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Chronic psychological stress

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https://www.readbyqxmd.com/read/28331360/clear-differences-in-cerebrospinal-fluid-proteome-between-women-with-chronic-widespread-pain-and-healthy-women-a-multivariate-explorative-cross-sectional-study
#1
Patrik Olausson, Bijar Ghafouri, Emmanuel Bäckryd, Björn Gerdle
INTRODUCTION: Frequent chronic local pain can develop into chronic widespread pain (CWP). The spread of pain is correlated with pain intensity, anxiety, and depression, conditions that ultimately lead to a poor quality of life. Knowledge is incomplete about CWP's etiology, although it has been suggested that both central hyperexcitability and/or a combination with peripheral factors may be involved. Cerebrospinal fluid (CSF) could act as a mirror for the central nervous system as proteins are signal substances that activate the formation of algesics and control nociceptive processes...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28330395/changes-of-posttraumatic-stress-responses-in-evacuated-residents-and-their-related-factors
#2
Misari Oe, Hideto Takahashi, Masaharu Maeda, Mayumi Harigane, Senta Fujii, Itaru Miura, Masato Nagai, Hirooki Yabe, Tetsuya Ohira, Yuriko Suzuki, Seiji Yasumura, Masafumi Abe
The longitudinal posttraumatic stress responses and resilient factors after the Fukushima Daiichi Nuclear Power Plant are yet unknown. Here we attempted to quantify the patterns of the course of posttraumatic stress disorder (PTSD) symptoms and we explored the factors associated with psychological recovery. The subjects were 12 371 residents in the municipalities categorized as the forced evacuated area. We categorized the subjects' PTSD symptoms into 4 groups: Chronic, Resistant, Recovered, and Non-recovered...
March 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28320277/mechanisms-of-brain-glucocorticoid-resistance-in-stress-induced-psychopathologies
#3
REVIEW
V M Merkulov, T I Merkulova, N P Bondar
Exposure to stress activates the hypothalamic-pituitary-adrenal axis and leads to increased levels of glucocorticoid (GC) hormones. Prolonged elevation of GC levels causes neuronal dysfunction, decreases the density of synapses, and impairs neuronal plasticity. Decreased sensitivity to glucocorticoids (glucocorticoid resistance) that develops as a result of chronic stress is one of the characteristic features of stress-induced psychopathologies. In this article, we reviewed the published data on proposed molecular mechanisms that contribute to the development of glucocorticoid resistance in brain, including changes in the expression of the glucocorticoid receptor (GR) gene, biosynthesis of GR isoforms, and GR posttranslational modifications...
March 2017: Biochemistry. Biokhimii︠a︡
https://www.readbyqxmd.com/read/28314616/corrigendum-to-is-there-a-relationship-between-psychological-stress-or-anxiety-and-chronic-nonspecific-neck-arm-pain-in-adults-a-systematic-review-and-meta-analysis-j-psychossom-res-90-2016-70-81
#4
Gorka Ortego, Jorge Hugo Villafañe, Victor Doménech-García, Pedro Berjano, Lucia Bertozzi, Pablo Herrero
No abstract text is available yet for this article.
March 14, 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28300333/psychological-stress-induced-colonic-barrier-dysfunction-role-of-immune-mediated-mechanisms
#5
P Hattay, D K Prusator, L Tran, B Greenwood-Van Meerveld
BACKGROUND: Evidence suggests that patients with irritable bowel syndrome (IBS) exhibit increases in gut permeability and alterations in tight junction (TJ) protein expression. Although psychological stress worsens IBS symptoms, the mechanisms by which stress enhances gut permeability and affects TJ protein expression remain to be determined. Here, we test the hypothesis that chronic intermittent psychological stress activates the release of proinflammatory cytokines to alter TJ proteins and promotes increased gut permeability...
