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https://www.readbyqxmd.com/read/29665820/work-impairment-osteoarthritis-and-health-related-quality-of-life-among-employees-in-japan
#1
Ken Nakata, Toshinaga Tsuji, Jeffrey Vietri, Dena H Jaffe
BACKGROUND: Osteoarthritis (OA) is one of the most common causes of health and work impairment; however, this relationship, especially in Japan, is not well characterized. This study examined work impairment and OA in Japanese workers, specifically the relationship with health-related quality of life (HRQoL) and health status. METHODS: This retrospective, cross-sectional observational study included the data of employed adults with a self-reported OA diagnosis from the 2014 Japan National Health and Wellness Survey...
April 17, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29665258/health-related-quality-of-life-and-fall-risk-associated-with-age-related-body-composition-changes-sarcopenia-obesity-and-sarcopenic-obesity
#2
Zeynel Abidin Öztürk, İbrahim Halil Türkbeyler, Azer Abiyev, Seval Kul, Bahadır Edizer, Funda Datli Yakaryılmaz, Gülçimen Soylu
BACKGROUND: Sarcopenia, obesity, and sarcopenic obesity are various features of the aging process that can cause important health issues. The present study was undertaken to investigate the interrelationship between those body composition changes including their clinical components and the quality of life variables. METHODS: 423 individuals aged 65 years or more were included in this cross-sectional study. Sarcopenia was diagnosed according to The European Working Group on Sarcopenia in Older People criteria...
April 17, 2018: Internal Medicine Journal
https://www.readbyqxmd.com/read/29664456/quality-of-life-assessment-among-multiple-sclerosis-patients-in-saudi-arabia
#3
Adel A Alhazzani, Mohammed S Alqahtani, Mohammed S Alahmari, Muhannad A Asiri, Noof M Alamri, Leen A Sarhan, Shahad S Alkhashrami, Abdullmgeed A Asiri
OBJECTIVE: To determine the quality of life (QoL) among multiple sclerosis (MS) patients in Kingdom of Saudi Arabia. METHODS: A cross-sectional study was carried out to assess the QoL of MS patients during the period from November 2016 to May 2017. Patients were recruited from tertiary hospitals in 5 regions in the kingdom. Clinical and demographic data were collected and information on patients` health status using the self-report SF-36 questionnaire to assess QoL...
April 2018: Neurosciences: the Official Journal of the Pan Arab Union of Neurological Sciences
https://www.readbyqxmd.com/read/29664187/exercise-interventions-and-patient-beliefs-for-people-with-hip-knee-or-hip-and-knee-osteoarthritis-a-mixed-methods-review
#4
REVIEW
Michael Hurley, Kelly Dickson, Rachel Hallett, Robert Grant, Hanan Hauari, Nicola Walsh, Claire Stansfield, Sandy Oliver
BACKGROUND: Chronic peripheral joint pain due to osteoarthritis (OA) is extremely prevalent and a major cause of physical dysfunction and psychosocial distress. Exercise is recommended to reduce joint pain and improve physical function, but the effect of exercise on psychosocial function (health beliefs, depression, anxiety and quality of life) in this population is unknown. OBJECTIVES: To improve our understanding of the complex inter-relationship between pain, psychosocial effects, physical function and exercise...
April 17, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29663848/evaluation-of-the-association-between-sexual-dysfunction-and-demyelinating-plaque-location-and-number-in-female-multiple-sclerosis-patients
#5
Volkan Solmaz, Hatice Kose Ozlece, Aydın Him, Ayfer Güneş, Christian Cordano, Durdane Aksoy, Yahya Çelik
Purpose To investigate the frequency of sexual dysfunction (SD) in female multiple sclerosis (MS) patients and to explore its association with the location and number of demyelinating lesions. Material and Methods We evaluated 42 female patients and 41 healthy subjects. All patients underwent neurological examination and 1.5 T brain and full spinal MRI. All subjects completed the female sexual function index (FSFI), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and Short-Form 36 Quality of Life Scale (SF-36)...
