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https://www.readbyqxmd.com/read/28231519/carotid-systolic-flow-time-with-passive-leg-raise-correlates-with-fluid-status-changes-in-patients-undergoing-dialysis
#1
Pavel Antiperovitch, Eduard Iliescu, Barry Chan
Corrected carotid systolic flow time (CFTc) has been proposed as a measure of volume status in acutely ill patients. This study endeavors to determine whether the change in CFTc with passive leg raise (PLR) maneuver correlates with volume status changes. Dialysis patients at Kingston General Hospital (Kingston, Canada) underwent point-of-care carotid ultrasonography at the beginning and the end of dialysis. With each measurement, 2 values were recorded: the absolute CFTc, and the difference in CFTc before and after the PLR maneuver...
February 10, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28230403/development-of-essentialist-thinking-about-religion-categories-in-northern-ireland-and-the-united-states
#2
Kirsty Smyth, Aidan Feeney, R Cole Eidson, John D Coley
Social essentialism, the belief that members of certain social categories share unobservable properties, licenses expectations that those categories are natural and a good basis for inference. A challenge for cognitive developmental theory is to give an account of how children come to develop essentialist beliefs about socially important categories. Previous evidence from Israel suggests that kindergarteners selectively engage in essentialist reasoning about culturally salient (ethnicity) categories, and that this is attenuated among children in integrated schools...
March 2017: Developmental Psychology
https://www.readbyqxmd.com/read/28229567/repeated-sprint-training-in-the-fasted-state-during-ramadan-morning-or-evening-training
#3
Asma Aloui, Tarak Driss, Hana Baklouti, Hamdi Jaafar, Omar Hammouda, Karim Chamari, Nizar Souissi
BACKGROUND: The present study assessed the optimal moment-of-day for repeated-sprint training in the fasted state during Ramadan. METHODS: Thirty amateur soccer players were randomly assigned to a morning training group (MTG, training at ~08:00 a.m., n = 10), an evening training group (ETG, training at ~06:00 p.m., n = 10), and a control group (n = 10). Training sessions, conducted on alternate days, consisted of 3 sets of 6 × 40-m shuttle sprints (2 × 20 m with 180° direction changes)...
February 22, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28229483/venous-hemodialysis-catheters-and-cardiac-implantable-electronic-devices-avoiding-a-high-risk-combination
#4
EDITORIAL
Theodore F Saad, Henry L Weiner
End-stage renal disease is frequently accompanied by cardiac comorbidity that warrants treatment with a cardiovascular implantable electronic device (permanent pacemaker or implantable cardioverter-defibrillator). In the United States, chronic hemodialysis (HD) population, cardiac implantable devices are present in up to 10.5% of patients; a venous HD catheter is utilized for blood access in 18% of prevalent patients. The concomitant presence of a venous HD catheter and cardiovascular implantable device creates a high-risk circumstance, with potential for causing symptomatic central venous stenosis, and for developing complicated endovascular infection...
February 23, 2017: Seminars in Dialysis
https://www.readbyqxmd.com/read/28229032/role-of-dual-energy-computed-tomography-imaging-in-the-diagnosis-of-gout
#5
REVIEW
Divya Jayakumar, Shiv T Sehra, Suneesh Anand, Gary W Stallings, Abhijeet Danve
Gout is a well-known inflammatory arthritis and affects four percent of the United States population. It results from the deposition of uric acid crystals in joints, tendons, bursae, and other surrounding tissues. Prevalence of gout has increased in the recent decade. Gout is usually seen in conjunction with other chronic comorbid conditions like cardiac disease, metabolic syndrome, and renal disease. The diagnosis of this inflammatory arthritis is confirmed by visualization of monosodium urate (MSU) crystals in the synovial fluid...
January 20, 2017: Curēus
https://www.readbyqxmd.com/read/28228583/food-responsiveness-regulates-episodic-behavioral-states-in-caenorhabditis-elegans
#6
Richard J McCloskey, Anthony D Fouad, Matthew A Churgin, Christopher Fang-Yen
Animals optimize survival and reproduction in part through control of behavioral states, which depend on the organism's internal and external environments. In the nematode C. elegans, a variety of behavioral states have been described, including roaming, dwelling, quiescence, and episodic swimming. These states have been considered in isolation, under varied experimental conditions, making it difficult to establish a unified picture of how they are regulated. Using long-term imaging, we examined C. elegans episodic behavioral states under varied mechanical and nutritional environments...