March 16, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28298818/evaluation-of-association-between-psychological-stress-and-serum-cortisol-levels-in-patients-with-chronic-periodontitis-estimation-of-relationship-between-psychological-stress-and-periodontal-status
#6
Roshni Jaiswal, Nina Shenoy, Biju Thomas
BACKGROUND: Stress classically describes a destructive notion that can have a bearing on one's physical and mental health. It may also add to an increased propensity to periodontal disease. AIM: To investigate the association between psychological stress and serum cortisol levels in patients with chronic periodontitis. MATERIALS AND METHODS: Forty subjects were recruited from the outpatient department at the Department of Periodontics, from a college in Mangalore, divided into two groups, i...
July 2016: Journal of Indian Society of Periodontology
https://www.readbyqxmd.com/read/28295837/compromised-hippocampus-striatum-pathway-as-a-potential-imaging-biomarker-of-mild-traumatic-brain-injury-and-posttraumatic-stress-disorder
#7
D Rangaprakash, Gopikrishna Deshpande, Thomas A Daniel, Adam M Goodman, Jennifer L Robinson, Nouha Salibi, Jeffrey S Katz, Thomas S Denney, Michael N Dretsch
OBJECTIVES: Military service members risk acquiring posttraumatic stress disorder (PTSD) and mild-traumatic brain injury (mTBI), with high comorbidity. Owing to overlapping symptomatology in chronic mTBI or postconcussion syndrome (PCS) and PTSD, it is difficult to assess the etiology of a patient's condition without objective measures. Using resting-state functional MRI in a novel framework, we tested the hypothesis that their neural signatures are characterized by functionally hyperconnected brain regions which are less variable over time...
March 15, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28292741/writing-for-health-rationale-and-protocol-for-a-randomized-controlled-trial-of-internet-based-benefit-finding-writing-for-adults-with-type-1-or-type-2-diabetes
#8
Joanna Crawford, Kay Wilhelm, Lisa Robins, Judy Proudfoot
BACKGROUND: Diabetes mellitus is Australia's fastest growing chronic disease, and has high comorbidity with depression. Both subthreshold depression and diabetes distress are common amongst people with type 1 or type 2 diabetes, and are associated with poorer diabetes self-care. A need exists for low-intensity self-help interventions for large numbers of people with diabetes and diabetes distress or subthreshold depression, as part of a stepped-care approach to meeting the psychological needs of people with diabetes...
March 14, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28291302/psychosocial-group-interventions-to-improve-psychological-well-being-in-adults-living-with-hiv
#9
REVIEW
Ingrid van der Heijden, Naeemah Abrahams, David Sinclair
BACKGROUND: Being diagnosed with human immunodeficiency virus (HIV), and labelled with a chronic, life-threatening, and often stigmatizing disease, can impact on a person's well-being. Psychosocial group interventions aim to improve life-functioning and coping as individuals adjust to the diagnosis. OBJECTIVES: To examine the effectiveness of psychosocial group interventions for improving the psychological well-being of adults living with HIV/AIDS. SEARCH METHODS: We searched the following electronic databases up to 14 March 2016: the Cochrane Central Register of Controlled Trials (CENTRAL) published in the Cochrane Library (Issue 2, 2016), PubMed (MEDLINE) (1996 to 14 March 2016), Embase (1996 to 14 March 2016), and Clinical Trials...
March 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28289513/role-of-%C3%AE-amino-3-hydroxy-5-methyl-4-isoxazole-propionic-acid-receptor-regulation-in-stress-induced-pain-chronification
#10
EDITORIAL
Sufang Liu, Feng Tao
Persistent postsurgical pain is a serious issue in public health, which has received increased interest in recent years. Previous studies have reported that psychological factors promote the development of chronic postsurgical pain. However, it is unclear how chronification of postsurgical pain occurs. The α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor (AMPA) phosphorylation in the central nervous system plays a critical role in synaptic plasticity and contributes to central sensitization and chronic pain development...