April 17, 2018: Neurological Research
https://www.readbyqxmd.com/read/29663258/a-meta-analytic-review-of-measurement-equivalence-study-findings-of-the-sf-36%C3%A2-and-sf-12%C3%A2-health-surveys-across-electronic-modes-compared-to-paper-administration
#6
Michelle K White, Stephen M Maher, Avery A Rizio, Jakob B Bjorner
PURPOSE: Patient-reported outcome (PRO) measures originally developed for paper administration are increasingly being administered electronically in clinical trials and other health research studies. Three published meta-analyses of measurement equivalence among paper and electronic modes aggregated findings across hundreds of PROs, but there has not been a similar meta-analysis that addresses a single PRO, partly because there are not enough published measurement equivalence studies using the same PRO...
April 16, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/29663077/is-patient-reported-outcome-improved-by-nalfurafine-hydrochloride-in-patients-with-primary-biliary-cholangitis-and-refractory-pruritus-a-post-marketing-single-arm-prospective-study
#7
Minami Yagi, Atsushi Tanaka, Tadashi Namisaki, Atsushi Takahashi, Masanori Abe, Akira Honda, Yasushi Matsuzaki, Hiromasa Ohira, Hitoshi Yoshiji, Hajime Takikawa
BACKGROUND: Patients with primary biliary cholangitis (PBC) frequently suffer from pruritus, which can severely impair their health-related quality of life (HRQOL). Nalfurafine hydrochloride, a selective κ-opioid receptor agonist, was recently approved in Japan for refractory pruritus in patients with chronic liver diseases, but it still remains unclear whether this treatment improves the patient-reported outcome (PRO) in PBC patients with refractory pruritus. Herein, we conducted a multicenter, post-marketing, single-arm prospective study to investigate the efficacy of nalfurafine in terms of PRO, and the associations of the efficacy with any clinical characteristics...
April 16, 2018: Journal of Gastroenterology
https://www.readbyqxmd.com/read/29662746/the-predictive-value-of-preoperative-health-related-quality-of-life-scores-on-postoperative-patient-reported-outcome-scores-in-lumbar-spine-surgery
#8
Hwee Weng Dennis Hey, Nan Luo, Sze Yung Chin, Eugene Tze Chun Lau, Pei Wang, Naresh Kumar, Leok-Lim Lau, John Nathaniel Ruiz, Joseph Shanthakumar Thambiah, Ka-Po Gabriel Liu, Hee-Kit Wong
Study Design: A single-center, retrospective cohort study. Objective: To predict patient-reported outcomes (PROs) using preoperative health-related quality-of-life (HRQoL) scores by quantifying the correlation between them, so as to aid selection of surgical candidates and preoperative counselling. Methods: All patients who underwent single-level elective lumbar spine surgery over a 2-year period were divided into 3 diagnosis groups: spondylolisthesis, spinal stenosis, and disc herniation...
April 2018: Global Spine Journal
https://www.readbyqxmd.com/read/29662742/total-disc-replacement-versus-anterior-posterior-interbody-fusion-in-the-lumbar-spine-and-lumbosacral-junction-a-cost-analysis
#9
Timo Stubig, Malik Ahmed, Amir Ghasemi, Luigi Aurelio Nasto, Michael Grevitt
Study Design: Prospective observational cohort study. Objectives: To analyze clinical and economic results in patients with degenerative disc disease in the lumbar area for patients who received combined anterior and posterior fusion or total disc replacement (TDR). Methods: The study included 75 patients, 38 in the fusion group and 37 in the TDR group, who received either anterior/posterior fusion or TDR for lumbar disc disease from January 2005 to December 2008 with a minimum follow-up of 24 months...
April 2018: Global Spine Journal
https://www.readbyqxmd.com/read/29662741/predictive-factors-for-the-outcome-of-surgical-treatment-of-lumbar-spondylolysis-in-young-sporting-individuals
#10
Ujjwal K Debnath, B E Scammell, Brian J C Freeman, Jeffrey R McConnell
Study Design: Retrospective consecutive case series. Objectives: Only few sporting individuals with symptomatic lumbar pars injuries require surgical repair and it is often difficult to predict the outcome following surgery. The factors that predict the outcome after direct repair of lumbar pars defect was evaluated clinically and statistically. The preoperative background variables both subjective and objective as well as radiological evaluation were used in a multiple regression model to find the strong predictors of postoperative outcome as measured by VAS (visual analogue scores), ODI (Oswestry Disability Index) and SF-36 (Short Form)...
