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Chronic psychosocial stress

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https://www.readbyqxmd.com/read/28333778/cochlear-implant-in-severe-impaired-psychiatric-patients-a-case-series
#1
Ioana T Herisanu, Mark Praetorius, Margarete Mattern
OBJECTIVE: Psychotic disorders and intelligence deficiencies are no longer contraindications for cochlear implantation regarding the revised German guidelines from May 2012. This article aims to evaluate the outcome of patients with severe psychiatric comorbidities. Therefore the database of the Cochlear Implant Center of the University Hospital of Heidelberg was investigated. STUDY DESIGN: Retrospective case review. METHODS: We present three patients who received a cochlear implant (CI) despite a serious psychiatric disorder...
March 22, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28315459/dynamic-reorganization-of-intrinsic-functional-networks-in-the-mouse-brain
#2
Joanes Grandjean, Maria Giulia Preti, Thomas Aw Bolton, Michaela Buerge, Erich Seifritz, Christopher R Pryce, Dimitri Van De Ville, Markus Rudin
Functional connectivity (FC) derived from resting-state functional magnetic resonance imaging (rs-fMRI) allows for the integrative study of neuronal processes at a macroscopic level. The majority of studies to date have assumed stationary interactions between brain regions, without considering the dynamic aspects of network organization. Only recently has the latter received increased attention, predominantly in human studies. Applying dynamic FC (dFC) analysis to mice is attractive given the relative simplicity of the mouse brain and the possibility to explore mechanisms underlying network dynamics using pharmacological, environmental or genetic interventions...
March 14, 2017: NeuroImage
https://www.readbyqxmd.com/read/28314964/increased-intake-of-energy-dense-diet-and-negative-energy-balance-in-a-mouse-model-of-chronic-psychosocial-defeat
#3
Roberto Coccurello, Adele Romano, Giacomo Giacovazzo, Bianca Tempesta, Marco Fiore, Anna Maria Giudetti, Ilaria Marrocco, Fabio Altieri, Anna Moles, Silvana Gaetani
PURPOSE: Chronic exposure to stress may represent a risk factor for developing metabolic and eating disorders, mostly driven by the overconsumption of easily accessible energy-dense palatable food, although the mechanisms involved remain still unclear. In this study, we used an ethologically oriented murine model of chronic stress caused by chronic psychosocial defeat (CPD) to investigate the effects of unrestricted access to a palatable high fat diet (HFD) on food intake, body weight, energy homeostasis, and expression of different brain neuropeptides...
March 17, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28306624/the-association-of-work-characteristics-with-ovarian-cancer-risk-and-mortality
#4
Claudia Trudel-Fitzgerald, Elizabeth M Poole, Annika Idahl, Eva Lundin, Anil K Sood, Ichiro Kawachi, Laura D Kubzansky, Shelley S Tworoger
OBJECTIVE: Ovarian cancer (OvCA) is a leading cause of cancer death for women. Depression and social isolation have been associated with a higher OvCA risk and poorer survival, but other forms of chronic psychosocial stress, including work-related characteristics, remain understudied. METHODS: Women from three prospective cohorts (Nurses' Health Study (NHS), n=31,754; Nurses' Health Study II (NHSII), n=74,260; Northern Sweden Health and Disease Study (NSHDS); nnested case-control study=196) completed a job questionnaire, assessing demand and control at work, social support provided by coworkers and supervisor, and job security...
March 17, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28299791/prospective-pilot-study-of-the-mastering-each-new-direction-psychosocial-family-systems-program-for-pediatric-chronic-illness
#5
Brian Distelberg, Daniel Tapanes, Natacha D Emerson, Whitney N Brown, Deepti Vaswani, Jackie Williams-Reade, Ara M Anspikian, Susanne Montgomery
Psychosocial interventions for pediatric chronic illness (CI) have been shown to support health management. Interventions that include a family systems approach offer potentially stronger and more sustainable improvements. This study explores the biopsychosocial benefits of a novel family systems psychosocial intervention (MEND: Mastering Each New Direction). Forty-five families participated in a 21-session intensive outpatient family systems-based program for pediatric CI. Within this single arm design, families were measured on five domains of Health-Related Quality of Life (HRQL) self-report measures; Stress, Cognitive Functioning, Mental Health, Child HRQL, Family Functioning...
