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https://www.readbyqxmd.com/read/29223009/influence-of-spermatozoal-lipidomic-profile-on-the-cryoresistance-of-frozen-spermatozoa-from-stallions
#1
T Cabrera, C Ramires-Neto, K R A Belaz, C P Freitas-Dell'aqua, D Zampieri, A Tata, M N Eberlin, M A Alvarenga, F F Souza
The membrane of spermatozoa, which contributes to cellular cryoresistance, contains numerous lipids with a composition that directly affects membrane fluidity and the fertilization process. In light of variations in the degree of sensitivity in equine seminal freezing, this study aimed to correlate equine semen lipids with post-thawing characteristics of spermatozoa. We used ejaculates from 34 stallions, which were evaluated (total motility ≥ 60%), frozen and thawed and reevaluated for motility of spermatozoa, membrane integrity and lipid peroxidation...
November 26, 2017: Theriogenology
https://www.readbyqxmd.com/read/29222609/evaluating-cognition-in-individuals-with-huntington-disease-neuro-qol-cognitive-functioning-measures
#2
Jin-Shei Lai, Siera Goodnight, Nancy R Downing, Rebecca E Ready, Jane S Paulsen, Anna L Kratz, Julie C Stout, Michael K McCormack, David Cella, Christopher Ross, Jenna Russell, Noelle E Carlozzi
PURPOSE: Cognitive functioning impacts health-related quality of life (HRQOL) for individuals with Huntington disease (HD). The Neuro-QoL includes two patient-reported outcome (PRO) measures of cognition-Executive Function (EF) and General Concerns (GC). These measures have not previously been validated for use in HD. The purpose of this analysis is to evaluate the reliability and validity of the Neuro-QoL Cognitive Function measures for use in HD. METHODS: Five hundred ten individuals with prodromal or manifest HD completed the Neuro-QoL Cognition measures, two other PRO measures of HRQOL (WHODAS 2...
December 8, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/29217278/colistin-exposure-as-a-risk-factor-for-infections-caused-by-inherently-colistin-resistant-enterobacteriaceae-a-case-control-study
#3
G Drozdinsky, H Ben-Zvi, S Kushnir, L Leibovici, D Yahav
OBJECTIVES: Epidemiological studies have suggested an association between increased colistin use and selection for inherently colistin resistant Enterobacteriaceae (ICRE). We aimed to evaluate whether colistin exposure is a risk factor for ICRE infection. METHODS: A matched 1:1 case-control study including patients recently hospitalized for >=14 days with ICRE infection as cases matched with similar patients with a clinical isolate of a colistin susceptible Enterobacteriaceae as controls was performed...
December 4, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29214924/different-protein-and-derivatives-supplementation-strategies-combined-with-resistance-training-in-pre-frail-and-frail-elderly-rationale-and-protocol-for-the-pro-elderly-study
#4
Alan Lins Fernandes, Ana Paula Hayashi, José Claudio Jambassi-Filho, Mariana Dutilh de Capitani, Davi Alves de Santana, Bruno Gualano, Hamilton Roschel
BACKGROUND: Frailty is a multifactorial geriatric syndrome characterized by progressive decline in health and associated with decreased muscle mass, strength, and functional capacity. Resistance training (RT) combined with protein or amino acids supplementation has been shown to be promising for mitigating age-related impairments. AIM: To investigate the chronic effects of different strategies of protein and derivatives supplementation in association with RT on selected health-related parameters in pre-frail and frail elderly...
December 2017: Nutrition and Health
https://www.readbyqxmd.com/read/29214519/functional-capacity-improves-in-line-with-neuromuscular-performance-after-12%C3%A2-weeks-of-non-linear-periodization-strength-training-in-the-elderly
#5
Bruno Monteiro de Moura, Raphael Luiz Sakugawa, Lucas Bet da Rosa Orssatto, Luis Antonio Pereira de Lima, Ronei Silveira Pinto, Simon Walker, Fernando Diefenthaeler
BACKGROUND: While it is accepted that resistance training can improve functional capacity in older individuals, the neuromuscular source of this improvement has yet to be identified. AIM: This study investigated the link between improved neuromuscular performance and functional capacity after a 12-week resistance training period in untrained healthy older individuals. METHODS: Fifteen older men and women (60-71 years) adhered to a 4-week control period, followed by 12 weeks of non-linear resistance training for the lower limbs...
