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"Physical function"

Emma Dargie, Ronald R Holden, Caroline F Pukall
Millions suffer from chronic vulvar pain (ie, vulvodynia). Vulvodynia represents the intersection of 2 difficult subjects for health care professionals to tackle: sexuality and chronic pain. Those with chronic vulvar pain are often uncomfortable seeking help, and many who do so fail to receive proper diagnoses. The current research developed a multidimensional assessment questionnaire, the Vulvar Pain Assessment Questionnaire (VPAQ) inventory, to assist in the assessment and diagnosis of those with vulvar pain...
August 1, 2016: Pain
Nicoline Callesen Do, Anna Lilja Secher, Per Cramon, Lene Ringholm, Torquil Watt, Peter Damm, Elisabeth Reinhardt Mathiesen
INTRODUCTION: To explore changes in health-related quality of life, anxiety and depression symptoms during pregnancy in women with pregestational diabetes. MATERIAL AND METHODS: An observational cohort study including 137 pregnant women with pregestational diabetes (110 with type 1 and 27 with type 2). To evaluate changes from early to late pregnancy, the internationally validated questionnaires 36-Item Short-Form Health Survey (SF-36) and Hospital Anxiety and Depression Scale (HADS), were completed at 8 and 33 gestational weeks...
October 25, 2016: Acta Obstetricia et Gynecologica Scandinavica
Richard Bogan, Todd Swick, Mortimer Mamelak, Ruzica Kovacevic-Ristanovic, Chinglin Lai, Jed Black, Kathleen F Villa, Jacques Montplaisir
INTRODUCTION: The present post hoc analysis was designed to evaluate health-related quality of life (HRQoL) using the 36-item Short Form Health Status Survey (SF-36) during an 8-week trial of sodium oxybate (SXB). METHODS: SF-36 was assessed in a phase 3 placebo-controlled trial in patients with narcolepsy (N = 228) randomized to placebo or SXB in doses of 4.5, 6, or 9 g nightly for 8 weeks. Changes from baseline in SF-36 (last observation carried forward) were compared between SXB and placebo, and effect sizes (ES) were estimated...
October 24, 2016: Neurology and Therapy
Myung-Rae Cho, Won Kee Choi, Jae Jung Kim
Instability and dislocation after total hip arthroplasty are the most common causes of revisions and major complications for failure of inserted prostheses, leading to a reduction in quality of life. Because the use of artificial femoral head sizes smaller than patient's own size is the important cause for dislocation, the use of large femoral head have increased. Femoral head sizes greater than 32 mm offer multiple advantages in physical function and activity levels of patients by improving hip stability, decreasing dislocation rate and increasing range of motion...
September 2016: Hip Pelvis
Osvaldo P Almeida, Graeme J Hankey, Bu B Yeap, Jonathan Golledge, Keith D Hill, Leon Flicker
BACKGROUND: Older adults with depression have increased risk of frailty and death. OBJECTIVE: To determine if history of depression hinders future physical and functional capacity. DESIGN, SETTING, AND PARTICIPANTS: Prospective longitudinal cohort study of 1148 men aged 70-87 years who were living in the Perth metropolitan community in 2001-2004 and completed a follow-up assessment of physical and functional capacity in 2011-2012. MAIN OUTCOME AND MEASURES: Outcomes were collected in 2011-2012 and included 4 measures of physical function (timed up-and-go, timed sit-to-stand, functional reach, and step test) and the assessment of basic (activities of daily living) and instrumental activities of daily living...
October 21, 2016: Journal of the American Medical Directors Association
Karlyn A Edwards, Kevin A Alschuler, Dawn M Ehde, Samuel L Battalio, Mark P Jensen
OBJECTIVE: To (1) determine if resilience exhibits similar stability across time as depression, fatigue, and sleep quality, and (2) determine if changes in resilience over a period of one year are associated with changes in depression, fatigue, sleep quality and physical function over this same time period. DESIGN: Observational longitudinal survey study with measures administered two times, one year apart. SETTING: A community-based population sample...
October 21, 2016: Archives of Physical Medicine and Rehabilitation
Balázs Ligeti, Ottilia Menyhárt, Ingrid Petrič, Balázs Győrffy, Sándor Pongor
BACKGROUND: Biomedical sciences use a variety of data sources on drug molecules, genes, proteins, diseases and scientific publications etc. This system can be best pictured as a giant data-network linked together by physical, functional, logical and similarity relationships. A new hypothesis or discovery can be considered as a new link that can be deduced from the existing connections. For instance, interactions of two pharmacons - if not already known - represent a testable novel hypothesis...