February 22, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28228526/trimethylamine-n-oxide-stabilizes-proteins-via-a-distinct-mechanism-compared-with-betaine-and-glycine
#7
Yi-Ting Liao, Anthony C Manson, Michael R DeLyser, William G Noid, Paul S Cremer
We report experimental and computational studies investigating the effects of three osmolytes, trimethylamine N-oxide (TMAO), betaine, and glycine, on the hydrophobic collapse of an elastin-like polypeptide (ELP). All three osmolytes stabilize collapsed conformations of the ELP and reduce the lower critical solution temperature (LSCT) linearly with osmolyte concentration. As expected from conventional preferential solvation arguments, betaine and glycine both increase the surface tension at the air-water interface...
February 22, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28228511/the-opiliones-tree-of-life-shedding-light-on-harvestmen-relationships-through-transcriptomics
#8
Rosa Fernández, Prashant P Sharma, Ana Lúcia Tourinho, Gonzalo Giribet
Opiliones are iconic arachnids with a Palaeozoic origin and a diversity that reflects ancient biogeographic patterns dating back at least to the times of Pangea. Owing to interest in harvestman diversity, evolution and biogeography, their relationships have been thoroughly studied using morphology and PCR-based Sanger approaches to infer their systematic relationships. More recently, two studies utilized transcriptomics-based phylogenomics to explore their basal relationships and diversification, but sampling was limiting for understanding deep evolutionary patterns, as they lacked good taxon representation at the family level...
February 22, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28228489/age-dependent-shift-in-macrophage-polarisation-causes-inflammation-mediated-degeneration-of-enteric-nervous-system
#9
Laren Becker, Linh Nguyen, Jaspreet Gill, Subhash Kulkarni, Pankaj Jay Pasricha, Aida Habtezion
OBJECTIVE: The enteric nervous system (ENS) undergoes neuronal loss and degenerative changes with age. The cause of this neurodegeneration is poorly understood. Muscularis macrophages residing in close proximity to enteric ganglia maintain neuromuscular function via direct crosstalk with enteric neurons and have been implicated in the pathogenesis of GI motility disorders like gastroparesis and postoperative ileus. The aim of this study was to assess whether ageing causes alterations in macrophage phenotype that contributes to age-related degeneration of the ENS...
February 21, 2017: Gut
https://www.readbyqxmd.com/read/28228233/analyzing-complex-mixtures-of-drug-like-molecules-ion-mobility-as-an-adjunct-to-existing-liquid-chromatography-tandem-mass-spectrometry-methods
#10
Jasper Boschmans, Filip Lemière, Frank Sobott
The use of traveling wave ion mobility mass spectrometry (TWIMS) is evaluated in conjunction with, and as a possible alternative to, conventional LC-MS(/MS) methods for the separation and characterization of drug-like compounds and metabolites. As a model system we use an in vitro incubation mixture of the chemotherapeutic agent melphalan, which results in more than ten closely related hydrolysis products and chain-like oligomers. Ion mobility as a filtering tool results in the separation of ions of interest from interfering ions, based on charge state and shape/size...
February 14, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28228094/sfreemap-a-simulation-free-tool-for-stochastic-mapping
#11
Diego Pasqualin, Marcos Barbeitos, Fabiano Silva
BACKGROUND: Stochastic mapping is frequently used in comparative biology to simulate character evolution, enabling the probabilistic computation of statistics such as number of state transitions along a tree and distribution of states in its internal nodes. Common implementations rely on Continuous-time Markov Chain simulations whose parameters are difficult to adjust and subjected to inherent inaccuracy. Thus, researchers must run a large number of simulations in order to obtain adequate estimates...