December 6, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29213491/prevalence-of-functional-cognitive-impairment-and-associated-factors-in-brazilian-community-dwelling-older-adults
#6
Andréa Silva Gondim, João Macedo Coelho Filho, Alexandre de Andrade Cavalcanti, Jarbas de Sá Roriz Filho, Charlys Barbosa Nogueira, Arnaldo Aires Peixoto Junior, José Wellington de Oliveira Lima
The identification of the prevalence of cognitive impairment and associated factors among older adults is important in countries facing rapid demographic transition, given the significant implications for public policy and health planning. Objective: To determine the prevalence of functional cognitive impairment (FCI) and associated factors in Brazilian community-dwelling older adults. Methods: A cross-sectional study involving 461 elderly subjects residing in Fortaleza city, Ceará was conducted...
January 2017: Dementia & Neuropsychologia
https://www.readbyqxmd.com/read/29211225/off-pump-versus-on-pump-coronary-artery-bypass-grafting-in-frail-patients-study-protocol-for-the-fragile-multicenter-randomized-controlled-trial
#7
Omar Asdrúbal Vilca Mejía, Michel Pompeu Barros Oliveira Sá, Maurilio Onofre Deininger, Luís Roberto Palma Dallan, Rodrigo Coelho Segalote, Marco Antonio Praça de Oliveira, Fernando Antibas Atik, Magaly Arrais Dos Santos, Pedro Gabriel Melo de Barros E Silva, Rodrigo Mussi Milani, Alexandre Ciappina Hueb, Rosangela Monteiro, Ricardo Carvalho Lima, Luiz Augusto Ferreira Lisboa, Luís Alberto Oliveira Dallan, John Puskas, Fabio Biscegli Jatene
INTRODUCTION: Advances in modern medicine have led to people living longer and healthier lives. Frailty is an emerging concept in medicine yet to be explored as a risk factor in cardiac surgery. When it comes to CABG surgery, randomized controlled clinical trials have primarily focused on low-risk (ROOBY, CORONARY), elevated-risk (GOPCABE) or high-risk patients (BBS), but not on frail patients. Therefore, we believe that off-pump CABG could be an important technique in patients with limited functional capacity to respond to surgical stress...
September 2017: Brazilian Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29210997/tempol-supplementation-restores-diaphragm-force-and-metabolic-enzyme-activities-in-mdx-mice
#8
David P Burns, Izza Ali, Clement Rieux, James Healy, Greg Jasionek, Ken D O'Halloran
Duchenne muscular dystrophy (DMD) is characterized by striated muscle weakness, cardiomyopathy, and respiratory failure. Since oxidative stress is recognized as a secondary pathology in DMD, the efficacy of antioxidant intervention, using the superoxide scavenger tempol, was examined on functional and biochemical status of dystrophin-deficient diaphragm muscle. Diaphragm muscle function was assessed, ex vivo, in adult male wild-type and dystrophin-deficient mdx mice, with and without a 14-day antioxidant intervention...
December 6, 2017: Antioxidants (Basel, Switzerland)
https://www.readbyqxmd.com/read/29210931/phase-angle-is-moderately-associated-with-muscle-quality-and-functional-capacity-independent-of-age-and-body-composition-in-older-women
#9
Crisieli M Tomeleri, Edilaine F Cavalcante, Melissa Antunes, Hellen C G Nabuco, Mariana F de Souza, Denilson C Teixeira, Luis A Gobbo, Analiza M Silva, Edilson S Cyrino
BACKGROUND AND PURPOSE: There is a growing body of evidence indicating that phase angle (PhA) can be used as an indicator of nutritional status, disease prognosis, and mortality risk; however, it is still unknown whether PhA can be used as an explanator of functional capacity and muscle quality in older women. The main purpose of this cross-sectional study was to explore whether PhA is associated with muscle quality and functional capacity in older women, regardless of total and regional body composition...
November 28, 2017: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/29206761/skeletal-muscle-mitochondrial-function-is-determined-by-burn-severity-sex-and-sepsis-and-is-associated-with-glucose-metabolism-and-functional-capacity-in-burned-children
#10
Victoria G Rontoyanni, Ioannis Malagaris, David N Herndon, Eric Rivas, Karel D Capek, Anahi D Delgadillo, Nisha Bhattarai, Armando Elizondo, Charles D Voigt, Celeste C Finnerty, Oscar E Suman, Craig Porter
BACKGROUND: Restoring normal mitochondrial function represents a new target for strategies aimed at mitigating the stress response to severe burn trauma and hastening recovery. Our objective was to investigate the determinants of skeletal muscle mitochondrial respiratory capacity and function and its association with glucose metabolism and functional capacity in burned children. METHODS: Data from burned children enrolled in the placebo arm of an ongoing prospective clinical trial were analyzed...
