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https://www.readbyqxmd.com/read/28109260/changes-in-depressive-symptoms-and-correlates-in-hiv-people-at-an-hoa-clinic-in-ho-chi-minh-city-vietnam
#1
Van-Anh N Huynh, Kien G To, Dung Van Do, Quyen G To, Mai T H Nguyen
BACKGROUND: Understanding of depression among Vietnamese people living with HIV (PLWH) is limited. This longitudinal study examines changes in depressive symptoms and identifies its correlates among people living with HIV under antiretroviral therapy at An Hoa Clinic. METHODS: People living with HIV ≥18 years and undergoing antiretroviral therapy for ≥3 months were eligible. Those at final AIDS stage, too ill, or illiterate were excluded due to their inability to complete the self-administered questionnaire...
January 21, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28104980/novel-caga-elisa-exhibits-enhanced-sensitivity-of-helicobacter-pylori-caga-antibody
#2
Yuichi Matsuo, Yasutoshi Kido, Junko Akada, Seiji Shiota, Tran Thanh Binh, Tran Thi Huyen Trang, Ho D Q Dung, Pham Huu Tung, Tran Dinh Tri, Ngo P Minh Thuan, Le Quang Tam, Bui Chi Nam, Vu Van Khien, Yoshio Yamaoka
AIM: To develop a novel Helicobacter pylori (H. pylori) CagA antibody enzyme-linked immunosorbent assay (ELISA) suitable for detecting serum anti-CagA antibodies with high sensitivity. METHODS: Recombinant East Asian-type CagA protein was purified and immobilized for ELISA. Serum samples from 217 Vietnamese individuals (110 H. pylori-infected and 107 uninfected individuals) were applied. Conventional ELISA from Western-type CagA and our East Asian-type CagA ELISA were evaluated by comparing 38 subjects with the Western-type genotype and 72 subjects with the East Asian-type cagA genotype...
January 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28103914/health-literacy-of-recently-hospitalised-patients-a-cross-sectional-survey-using-the-health-literacy-questionnaire-hlq
#3
Rebecca L Jessup, Richard H Osborne, Alison Beauchamp, Allison Bourne, Rachelle Buchbinder
BACKGROUND: Health literacy is simply defined as an individual's ability to access, understand and use information in ways that promote and maintain good health. Lower health literacy has been found to be associated with increased emergency department presentations and potentially avoidable hospitalisations. This study aimed to determine the health literacy of hospital inpatients, and to examine if associations exist between different dimensions of their health literacy, sociodemographic characteristics and hospital services use...
January 19, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28103726/antibacterial-activities-of-chemical-constituents-from-the-aerial-parts-of-hedyotis-pilulifera
#4
Hoai Thi Nguyen, Duc Viet Ho, Hung Quoc Vo, Anh Tuan Le, Hien Minh Nguyen, Takeshi Kodama, Takuya Ito, Hiroyuki Morita, Ain Raal
CONTEXT: Hedyotis pilulifera (Pit.) T.N. Ninh (Rubiaceae) has been used in Vietnamese ethnomedicine; the methanol extract exhibited antibacterial activity in our preliminary screening. OBJECTIVES: In this study, compounds from H. pilulifera were isolated and their antibacterial activity in vitro was evaluated. MATERIALS AND METHODS: The aerial parts of H. pilulifera (1.4 kg) were extracted with MeOH, suspended in water and ethyl acetate extract was chromatographed on a silica gel column...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28103075/a-community-based-randomized-trial-of-hepatitis-b-screening-among-high-risk-vietnamese-americans
#5
Grace X Ma, Carolyn Y Fang, Brenda Seals, Ziding Feng, Yin Tan, Philip Siu, Ming Chin Yeh, Sarit A Golub, Minhhuyen T Nguyen, Tam Tran, Minqi Wang
OBJECTIVES: To evaluate the effectiveness of a community-based liver cancer prevention program on hepatitis B virus (HBV) screening among low-income, underserved Vietnamese Americans at high risk. METHODS: We conducted a cluster randomized trial involving 36 Vietnamese community-based organizations and 2337 participants in Pennsylvania, New Jersey, and New York City between 2009 and 2014. We randomly assigned 18 community-based organizations to a community-based multilevel HBV screening intervention (n = 1131)...