March 15, 2017: Family Process
https://www.readbyqxmd.com/read/28291302/psychosocial-group-interventions-to-improve-psychological-well-being-in-adults-living-with-hiv
#6
REVIEW
Ingrid van der Heijden, Naeemah Abrahams, David Sinclair
BACKGROUND: Being diagnosed with human immunodeficiency virus (HIV), and labelled with a chronic, life-threatening, and often stigmatizing disease, can impact on a person's well-being. Psychosocial group interventions aim to improve life-functioning and coping as individuals adjust to the diagnosis. OBJECTIVES: To examine the effectiveness of psychosocial group interventions for improving the psychological well-being of adults living with HIV/AIDS. SEARCH METHODS: We searched the following electronic databases up to 14 March 2016: the Cochrane Central Register of Controlled Trials (CENTRAL) published in the Cochrane Library (Issue 2, 2016), PubMed (MEDLINE) (1996 to 14 March 2016), Embase (1996 to 14 March 2016), and Clinical Trials...
March 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28289275/epigenetic-programming-by-stress-and-glucocorticoids-along-the-human-lifespan
#7
A S Zannas, G P Chrousos
Psychosocial stress triggers a set of behavioral, neural, hormonal, and molecular responses that can be a driving force for survival when adaptive and time-limited, but may also contribute to a host of disease states if dysregulated or chronic. The beneficial or detrimental effects of stress are largely mediated by the hypothalamic-pituitary axis, a highly conserved neurohormonal cascade that culminates in systemic secretion of glucocorticoids. Glucocorticoids activate the glucocorticoid receptor, a ubiquitous nuclear receptor that not only causes widespread changes in transcriptional programs, but also induces lasting epigenetic modifications in many target tissues...
March 14, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28283812/behavioral-treatments-for-post-traumatic-headache
#8
REVIEW
Felicia Fraser, Yuka Matsuzawa, Yuen Shan Christine Lee, Mia Minen
PURPOSE OF REVIEW: Post-traumatic headache (PTH) is a common headache type after traumatic brain injury (TBI). There are no FDA approved medications for PTH, and it is unknown how medications can affect the brain's ability to recover from TBI. Thus, we sought to examine the biopsychosocial factors that influence PTH and the non-pharmacologic treatments studied for headache treatment. We also sought to determine if there is literature examining whether the non-pharmacologic treatments influence the biopsychosocial factors...
May 2017: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/28277702/pathway-from-ptsd-to-respiratory-health-longitudinal-evidence-from-a-psychosocial-intervention
#9
Monika A Waszczuk, Xiaotong Li, Evelyn J Bromet, Adam Gonzalez, Michael J Zvolensky, Camilo Ruggero, Benjamin J Luft, Roman Kotov
OBJECTIVE: Respiratory illness and posttraumatic stress disorder (PTSD) are common debilitating conditions that frequently co-occur. Observational studies indicate that PTSD, independently of smoking, is a major risk and maintenance factor for lower respiratory symptoms (LRS). The current study experimentally tested this etiologic pathway by investigating whether LRS can be reduced by treating PTSD symptoms. METHOD: Ninety daily smokers exposed to the World Trade Center (WTC) disaster (mean age 50 years, 28% female; 68% White) completed 8-session group-based weekly comprehensive trauma management and smoking cessation treatment that focused on skills to alleviate PTSD symptoms...
March 9, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/28263537/chronic-unpredictable-mild-stress-paradigm-in-male-wistar-rats-effect-on-anxiety-and-depressive-like-behavior
#10
Romana Koprdova, Eszter Bögi, Kristína Belovičová, Natália Sedláčková, Monika Okuliarová, Eduard Ujházy, Mojmír Mach
OBJECTIVES: There are several models of depression. Chronic unpredictable mild stress (CMS) appears to have the greatest validity, although it is often being criticized for low reliability. METHODS: Male Wistar/DV rats were used in this study to assess our modified 2-week model of CMS as a combination of psychosocial, physical and metabolic stressors and to compare the effect of acute administration of venlafaxine (VFX) and diazepam (DZP), either in stress or no stress conditions...
