suffer from internet addiction. This cross-sectional survey was carried out in Tehran University of Medical Sciences, and a total of 174 fourth-to seventh-year undergraduate medical students were enrolled. The quality of life was assessed by WHOQOL-BREF questionnaire which covers four domains of physical health, psychological, social relationships, and the environment...
October 2016: Acta Medica Iranica
https://www.readbyqxmd.com/read/27882604/the-dog-bone-technique-a-novel-easy-and-safe-catheter-maneuver-for-aortic-arch-and-coarctation-stenting
#3
Marinos Kantzis, Anja Lehner, Kai Thorsten Laser, Anca Racolta, Radka Vcasna, Marcus Fischer, Deniz Kececioglu, Nikolaus A Haas
BACKGROUND: Various techniques are described to facilitate stable stent implantation in aortic arch stenosis or coarctation. We describe an alternative technique, which due to its unique appearance during stent implantation, we have named "Dog Bone Technique" (DBT). TECHNIQUE: The stent/balloon assembly is placed across the stenosis, the long sheath is retrieved to uncover the distal 20-50% of the stent. The balloon is inflated with the pressure inflator just to expand slightly the stent...
November 24, 2016: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/27866141/transapical-aortic-stenting-an-initial-case-series
#4
Tamer G Ghazy, Ahmed S Ouda, Ahmed M Mashhour, Manuel Wilbring, Klaus Matschke, Utz W Kappert
AIMS: The standard approach for thoracic endovascular aortic repair (TEVAR) is transfemoral; however, calcifications and tortuosity of the access vessels might be so extensive as to increase the operative risk markedly or preclude the procedure. This study evaluates the transapical approach as an alternative route for TEVAR in such patients. METHODS AND RESULTS: From June 2011 to July 2013, the institution's interdisciplinary board for aortic diseases initially denied TEVAR for eight patients with thoracic aortic pathology due to extensive calcification and tortuosity of the distal vessels...
November 20, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27865198/a-propensity-matched-case-control-study-comparing-efficacy-safety-and-costs-of-the-subcutaneous-vs-transvenous-implantable-cardioverter-defibrillator
#5
S Honarbakhsh, R Providencia, N Srinivasan, S Ahsan, M Lowe, E Rowland, R J Hunter, M Finlay, O Segal, M J Earley, A Chow, R J Schilling, P D Lambiase
BACKGROUND: Subcutaneous implantable cardioverter defibrillators (S-ICD) have become more widely available. However, comparisons with conventional transvenous ICDs (TV-ICD) are scarce. METHODS: We conducted a propensity matched case-control study including all patients that underwent S-ICD implantation over a five-year period in a single tertiary centre. Controls consisted of all TV-ICD implant patients over a contemporary time period excluding those with pacing indication, biventricular pacemakers and those with sustained monomorphic ventricular tachycardia requiring anti-tachycardia pacing...
November 7, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27864594/morphologic-classification-of-the-right-auricule-on-256-slice-computed-tomography
#6
Cai-Ying Li, Bu-Lang Gao, Tong Pan, Cheng Xiang, Xiao-Wei Liu, Hai-Qing Yang, Lan-Ying Yi, Qi-Bin Liao
PURPOSE: To investigate the shape of right auricule on 256-slice computed tomography (CT). MATERIALS AND METHODS: Five hundred people (250 men, age range 16-84 years) who had cardiac multidetector CT angiography were recruited in this study. All patients had normal sinus rhythm with normal blood pressure (<140/90 mmHg for systolic/diastolic pressure). The morphology of the right auricule was studied and compared after reconstruction of the raw images. RESULTS: All patients successfully had cardiac CT angiography (100%), and the right auricule morphology was divided into five types and nine subtypes, including Type I of triangular shape (Ia and Ib), Type II of M shape (IIa and IIb), Type III of L shape (IIIa and IIIb), Type IV of reverse L shape (IVa and IVb), and Type V of balanced shape...