October 21, 2016: Current Pharmaceutical Design
Joan C Lo, Gerald J Beck, George A Kaysen, Christopher T Chan, Alan S Kliger, Michael V Rocco, Glenn M Chertow
Introduction End-stage renal disease is associated with elevations in circulating prolactin concentrations, but the association of prolactin concentrations with intermediate health outcomes and the effects of hemodialysis frequency on changes in serum prolactin have not been examined. Methods The FHN Daily and Nocturnal Dialysis Trials compared the effects of conventional thrice weekly hemodialysis with in-center daily hemodialysis (6 days/week) and nocturnal home hemodialysis (6 nights/week) over 12 months and obtained measures of health-related quality of life, self-reported physical function, mental health and cognition...
October 23, 2016: Hemodialysis International
Joan A Vaccaro, Fatma G Huffman
Background. Approximately 17% of children aged 6-11 years were classified as obese in the United States. Obesity adversely affects physical functioning and leads to reduced quality of life. Heart function for overweight and obese children has not been reported. Methods. Data for this study were from NHANES National Youth Fitness Survey (NNYFS) conducted in conjunction with the National Health and Nutrition Examination Survey (NHANES) in 2012. This study used data from children aged 6-12 (N = 732) that had the cardiorespiratory endurance measure, body mass index for age and sex, and dietary data (N = 682)...
2016: Journal of Obesity
Michael A Kraus, Richard J Fluck, Eric D Weinhandl, Sheru Kansal, Michael Copland, Paul Komenda, Fredric O Finkelstein
Diminished health-related quality of life (HRQoL) is common in dialysis patients and associated with increased risks for morbidity and mortality. Patients may present limitations in both physical and mental HRQoL. Poor physical HRQoL may be defined by limited physical function, role limitations due to physical health, dissatisfaction with physical ability, and impaired mobility. Sleep disorders such as obstructive sleep apnea, restless legs, and fatigue are typical manifestations of poor physical HRQoL in dialysis patients...
November 2016: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
Racquel E Kohler, Jared Tomlinson, Tiyamike Eletima Chilunjika, Sven Young, Mina Hosseinipour, Clara N Lee
PURPOSE: Low- and middle-income countries face a disproportionate burden of death and disability from injuries, many of which are due to road traffic accidents or falls. Lower extremity injuries in particular have implications not only for physical disabilities affecting work and school performance, but also for quality of life (QOL) of the individual. This qualitative study explores the psychosocial impact and QOL changes due to lower extremity injuries among trauma patients in central Malawi...
October 22, 2016: Quality of Life Research
Ada Wai Tung Fung, Wai-Chi Chan, Corine Sau-Man Wong, Eric Yu-Hai Chen, Roger Man-Kin Ng, Edwin Ho-Ming Lee, Wing-Chung Chang, Se-Fong Hung, Eric Fuk-Chi Cheung, Pak-Chung Sham, Helen Fung-Kum Chiu, Ming Lam, Tin-Po Chiang, Jim van Os, Joseph Tak-Fai Lau, Glyn Lewis, Paul Bebbington, Linda Chiu Wa Lam
BACKGROUND: Anxiety disorders are prevalent yet under-recognized in late life. We examined the prevalence of anxiety disorders in a representative sample of community dwelling older adults in Hong Kong. METHOD: Data on 1,158 non-demented respondents aged 60-75 years were extracted from the Hong Kong Mental Morbidity survey (HKMMS). Anxiety was assessed with the revised Clinical Interview Schedule (CIS-R). RESULT: One hundred and thirty-seven respondents (11...
October 21, 2016: International Psychogeriatrics
Kumi Shidara, Ayako Nakajima, Eisuke Inoue, Daisuke Hoshi, Naoki Sugimoto, Yohei Seto, Eiichi Tanaka, Katsunori Ikari, Atsuo Taniguchi, Hisashi Yamanaka
OBJECTIVE: To validate the minimally important difference (MID) of physical function using the Japanese version of the Health Assessment Questionnaire (J-HAQ) in a cohort of rheumatoid arthritis (RA). METHODS: Patients who participated in a cohort study in both October 2008 and April 2009 were analyzed. Patients self-rated their change in overall status over 6 months using a 5-point Likert scale ("much better", "somewhat better", "same", "somewhat worse", or "much worse")...