April 2018: Global Spine Journal
https://www.readbyqxmd.com/read/29661674/evaluation-of-transsyndesmotic-fixation-and-primary-deltoid-ligament-repair-in-ankle-fractures-with-suspected-combined-deltoid-ligament-injury
#11
Kai Wu, Jian Lin, Jianhua Huang, Qiugen Wang
The present prospective study examined the utility of the intraoperative tap test/technique for distal tibiofibular syndesmosis in the diagnosis of deltoid ligament rupture and compared the outcomes of transsyndesmotic fixation to deltoid ligament repair with suture anchor. This diagnostic technique was performed in 59 ankle fractures with suspected deltoid ligament injury. The width of the medial clear space of 59 cases was evaluated to assess the sensitivity and specificity. Those with deltoid ligament rupture were randomly assigned to 2 groups and treated with deltoid ligament repair with a suture anchor or with syndesmosis screw fixation...
April 13, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29659717/statin-treatment-is-associated-with-a-neutral-effect-on-health-related-quality-of-life-among-community-dwelling-octogenarian-men
#12
Timo E Strandberg, Annele Urtamo, Juuso Kähärä, Arto Y Strandberg, Kaisu H Pitkälä, Hannu Kautiainen
Background: Statin treatment is common among 80+ people, but little is known about statin effects on health-related quality of life (HRQoL) in this oldest age group. Methods: In the Helsinki Businessmen Study (HBS), men born 1919 to 1934 (original n=3490), have been followed-up since the 1960s. In 2015, a questionnaire about lifestyle, diseases and medications, and including RAND-36/SF-36 HRQoL instrument was mailed to survivors. 612 men (72.6%) responded, 530 of them reporting their medications (98% community-living)...
April 12, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29659589/correlation-between-physical-markers-and-psychiatric-health-in-a-portuguese-systemic-lupus-erythematosus-cohort-the-role-of-suffering-in-chronic-autoimmune-disease
#13
Margarida Figueiredo-Braga, Caleb Cornaby, Miguel Bernardes, Marta Figueiredo, Cristina Dos Santos Mesquita, Lúcia Costa, Brian D Poole
BACKGROUND: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects a large number of people throughout the world. Anxiety, depression and fatigue are common symptoms of SLE that substantially contribute to decreased quality of life. This study investigates the interplay between physical and psychiatric manifestations of lupus. To this end, an SLE patient cohort was examined for correlations between clinical presentation, laboratory tests, and psychological indicators...
2018: PloS One
https://www.readbyqxmd.com/read/29659544/health-related-quality-of-life-in-patients-with-arthritis-a-cross-sectional-survey-among-middle-aged-adults-in-chongqing-china
#14
Yunshuang Rao, Xianglong Xu, Dengyuan Liu, Cesar Reis, Ian M Newman, Liqiang Qin, Manoj Sharma, Jun Shen, Yong Zhao
Background: Arthritis is a common disease in China, but few studies have been conducted to explore the associated health-related quality of life (HRQoL) and its influencing factors in Chongqing, China. This study aimed to explore the association of arthritis and HRQoL and probe factors affecting HRQoL among arthritis patients. METHODS: A cross-sectional survey was conducted in Chongqing, China. A total of 1224 adults were included in the analysis. Medical Outcomes Study Short Form 36 Health Survey (SF-36) was used to measure HRQoL...
April 16, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29658834/alterations-in-thyroid-hormone-levels-following-growth-hormone-replacement-exert-complex-biological-effects
#15
Nigel Glynn, Helena Kenny, Tarik Salim, David J Halsall, Diarmuid Smith, Tommy Kyaw Tun, John H McDermott, William Tormey, Christopher J Thompson, Brendan McAdam, Donal O' Gorman, Amar Agha
OBJECTIVE: Alterations in the thyroid axis are frequently observed following growth hormone (GH) replacement, but uncertainty exists regarding their clinical significance. We aimed to compare fluctuations in circulating thyroid hormone levels, induced by GH, to changes in sensitive biological markers of thyroid hormone action. METHODS: This was a prospective observational clinical study. Twenty hypopituitary men were studied before and after GH replacement. Serum thyroid-stimulating hormone (TSH), thyroid hormones, and insulin-like growth factor 1 were measured...