November 18, 2016: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/27862860/incidence-and-predictors-of-permanent-pacemaker-implantation-following-treatment-with-the-repositionable-lotus%C3%A2-transcatheter-aortic-valve
#7
Sarah Zaman, Liam McCormick, Robert Gooley, Hashrul Rashid, Satish Ramkumar, Damon Jackson, Samuel Hui, Ian T Meredith
OBJECTIVES: To determine the incidence and predictors of permanent pacemaker (PPM) requirement following transcatheter aortic valve replacement (TAVR) with the mechanically expanded Lotus(TM) Valve System (Boston Scientific). BACKGROUND: Pacemaker implantation is the most common complication following TAVR. Predictors of pacing following TAVR with the Lotus valve have not been systematically assessed. METHODS: Consecutive patients with severe aortic stenosis who underwent Lotus valve implantation were prospectively recruited at a single-centre...
November 12, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27861115/leadless-cardiac-pacing-what-primary-care-providers-and-non-ep-cardiologists-should-know
#8
REVIEW
Erich L Kiehl, Daniel J Cantillon
Over the last 50 years, the use of transvenous pacemakers has been constrained by long-term complications that affect more than 1 in 10 patients, largely attributable to the endovascular leads and surgical pocket. Leadless cardiac pacing involves a self-contained pacemaker deployed directly into the heart without a lead or incisional access. The procedure has shown promise, eliminating pocket-related complications. Other advantages include postprocedural shoulder mobility and the ability to drive, shower, and bathe...
November 2016: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/27855290/transcatheter-leadless-cardiac-pacing-the-new-alternative-solution
#9
Antoine Da Costa, Amandine Axiotis, Cécile Romeyer-Bouchard, Loucif Abdellaoui, Zahi Afif, Jean Baptiste Guichard, Antoine Gerbay, Karl Isaaz
INTRODUCTION: A lack of information about the feasibility and safety of leadless pacemaker (LPMs) exists in a fragile population of patients with limited venous anatomy access or conventional pacemaker (PM) contraindication. Accordingly, the goal of this prospective observational study was to report our experience with this new leadless technology in a subset of patients with contraindication or limited venous access. METHODS AND RESULTS: Between May 2015 and July 2016, 14 patients were consecutively included...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27848007/transcatheter-tricuspid-valve-in-valve-replacement-one-year-results-alternative-to-surgery-in-high-risk-patients
#10
João Mesquita, Rui Campante Teles, José Pedro Neves, João Abecasis, Pedro Carmo, João Brito, Miguel Abecasis, Manuel Sousa Almeida, Marisa Trabulo, Regina Ribeiras, Ricardo Seabra-Gomes, Miguel Mendes
Although rheumatic heart disease is becoming uncommon in industrialized countries, its global burden is still significant. We report the case of a 70-year-old male with rheumatic heart disease, who underwent 4 previous heart valve replacement surgeries, and presented to our hospital with refractory heart failure (NYHA functional class IV) due to severe stenosis of a previously implanted tricuspid bioprosthesis. The Heart Team deemed the patient as inoperable/high-risk for surgery. As an alternative, a transcatheter tricuspid valve-in-valve replacement was decided upon and later executed through the right femoral vein, with the insertion of an Edwards SAPIEN XT 29 no...
November 15, 2016: Heart and Vessels
https://www.readbyqxmd.com/read/27845280/-vaspin-levels-and-carbohydrate-status-in-young-patients-with-hypertension-and-obesity
#11
V Zlatkina
The current pace of growth in body weight and complications in children and patients of the young age is a serious problem. The aim of the work was to determine the vaspin concentration depending on the presence of obesity in patients of the young age with arterial hypertension and the study of its relationship with carbohydrate metabolism. The progression of obesity and hypertension is accompanied by increase of insulin resistance. The increase in the blood concentration of vaspin is observed in patients with hypertension and normal body weight...
