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https://www.readbyqxmd.com/read/29044337/beneficial-effects-of-intradialytic-cardiopulmonary-rehabilitation
#1
Bruno Medeiros Guio, Carlos Perez Gomes, Fabio Brandão da Costa, Adriana Dos Santos de Oliveira, Marta Turano Duarte, Maurilo Leite
INTRODUCTION: Patients on hemodialysis (HD) present high mortality from cardiovascular complications and high morbidity, including decreasing functional capacity and quality of life. OBJECTIVE: To analyze clinical and laboratory responses of patients in HD to intradialytic cardiopulmonary rehabilitation on an outpatient basis. METHODS: We evaluated 14 patients in a prospective study for 8 months using cardiopulmonary rehabilitation protocol (CRehab) consisted of intradialytic aerobic exercise with a cycle ergometer...
July 2017: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/29044302/functional-ability-in-younger-and-older-elderlies-after-discharge-from-the-intensive-care-unit-a-prospective-cohort
#2
Camila Dietrich, Juliana Rezende Cardoso, Fernanda Vargas, Evelin Carneiro Sanchez, Francine Hoffmann Dutra, Cátia Moreira, Marina Bessel, Caroline Robinson, Maicon Falavigna, Cassiano Teixeira
OBJECTIVE: To compare the functional capacity of younger elderly individuals (60 to 79 years old) with that of older elderly individuals (≥ 80 years old) during the first 6 months after discharge from the intensive care unit. METHODS: A multicenter prospective cohort study was conducted, in which data on intensive care unit admission and outcomes after hospital discharge (immediate post-discharge, after 3 months and after 6 months) were collected. Muscle strength was evaluated through the protocol of the Medical Research Council and dynamometry (handgrip); the ability to perform activities of daily life and functional independence were assessed by the Barthel index and the usual level of physical activity (International Physical Activity Questionnaire); and quality of life was assessed by the 12-Item Short-Form Health Survey Version 2...
July 2017: Revista Brasileira de Terapia Intensiva
https://www.readbyqxmd.com/read/29040321/co-delivery-of-micronized-urinary-bladder-matrix-damps-regenerative-capacity-of-minced-muscle-grafts-in-the-treatment-of-volumetric-muscle-loss-injuries
#3
Stephen M Goldman, Benjamin T Corona
Minced muscle grafts (MG) promote de novo muscle fiber regeneration and neuromuscular strength recovery in small and large animal models of volumetric muscle loss. The most noteworthy limitation of this approach is its reliance on a finite supply of donor tissue. To address this shortcoming, this study sought to evaluate micronized acellular urinary bladder matrix (UBM) as a scaffolding to promote in vivo expansion of this MG therapy in a rat model. Rats received volumetric muscle loss injuries to the tibialis anterior muscle of their left hind limb which were either left untreated or repaired with minced muscle graft at dosages of 50% and 100% of the defect mass, urinary bladder matrix in isolation, or a with an expansion product consisting of a combination of the two putative therapies in which the minced graft is delivered at a dosage of 50% of the defect mass...
2017: PloS One
https://www.readbyqxmd.com/read/29037615/six-weeks-of-mat-pilates-training-are-enough-to-improve-functional-capacity-in-elderly-women
#4
Josefina Bertoli, Grazieli Maria Biduski, Cíntia de la Rocha Freitas
The aim of the study was to evaluate the effect of Mat Pilates on the functional capacity (FC) of elderly women before and after six weeks of intervention. Eighteen women aged 62.28 (±2.34) participated in the study. Timed Up and Go test, Timed Up Stairs, Timed Down Stairs, 30-s Chair Stand, Chair Sit-and-Reach and Back Scratch tests were assessed. The results showed significant improvements in all FC tests after six weeks of the Mat Pilates intervention. Summarizing, only six weeks of Mat Pilates training of 60 min per session, three times a week, three series beginning with six repetitions and eight repetitions at the last two weeks of intervention, were enough to improve FC in elderly women...
October 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29036861/task-intensity-influences-upper-limb-and-torso-kinematics-during-two-common-overhead-functional-capacity-evaluation-tasks
#5
Angelica E Lang, Clark R Dickerson
BACKGROUND: The Functional Capacity Evaluation (FCE) is a tool used in the return-to-work process to guide treatment and decision making. Individual abilities and maximum capacity can be determined through visual observations of changes in mechanics as intensity increases. OBJECTIVE: The purpose of this study was to determine kinematic differences between sexes and intensity levels of two common FCE tasks to establish normative behaviours. METHODS: Upper limb and torso kinematics were collected from 30 participants as they performed the overhead lift and overhead work FCE tasks...