January 19, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28100912/cryptic-splice-activation-but-not-exon-skipping-is-observed-in-minigene-assays-of-dystrophin-c-9361-1g-a-mutation-identified-by-ngs
#6
Emma Tabe Eko Niba, Atsushi Nishida, Van Khanh Tran, Dung Chi Vu, Masaaki Matsumoto, Hiroyuki Awano, Tomoko Lee, Yasuhiro Takeshima, Hisahide Nishio, Masafumi Matsuo
Next-generation sequencing (NGS) discloses nucleotide changes in the genome. Mutations at splicing regulatory elements are expected to cause splicing errors, such as exon skipping, cryptic splice site activation, partial exon loss or intron retention. In dystrophinopathy patients, prediction of splicing outcomes is essential to determine the phenotype: either severe Duchenne or mild Becker muscular dystrophy, based on the reading frame rule. In a Vietnamese patient, NGS identified a c.9361+1G>A mutation in the dystrophin gene and an additional DNA variation of A>G at +117 bases in intron 64...
January 19, 2017: Journal of Human Genetics
https://www.readbyqxmd.com/read/28100136/barriers-to-access-and-uptake-of-antiretroviral-therapy-among-hiv-positive-men-who-have-sex-with-men-in-hanoi-vietnam-from-hiv-testing-to-treatment
#7
Hao T M Bui, Giang M Le, Anh Q Mai, Iryna Zablotska-Manos, Lisa Maher
Little is known about the experiences of Vietnamese men who have sex with men in accessing HIV testing and treatment. We aimed to explore barriers to access and uptake of antiretroviral therapy (ART) among HIV-positive men who have sex with men in Hanoi. During 2015, we conducted qualitative interviews with 35 participants recruited using snowball sampling based on previous research and social networks. Key individual impediments to ART uptake included inadequate preparation for a positive diagnosis and the dual stigmatisation of homosexuality and HIV and its consequences, leading to fear of disclosure of HIV status...
January 19, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/28093687/maternal-birthplace-is-associated-with-low-birth-weight-within-racial-ethnic-groups
#8
Paige D Wartko, Eva Y Wong, Daniel A Enquobahrie
Introduction While disparities in low birth weight (LBW) incidence by racial/ethnic group are well known, differences in LBW incidence by maternal birthplace within racial/ethnic groups, and particularly, differences after adjustment for pregnancy complications, are less clear. Methods We conducted a population-based study of LBW using 113,760 singleton, live birth records from King County, Washington (2008-2012), a region in the Pacific Northwest with a large immigrant population. Study participants were Asian, non-Hispanic black, Hispanic, Native Hawaiian/Other Pacific Islander (NHOPI), and non-Hispanic white women...
January 16, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/28090404/adolescents-stigma-attitudes-toward-internalizing-and-externalizing-disorders-cultural-influences-and-implications-for-distress-manifestations
#9
Anna S Lau, Sisi Guo, William Tsai, D Julie Nguyen, Hannah T Nguyen, Victoria Ngo, Bahr Weiss
OBJECTIVE: This study examined predictors of stigma attitudes toward common youth emotional behavioral problems to test the hypothesis that interdependent cultural values would be associated with differential stigma towards externalizing versus internalizing disorders. Furthermore, we examined whether problem-specific stigma attitudes would predict adolescent's own self-reported manifestations of distress. METHOD: 1224 Vietnamese American and European American adolescents completed measures of social distance stigma attitudes in response to vignettes depicting youth with internalizing (depression, social anxiety, somatization) and externalizing (alcohol use, aggressive behaviors, delinquency) disorders...
July 2016: Clinical Psychological Science
https://www.readbyqxmd.com/read/28086906/physical-activity-and-nutrition-behaviour-outcomes-of-a-cluster-randomized-controlled-trial-for-adults-with-metabolic-syndrome-in-vietnam
#10
Van Dinh Tran, Andy H Lee, Jonine Jancey, Anthony P James, Peter Howat, Le Thi Phuong Mai
BACKGROUND: Metabolic syndrome is prevalent among Vietnamese adults, especially those aged 50-65 years. This study evaluated the effectiveness of a 6 month community-based lifestyle intervention to increase physical activity levels and improve dietary behaviours for adults with metabolic syndrome in Vietnam. METHODS: Ten communes, involving participants aged 50-65 years with metabolic syndrome, were recruited from Hanam province in northern Vietnam. The communes were randomly allocated to either the intervention (five communes, n = 214) or the control group (five communes, n = 203)...