February 22, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28227942/unified-phase-variables-of-relative-degree-two-for-human-locomotion
#12
Dario J Villarreal, Robert D Gregg, Dario J Villarreal, Robert D Gregg, Robert D Gregg, Dario J Villarreal
A starting point to achieve stable locomotion is synchronizing the leg joint kinematics during the gait cycle. Some biped robots parameterize a nonlinear controller (e.g., input-output feedback linearization) whose main objective is to track specific kinematic trajectories as a function of a single mechanical variable (i.e., a phase variable) in order to allow the robot to walk. A phase variable capable of parameterizing the entire gait cycle, the hip phase angle, has been used to control wearable robots and was recently shown to provide a robust representation of the phase of human gait...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227803/ear-eeg-allows-extraction-of-neural-responses-in-challenging-listening-scenarios-a-future-technology-for-hearing-aids
#13
L Fiedler, J Obleser, T Lunner, C Graversen, L Fiedler, J Obleser, T Lunner, C Graversen, J Obleser, C Graversen, L Fiedler, T Lunner
Advances in brain-computer interface research have recently empowered the development of wearable sensors to record mobile electroencephalography (EEG) as an unobtrusive and easy-to-use alternative to conventional scalp EEG. One such mobile solution is to record EEG from the ear canal, which has been validated for auditory steady state responses and discrete event related potentials (ERPs). However, it is still under discussion where to place recording and reference electrodes to capture best responses to auditory stimuli...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227621/non-contact-automatic-respiration-monitoring-in-restrained-rodents
#14
Behnaz Rezaei, Jared Lowe, Jason R Yee, Stephen Porges, Sarah Ostadabbas, Behnaz Rezaei, Jared Lowe, Jason R Yee, Stephen Porges, Sarah Ostadabbas, Sarah Ostadabbas, Jason R Yee, Stephen Porges, Jared Lowe, Behnaz Rezaei
Prairie voles are socially monogamous rodents that form social bonds similar to those seen in primates. Social behavior investigation in these species, that include studying their breathing regulation, can provide us with an invaluable psychological model to understand social and emotional functions in both animals and humans. There have been several studies associated with the respiratory pattern of these species in the state of fear-induced defense. However, non-invasive measurement methods employed so far suffer from the lack of a natural experiment environment for the rodents...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227407/recursive-feature-elimination-for-biomarker-discovery-in-resting-state-functional-connectivity
#15
Hariharan Ravishankar, Radhika Madhavan, Rakesh Mullick, Teena Shetty, Luca Marinelli, Suresh E Joel, Hariharan Ravishankar, Radhika Madhavan, Rakesh Mullick, Teena Shetty, Luca Marinelli, Suresh E Joel, Suresh E Joel, Teena Shetty, Luca Marinelli, Rakesh Mullick, Hariharan Ravishankar, Radhika Madhavan
Biomarker discovery involves finding correlations between features and clinical symptoms to aid clinical decision. This task is especially difficult in resting state functional magnetic resonance imaging (rs-fMRI) data due to low SNR, high-dimensionality of images, inter-subject and intra-subject variability and small numbers of subjects compared to the number of derived features. Traditional univariate analysis suffers from the problem of multiple comparisons. Here, we adopt an alternative data-driven method for identifying population differences in functional connectivity...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227365/integrated-quantification-based-on-confocal-imaging-cell-crowding-modulates-heterogeneity-in-gpcr-mediated-calcium-oscillation
#16
Jophin G Joseph, S Nanda, S Vennamalla, G Bhure, Ranjana Singh, Soumya Jana, Lopamudra Giri, Jophin G Joseph, S Nanda, S Vennamalla, G Bhure, Ranjana Singh, Soumya Jana, Lopamudra Giri, Soumya Jana, Lopamudra Giri, Jophin G Joseph, S Nanda, Ranjana Singh, G Bhure, S Vennamalla