October 8, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/29034728/the-language-of-percentages-ranking-bodies-shaping-realities-and-limiting-opportunities
#6
Rannveig Svendby, Grace Inga Romsland, Kåre Moen
PURPOSE: This exploratory study is situated in a critical tradition. It aims to describe and analyse the reliance on percentage assessments of functional capacity among a group of young adults in rehabilitation after serious motor vehicle accidents. METHODS: Qualitative interviews and participant observation. Thematic and theoretically informed analysis was carried out. RESULTS: The concept of percentages played a significant role in the study participants' meaning-making processes as they went through rehabilitation...
October 15, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29033856/possible-facilitative-effects-of-repeated-anodal-transcranial-direct-current-stimulation-on-functional-outcome-1-month-later-in-schizophrenia-an-open-trial
#7
Zui Narita, Takuma Inagawa, Kazuki Sueyoshi, Crystal Lin, Tomiki Sumiyoshi
Recent research on neuromodulation techniques, such as transcranial direct current stimulation (tDCS), for the treatment of schizophrenia has mainly focused on psychotic symptoms. We aimed to determine whether repetitive tDCS is efficacious in improving determinants of outcome, such as cognitive function, daily living skills, and depressive mood in patients with schizophrenia. Twenty-eight patients underwent tDCS (2 mA × 20 min) two times per day for 5 consecutive days. The anodal electrode was placed over the left dorsolateral prefrontal cortex while the cathodal electrode was placed over the right supraorbital region...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29033514/the-association-between-cha2ds2-vasc-score-and-mortality-in-patients-with-heart-failure-with-reduced-ejection-fraction
#8
Orkun Temizer, Burak Açar, Çağrı Yayla, Sefa Ünal, Ahmet Göktuğ Ertem, Esra Gücük İpek, Uğur Canpolat, Bihter Şentürk, Hatice Selçuk, Timur Selçuk
BACKGROUND: Heart failure (HF) is associated with significant mortality and morbidity. Therefore, identifying high-risk patients may optimize treatment for HF patients and reduce adverse events. The aim of this study was to assess the role of the CHA2DS2-VASc score to predict mortality in patients with reduced left ventricular ejection fraction (LVEF). METHODS: A total of 106 patients with reduced LVEF were enrolled in this study. All patients completed a one-year follow-up, and a CHA2DS2-VASc score was calculated for each patient...
July 2017: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/29028873/mirna-in-tumour-metabolism-and-why-could-it-be-the-preferred-pathway-for-energy-reprograming
#9
Aliaa A Alamoudi, Amina Alnoury, Hoda Gad
The current literature on the role of microRNA (miRNA) in tumour metabolism is growing, and a number of studies regularly confirm the impact miRNA can have in energy reprograming in tumours. However, there remains to be a lack of understanding of the larger perspective of the role of miRNA in the metabolism story. In the first part of this review, we provide a comprehensive and up-to-date description of the extensive role of miRNAs in tumour metabolism including glucose, lipid and amino acid metabolism. However, in the second part, we aim to provide a description of the multidimensional role miRNA can be playing in tumour metabolism...
September 23, 2017: Briefings in Functional Genomics
https://www.readbyqxmd.com/read/29027656/pulmonary-complications-after-non-cardiac-surgeries-temporal-patterns-and-risk-factors
#10
Cássia Toledo, Flávio Eduardo Nácul, Marcos Freitas Knibel, Nilton Brandão Silva, Ederlon Rezende, Cintia Magalhães Carvalho Grion, Murillo Assunção, Fernando Gutierrez, Joelma Villafanha Gandolfi, Suzana Margareth Lobo
BACKGROUND: Postoperative complications are the primary determinants of survival following major surgery. We aimed to characterize the early perioperative risk factors for postoperative pulmonary complications (POPCs) in patients undergoing major non-cardiac surgeries. METHODS: This study utilized a multicenter prospective observational cohort design. Adult patients undergoing non-cardiac surgeries and admitted to 21 Brazilian ICUs were screened for inclusion in the study...
October 13, 2017: Anaesthesiology Intensive Therapy
https://www.readbyqxmd.com/read/29023636/revised-functional-capacity-index-as-a-predictor-of-outcome-following-injury
#11
C S Palmer, B J Gabbe, P A Cameron
BACKGROUND: Assessment of functional outcomes in survivors of severe injury is an identified priority for trauma systems. The predictive Functional Capacity Index (pFCI) within the 2008 Abbreviated Injury Scale dictionary (pFCI08) offers a widely available tool for predicting functional outcomes without requiring long-term follow-up. This study aimed to assess the 12-month functional outcome predictions of pFCI08 in a major trauma population, and to test the assumptions made by its developers to ensure population homogeneity...
