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https://www.readbyqxmd.com/read/28433992/the-aachen-minipig-phenotype-genotype-hematological-and-biochemical-characterization-and-comparison-to-the-g%C3%A3-ttingen-minipig
#1
Kerstin Pawlowsky, Lisa Ernst, Julia Steitz, Thaddäus Stopinski, Babette Kögel, Anna Henger, Reinhart Kluge, René Tolba
BACKGROUND: The pig is one of the most frequently used large animal models for biomedical research, especially in the field of translational research and surgical models. While standard livestock breeds are used in short-term and acute studies, minipig breeds are the preferred breeds in long-term and chronic studies due to their limited growth and body weight. OBJECTIVE: In consideration of the 3R principle (refinement, reduction, replacement) and the increasing demand, the aim of this study was to generate a new, robust, non-specific-pathogen-free minipig breed, the Aachen minipig...
April 22, 2017: European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
https://www.readbyqxmd.com/read/28429916/opportunities-and-barriers-to-public-health-nutrition-education-in-vietnamese-universities
#2
Quynh Th Pham, Anthony Worsley, Mark Lawrence, Bernie Marshall
BACKGROUND AND OBJECTIVES: A core challenge for low- and middle-income countries (LMICs) in combating the negative effects of the nutrition transition is to implement appropriate prevention strategies to halt the increasing prevalence of obesity and non-communicable diseases (NCDs), against a background of prevailing under nutrition. There have been several proposals for the enhancement of university nutrition education for future health and related professionals who are expected to communicate knowledge of health risks to the broad community...
May 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28429791/social-and-anthropometric-factors-explaining-racial-ethnical-differences-in-birth-weight-in-the-united-states
#3
Naho Morisaki, Ichiro Kawachi, Emily Oken, Takeo Fujiwara
Though disparities in birth weight by race/ethnicity have been extensively reported in the United States, few studies have systematically investigated factors attributing to its variability. For 10,638,415 singleton infants born during 2009-2012 in the United States, we examined birth weight differences among 14 races and ethnicities (non-Hispanic white, non-Hispanic Black, American Indian, Asian Indian, Chinese, Filipino, Japanese, Korean, Vietnamese, Hawaiian, Guamanian, Mexican, Puerto Rican and Cuban), after sequentially adjusting for maternal, socio-economic and behavioral factors...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28426321/hansae-vietnam-s-garment-factory-latest-example-of-how-corporate-social-responsibility-has-failed-to-protect-workers
#4
Garrett Brown
A Korean-operated garment factory complex in Vietnam was subject to 26 separate corporate social responsibility (CSR) audits in 2015. However, thorough inspections by two other non-governmental organizations in 2016 found numerous violations of Vietnamese occupational health and safety and labor laws as well as violations of the corporate codes of conduct of the international clothing brands which source apparel from the facility. The 2016 investigations indicate the lack of efficacy of the 2015 CSR audits and call into question whether voluntary CSR programs and audits by for-profit CSR monitoring companies can effectively protect the health, safety and legal rights of workers in global supply chains...
April 20, 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/28424783/peptide-fraction-poh2-exerts-antiadipogenic-activity-through-inhibition-of-c-ebp-%C3%AE-and-ppar-%C3%AE-expression-in-3t3-l1-adipocytes
#5
Thi Tuyet Nhung Nguyen, Thi Thu Ha, Thi Hoa Nguyen, Thi Hien Vu, Nam Hai Truong, Hoang Ha Chu, Dong Van Quyen
Many studies have comprehensively examined the venom of Ophiophagus hannah snake. Its venom comprises different compounds exhibiting a wide range of pharmacological activities. In this investigation, four peptide fractions (PFs), ranging from 3 kDa to 10 kDa, isolated from the Vietnamese snake venom of O. hannah were separated by HPLC and investigated for their inhibitory activity on adipogenesis in 3T3-L1 adipocytes. The most effective PF was then further purified, generating two peptides, pOh1 and pOh2...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28424257/an-animal-source-food-supplement-increases-micronutrient-intakes-and-iron-status-among-reproductive-age-women-in-rural-vietnam
#6
Andrew G Hall, Tu Ngu, Hoang T Nga, Phi N Quyen, Pham T Hong Anh, Janet C King
Background: Few studies have examined the impact of local animal-source foods (ASFs) on the nutritional status of reproductive-age women in developing countries.Objective: We hypothesized that a midmorning snack of local ASF for 6 mo would reduce dietary micronutrient deficiencies [usual intake less than the estimated average requirement (EAR)] and improve blood biomarkers of iron, zinc, and vitamins A and B-12 status among nonpregnant, reproductive-age women in rural Vietnam.Methods: One hundred seventeen women, 18-30 y old, were randomly assigned to receive either an ASF (mean: 144 kcal, 8...