December 18, 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28242013/targeting-the-microbiota-gut-brain-axis-prebiotics-have-anxiolytic-and-antidepressant-like-effects-and-reverse-the-impact-of-chronic-stress-in-mice
#11
Aurelijus Burokas, Silvia Arboleya, Rachel D Moloney, Veronica L Peterson, Kiera Murphy, Gerard Clarke, Catherine Stanton, Timothy G Dinan, John F Cryan
BACKGROUND: The realization that the microbiota-gut-brain axis plays a critical role in health and disease, including neuropsychiatric disorders, is rapidly advancing. Nurturing a beneficial gut microbiome with prebiotics, such as fructo-oligosaccharides (FOS) and galacto-oligosaccharides (GOS), is an appealing but underinvestigated microbiota manipulation. Here we tested whether chronic prebiotic treatment modifies behavior across domains relevant to anxiety, depression, cognition, stress response, and social behavior...
February 24, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/28229112/chronic-psychosocial-stressors-in-adulthood-studies-in-mice-rats-and-tree-shrews
#12
REVIEW
Christopher R Pryce, Eberhard Fuchs
Human psychological stress is the major environmental risk factor for major depression and certain of the anxiety disorders. Psychological stressors often occur in the context of the adult social environment, and they or the memory formed of them impact on the individual across an extended period, thereby constituting chronic psychosocial stress (CPS). Psychosocial stressors often involve loss to the individual, such as the ending of a social relationship or the onset of interpersonal conflict leading to loss of social control and predictability...
February 2017: Neurobiology of Stress
https://www.readbyqxmd.com/read/28219813/an-adverse-early-life-environment-can-enhance-stress-resilience-in-adulthood
#13
Sara Santarelli, Christoph Zimmermann, Georgia Kalideris, Sylvie L Lesuis, Janine Arloth, Andrés Uribe, Carine Dournes, Georgia Balsevich, Jakob Hartmann, Mercè Masana, Elisabeth B Binder, Dietmar Spengler, Mathias V Schmidt
Chronic stress is a major risk factor for depression. Interestingly, not all individuals develop psychopathology after chronic stress exposure. In contrast to the prevailing view that stress effects are cumulative and increase stress vulnerability throughout life, the match/mismatch hypothesis of psychiatric disorders. The match/mismatch hypothesis proposes that individuals who experience moderate levels of early life psychosocial stress can acquire resilience to renewed stress exposure later in life. Here, we have tested this hypothesis by comparing the developmental effects of 2 opposite early life conditions, when followed by 2 opposite adult environments...
February 7, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28216719/diagnosis-and-management-of-chronic-pruritus-an-expert-consensus-review
#14
REVIEW
Murlidhar Rajagopalan, Abir Saraswat, Kiran Godse, D S Krupa Shankar, Sanjiv Kandhari, Shrutakirthi D Shenoi, Sushil Tahiliani, V Vijay Zawar
The aim of this study is to formulate the best clinical practice in the diagnosis and management of chronic pruritus (CP). We searched PubMed, EMBASE, Scopus, Web of Science, and the WHO's regional databases, for studies on "Diagnosis and management of chronic pruritus" from January 1, 2014, to July 31, 2015. We included programmatic reports and hand-searched references of published reviews and articles. Two independent reviewers screened articles and extracted data. We screened 87 of 95 studies that contained qualitative data...
January 2017: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/28185874/psychosocial-stress-on-neuroinflammation-and-cognitive-dysfunctions-in-alzheimer-s-disease-the-emerging-role-for-microglia
#15
REVIEW
Sami Piirainen, Andrew Youssef, Cai Song, Allan V Kalueff, Gary E Landreth, Tarja Malm, Li Tian
Chronic psychosocial stress is increasingly recognized as a risk factor for late-onset Alzheimer's disease (LOAD) and associated cognitive deficits. Chronic stress also primes microglia and induces inflammatory responses in the adult brain, thereby compromising synapse-supportive roles of microglia and deteriorating cognitive functions during aging. Substantial evidence demonstrates that failure of microglia to clear abnormally accumulating amyloid-beta (Aβ) peptide contributes to neuroinflammation and neurodegeneration in AD...
