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Toan Thanh Thi Do, Mai Dinh Le, Thanh Van Nguyen, Bach Xuan Tran, Huong Thi Le, Hinh Duc Nguyen, Long Hoang Nguyen, Cuong Tat Nguyen, Tho Dinh Tran, Carl A Latkin, Roger C M Ho, Melvyn W B Zhang
BACKGROUND: As smartphone becomes increasingly prevalent and affordable, more youths today can own a smartphone device and download applications in various application stores. Smartphone applications have been proven to be useful for youths in various aspects. However, there has been a paucity of data looking into the preferences of Vietnamese youths and adolescents with regards to health-related applications and their receptiveness towards smartphone apps. Therefore, this study aimed to determine the receptiveness and preferences of health-related smartphone applications (mHealth apps) among online Vietnamese youths and adolescents...
June 19, 2018: BMC Public Health
Vo Thi Thuong Lan, Ho Van Son, Vu Lan Trang, Nguyen Thu Trang, Nguyen Thi Phuong, Nguyen Linh Toan, Pham Anh Thuy Duong
The three genes encoding small non‑coding microRNA (miR)34a, MIR34b and MIR34c act as tumor‑suppressor genes. Their aberrant expressions regulated by DNA methylation have been frequently found in various types of cancer. In the present study, the DNA promoter methylation profiles of the MIR34 gene family were analyzed using the methylation specific polymerase chain reaction in order to clarify their association with breast and lung cancer, non‑cancerous or normal adjacent tissues. The methylation frequency of MIR34a was significantly higher in breast cancer (49...
June 18, 2018: Molecular Medicine Reports
Nguyen Thi Mai Huong, Nguyen Thi Kim Lien, Ngo Diem Ngoc, Nguyen Thi Phuong Mai, Nguyen Pham Anh Hoa, Le Thanh Hai, Phan Van Chi, Ta Thanh Van, Tran Van Khanh, Nguyen Huy Hoang
BACKGROUND: Wilson disease (OMIM # 277900) is a autosomal recessive disorder characterized by accumulation of copper in liver and brain. The accumulation of copper resulting in oxidative stress and eventually cell death. The disease has an onset in a childhood and result in a significant neurological impairment or require lifelong treatment. Another serious consequence of the disease is the development of liver damage and acute liver failure leading to liver transplant. The disorder is caused by mutations in the ATP7B gene, encoding a P-type copper transporting ATPase...
June 18, 2018: BMC Medical Genetics
Jill Murphy, Pham Thi Oanh, Charles H Goldsmith, Wayne Jones, Vu Cong Nguyen
INTRODUCTION: Although depression is a major contributor to the global burden of disease, services remain scarce in many low- and middle-income countries. In Vietnam, depression services are limited, and the government has recently prioritized primary care and community-based service integration. We conducted a pilot study in 2 districts of Hanoi to test the feasibility of (a) introducing a supported self-management (SSM) intervention for adult depression in primary care in Vietnam, and (b) conducting a randomized controlled trial (RCT) to test the effectiveness of the intervention...
June 2018: Families, Systems & Health: the Journal of Collaborative Family Healthcare
Tav Pham
OBJECTIVE: To investigate the association between periodontal disease severity and metabolic syndrome (MetS) in a group of Vietnamese patients. METHODS: A total of 412 participants (114 males, 298 females, average age 57.8 ± 5.7 years) including 206 patients with MetS and 206 participants without MetS were selected for this study. Information on sociodemographic characteristics, dental behaviours and smoking status was collected from a self-administrated questionnaire...
June 14, 2018: International Journal of Dental Hygiene
Ton That Huu Dat, Georg Steinert, Nguyen Thi Kim Cuc, Hauke Smidt, Detmer Sipkema
Sponge-associated prokaryotic diversity has been studied from a wide range of marine environments across the globe. However, for certain regions, e.g., Vietnam, Thailand, Cambodia, and Singapore, an overview of the sponge-associated prokaryotic communities is still pending. In this study we characterized the prokaryotic communities from 27 specimens, comprising 18 marine sponge species, sampled from the central coastal region of Vietnam. Illumina MiSeq sequencing of 16S ribosomal RNA (rRNA) gene fragments was used to investigate sponge-associated bacterial and archaeal diversity...
2018: PeerJ
Jana Olak, Minh Son Nguyen, Thuy Trang Nguyen, Bui Bao Tien Nguyen, Mare Saag
Objective: The study aims to investigate how mothers' oral health behaviour and perception thereof influence the dental health in their children. Methods: A total of 556 Vietnamese mother-child pairs participated in the current study. Mothers self-reported their oral status and oral health behaviour and perception. Dental caries of the children were examined using the index of decayed, missing, and filled teeth. The Dental Anxiety Scale instrument was used to assess the dental anxiety level in mothers and children...