December 4, 2017: Shock
https://www.readbyqxmd.com/read/29203160/myocardial-strain-may-predict-exercise-tolerance-in-patients-with-reduced-and-mid-range-ejection-fraction
#11
Elias Tsougos, George Angelidis, Elias Gialafos, Chara Tzavara, Vaios Tzifos, Ioannis Tsougos, Panagiotis Georgoulias
BACKGROUND: Conventional echocardiographic parameters, such as rest ejection fraction, perform poorly regarding the prediction of exercise tolerance in heart failure. The aim of the present study was to evaluate the contribution of hemodynamic instability in the observed lower functional capacity, investigating the role of left ventricular strain for the prediction of stress test duration in obese hypertensive patients with reduced ejection fraction. METHODS: Sixty-one patients with reduced ejection fraction underwent treadmill exercise echocardiography...
December 1, 2017: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/29202845/robotic-assisted-gait-as-a-tool-for-rehabilitation-of-individuals-with-spinal-cord-injury-a-systematic-review
#12
REVIEW
Ledycnarf J Holanda, Patrícia M M Silva, Thiago C Amorim, Matheus O Lacerda, Camila R Simão, Edgard Morya
BACKGROUND: Spinal cord injury (SCI) is characterized by a total or partial deficit of sensory and motor pathways. Impairments of this injury compromise muscle recruitment and motor planning, thus reducing functional capacity. SCI patients commonly present psychological, intestinal, urinary, osteomioarticular, tegumentary, cardiorespiratory and neural alterations that aggravate in chronic phase. One of the neurorehabilitation goals is the restoration of these abilities by favoring improvement in the quality of life and functional independence...
December 4, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/29202745/the-association-of-n-terminal-pro-brain-type-natriuretic-peptide-with-hemodynamics-and-functional-capacity-in-therapy-naive-precapillary-pulmonary-hypertension-results-from-a-cohort-study
#13
T M Berghaus, J Kutsch, C Faul, W von Scheidt, M Schwaiblmair
BACKGROUND: N-terminal pro-brain-type natriuretic peptide (NT-proBNP) is currently used as a surrogate marker for disease severity in pulmonary hypertension (PH). However, NT-proBNP tends to have a high variability and may insufficiently correlate with hemodynamics and exercise capacity. METHODS: To investigate the association of NT-proBNP with hemodynamics and cardio-pulmonary exercise testing (CPET) in 84 therapy-naive patients with precapillary PH. RESULTS: NT-proBNP levels were significantly correlated with hemodynamics and CPET parameters except for cardiac index, diffusion capacity, PaO2 at peak exercise, and peak minute ventilation...
December 4, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29201546/neurologists-dealing-with-sickness-certification-experiences-of-problems-and-need-of-competence
#14
Åsa Snöljung, Jenny Kärrholm, Elin Hinas, Kristina Alexanderson
Rationale and Aims: Most studies on physicians' sickness certification practices include general practitioners (GP) while there hardly is any knowledge on this regarding neurologists although neurological diseases often involve work incapacity and need of sick leave. Aim: The aim was to describe experiences among neurologists in Sweden concerning their work with sickness certification of patients. Method: A cross-sectional study of 265 neurologists' responses in a nationwide survey regarding their work with sickness certification of patients was conducted...
November 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29201153/poor-glycaemic-control-is-associated-with-reduced-exercise-performance-and-oxygen-economy-during-cardio-pulmonary-exercise-testing-in-people-with-type-1-diabetes
#15
Othmar Moser, Max L Eckstein, Olivia McCarthy, Rachel Deere, Stephen C Bain, Hanne L Haahr, Eric Zijlstra, Richard M Bracken
Background: To explore the impact of glycaemic control (HbA1c) on functional capacity during cardio-pulmonary exercise testing in people with type 1 diabetes. Methods: Sixty-four individuals with type 1 diabetes (age: 34 ± 8 years; 13 females, HbA1c: 7.8 ± 1% (62 ± 13 mmol/mol), duration of diabetes: 17 ± 9 years) performed a cardio-pulmonary cycle ergometer exercise test until volitional exhaustion. Stepwise linear regression was used to explore relationships between HbA1c and cardio-respiratory data with p ≤ 0...