January 13, 2017: Trials
https://www.readbyqxmd.com/read/28079314/scn1a-gene-mutation-and-adaptive-functioning-in-18-vietnamese-children-with-dravet-syndrome
#11
Thi Thu Hang Do, Diem My Vu, Thi Thuy Kieu Huynh, Thi Khanh Van Le, Eun Hwa Sohn, Thieu Mai Thao Le, Huu Hao Ha, Chi Bao Bui
BACKGROUND AND PURPOSE: Dravet syndrome is a rare and severe type of epilepsy in infants. The heterogeneity in the overall intellectual disability that these patients suffer from has been attributed to differences in genetic background and epilepsy severity. METHODS: Eighteen Vietnamese children diagnosed with Dravet syndrome were included in this study. SCN1A variants were screened by direct sequencing and multiplex ligation-dependent probe amplification. Adaptive functioning was assessed in all patients using the Vietnamese version of the Vineland Adaptive Behavior Scales, and the results were analyzed relative to the SCN1A variants and epilepsy severity...
January 2017: Journal of Clinical Neurology
https://www.readbyqxmd.com/read/28078358/major-histocompatibility-complex-haplotyping-and-long-amplicon-allele-discovery-in-cynomolgus-macaques-from-chinese-breeding-facilities
#12
Julie A Karl, Michael E Graham, Roger W Wiseman, Katelyn E Heimbruch, Samantha M Gieger, Gaby G M Doxiadis, Ronald E Bontrop, David H O'Connor
Very little is currently known about the major histocompatibility complex (MHC) region of cynomolgus macaques (Macaca fascicularis; Mafa) from Chinese breeding centers. We performed comprehensive MHC class I haplotype analysis of 100 cynomolgus macaques from two different centers, with animals from different reported original geographic origins (Vietnamese, Cambodian, and Cambodian/Indonesian mixed-origin). Many of the samples were of known relation to each other (sire, dam, and progeny sets), making it possible to characterize lineage-level haplotypes in these animals...
January 11, 2017: Immunogenetics
https://www.readbyqxmd.com/read/28077894/information-expensiveness-perceived-by-vietnamese-patients-with-respect-to-healthcare-provider-s-choice
#13
Vuong Quan-Hoang
BACKGROUND: Patients have to acquire information to support their decision on choosing a suitable healthcare provider. But in developing countries like Vietnam, accessibility issues remain an obstacle, thus adversely affect both quality and costliness of healthcare information. Vietnamese use both sources from health professionals and friends/relatives, especially when quality of the Internet-based cheaper sources appear to be still questionable. The search of information from both professionals and friends/relatives incurs some cost, which can be viewed as low or high depending low or high accessibility to the sources...
October 2016: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/28077826/-effects-of-a-customized-birth-control-program-for-married-immigrant-postpartum-mothers
#14
So Young Kim, So Young Choi
PURPOSE: This study was conducted to develop a customized birth control program and identify its effects on attitude, subjective norm, behavioral control, intention, and behavior of contraception among immigrant postpartum mothers. METHODS: In this experimental study, Vietnamese, Filipino or Cambodian married immigrant postpartum mothers were recruited. They were assigned to the experiment group (n=21) or control group (n=21). The customized birth control program was provided to the experimental group for 4 weeks...
December 2016: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/28077809/cytotoxic-steroids-from-the-vietnamese-soft-coral-sinularia-conferta
#15
Ninh Thi Ngoc, Pham Thi Mai Huong, Nguyen Van Thanh, Nguyen Thi Phuong Chi, Nguyen Hai Dang, Nguyen Xuan Cuong, Nguyen Hoai Nam, Do Cong Thung, Phan Van Kiem, Chau Van Minh
Twelve steroids, including five new compounds 1-5, were isolated and structurally elucidated from a methanol extract of the Vietnamese soft coral Sinularia conferta. Their cytotoxic effects against three human cancer cell lines, lung carcinoma (A-549), cervical adenocarcinoma (Hela), and pancreatic epithelioid carcinoma (PANC-1), were evaluated using 3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide (MTT) assays. Among isolated compounds, 10 exhibited potent cytotoxic effects on all three tested cell lines with IC50 values of 3...