April 2018: Endocrine Practice
https://www.readbyqxmd.com/read/29658804/comparison-of-effects-of-endurance-and-strength-training-programs-in-patients-with-copd
#16
Michael J Berry, Katherine L Sheilds, Norman E Adair
Comparisons between endurance and strength training in chronic obstructive pulmonary disease (COPD) patients have produced equivocal findings when examining physical function and health-related quality of life (HRQL). One reason for these differences may be due to individual patient responses to the different training modalities. PURPOSE: To compare changes in physical function and HRQL in a group of COPD patients completing both an endurance and a strength training program. METHODS: Eleven mildly diseased patients completed a three month endurance training program and, approximately 5 years later, completed a three month strength training program...
April 16, 2018: COPD
https://www.readbyqxmd.com/read/29658344/effect-of-12-month-treatment-with-metformin-and-or-oral-contraceptives-on-health-related-quality-of-life-in-polycystic-ovary-syndrome
#17
Magda Lambaa Altinok, Pernille Ravn, Marianne Andersen, Dorte Glintborg
Health-related quality of life (HRQoL) is impaired in polycystic ovary syndrome (PCOS), but the effect of treatment with metformin (M) and/or oral contraceptives (OCP) is undetermined. To assess changes in HRQoL during 12-month randomized treatment with M, OCP or M + OCP in PCOS. Ninety women with PCOS were randomized to treatment with M, OCP or M + OCP. HRQoL was evaluated by a PCOS-specific visual analog scale (PCOS-VAS) regarding 1: Facial hair, 2: Body hair, 3: Acne, 4: Irregular menses, 5: Weight and 6: PCOS in general, and Short Form 36 (SF-36)...
April 16, 2018: Gynecological Endocrinology
https://www.readbyqxmd.com/read/29658202/physical-training-in-a-medical-fitness-room-for-patients-with-chronic-diseases-functional-and-metabolic-outcomes
#18
Oshrat E Tayer-Shifman, Yigal Bar-On, David Pereg, Alon Y Hershko
BACKGROUND: Physical inactivity is a pivotal factor in the development and progression of various chronic diseases. However, most fitness facilities exclude unhealthy individuals. Therefore, an exercise program that admits such patients is imperative. OBJECTIVES: To evaluate the effectiveness of a fitness facility that admits adult subjects with multiple chronic diseases. METHODS: We conducted a retrospective screening of patient records from the Medical Fitness Facility at Meir Medical Center, Israel...
January 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29657870/is-the-serum-oxytocin-level-altered-by-treatment-in-rheumatoid-arthritis-patients-complicated-with-depression
#19
Yusuke Miwa, Hidekazu Furuya, Ryo Yanai, Tsuyoshi Kasama, Kenji Sanada
Objective: The objective of this study was to investigate the factors associated with depression, including serum oxytocin (OXT) levels, disease activity, activities of daily living (ADL), and quality of life (QOL), and their effects on rheumatoid arthritis (RA). Methods: This study included 42 RA patients who received treatment with a biological agent. We measured the following variables before and after 6 months of treatment: baseline characteristics, including age, sex, disease duration, smoking, and body mass index (BMI); prednisolone and methotrexate dose; serum level of matrix metalloproteinase-3 (MMP-3); erythrocyte sedimentation rate (ESR); and C-reactive protein (CRP) level...
March 2018: European Journal of Rheumatology
https://www.readbyqxmd.com/read/29653440/long-term-outcome-after-dynamic-graciloplasty-for-treatment-of-persistent-fecal-incontinence-in-patients-with-anorectal-malformations
#20
Johan Danielson, Urban Karlbom, Tomas Wester, Wilhelm Graf
PURPOSE:  Dynamic graciloplasty (DGP) has been used to treat severe fecal incontinence since the 1980s. Previous studies have shown an inferior outcome in patients with anorectal malformations (ARMs). Our experience has been that DGP has been appreciated by ARM -patients. The objective of the study was to evaluate the long-term outcome of DGP in our patients with ARM compared with patients with other underlying conditions. MATERIALS AND METHODS:  Twenty-three patients operated with DGP at our institution from 1996 to 2010 were sent validated bowel function and quality of life questionnaires...
April 13, 2018: European Journal of Pediatric Surgery
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