October 2016: Georgian Medical News
https://www.readbyqxmd.com/read/27843046/impact-of-renal-function-impairment-assessed-by-ckdepi-estimated-glomerular-filtration-rate-on-early-and-late-outcomes-after-coronary-artery-bypass-grafting
#12
Sandro Gelsomino, Stefano Del Pace, Orlando Parise, Sabina Caciolli, Francesco Matteucci, Giuseppe Fradella, Massimo Bonacchi, Simona Fusco, Fabiana Lucà, Niccoló Marchionni
BACKGROUND: We explore the association between short- and long- term adverse outcomes following coronary artery bypass grafting (CABG) and the degree of preoperative renal dysfunction classified on glomerular fraction estimated with Chronic Kidney Disease-Epidemiology Collaboration equation (eGFRCKD-EPI). We also try to identify cut-off values of eGFRCKD-EPI able to predict post-CABG unfavorable events and assess whether a reclassification with new thresholds is necessary. METHODS: One-thousand-one-hundred-eighty-six consecutive patients undergoing CABG between 2005 and 2014 were categorized in 4 groups according to the eGFRCKD-EPI: Group 1 (≥60ml/min/1...
October 24, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27815543/genetic-dissection-of-cancer-development-therapy-response-and-resistance-in-mouse-models-of-breast-cancer
#13
Stefano Annunziato, Marco Barazas, Sven Rottenberg, Jos Jonkers
The cancer genomics revolution has rapidly expanded the inventory of somatic mutations characterizing human malignancies, highlighting a previously underappreciated extent of molecular variability between and within patients. Also in breast cancer, the most commonly diagnosed malignancy in women, this heterogeneity complicates the understanding of the stepwise sequence of pathogenic events and the design of effective and long-lasting target therapies. To disentangle this complexity and pinpoint which molecular perturbations are crucial to hijack the cellular machinery and lead to tumorigenesis and drug resistance, functional studies are needed in model systems that faithfully and comprehensively recapitulate all the salient aspects of their cognate human counterparts...
November 4, 2016: Cold Spring Harbor Symposia on Quantitative Biology
https://www.readbyqxmd.com/read/27815374/treatment-with-tpa-in-the-golden-hour-and-the-shape-of-the-4-5-hour-time-benefit-curve-in-the-national-us-get-with-the-guidelines-stroke-population
#14
Joon-Tae Kim, Gregg C Fonarow, Eric E Smith, Mathew J Reeves, Digvijaya D Navalkele, James C Grotta, Maria V Grau-Sepulveda, Adrian F Hernandez, Eric D Peterson, Lee H Schwamm, Jeffrey L Saver
BACKGROUND: -Earlier tissue plasminogen activator (tPA) treatment improves ischemic stroke outcome, but aspects of the time-benefit relationship still not well delineated are: 1) the degree of additional benefit accrued with treatment in the first 60 minutes after onset, and 2) the shape of the time-benefit curve through 4.5 hours. METHODS: -We analyzed acute ischemic stroke patients treated with intravenous tPA within 4.5 hours of onset from the Get With The Guidelines-Stroke US national program...
November 4, 2016: Circulation
https://www.readbyqxmd.com/read/27810043/long-term-clinical-outcomes-of-subcutaneous-versus-transvenous-implantable-defibrillator-therapy
#15
Tom F Brouwer, Dilek Yilmaz, Robert Lindeboom, Maurits S Buiten, Louise R A Olde Nordkamp, Martin J Schalij, Arthur A Wilde, Lieselot van Erven, Reinoud E Knops
BACKGROUND: Transvenous implantable cardioverter-defibrillators (TV-ICDs) improve survival in patients at risk for sudden cardiac death, but complications remain an important drawback. The subcutaneous ICD (S-ICD) was developed to overcome lead-related complications. Comparison of clinical outcomes of both device types in previous studies was hampered by dissimilar patient characteristics. OBJECTIVES: This retrospective study compares long-term clinical outcomes of S-ICD and TV-ICD therapy in a propensity-matched cohort...