January 12, 2017: Chemical & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28069063/the-ribosomal-transcription-units-of-haplorchis-pumilio-and-h-taichui-and-the-use-of-28s-rdna-sequences-for-phylogenetic-identification-of-common-heterophyids-in-vietnam
#16
Thanh Hoa Le, Khue Thi Nguyen, Nga Thi Bich Nguyen, Huong Thi Thanh Doan, Do Trung Dung, David Blair
BACKGROUND: Heterophyidiasis is now a major public health threat in many tropical countries. Species in the trematode family Heterophyidae infecting humans include Centrocestus formosanus, Haplorchis pumilio, H. taichui, H. yokogawai, Procerovum varium and Stellantchasmus falcatus. For molecular phylogenetic and systematic studies on trematodes, we need more prospective markers for taxonomic identification and classification. This study provides near-complete ribosomal transcription units (rTU) from Haplorchis pumilio and H...
January 9, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28063345/physical-activity-and-nutrition-program-for-adults-with-metabolic-syndrome-process-evaluation
#17
Van Dinh Tran, Jonine Jancey, Andy Lee, Anthony James, Peter Howat, Le Thi Phuong Mai
INTRODUCTION: The Vietnam Physical Activity and Nutrition (VPAN) program aimed to improve physical activity and nutrition for adults aged 50-65 years with Metabolic Syndrome in Vietnam. The VPAN program consisted of a range of resources and strategies, including an information booklet, resistance band, face-to-face education sessions, and walking groups. This process evaluation assessed the participation, fidelity, satisfaction, and reasons for completing and not-completing the VPAN. METHODS: Data were collected by mixed-methods from a sample of 214 intervention participants...
December 29, 2016: Evaluation and Program Planning
https://www.readbyqxmd.com/read/28058203/do-recommendations-by-healthcare-providers-family-members-friends-and-individual-self-efficacy-increase-uptake-of-hepatitis-b-screening-results-of-a-population-based-study-of-asian-americans
#18
Xiaoxiao Lu, Hee-Soon Juon, Sunmin Lee
BACKGROUND: Hepatitis B virus (HBV) infection disproportionately affects Asian Americans but HBV screening rates among Asian American are substantially low. This study examines the impact of multiple recommendations and self-efficacy on HBV screening uptake among Asian Americans. METHODS: Data for this study were from 872 Chinese, Korean and Vietnamese recruited for a liver cancer prevention program in the Washington D.C - Baltimore metropolitan area. RESULTS: 410 (47%) respondents reported previous HBV screening...
2017: International Journal of MCH and AIDS
https://www.readbyqxmd.com/read/28052109/defining-surrogate-endpoints-for-clinical-trials-in-severe-falciparum-malaria
#19
Atthanee Jeeyapant, Hugh W Kingston, Katherine Plewes, Richard J Maude, Josh Hanson, M Trent Herdman, Stije J Leopold, Thatsanun Ngernseng, Prakaykaew Charunwatthana, Nguyen Hoan Phu, Aniruddha Ghose, M Mahtab Uddin Hasan, Caterina I Fanello, Md Abul Faiz, Tran Tinh Hien, Nicholas P J Day, Nicholas J White, Arjen M Dondorp
BACKGROUND: Clinical trials in severe falciparum malaria require a large sample size to detect clinically meaningful differences in mortality. This means few interventions can be evaluated at any time. Using a validated surrogate endpoint for mortality would provide a useful alternative allowing a smaller sample size. Here we evaluate changes in coma score and plasma lactate as surrogate endpoints for mortality in severe falciparum malaria. METHODS: Three datasets of clinical studies in severe malaria were re-evaluated: studies from Chittagong, Bangladesh (adults), the African 'AQUAMAT' trial comparing artesunate and quinine (children), and the Vietnamese 'AQ' study (adults) comparing artemether with quinine...
2017: PloS One
https://www.readbyqxmd.com/read/28049264/recovery-of-lactobacillus-casei-strain-shirota-lcs-from-the-intestine-of-healthy-vietnamese-adults-after-intake-of-fermented-milk
#20
Truong Tuyet Mai, Duong Van Hop, Trinh Thi Van Anh, Nguyen Thi Lam
To demonstrate the gastrointestinal survival of Lactobacillus casei strain Shirota (LcS) in healthy Vietnamese adults, a fermented milk drink containing LcS was administered daily for 14 days. Twenty-six healthy Vietnamese adults took part in the study. Each participant consumed 65 mL of a fermented milk drink containing LcS daily for 14 days. The drink contained a dose of 10 8 CFU/mL LcS. Fecal samples were collected before, during and after consuming the fermented milk drink. LcS was confirmed by culture and ELISA...
January 2017: Asia Pacific Journal of Clinical Nutrition
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