June 2018: EPMA Journal
Quoc Cuong Tran, Merrilyn Banks, Mary Hannan-Jones, Thi Ngoc Diep Do, Danielle Gallegos
BACKGROUND/OBJECTIVES: Hospital malnutrition is a common problem worldwide. This study aims to assess the validity of widely used nutritional screening tools for hospitalized adults in acute care settings in Ho Chi Minh City, Vietnam. SUBJECTS/METHODS: Participants in this study were 693 adult patients from six general public hospitals, in a multi-center survey undertaken in April and May, 2016. The criterion validity of the Malnutrition Screening Tool (MST), Malnutrition Universal Screening Tool (MUST), Nutrition Risk Screening (NRS-2002) and Mini Nutrition Assessment-Short Form (MNA-SF), modified MST (MST combined with low BMI), and BMI as independent tools were assessed using Subjective Global Assessment (SGA) or low BMI (<18...
June 12, 2018: European Journal of Clinical Nutrition
Van N B Nguyen, Helen Forbes, Mohammadreza Mohebbi, Maxine Duke
AIMS: To describe how clinical nurse educators in Vietnam are prepared for their role; to identify which preparation strategies assist development of confidence in clinical teaching; and to measure the effect of educational qualifications and professional background on perceived confidence levels. BACKGROUND: The quality of clinical teaching can directly affect the quality of the student learning experience. The role of the clinical educator is complex and dynamic and requires a period of adjustment for successful role transition to occur...
June 12, 2018: Journal of Advanced Nursing
Gopal K Singh, Mohammad Siahpush, Lihua Liu, Michelle Allender
This study examines racial/ethnic, nativity, and sociodemographic variations in the prevalence of maternal hypertension in the United States. The 2014-2015 national birth cohort data ( N = 7,966,573) were modeled by logistic regression to derive unadjusted and adjusted differentials in maternal hypertension consisting of both pregnancy-related hypertension and chronic hypertension. Substantial racial/ethnic differences existed, with prevalence of maternal hypertension ranging from 2.2% for Chinese and 2.9% for Vietnamese women to 8...
2018: International Journal of Hypertension
Pham Duc Thinh, Bui Minh Ly, Roza V Usoltseva, Natalia M Shevchenko, Anton B Rasin, Stanislav D Anastyuk, Olesya S Malyarenko, Tatiana N Zvyagintseva, Pham Trung San, Svetlana P Ermakova
In the present study, three sulfated polysaccharides, two fractions of fucosylated chondroitin sulfates, and one sulfated fucan were isolated from the body wall of the Vietnamese sea cucumber Stichopus variegatus. The structure of the sulfated fucan fraction SvF3 from S. variegatus was investigated for the first time. According to NMR spectroscopy data, the sulfated fucan SvF3 contained 1,2- and 1,3-linked α-l-fucopyranose residues. Sulfate groups were found at the 2 and/or 4 positions. The structural analysis of fucoidan was assisted by tandem mass spectrometry; the recently-developed technique of autohydrolysis in heavy‑oxygen water for the obtaining of selectively labeled fucoidan fragments was applied...
June 6, 2018: International Journal of Biological Macromolecules
YoonJee Hong, Kyung Seok Kim, Junpei Kimura, Kaarina Kauhala, Inna Voloshina, Mikhail S Goncharuk, Li Yu, Ya-Ping Zhang, Mariko Sashika, Hang Lee, Mi-Sook Min
The raccoon dog (Nyctereutes procyonoides) is endemic to East Asia but has been introduced in Europe. Its high adaptability enabled its rapid colonization of European countries, where population growth has been raising concerns regarding ecosystem disturbance and the spread of zoonotic diseases. The genetic diversity and structure of endemic, source, and introduced populations from seven locations across South Korea, China, Russian Far East, Finland (spread to Finland after introduction to European part of Russia from Russian Far East), Vietnam, and Japan (Honshu and Hokkaido) were examined based on 16 microsatellite loci...
June 2018: Zoological Science
Trinh Tat Cuong, Giang Huy Diem, Tran Trung Doan, Nguyen Quang Huy, Nguyen Phuong, Hoang The Hung
Wedelolactone is known to have biological activities such as anti-inflammation hepatitis, anti-hepatotoxic activity, and trypsin inhibitory effect. However, up to date, there has not been any deep study on the role of wedelolactone for zymosan-induced signaling pathways in the process of regulating the excessive inflammatory responses in host. Here, we demonstrated that wedelolactone plays an essential role for regulation of zymosan-induced inflammatory responses in murine bone marrow-derived macrophages (BMDMs)...