February 26, 2017: World Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28284169/salivary-diurnal-cortisol-profiles-in-patients-suffering-from-chronic-breathlessness-receiving-supportive-and-palliative-care-services-a-cross-sectional-study
#11
Richella Ryan, Angela Clow, Anna Spathis, Nina Smyth, Stephen Barclay, Marie Fallon, Sara Booth
Chronic breathlessness is a common source of psychological and physical stress in patients with advanced or progressive disease, suggesting that hypothalamic-pituitary-adrenal (HPA) axis dysregulation may be prevalent. The aim of this study was to measure the salivary diurnal cortisol profile in patients receiving supportive and palliative care for a range of malignant and non-malignant conditions and to compare the profile of those experiencing moderate-to-severe disability due to breathlessness against that of patients with mild/no breathlessness and that of healthy controls...
January 27, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28280318/the-relationship-between-the-spiritual-attitude-of-the-family-caregivers-of-older-patients-with-stroke-and-their-burden
#12
Razieh Torabi Chafjiri, Nasrin Navabi, Abbas Shamsalinia, Fatemeh Ghaffari
INTRODUCTION: Stroke is a chronic condition that necessitates multidimensional and overwhelming care. The caregivers of stroke patients are faced with various stressors that can threaten different aspects of their health, especially their mental health. Spiritual attitude and being spiritually oriented contribute significantly to mental health and can be used as a strategy for adapting to the stressful events that are part of the role of caregiving. This study was therefore conducted to investigate the relationship between the spiritual attitude of the family caregivers of older patients with stroke and their burden...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28277549/the-final-oral-ebola-vaccine-trial-on-captive-chimpanzees
#13
Peter D Walsh, Drishya Kurup, Dana L Hasselschwert, Christoph Wirblich, Jason E Goetzmann, Matthias J Schnell
Could new oral vaccine technologies protect endangered wildlife against a rising tide of infectious disease? We used captive chimpanzees to test oral delivery of a rabies virus (RABV) vectored vaccine against Ebola virus (EBOV), a major threat to wild chimpanzees and gorillas. EBOV GP and RABV GP-specific antibody titers increased exponentially during the trial, with rates of increase for six orally vaccinated chimpanzees very similar to four intramuscularly vaccinated controls. Chimpanzee sera also showed robust neutralizing activity against RABV and pseudo-typed EBOV...
March 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28276947/assessment-of-depression-anxiety-quality-of-life-and-coping-in-long-standing-multiple-endocrine-neoplasia-type-2-patients
#14
Karine Candido Rodrigues, Rodrigo Almeida Toledo, Flavia Lima Coutinho, Adriana Bezerra Nunes, Rui M B Maciel, Ana Oliveira Hoff, Marcos C Tavares, Sergio P A Toledo, Delmar Muniz Lourenço
BACKGROUND: Scarce data on psychological harm in multiple endocrine neoplasia type 2 (MEN2) are available. OBJECTIVES: To assess anxiety, depression, quality of life and coping in long-standing MEN2 patients. PATIENTS AND METHODS: Forty-three adults (age ≥ 18 y) with clinical and genetic diagnosis of MEN2 and long-term follow-up (10.6±8.2 years; 1-33). A cross-sectional study with qualitative and quantitative psychological assessment using semi-directed interviews and HADS, EORTC QLQ C30 and MINI-MAC scales...
March 9, 2017: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/28276066/stress-vulnerability-in-adolescents-with-chronic-fatigue-syndrome-experimental-study-investigating-heart-rate-variability-and-skin-conductance-responses
#15
Katharine A Rimes, Kate Lievesley, Trudie Chalder
BACKGROUND: Stress vulnerability has been implicated in adolescent chronic fatigue syndrome (CFS), but has rarely been investigated directly. This study compared psychological and physiological responses to a laboratory social performance task in adolescents with CFS with chronic illness (asthma) and healthy control groups. METHODS: Adolescents with CFS (n = 60), adolescents with asthma (n = 31) and healthy adolescents (n = 78) completed questionnaires before and after a social performance task...