April 19, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28421816/cytotoxic-steroid-derivatives-from-the-vietnamese-soft-coral-sinularia-brassica
#7
Hong Hanh Thi Tran, Phong Nguyen Viet, Thanh Nguyen Van, Huong Thu Tran, Cuong Nguyen Xuan, Nam Nguyen Hoai, Thung Do Cong, Kiem Phan Van, Minh Chau Van
Using various chromatographic separations, six ergostane-type steroids, including one new compound sinubrassione (1), and two pregnene-type steroid glycosides, including one new compound sinubrassioside (7), were isolated from methanol extract of the Vietnamese soft coral Sinularia brassica. The structure elucidation was confirmed by spectroscopic methods including 1D, 2D NMR and HR-ESI-MS. The cytotoxic activities of all the isolated compounds against three human cancer cell lines were also evaluated using MTT-based colorimetric assays...
April 19, 2017: Journal of Asian Natural Products Research
https://www.readbyqxmd.com/read/28420846/intrathecal-isoniazid-for-refractory-tuberculous-meningitis-with-cerebral-infarction
#8
Yuko Nakatani, Yutaka Suto, Kazuki Fukuma, Mika Yamawaki, Ryoichi Sakata, Shotaro Takahashi, Hiroyuki Nakayasu, Kenji Nakashima
A 30-year-old Vietnamese woman, about 19 weeks pregnant, was admitted for acute cerebral infarction with stenosis of the left middle cerebral artery (LMCA), tuberculous meningitis, and miliary tuberculosis. Treatment with heparin, quadruple anti-tuberculosis therapy, and dexamethasone afforded prompt symptomatic improvement. However, she delivered a stillbirth, after which there was recurrence of acute cerebral infarction with LMCA occlusion, sinus thrombosis, and cranial base inflammation. A thrice-weekly 100 mg dose of intrathecal isoniazid (INH) improved the signs of meningeal inflammation...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28420377/the-association-between-child-maltreatment-and-emotional-cognitive-and-physical-health-functioning-in-vietnam
#9
Nhu K Tran, Sheila R Van Berkel, Marinus H van IJzendoorn, Lenneke R A Alink
BACKGROUND: There is a paucity of research on correlates of child maltreatment in limited-resource countries with a relatively high tolerance of harsh discipline. This Vietnamese study aimed to investigate associations between different types of child maltreatment and child emotional, cognitive, and physical health functioning as well as moderation effects of gender and ethnicity. METHODS: This cross-sectional study was conducted with 1851 randomly selected students aged 12-17 years...
April 19, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28419315/clinical-parameters-routine-inflammatory-markers-and-lta4h-genotype-as-predictors-of-mortality-among-608-patients-with-tuberculous-meningitis-in-indonesia
#10
Arjan van Laarhoven, Sofiati Dian, Carolien Ruesen, Ela Hayati, Michelle S M A Damen, Jessi Annisa, Lidya Chaidir, Rovina Ruslami, Tri Hanggono Achmad, Mihai G Netea, Bachti Alisjahbana, Ahmad Rizal Ganiem, Reinout van Crevel
Background.: Damaging inflammation is thought to contribute to the high morbidity and mortality of tuberculous meningitis (TBM), but the link between inflammation and outcome remains unclear. Methods.: We performed prospective clinical and routine laboratory analyses of a cohort of adult patients with TBM in Indonesia. We also examined the LTA4H promoter polymorphism, which predicted cerebrospinal fluid (CSF) leukocyte count and survival of Vietnamese patients with TBM...