2018: Iranian Journal of Pharmaceutical Research: IJPR
Claudio I Perez, Sunee Chansangpetch, Andy Thai, Anh-Hien Nguyen, Anwell Nguyen, Marta Mora, Ngoc Nguyen, Shan C Lin
PURPOSE: Evaluate the distribution and the color probability codes of the peripapillary retinal nerve fiber layer (RNFL) and macular ganglion cell-inner plexiform layer (GCIPL) thickness in a healthy Vietnamese population and compare them with the original color-codes provided by the Cirrus spectral domain OCT. METHODS: Cross-sectional study. We recruited non-glaucomatous Vietnamese subjects and constructed a normative database for peripapillary RNFL and macular GCIPL thickness...
June 5, 2018: Journal of Glaucoma
Nguyen Viet Hung, Phan Thi Hang, Victor D Rosenthal, Le Thi Anh Thu, Le Thi Thu Nguyet, Ngo Quy Chau, Truong Anh Thu, Dinh Pham Phuong Anh, Tran Thi My Hanh, Tran Thi Thuy Hang, Dang Thi Van Trang, Nguyen Phuc Tien, Vo Thi Hong Thoa, Đao Quang Minh
OBJECTIVE: The aim of the study was to report the results of the International Nosocomial Infection Control Consortium (INICC) study conducted from May 2008 to March 2015. METHODS: A device-associated healthcare-acquired infection surveillance study in three adult intensive care units (ICUs) and 1 neonatal ICU from 4 hospitals in Vietnam using U.S. the Centers for Disease Control and Prevention's National Healthcare Safety Network (CDC/NHSN) definitions and criteria as well as INICC methods...
June 4, 2018: Journal of Patient Safety
M T H Le, S Holton, M Kirkman, J Fisher
Background: The experiences of and reflections on interpersonal violence and victimisation among adolescents living in low- and middle-income countries are poorly understood. The aim was to describe Vietnamese adolescents' reflections on their experiences of victimisation. Method: A self-completed, cross-sectional survey investigating exposure to violence among high school students in Hanoi, Vietnam was conducted during 2013-2014. The last section invited participants to write about any of the matters covered in the questionnaire...
2018: Global Mental Health
Nguyen Thi Phuong Oanh, Teruhiko Kido, Seijiro Honma, Yuko Oyama, Le Thai Anh, Hoang Duc Phuc, Nguyen Hoang Viet, Ho Dung Manh, Rie Okamoto, Hideaki Nakagawa, Shoji F Nakayama, Dang Duc Nhu, Dao Van Tung, Vo Van Chi, Nguyen Hung Minh, Ngo Van Toan
Dioxins have been suspected to be potential substances causing endocrine disruptions in humans. We are conducting the research in one of three dioxin exposure areas (hotspots) in Vietnam. We previously reported that the salivary dehydroepiandrosterone (DHEA) level decreased in 3-year-old Vietnamese children and that it was significantly inversely correlated with polychlorinated dibenzodioxin/dibenzofuran levels in their mother's breast milk. In this study, we investigated the influence of exposure to dioxin on steroid hormone biosynthesis in the same children when they reached 5 years of age, focusing on androgens...
June 1, 2018: Science of the Total Environment
Van Thai Nguyen, Toai Nguyen, Triin Jagomägi
OBJECTIVES: The study aimed to compare nasolabial aesthetics of patients with unilateral cleft lip and palate (UCLP) treated in Vietnam and Estonia using three rating methods: five-point aesthetic index, a visual analogue scale (VAS), and reference scores method. METHODS: A total of 56 patients with repaired UCLP (23 from Vietnam and 33 from Estonia) were included in this cross-sectional study. Patients' facial and profile photographs were cropped to reveal the nasolabial region and coded...
May 18, 2018: Journal of Cranio-maxillo-facial Surgery
Naoki Kodama, Thai Van Loc, Phan Thanh Hai, Nguyen Van Cong, Shinsuke Katsuhara, Satoshi Kasai, Aziz Sheikh
OBJECTIVE: To assess the effectiveness of bone suppression imaging (BSI) in the diagnosis of tuberculosis from chest radiographs (CXRs) in Vietnam. MATERIALS AND METHODS: A total of 97 images (50 tuberculosis and 47 normal) comprised the dataset for this observer study with unanimous consensus of a panel of 3 expert radiologists. The participants were 9 Vietnamese radiologists (6 chest radiologists and 3 non-chest radiologists). Participants recorded their confidence levels regarding the presence of tuberculosis after reading a standard chest radiograph directly first and then after BSI processing...
May 30, 2018: Clinical Imaging
Thi Thuy Hien Tran, Nathalie Vallée, Lionel Granjon
A variety of studies have shown differences between phonetic features of consonants according to their prosodic and/or syllable (onset vs. coda) positions. However, differences are not always found, and interactions between the various factors involved are complex and not well understood. Our study compares acoustical characteristics of coda consonants in Vietnamese taking into account their position within words. Traditionally described as monosyllabic, Vietnamese is partially polysyllabic at the lexical level...
May 28, 2018: Phonetica
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