February 6, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28175998/-neglect-like-symptoms-after-operations-on-the-upper-extremities
#16
K Welsch, P Bialas, V Köllner, T Volk
BACKGROUND: Neglect-like symptoms (NLS) describe the experience of perceiving a limb as foreign and could be detected in chronic pain disorders as well as after knee joint replacement. The aim of the present study was to find out whether patients with and without NLS after surgery of the upper extremities differ with respect to pain intensity and psychosocial variables and if NLS are associated with chronic postoperative pain (CPSP). METHODS: In this study 241 patients were interviewed using a validated questionnaire preoperatively as well as 1 day, 4 weeks, 3 months and 6 months postoperatively...
February 7, 2017: Der Schmerz
https://www.readbyqxmd.com/read/28170426/chronic-social-stress-in-pigs-impairs-intestinal-barrier-and-nutrient-transporter-function-and-alters-neuro-immune-mediator-and-receptor-expression
#17
Yihang Li, Zehe Song, Katelyn A Kerr, Adam J Moeser
Psychosocial stress is a major factor driving gastrointestinal (GI) pathophysiology and disease susceptibility in humans and animals. The mechanisms governing susceptibility to stress-induced GI disease remain poorly understood. In the present study, we investigated the influence of chronic social stress (CSS) in pigs, induced by 7 d of chronic mixing/crowding stress, on intestinal barrier and nutrient transport function, corticotropin releasing factor (CRF) signaling and immunological responses. Results from this study showed that CSS resulted in a significant impairment of ileal and colonic barrier function indicated by reduced transepithelial electrical resistance (TER) in the ileum and increased FD4 flux in the ileum (by 0...
2017: PloS One
https://www.readbyqxmd.com/read/28157442/a-nationally-scaled-telebehavioral-health-program-for-chronic-pain-characteristics-goals-and-psychological-outcomes
#18
Heidi Mochari-Greenberger, Aimee Peters, Lee Vue, Reena L Pande
BACKGROUND: Millions of U.S. adults suffer from chronic pain with a high prevalence of comorbid mental health issues. Telehealth-delivered behavioral therapy for chronic pain has been evaluated in the research setting. The purpose of this study was 1) to describe a nationally scaled, standardized, telebehavioral therapy program for patients with chronic pain and behavioral comorbidities, and 2) evaluate characteristics, goals, and psychosocial outcomes among program participants. MATERIALS AND METHODS: This was mixed-methods retrospective cohort analysis among consecutive program graduates (mean age 53y; 24% male)...
February 3, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/28139727/cortisol-awakening-response-and-acute-stress-reactivity-in-first-nations-people
#19
Maximus Berger, Anthony Leicht, Angela Slatcher, Ann Katrin Kraeuter, Sarangan Ketheesan, Sarah Larkins, Zoltán Sarnyai
First Nations people globally have a higher incidence of mental disorders and non-communicable diseases. These health inequalities are partially attributed to a complex network of social and environmental factors which likely converge on chronic psychosocial stress. We hypothesized that alterations in stress processing and the regulation of the hypothalamic-pituitary-adrenal axis might underlie health disparities in First Nations people. We assessed the cortisol awakening response and the dynamic response to a laboratory induced psychosocial stress of young Indigenous tertiary students (n = 11, mean age 23...
January 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28135659/new-insights-into-the-pathogenesis-and-treatment-of-irritable-bowel-syndrome
#20
REVIEW
Joanna Oświęcimska, Agnieszka Szymlak, Wojciech Roczniak, Katarzyna Girczys-Połedniok, Jarosław Kwiecień
Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders (FGID), characterized by abdominal pain and a change in stool form that cannot be explained by structural abnormalities. Its prevalence ranges from 9 to 23% of the worldwide population. The pathophysiology of IBS is diverse and not well understood. Biopsychosocial concept assumes that the disease is a product of psychosocial factors and altered at multiple levels of gut physiology interactions. Some aetiological factors have been identified, yet...
January 27, 2017: Advances in Medical Sciences
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