2017: Diabetology & Metabolic Syndrome
https://www.readbyqxmd.com/read/29198868/an-interagency-registry-for-mechanically-assisted-circulatory-support-intermacs-analysis-of-hospitalization-functional-status-and-mortality-after-mechanical-circulatory-support-in-adults-with-congenital-heart-disease
#16
Ari Cedars, Christina Vanderpluym, Devin Koehl, Ryan Cantor, Shelby Kutty, James K Kirklin
BACKGROUND: Adult congenital heart disease (ACHD) prevalence is increasing worldwide, with advanced heart failure (HF) as a leading cause of death. Limited data are available on durable mechanical circulatory support (MCS) in ACHD patients. METHODS: ACHD patients from the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) database were identified and propensity matched with non-ACHD patients using risk factors from the INTERMACS Seventh Annual Report...
November 17, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29197960/sarcopenia-during-neoadjuvant-therapy-for-oesophageal-cancer-characterising-the-impact-on-muscle-strength-and-physical-performance
#17
Emer M Guinan, S L Doyle, A E Bennett, L O'Neill, J Gannon, J A Elliott, J O'Sullivan, J V Reynolds, J Hussey
PURPOSE: Preoperative chemo(radio)therapy for oesophageal cancer (OC) may have an attritional impact on body composition and functional status, impacting postoperative outcome. Physical decline with skeletal muscle loss has not been previously characterised in OC and may be amenable to physical rehabilitation. This study characterises skeletal muscle mass and physical performance from diagnosis to post-neoadjuvant therapy in patients undergoing preoperative chemo(radio)therapy for OC...
December 2, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29197929/transdiagnostic-symptom-clusters-and-associations-with-brain-behavior-and-daily-function-in-mood-anxiety-and-trauma-disorders
#18
Katherine A Grisanzio, Andrea N Goldstein-Piekarski, Michelle Yuyun Wang, Abdullah P Rashed Ahmed, Zoe Samara, Leanne M Williams
Importance: The symptoms that define mood, anxiety, and trauma disorders are highly overlapping across disorders and heterogeneous within disorders. It is unknown whether coherent subtypes exist that span multiple diagnoses and are expressed functionally (in underlying cognition and brain function) and clinically (in daily function). The identification of cohesive subtypes would help disentangle the symptom overlap in our current diagnoses and serve as a tool for tailoring treatment choices...
December 3, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/29197203/positive-impact-of-prescribed-physical-activity-on-symptoms-of-schizophrenia-randomized-clinical-trial
#19
Dorde Curcic, Tamara Stojmenovic, Slavica Djukic-Dejanovic, Nenad Dikic, Milica Vesic-Vukasinovic, Nenad Radivojevic, Marija Andjelkovic, Milica Borovcanin, Gorica Djokic
BACKGROUND: The purpose of this study was to examine functional capacity of cardio-respiratory system in patients with schizophrenia, and to evaluate the effects of 12 weeks prescribed physical activity on aerobic capacity and symptoms of schizophrenia. SUBJECTS AND METHODS: Study involved 80 hospitalized patients with any of the subtypes of schizophrenia (42 men, 38 women). They were divided into two groups: exercise and control group, both with 40 patients. Maximal aerobic capacity (VO2 max) as an indicator of cardiovascular fitness has been obtained by cardiopulmonary stress test on a treadmill...
December 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/29196226/clinical-assessment-of-patients-with-isolated-hip-fractures-associated-with-an-upper-limb-fracture
#20
J Gómez-Álvarez, S González-Escobar, E Gil-Garay
INTRODUCTION: Some patients with a hip fracture also present a concomitant upper limb fracture. We want to know whether these patients have a worse functional level and whether they have any differences in various clinical parameters compared with patients with an isolated hip fracture. MATERIAL AND METHODS: We retrospectively reviewed 1061 discharge reports from the Orthogeriatrics Unit. We collected information on several clinical parameters of the fractures. Subsequently, we performed a statistical analysis of the data by comparing the associated fracture group with the isolated fracture group...
November 28, 2017: Revista Española de Cirugía Ortopédica y Traumatología
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