October 12, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/29021910/the-training-type-influence-on-male-elite-athletes-ventilatory-function
#12
Tijana Durmic, Biljana Lazovic Popovic, Mirjana Zlatkovic Svenda, Marina Djelic, Vladimir Zugic, Tamara Gavrilovic, Zoran Mihailovic, Marija Zdravkovic, Roman Leischik
BACKGROUND/AIM: To assess and compare measured ventilatory volumes (forced expiratory volume in 1 s (FEV1), peak expirium flow (PEF) and maximal voluntary ventilation (MVV)), ventilatory function capacities (forced vital capacity (FVC) and vital capacity (VC)) and FEV1/VC ratio in a sample of power and endurance elite athletes and their age-matched and sex-matched sedentary control group. METHODS: A cross-sectional study was applied on male elite athletes (n=470) who were classified according to the type of the predominantly performed exercise in the following way: group 1: endurance group (EG=270), group 2: power athletes group (SG=200) and group 3: sedentary control group (CG=100)...
2017: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/29020525/social-determinants-of-adherence-to-pulmonary-rehabilitation-for-chronic-obstructive-pulmonary-disease
#13
Gabriela R Oates, Bryant W Hamby, Irena Stepanikova, Sara J Knight, Surya P Bhatt, Jason Hitchcock, Christopher Schumann, Mark T Dransfield
Adherence to pulmonary rehabilitation (PR) is low. Previous studies have focused on clinical predictors of PR completion. We aimed to identify social determinants of adherence to PR. A cross-sectional analysis of a database of COPD patients (N = 455) in an outpatient PR program was performed. Adherence, a ratio of attended-to-prescribed sessions, was coded as low (<35%), moderate (35-85%), and high (>85%). Individual-level measures included age, sex, race, BMI, smoking status, pack-years, baseline 6-minute walk distance (6MWD: <150, 150-249, ≥250), co-morbidities, depression, and prescribed PR sessions (≤20, 21-30, >30)...
October 11, 2017: COPD
https://www.readbyqxmd.com/read/29020257/reappraising-myocardial-fibrosis-in-severe-aortic-stenosis-an-invasive-and-non-invasive-study-in-133-patients
#14
Thomas A Treibel, Begoña López, Arantxa González, Katia Menacho, Rebecca S Schofield, Susana Ravassa, Marianna Fontana, Steven K White, Carmelo DiSalvo, Neil Roberts, Michael T Ashworth, Javier Díez, James C Moon
Aims: To investigate myocardial fibrosis (MF) in a large series of severe aortic stenosis (AS) patients using invasive biopsy and non-invasive imaging. Methods and results: One hundred thirty-three patients with severe, symptomatic AS accepted for surgical aortic valve replacement underwent cardiovascular magnetic resonance (CMR) with late gadolinium enhancement (LGE) and extracellular volume fraction (ECV) quantification. Intra-operative left ventricular (LV) biopsies were performed by needle or scalpel, yielding tissue with (n = 53) and without endocardium (n = 80), and compared with 10 controls...
July 22, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29018363/moderate-load-muscular-endurance-strength-training-did-not-improve-peak-power-or-functional-capacity-in-older-men-and-women
#15
Simon Walker, Guy G Haff, Keijo Häkkinen, Robert U Newton
The present study determined the effects of muscular endurance strength training on maximum strength and power, functional capacity, muscle activation and hypertrophy in older men and women. Eighty-one men and women acted as an intervention group while 22 acted as non-training controls (age range 64-75 y). Intervention training included super-sets (i.e., paired exercises, immediately performing the second exercises following completion of the first) with short rest intervals (30-60 s between sets) at an intensity of 50-60% one-repetition maximum (1-RM) for 15-20 repetitions...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29018189/the-gut-microbiome-in-atherosclerotic-cardiovascular-disease
#16
Zhuye Jie, Huihua Xia, Shi-Long Zhong, Qiang Feng, Shenghui Li, Suisha Liang, Huanzi Zhong, Zhipeng Liu, Yuan Gao, Hui Zhao, Dongya Zhang, Zheng Su, Zhiwei Fang, Zhou Lan, Junhua Li, Liang Xiao, Jun Li, Ruijun Li, Xiaoping Li, Fei Li, Huahui Ren, Yan Huang, Yangqing Peng, Guanglei Li, Bo Wen, Bo Dong, Ji-Yan Chen, Qing-Shan Geng, Zhi-Wei Zhang, Huanming Yang, Jian Wang, Jun Wang, Xuan Zhang, Lise Madsen, Susanne Brix, Guang Ning, Xun Xu, Xin Liu, Yong Hou, Huijue Jia, Kunlun He, Karsten Kristiansen
The gut microbiota has been linked to cardiovascular diseases. However, the composition and functional capacity of the gut microbiome in relation to cardiovascular diseases have not been systematically examined. Here, we perform a metagenome-wide association study on stools from 218 individuals with atherosclerotic cardiovascular disease (ACVD) and 187 healthy controls. The ACVD gut microbiome deviates from the healthy status by increased abundance of Enterobacteriaceae and Streptococcus spp. and, functionally, in the potential for metabolism or transport of several molecules important for cardiovascular health...
