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Chronic psychological stress

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https://www.readbyqxmd.com/read/29325481/stress-management-and-the-role-of-rhodiola-rosea-a-review
#1
Ion-George Anghelescu, David Edwards, Erich Seifritz, Siegfried Kasper
OBJECTIVE: Stress describes the physiological reaction to threat or pressure, which manifests as physical symptoms of exhaustion or energy loss and psychological symptoms, including irritability or tension. If untreated, chronic stress or burnout may develop, both are areas of unmet medical need. Evidence-based treatment and prevention measures are needed. METHODS: Prevention strategies and existing treatment options for stress-related symptoms were evaluated to establish criteria for an adequate pharmacological approach to stress...
January 11, 2018: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/29323526/psychological-and-neural-correlates-of-embitterment-in-old-age
#2
Simone Kühn, Sandra Düzel, Johanna Drewelies, Denis Gerstorf, Ulman Lindenberger, Jürgen Gallinat
OBJECTIVE: Posttraumatic embitterment disorder (PTED) comprises a stress-related response to a negative life event that violates the belief system of the individual. Characteristic symptoms involve repeated intrusive thoughts, emotional arousal when reminded of the event, and decreases in well-being. METHOD: Within the scope of the present study, embitterment was treated as a continuous rather than categorical concept, and we investigated its psychological and brain structural correlates in a sample of healthy older adults...
January 2018: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/29323522/demoralization-and-embitterment
#3
Maria Giulia Nanni, Rosangela Caruso, Silvana Sabato, Luigi Grassi
OBJECTIVE: Individuals may experience a wide range of psychological reactions in response to negative life events. Even if events that threaten life have been always played a central role in research, recent studies have outlined that experiences, considered exceptional but part of the human existence (e.g., divorce, unemployment, or chronic illness) may also lead individuals to experience enduring emotional states of suffering. Demoralization has been substantially described as an important condition occurring in response to stressful events, while a recent interest is growing on embitterment as a common reaction...
January 2018: Psychological Trauma: Theory, Research, Practice and Policy
https://www.readbyqxmd.com/read/29320976/the-mediational-role-of-helplessness-in-psychological-outcomes-in-systemic-lupus-erythematosus
#4
S D Mills, D Azizoddin, S Gholizadeh, G Z Racaza, P M Nicassio
Objective Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can result in disability and psychological distress. Although pain has been associated with depressive symptomatology and stress in SLE, a paucity of theoretical models have been used to explain the relationship between pain and psychological distress in this population. Thus, the present study examined helplessness as a mediator of the relationship between pain and psychological distress among patients with SLE. Methods Multiple mediation analysis was used to examine the hypothesis that learned helplessness mediates the relationship between pain and symptoms of anxiety, depression, and stress in a sample of patients with SLE ( N = 136) receiving medical care at Cedars Sinai Medical Center...
January 1, 2018: Lupus
https://www.readbyqxmd.com/read/29317595/hippocampal-metabolic-differences-implicate-distinctions-between-physical-and-psychological-stress-in-four-rat-models-of-depression
#5
Lanxiang Liu, Xinyu Zhou, Yuqing Zhang, Juncai Pu, Lining Yang, Shuai Yuan, Libo Zhao, Chanjun Zhou, Hanping Zhang, Peng Xie
Major depressive disorder (MDD) is a heterogeneous and multi-factorial disorder, and the underlying molecular mechanisms remain largely unknown. However, many studies have indicated that the molecular mechanisms underlying depression in response to different stress may differ. After screening, 28-30 rats were included in each model of depression (chronic unpredictable mild stress (CUMS); learned helplessness (LH); chronic restraint stress (CRS); or social defeat (SD)). Non-targeted gas chromatography-mass spectrometry was used to profile the metabolic changes in the hippocampus...