March 9, 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/28272183/incidence-intensity-and-impact-of-pain-in-recently-discharged-adult-trauma-patients-an-exploratory-study
#16
Helen Goldsmith, Kate Curtis, Andrea McCloughen
The long-term implications of pain following injury are well known; however, the immediate posthospitalization incidence and impact of pain is less understood. Inadequate pain relief during this time can delay return to work, leading to psychological stress and chronic pain. This exploratory study aimed to identify the incidence, intensity, and impact of injury-related pain in recently discharged adult trauma patients. During July to December 2014, 82 recently discharged adult trauma patients completed a questionnaire about their injury-related pain experience approximately 2 weeks posthospital discharge from a Level 1 trauma center...
March 2017: Journal of Trauma Nursing: the Official Journal of the Society of Trauma Nurses
https://www.readbyqxmd.com/read/28272133/how-well-do-we-understand-the-long-term-health-implications-of-childhood-bullying
#17
Pablo Patricio Zarate-Garza, Bridget K Biggs, Paul Croarkin, Brooke Morath, Jarrod Leffler, Alfredo Cuellar-Barboza, Susannah J Tye
Once dismissed as an innocuous experience of childhood, bullying is now recognized as having significant psychological effects, particularly with chronic exposure. Victims of bullying are at risk for a number of psychiatric disturbances, and growing evidence suggests that the pathophysiological effects of bullying, as with other forms of trauma and chronic stress, create additional health risks. We review the literature on the known sequelae of bullying, including psychiatric and physiological health effects, with a focus on implications for the victim...
March 2017: Harvard Review of Psychiatry
https://www.readbyqxmd.com/read/28270247/gut-brain-actions-underlying-comorbid-anxiety-and-depression-associated-with-inflammatory-bowel-disease
#18
Áine Abautret-Daly, Elaine Dempsey, Adolfo Parra-Blanco, Carlos Medina, Andrew Harkin
Introduction Inflammatory bowel disease (IBD) is a chronic relapsing and remitting disorder characterised by inflammation of the gastrointestinal tract. There is a growing consensus that IBD is associated with anxiety- and depression-related symptoms. Psychological symptoms appear to be more prevalent during active disease states with no difference in prevalence between Crohn's disease and ulcerative colitis. Behavioural disturbances including anxiety- and depression-like symptoms have also been observed in animal models of IBD...
March 8, 2017: Acta Neuropsychiatrica
https://www.readbyqxmd.com/read/28260620/recovery-trajectories-for-long-term-health-related-quality-of-life-following-a-road-traffic-crash-injury-results-from-the-uq-support-study
#19
Justin Kenardy, Michelle Heron-Delaney, Joan Hendrikz, Jacelle Warren, Shannon L Edmed, Erin Brown
BACKGROUND: Diminished physical and mental health-related quality of life (HRQoL) is a common consequence of road traffic crash (RTC) injury. This study aimed to (a) determine the probable recovery trajectories in physical and mental HRQoL; (b) examine the impact of posttraumatic stress disorder (PTSD) on HRQoL scores within these trajectory groups; and (c) examine the influence of predictor covariates on trajectory group membership. METHODS: 336 (63% female, Mage =44...
February 28, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28260499/regulatory-role-of-g-protein-coupled-receptors-in-pancreatic-cancer-development-and-progression
#20
Hildegard M Schuller
BACKGROUND: Pancreatic cancer is the fourth leading cause of cancer deaths with incidence rising and a high mortality rate. Smoking, psychological stress, diabetes, pancreatitis and alcohol abuse are known risk factors for pancreatic cancer. OBJECTIVE: Targeting G protein-coupled receptor signaling for the prevention and therapy of pancreatic cancer. METHOD: Review of published literature. RESULTS AND CONCLUSION: All known risk factors for pancreatic cancer cause hyperactive cyclic adenosine monophosphate (cAMP) signaling via cancer stimulating Gαs-coupled beta-adrenergic and prostaglandin E2 receptors and/or by suppressing signaling via inhibitory Gαi-coupled GABAB-receptors...
March 3, 2017: Current Medicinal Chemistry
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