October 10, 2017: Nature Communications
https://www.readbyqxmd.com/read/29016675/effect-of-small-sided-team-sport-training-and-protein-intake-on-muscle-mass-physical-function-and-markers-of-health-in-older-untrained-adults-a-randomized-trial
#17
Jacob Vorup, Mogens Theisen Pedersen, Lena Kirchner Brahe, Pia Sandfeld Melcher, Joachim Meno Alstrøm, Jens Bangsbo
The effect of small-sided team sport training and protein intake on muscle mass, physical function, and adaptations important for health in untrained older adults was examined. Forty-eight untrained older (72±6 (±standard deviation, SD) years men and women were divided into either a team sport group ingesting a drink high in protein (18 g) immediately and 3 h after each training session (TS-HP, n = 13), a team sport group ingesting an isocaloric drink with low protein content (3 g; TS-LP, n = 18), or a control group continuing their normal activities (CON, n = 17)...
2017: PloS One
https://www.readbyqxmd.com/read/28994704/characterization-of-mucosal-disaccharidases-from-human-intestine
#18
Mahdi Amiri, Hassan Y Naim
In this study, we used a brush border membrane (BBM) preparation from human small intestine to analyze the proportion and the activity of major intestinal disaccharidases, including sucrase-isomaltase (SI), maltase-glucoamylase (MGAM) and lactase-phlorizin hydrolase (LPH). SI, MGAM and LPH respectively constituted 8.2%, 2.7% and 1.4% of total BBM protein. The activity of SI and LPH decreased threefold after purification from the brush border membrane, which highlights the effect of membrane microdomains on the functional capacity of these enzymes...
October 10, 2017: Nutrients
https://www.readbyqxmd.com/read/28993389/innovative-telemonitoring-enhanced-care-programme-for-chronic-heart-failure-itec-chf-to-improve-guideline-compliance-and-collaborative-care-protocol-of-a-multicentre-randomised-controlled-trial
#19
Hang Ding, Rajiv Jayasena, Andrew Maiorana, Alison Dowling, Sheau Huey Chen, Mohan Karunanithi, Jamie Layland, Iain Edwards
INTRODUCTION: Chronic heart failure (CHF) is a life-threatening chronic disease characterised by periodic exacerbations and recurrent hospitalisations. In the management of CHF, patient compliance with evidence-based clinical guidelines is essential, but remains difficult practically. The objective of this study is to examine whether an Innovative Telemonitoring Enhanced Care Programme for CHF (ITEC-CHF) improves patients' compliance, and associated health and economic outcomes. METHODS AND ANALYSIS: An open multicentre randomised controlled trial has been designed...
October 8, 2017: BMJ Open
https://www.readbyqxmd.com/read/28990960/anesthesia-simulator-based-functional-capacity-evaluation-of-an-anesthesiologist-after-radial-fracture-a-case-report
#20
Ceferina Suarez, Jesús Maxide, Demian Szyld, Jose M Maestre
We used simulation as a job-specific functional capacity evaluation method after a distal radius fracture in an anesthesiologist. Treatment included open reduction followed by an internal fixation with an arthrodesis plate. The patient performed simulated anesthesia inductions to assess her response to endotracheal intubation, bag-mask ventilation, and the manual opening of the airway. Data collected helped to guide the rehabilitation protocol, and to assess pain and the time to safely return to work. The patient began her clinical duties after 7 weeks of therapy and was able to fully perform her daily tasks with confidence, and full functional capacity...
October 5, 2017: A & A Case Reports
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