January 10, 2018: Translational Psychiatry
https://www.readbyqxmd.com/read/29316582/-burnout-in-intensive-care
#6
Andrej Michalsen, Andreas Hillert, Andreas Schießl, Dominik Hinzmann
Both acute crises and chronically incriminating circumstances in people's lives may lead to their being afflicted by psychological and somatic ailments. "Burnout" has been coined and established as the term for chronic occupational strain. Many professions claim to be extraordinarily affected by burnout, amongst others physicians and nurses, especially those working in anaesthesiology and critical care. Usually assessed with the Maslach Burnout Inventary, the prevalence of moderate or severe burnout in these areas is estimated at about 30 % amongst nurses and about 40 % to 50 % amongst physicians...
January 2018: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29311652/adult-generated-neurons-born-during-chronic-social-stress-are-uniquely-adapted-to-respond-to-subsequent-chronic-social-stress
#7
Zurine De Miguel, Ursula Haditsch, Theo D Palmer, Arantza Azpiroz, Robert M Sapolsky
Chronic stress is a recognized risk factor for psychiatric and psychological disorders and a potent modulator of adult neurogenesis. Numerous studies have shown that during stress, neurogenesis decreases; however, during the recovery from the stress, neurogenesis increases. Despite the increased number of neurons born after stress, it is unknown if the function and morphology of those neurons are altered. Here we asked whether neurons in adult mice, born during the final 5 days of chronic social stress and matured during recovery from chronic social stress, are similar to neurons born with no stress conditions from a quantitative, functional and morphological perspective, and whether those neurons are uniquely adapted to respond to a subsequent stressful challenge...
January 8, 2018: Molecular Psychiatry
https://www.readbyqxmd.com/read/29310718/metacognitive-therapy-vs-eye-movement-desensitization-and-reprocessing-for-posttraumatic-stress-disorder-study-protocol-for-a-randomized-superiority-trial
#8
Hans M Nordahl, Joar Øveraas Halvorsen, Odin Hjemdal, Mimoza Rrusta Ternava, Adrian Wells
BACKGROUND: The psychological treatment of choice for patients with severe posttraumatic stress disorder (PTSD) is cognitive behavioural exposure therapy or Eye Movement Desensitisation Reprocessing (EMDR). Whilst these are the most effective treatments, approximately 30-45% of the patients show no significant improvements and follow-up data are sparse. Furthermore, a proportion of patients with severe trauma does not benefit or avoid exposure therapy due to the potential to overwhelm them...
January 8, 2018: Trials
https://www.readbyqxmd.com/read/29306937/the-effects-of-stress-and-meditation-on-the-immune-system-human-microbiota-and-epigenetics
#9
Ayman Mukerji Househam, Christine Tara Peterson, Deepak Chopra
Context • Globally, more than 25% of individuals are affected by anxiety and depression disorders. Meditation is gaining popularity in clinical settings and its treatment efficacy is being studied for a wide array of psychological and physiological ailments. An exploration of stress physiology is an essential precursor to delineation of the mechanisms underlying the beneficial effects of meditation practices. Objective • The review outlines a model of interconnected physiological processes that might support the continued inclusion and expansion of meditation in the treatment of diverse medical conditions and to investigate the role that gut microbiota may play in realizing well-being through meditation...
October 2017: Advances in Mind-body Medicine
https://www.readbyqxmd.com/read/29301763/mental-disorder-in-children-with-physical-conditions-a-pilot-study
#10
Alexandra Butler, Ryan J Van Lieshout, Ellen Louise Lipman, Harriet L MacMillan, Andrea Gonzalez, Jan Willem Gorter, Kathy Georgiades, Kathy N Speechley, Michael H Boyle, Mark A Ferro
OBJECTIVES: Methodologically, to assess the feasibility of participant recruitment and retention, as well as missing data in studying mental disorder among children newly diagnosed with chronic physical conditions (ie, multimorbidity). Substantively, to examine the prevalence of multimorbidity, identify sociodemographic correlates and model the influence of multimorbidity on changes in child quality of life and parental psychosocial outcomes over a 6-month follow-up. DESIGN: Prospective pilot study...