November 8, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27803120/cardiovascular-autonomic-neuropathy-and-cardiovascular-outcomes-in-the-diabetes-control-and-complications-trial-epidemiology-of-diabetes-interventions-and-complications-dcct-edic-study
#16
Rodica Pop-Busui, Barbara H Braffett, Bernie Zinman, Catherine Martin, Neil H White, William H Herman, Saul Genuth, Rose Gubitosi-Klug
OBJECTIVE: To examine whether cardiovascular autonomic neuropathy (CAN) is an independent risk factor of cardiovascular disease (CVD) events during DCCT/EDIC. RESEARCH DESIGN AND METHODS: Standardized cardiovascular autonomic reflex tests (R-R response to paced breathing, Valsalva maneuver, postural changes in blood pressure) were performed at DCCT baseline, every 2 years throughout DCCT, and at two time points in EDIC. CVD events were ascertained throughout the study and adjudicated by a review committee...
November 1, 2016: Diabetes Care
https://www.readbyqxmd.com/read/27799257/defibrillators-selecting-the-right-device-for-the-right-patient
#17
Sana M Al-Khatib, Paul Friedman, Kenneth A Ellenbogen
Advances in the field of defibrillation have brought to practice different types of devices that include the transvenous implantable cardioverter-defibrillator (ICD) with or without cardiac resynchronization therapy, the subcutaneous ICD (S-ICD), and the wearable cardioverter-defibrillator. To ensure optimal use of these devices and to achieve best patient outcomes, clinicians need to understand how these devices work, learn the characteristics of patients who qualify them for one type of device versus another, and recognize the remaining gaps in knowledge surrounding these devices...
November 1, 2016: Circulation
https://www.readbyqxmd.com/read/27793212/the-newfoundland-and-labrador-bariatric-surgery-cohort-study-rational-and-study-protocol
#18
Laurie K Twells, Deborah M Gregory, William K Midodzi, Carla Dillon, Christopher S Kovacs, Don MacDonald, Kendra K Lester, David Pace, Chris Smith, Darrell Boone, Raleen Murphy
BACKGROUND: In Canada, there has been a disproportionate increase in adults with Class II (BMI 35.0-39.9 kg/m(2)) or Class III obesity (BMI ≥ 40 kg/m(2)) affecting 9 % of Canadians with increases projected. Individuals affected by severe obesity (BMI ≥ 35) are at increased risk of high blood pressure, cardiovascular disease, diabetes, cancer, impaired quality of life, and premature mortality. Bariatric surgery is the most effective treatment for severe obesity. Laparoscopic sleeve gastrectomy (LSG), a relatively new type of bariatric surgery, is growing in popularity as a treatment...
October 28, 2016: BMC Health Services Research
https://www.readbyqxmd.com/read/27788744/-clinical-analysis-of-19-cases-of-pregnant-women-with-rapid-arrhythmia-in-the-treatment-of-radiofrequency-catheter-ablation
#19
L Chu, J Zhang, Y N Li, D Y Long
: Objective: To investigate the risk of radiofrequency catheter ablation and maternal and infant in pregnant women with rapid arrhythmia during pregnancy. Methods: The clinical data of the 19 cases of pregnancy complicated with rapid arrhythmia were retrospectively analyzed and followed up, including the gestational week, the type of arrhythmia, the treatment, and the outcome of the mother and child in Beijing Anzhen Hospital of Capital Medical University from January 2002 to March 2016...
October 25, 2016: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/27783022/new-trends-in-interventional-pulmonology
#20
Angela Roberts Selzer, Matthew Murrell, Eugene Shostak
PURPOSE OF REVIEW: As the field of interventional pulmonology continues to expand and develop at a rapid pace, anesthesiologists are increasingly called upon to provide well tolerated anesthetic care during these procedures. These patients may not be candidates for surgical treatment and often have multiple comorbidities. It is important for anesthesiologists to familiarize themselves with these procedures and their associated risks and complications. RECENT FINDINGS: The scope of the interventional pulmonologist's practice is varied and includes both diagnostic and therapeutic procedures...
October 25, 2016: Current Opinion in Anaesthesiology
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