April 17, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28413325/the-psychopharmacological-activities-of-vietnamese-ginseng-in-mice-characterization-of-its-psychomotor-sedative-hypnotic-antistress-anxiolytic-and-cognitive-effects
#11
Irene Joy I Dela Peña, Hee Jin Kim, Chrislean Jun Botanas, June Bryan de la Peña, Thi Hong Van Le, Minh Duc Nguyen, Jeong Hill Park, Jae Hoon Cheong
BACKGROUND: Panax vietnamensis Ha et Grushv. or Vietnamese ginseng (VG) is a recently discovered ginseng species. Studies on its chemical constituents have shown that VG is remarkably rich in ginseng saponins, particularly ocotillol saponins. However, the psychopharmacological effects of VG have not been characterized. Thus, in the present study we screened the psychopharmacological activities of VG in mice. METHODS: VG extract (VGE) was orally administered to mice at various dosages to evaluate its psychomotor (open-field and rota-rod tests), sedative-hypnotic (pentobarbital-induced sleeping test), antistress (cold swimming test), anxiolytic (elevated plus-maze test), and cognitive (Y-maze and passive-avoidance tests) effects...
April 2017: Journal of Ginseng Research
https://www.readbyqxmd.com/read/28412653/the-relationship-between-dioxins-exposure-and-risk-of-prostate-cancer-with-steroid-hormone-and-age-in-vietnamese-men
#12
Xian Liang Sun, Teruhiko Kido, Seijiro Honma, Eitetsu Koh, Rie Okamoto, Ho Dung Manh, Shoko Maruzeni, Muneko Nishijo, Hideaki Nakagawa, Takeshi Nakano, Takumi Takasuga, Dang Duc Nhu, Nguyen Ngoc Hung, Le Ke Son
Although Vietnam's massive herbicide exposure in 1960s and 1970s was clearly injurious to health, not all causal relationships have been clarified. We therefore explored associations among dioxins, steroid hormones, age and prostate cancer risk in men. We compared serum levels of dioxin, steroid hormones and prostate specific antigen (PSA) in men aged 56-81years from herbicide-exposed hotspots (n=50) with those from non-sprayed regions (n=48). Mean serum levels of dioxin congeners in the hotspot group were 1...
April 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28409692/validation-and-norming-of-the-intelligibility-in-context-scale-in-northern-viet-nam
#13
Ben Phạm, Sharynne McLeod, Linda J Harrison
Vietnamese is one of the 20 most commonly spoken languages in the world; however, there are no standardised tools to assess Vietnamese children's speech. This study aimed to validate and norm the Vietnamese version of the Intelligibility in Context Scale (ICS-VN). Data were collected from parents of 181 children (aged 2;0-5;11) living in Ha Noi, Northern Viet Nam. The mean ICS-VN score was 4.43 (out of a maximum of 5), indicating that children were 'usually' to 'always' intelligible; however, item-level scores demonstrated significant differences between communication partners...
April 14, 2017: Clinical Linguistics & Phonetics
https://www.readbyqxmd.com/read/28392951/three-novel-mutations-in-the-nphs1-gene-in-vietnamese-patients-with-congenital-nephrotic-syndrome
#14
Thi Kim Lien Nguyen, Van Dem Pham, Thu Huong Nguyen, Trung Kien Pham, Thi Quynh Huong Nguyen, Huy Hoang Nguyen
Congenital nephrotic syndrome, a rare and severe disease, is inherited as an autosomal recessive trait. The disease manifests shortly after birth and occurs predominantly in families of Finnish origin but has now been observed in all countries and races. Mutations in the NPHS1 gene, which encodes nephrin, are the main causes of congenital nephrotic syndrome in patients. In this study, we report the first mutational analysis of the NPHS1 gene in three unrelated children from three different Vietnamese families...
2017: Case Reports in Genetics
https://www.readbyqxmd.com/read/28392247/building-workforce-capacity-to-detect-and-respond-to-child-abuse-and-neglect-cases-a-training-intervention-for-staff-working-in-emergency-settings-in-vietnam
#15
Tara Flemington, Jennifer Fraser
BACKGROUND: Too many children are brought to hospital emergency departments on numerous occasions before they are recognised as victims of child abuse and neglect. For this reason, improving knowledge and response behaviors of emergency staff at all levels is likely to have a significant impact on better outcomes. AIM: An Australian based training programme was the first of its kind to address this issue in a Vietnamese Emergency Department. Titled 'Safe Children Vietnam', the programme aimed to improve knowledge, attitudes and reporting behaviors concerning child abuse in the emergency setting...