October 21, 2016: Modern Rheumatology
Shosuke Satake, Hidenori Arai
PURPOSE OF REVIEW: Many frailty screening instruments have been proposed due to the lack of consensus on a unified operational definition of frailty. This review reports on recent frailty screening tools in addition to revisiting the frailty concept. RECENT FINDINGS: Although there are two representative frailty models, both have issues that prevent them from being implemented in clinical settings despite their remarkable advantages. Due to their different characteristics, these models are thought to be complementary rather than substitutive...
October 18, 2016: Current Opinion in Clinical Nutrition and Metabolic Care
Theodore Pincus
RAPID3 (routine assessment of patient index data) is an index found within a multi-dimensional health assessment questionnaire (MDHAQ) for routine clinical care, composed only of 3 self-report scores for physical function, pain, and patient global estimate, each scored 0-10, for a total of 0-30. RAPID3 is correlated significantly with DAS28 (Disease Activity Score) and CDAI (Clinical Disease Activity Index), and distinguishes active from control treatments as efficiently as these indices in clinical trials involving adalimumab, abatacept, certolizumab, infliximab, and rituximab...
September 2016: Clinical and Experimental Rheumatology
M Henze, H Alfonso, L Flicker, J George, S A Paul Chubb, G J Hankey, O P Almeida, J Golledge, P E Norman, B B Yeap
AIMS: To investigate behavioural, physical and biochemical characteristics associated with diabetes in the oldest age group of elderly men. METHODS: We conducted a cross-sectional analysis of community-dwelling men aged 79-97 years from Perth, Western Australia. Lifestyle behaviours, self-rated health, physical function, and fasting glucose and HbA1c levels were assessed. RESULTS: Of 1426 men, 315 had diabetes (22%). Men with diabetes were of similar age to men without (84...
October 20, 2016: Diabetic Medicine: a Journal of the British Diabetic Association
Babak Nakhostin-Roohi, Faegheh Khoshkhahesh, Shahab Bohlooli
OBJECTIVE: The main purpose of this study was to evaluate the effects of virgin olive oil phonophoresis on female athletes' anterior knee pain (AKP). MATERIALS AND METHODS: A double blinded randomized clinical trial was conducted. Ninety-three female athletes suffering from AKP voluntarily participated in this study. Patients were randomly assigned into olive oil (n=31), piroxicam (n=31) or base gel phonophoresis (n=31) groups. At the baseline visit, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire was filled by subjects who were then treated with olive oil, piroxicam or pure phonophoresis for 12 sessions...
September 2016: Avicenna Journal of Phytomedicine
H Felix Fischer, Matthias Rose
BACKGROUND: Recently, a growing number of Item-Response Theory (IRT) models has been published, which allow estimation of a common latent variable from data derived by different Patient Reported Outcomes (PROs). When using data from different PROs, direct estimation of the latent variable has some advantages over the use of sum score conversion tables. It requires substantial proficiency in the field of psychometrics to fit such models using contemporary IRT software. We developed a web application ( http://www...
October 19, 2016: BMC Medical Research Methodology
Carol L Hodgson, Alison E Turnbull, Theodore J Iwashyna, Ann Parker, Wesley Davis, Clifton O Bingham, Nicola R Watts, Simon Finfer, Dale M Needham
BACKGROUND: There is increasing interest in measuring the quality of survivorship for patients admitted to the intensive care (ICU) for acute respiratory failure (ARF). However, there is substantial variability in the patient outcomes reported in studies evaluating these patients, with few data on which outcomes are essential to inform clinical practice. PURPOSE: To determine clinicians' perspectives on the outcome domains that should always be reported in studies evaluating ARF survivors after hospital discharge, and to compare findings between the US and Australian perspectives...
October 6, 2016: Physical Therapy
Brian D Gonzalez, Sharon L Manne, Jerod Stapleton, Shannon Myers-Virtue, Melissa Ozga, David Kissane, Carolyn Heckman, Mark Morgan
PURPOSE: The course of quality of life after diagnosis of gynecologic cancer is not well understood. We aimed to identify subgroups of gynecologic cancer patients with distinct trajectories of quality of life outcomes in the 18-month period after diagnosis. We also aimed to determine whether these subgroups could be distinguished by predictors derived from Social-Cognitive Processing Theory. METHODS: Gynecologic cancer patients randomized to usual care as part of a psychological intervention trial (NCT01951807) reported on depressed mood, quality of life, and physical impairment soon after diagnosis and at five additional assessments ending 18 months after baseline...
October 19, 2016: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
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