Results from single cell imaging, facilitated by high resolution microscopy, have demonstrated cell-to-cell variability within the same cell population in contexts ranging from cell growth to cell migration. Recent studies suggest that such variability conveys important information about diseased states. However, manual analysis and interpretation of heterogeneous calcium oscillation based on time-lapsed images, as practiced today, is tedious, and essentially infeasible for large datasets. As a practical alternative, we present an integrated platform that includes calcium imaging using confocal microscope, algorithmic cell segmentation, and statistical analysis...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227273/body-position-classification-for-cardiorespiratory-measurement
#17
Marcel Mlynczak, Martin Berka, Wiktor Niewiadomski, Gerard Cybulski, Marcel Mlynczak, Martin Berka, Wiktor Niewiadomski, Gerard Cybulski, Marcel Mlynczak, Martin Berka, Gerard Cybulski, Wiktor Niewiadomski
Heart activity, or at least heart rate variability, is associated with body position. Our previous studies have confirmed that impedance pneumography may be used to record respiratory function, but the calibration coefficients for this method depend on position. Data were collected from 24 students (12 male, 12 female), who alternated positions between lying (on front, back, and right side), sitting and standing. Signals from an attached iPhone's internal sensors (accelerometer, gyroscope, magnetometer) were recorded and attitude relative to gravity was calculated...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227112/estimation-of-macro-sleep-stages-from-whole-night-audio-analysis
#18
E Dafna, M Halevi, D Ben Or, A Tarasiuk, Y Zigel, E Dafna, M Halevi, D Ben Or, A Tarasiuk, Y Zigel, D Ben Or, Y Zigel, M Halevi, E Dafna, A Tarasiuk
During routine sleep diagnostic procedure, sleep is broadly divided into three states: rapid eye movement (REM), non-REM (NREM) states, and wake, frequently named macro-sleep stages (MSS). In this study, we present a pioneering attempt for MSS detection using full night audio analysis. Our working hypothesis is that there might be differences in sound properties within each MSS due to breathing efforts (or snores) and body movements in bed. In this study, audio signals of 35 patients referred to a sleep laboratory were recorded and analyzed...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227095/a-small-portable-battery-powered-brain-computer-interface-system-for-motor-rehabilitation
#19
Colin M McCrimmon, Ming Wang, Lucas Silva Lopes, Po T Wang, Alireza Karimi-Bidhendi, Charles Y Liu, Payam Heydari, Zoran Nenadic, An H Do, Colin M McCrimmon, Ming Wang, Lucas Silva Lopes, Po T Wang, Alireza Karimi-Bidhendi, Charles Y Liu, Payam Heydari, Zoran Nenadic, An H Do, Ming Wang, An H Do, Zoran Nenadic, Colin M McCrimmon, Alireza Karimi-Bidhendi, Lucas Silva Lopes, Po T Wang, Charles Y Liu, Payam Heydari
Motor rehabilitation using brain-computer interface (BCI) systems may facilitate functional recovery in individuals after stroke or spinal cord injury. Nevertheless, these systems are typically ill-suited for widespread adoption due to their size, cost, and complexity. In this paper, a small, portable, and extremely cost-efficient (<;$200) BCI system has been developed using a custom electroencephalographic (EEG) amplifier array, and a commercial microcontroller and touchscreen. The system's performance was tested using a movement-related BCI task in 3 able-bodied subjects with minimal previous BCI experience...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226799/an-audiovisual-bci-system-for-assisting-clinical-communication-assessment-in-patients-with-disorders-of-consciousness-a-case-study
#20
Fei Wang, Yanbin He, Jun Qu, Qiuyou Xie, Qing Lin, Xiaoxiao Ni, Yan Chen, Ronghao Yu, Chin-Teng Lin, Yuanqing Li, Fei Wang, Yanbin He, Jun Qu, Qiuyou Xie, Qing Lin, Xiaoxiao Ni, Yan Chen, Ronghao Yu, Chin-Teng Lin, Yuanqing Li, Chin-Teng Lin, Fei Wang, Ronghao Yu, Jun Qu, Yan Chen, Yanbin He, Qiuyou Xie, Yuanqing Li, Xiaoxiao Ni, Qing Lin
The JFK Coma Recovery Scale-Revised (JFK CRS-R), a behavioral scale, is often used for clinical assessments of patients with disorders of consciousness (DOC), such as patients in a vegetative state. However, there has been a high rate of clinical misdiagnosis with the JFK CRS-R because patients with severe brain injures cannot provide sufficient behavioral responses. It is particularly difficult to evaluate the communication function in DOC patients using the JFK CRS-R because a higher level of behavioral responses is needed for communication assessments than for many other assessments, such as an auditory startle assessment...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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