April 6, 2017: International Emergency Nursing
https://www.readbyqxmd.com/read/28388853/psychometrically-equivalent-bisyllabic-words-for-speech-recognition-threshold-testing-in-vietnamese
#16
Richard W Harris, David L McPherson, Claire M Hanson, Dennis L Eggett
OBJECTIVE: This study identified, digitally recorded, edited and evaluated 89 bisyllabic Vietnamese words with the goal of identifying homogeneous words that could be used to measure the speech recognition threshold (SRT) in native talkers of Vietnamese. DESIGN: Native male and female talker productions of 89 Vietnamese bisyllabic words were recorded, edited and then presented at intensities ranging from -10 to 20 dBHL. Logistic regression was used to identify the best words for measuring the SRT...
April 7, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28365834/breast-cancer-in-asian-americans-in-california-1988-2013-increasing-incidence-trends-and-recent-data-on-breast-cancer-subtypes
#17
Scarlett Lin Gomez, Julie Von Behren, Meg McKinley, Christina A Clarke, Salma Shariff-Marco, Iona Cheng, Peggy Reynolds, Sally L Glaser
PURPOSE: In contrast to other US racial/ethnic groups, Asian Americans (AA) have experienced steadily increasing breast cancer rates in recent decades. To better understand potential contributors to this increase, we examined incidence trends by age and stage among women from seven AA ethnic groups in California from 1988 to 2013, and incidence patterns by subtype and age at diagnosis for the years 2009 through 2013. METHODS: Joinpoint regression was applied to California Cancer Registry data to calculate annual percentage change (APC) for incidence trends...
April 1, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28362047/the-vietnamese-pig-as-a-translational-animal-model-to-evaluate-tissue-engineered-heart-valves-promising-early-experience
#18
Michele Gallo, Helen Poser, Tomaso Bottio, Antonella Bonetti, Paolo Franci, Filippo Naso, Edward Buratto, Fabio Zanella, Giovanni Perona, Carlo Dal Lin, Roberto Bianco, Michele Spina, Roberto Busetto, Maurizio Marchini, Fulvia Ortolani, Laura Iop, Gino Gerosa
Several animal models are currently used for the surgical implantation of either biologic or biopolymeric scaffolds in order to provide in vivo assessment of tissue-engineered heart valves. The Vietnamese pig (VP) is herein proposed as a suitable recipient to test the function of novel bioengineered valve substitutes, in the reconstruction of the right ventricular outflow tract (RVOT). This review aims to provide a complete and exhaustive panel of physiological parameters and methodological information for preclinical studies of tissue-engineered heart valves in the VP animal model...
March 27, 2017: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/28337353/gastric-duplication-a-rare-cause-of-recurrent-vomiting
#19
Brahmananda Koduri, Katie McHale, Christina Yost, Michael H Goodman, Dennis Hoelzer
Vomiting is a physical finding that can occur at any age but presents the greatest challenge when it is recurrent in a child. The etiology is varied (Sieunarine and Manmohansingh, 1989; Suzuki, 1982), and recurrent vomiting can be a symptom of life threatening medical or surgical emergencies. Early recognition is mandatory for preventing delay in management and potential complications. Gastric duplication is rare and mostly diagnosed in infancy with only a few cases documented in the medical literature presenting in childhood...
2017: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/28327126/characterization-and-mechanisms-of-anti-influenza-virus-metabolites-isolated-from-the-vietnamese-medicinal-plant-polygonum-chinense
#20
Thu Thi Tran, Meehyein Kim, Yejin Jang, Hye Won Lee, Hoa Thi Nguyen, Thanh Ngoc Nguyen, Hae Woong Park, Quang Le Dang, Jin-Cheol Kim
BACKGROUND: Polygonum chinense Linn. is a common medicinal plant in Southeast Asia and has been used in traditional medicine in Vietnam. The plant contains phytochemicals with various biological properties; however, its antiviral effect has not yet been demonstrated. This study was aimed to evaluate the anti-influenza virus activity of crude extracts of P. chinense, to characterize antiviral metabolites therefrom and to investigate their mechanisms of antiviral action. METHODS: The methanol (MeOH) extract and organic solvent layers of P...
March 21, 2017: BMC Complementary and Alternative Medicine
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