January 3, 2018: BMJ Open
https://www.readbyqxmd.com/read/29286498/psychosocial-state-of-the-adult-evacuees-and-risk-factors-of-negative-change
#11
V O Buzunov, K M Loganovsky, L I Krasnikova, M O Bomko, Yu M Belyayev, Zh S Yaroshenko, T E Domashevska
Numerous scientific studies have been carried out since the ChNPP accident indicating that the last one has caused a severe psychosocial stress in survivors. Population of radioactively contaminated territories, people migrated from the areas of strict radiation control, and accident consequences clean up participants in 1986 1987 were covered by the conducted research projects. Nature of the stress herewith is polygenic and includes factors directly related to the Chernobyl catastrophe, and factors being a result of social and economic circumstances...
December 2017: Problemy Radiat︠s︡iĭnoï Medyt︠s︡yny Ta Radiobiolohiï
https://www.readbyqxmd.com/read/29283816/impact-of-disease-disclosure-on-stigma-an-experimental-investigation-of-college-students-reactions-to-inflammatory-bowel-disease
#12
Jacob A Rohde, Yue Wang, Chelsea M Cutino, Bonnie K Dickson, Marisa C Bernal, Serena Bronda, Aizhou Liu, Sai Indira Priyadarshini, Ling Guo, Jason S Reich, Francis A Farraye
Inflammatory bowel disease (IBD) is a serious chronic illness that affects 1 in 200 people in the United States with the majority of new cases of IBD diagnosed in young people under the age of 35. Despite the growing number of people who are diagnosed each year, the consequences of health-related stigma faced by young people grappling with the effects of IBD are understudied. This experimental investigation explored the existence of enacted stigma among college students, a population that faces many social and psychological challenges due to the added emotional stresses brought about by the transition from high school and adolescence to college and adulthood...
December 28, 2017: Journal of Health Communication
https://www.readbyqxmd.com/read/29275100/metabolic-and-vascular-pattern-in-medial-pterygoid-muscle-is-altered-by-chronic-stress-in-an-animal-model-of-hypodontia
#13
Rodrigo Alberto Restrepo Fernández, Yamba Carla Lara Pereira, Daniela Mizusaki Iyomasa, Ricardo Alexandre Calzzani, Christie Ramos Andrade Leite-Panissi, Mamie Mizusaki Iyomasa, Glauce Crivelaro Nascimento
Psychological stress is an important perpetuating, worsening and risk factor for temporomandibular disorders of muscular or articular origin. Occlusion instability, by the way, is considered a risk factor of this pathology and can be reproduced in some experimental animal models. The exact physiologic mechanism underlying these relations however, remains unclear. Our purpose was to test the hypothesis that chronic stress and unilateral exodontia induce metabolic and vascular changes in the medial pterygoid muscle of rats...
December 21, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/29261731/time-course-of-adiponectin-and-its-relationship-to-psychological-aspects-in-patients-with-anorexia-nervosa-during-inpatient-treatment
#14
Magdalena Buckert, Esther Stroe-Kunold, Hans-Christoph Friederich, Daniela Wesche, Christiane Walter, Stefan Kopf, Joe J Simon, Wolfgang Herzog, Beate Wild
OBJECTIVE: The protein hormone adiponectin promotes metabolic and psychological health. The aim of the study was to track changes in adiponectin levels in response to weight gain and to assess associations between adiponectin and psychological aspects in patients with anorexia nervosa (AN). METHODS: To investigate if adiponectin levels depend on AN severity, data were assessed from 11 inpatients with a very low body mass index (BMI) and a high chronicity (high severity group; HSS), and nine with less severe symptoms (LSS)...
2017: PloS One
https://www.readbyqxmd.com/read/29239280/perceived-injustice-and-its-correlates-after-mild-traumatic-brain-injury
#15
Grant L Iverson, Douglas P Terry, Justin E Karr, William Panenka, Noah D Silverberg
Perceived injustice is a belief that one has been treated unfairly, disrespectfully, and is suffering unnecessarily as a result of another person's actions. Perceived injustice predicts chronic disability after musculoskeletal injury, but to our knowledge, has not been empirically studied in people with mild traumatic brain injuries (MTBIs). We examined perceived injustice and its correlates in patients who were slow to recover from MTBI. Patients (N=102) were recruited from four concussion clinics. The sample was on average 41...
December 14, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29238497/the-role-of-anxiety-and-depression-on-acceptance-and-action-considering-emotional-schemas-in-diabetics-of-birjand-iran
#16
Elham Imani, Fatemeh Shahabizadeh, Alireza Mahmoodirad
Background: Diabetes is one of the most common noncommunicable diseases around the world that accompanies assorted psychiatric disorders including anxiety and depression due to being chronic. Objective: The aim of this study was to evaluate the effect of anxiety and depression on acceptance and action, considering emotional schemas of diabetics referring to diabetes clinics of health centers in Birjand, Iran. Methods: This study was conducted in 2016 and was a correlational study with a structural equation modeling approach...
October 2017: Electronic Physician
https://www.readbyqxmd.com/read/29237322/global-variation-in-diurnal-cortisol-rhythms-evidence-from-garisakangforager-horticulturalists-of-lowland-papua-new-guinea
#17
Samuel S Urlacher, Melissa A Liebert, Martina Konečná
The hypothalamic-pituitary-adrenal (HPA) axis represents an important and evolutionarily ancient biological pathway linking physical and psychological stressors with human health. Despite considerable research exploring the physiological stress response among developed populations, few studies have examined HPA activity in non-industrialized contexts, restricting understanding of variation in human stress reactivity across global socio-ecological diversity. The present study addresses this shortcoming by investigating diurnal cortisol rhythms among Garisakang forager-horticulturalists of remote, lowland Papua New Guinea...
December 13, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/29236043/stress-induced-endocrine-and-immune-dysfunctions-in-caregivers-of-people-with-eating-disorders
#18
Ángel Romero-Martínez, Luis Moya-Albiol
Caregivers have to cope repeatedly with acute stressors in their daily lives, and this is associated with disturbances in the hypothalamic-pituitary-adrenal (HPA) axis and the immune system. Such disturbances could contribute to the development of health problems in informal caregivers of people with chronic illnesses, such as eating disorders (EDs). The main objective of this study was to examine endocrine (salivary cortisol levels (Csal)), immune (immunoglobulin-A (IgA)), and psychological (anxiety, mood, and anger feelings) responses to an acute psychological stressor in a sample of informal caregivers of individuals with EDs compared to a sample of non-caregivers...
December 13, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29234278/effects-of-social-defeat-stress-on-sleep-in-mice
#19
Fiona Henderson, Vincent Vialou, Salah El Mestikawy, Véronique Fabre
Stress plays a key role in the development of psychiatric disorders and has a negative impact on sleep integrity. In mice, chronic social defeat stress (CSDS) is an ethologically valid model of stress-related disorders but little is known about its effects on sleep regulation. Here, we investigated the immediate and long-term effects of 10 consecutive days of social defeat (SD) on vigilance states in C57Bl/6J male mice. Social behavior was assessed to identify susceptible mice, i.e., mice that develop long-lasting social avoidance, and unsusceptible mice...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/29229502/sodium-butyrate-abolishes-lipopolysaccharide-induced-depression-like-behaviors-and-hippocampal-microglial-activation-in-mice
#20
Yosuke Yamawaki, Norika Yoshioka, Kanako Nozaki, Hikaru Ito, Keisuke Oda, Kana Harada, Satomi Shirawachi, Satoshi Asano, Hidenori Aizawa, Shigeto Yamawaki, Takashi Kanemastu, Hiroyuki Akagi
Patients with major depressive disorder have elevated peripheral inflammation; the degree of this increase correlates with the severity of the disorder. Chronic psychological stress increases pro-inflammatory cytokines and promotes microglial activation, leading to stress vulnerability. Epigenetics, including DNA methylation and histone modification, are also related to the pathophysiology of major depressive disorder. Sodium butyrate (SB), a histone deacetylase inhibitor, exerts an antidepressant effect by altering gene expression in the hippocampus...
December 8, 2017: Brain Research
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