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https://www.readbyqxmd.com/read/29774003/disrupted-spontaneous-neural-activity-related-to-cognitive-impairment-in-postpartum-women
#1
Jin-Xia Zheng, Yu-Chen Chen, Huiyou Chen, Liang Jiang, Fan Bo, Yuan Feng, Wen-Wei Tang, Xindao Yin, Jian-Ping Gu
Purpose: Prior research has demonstrated that the postpartum period is associated with an increased risk of cognitive impairment. This study aims to investigate whether disrupted spontaneous neural activity exists in postpartum women without depression using resting-state functional magnetic resonance imaging (rs-fMRI) and to detect the relationship between these abnormalities and cognitive impairment. Materials and Methods: Postpartum women ( n = 22) were compared with age- and education-matched nulliparous women ( n = 23) using rs-fMRI...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29769123/obesity-impairs-male-fertility-through-long-term-effects-on-spermatogenesis
#2
Yan-Fei Jia, Qian Feng, Zheng-Yan Ge, Ying Guo, Fang Zhou, Kai-Shu Zhang, Xiao-Wei Wang, Wen-Hong Lu, Xiao-Wei Liang, Yi-Qun Gu
OBJECTIVE: This study aimed to investigate the effect and possible underlying mechanisms of high-fat diet-induced obesity on spermatogenesis in male rats. METHODS: A total of 45 male rats were randomly divided into control (n = 15, normal diet) and obesity groups (n = 30, high-fat diet) and were fed for 16 weeks. Body weight and organ indexes were determined after sacrifice. Indicators of reproductive function, including sperm count, sperm motility, apoptosis of spermatogenic cells, and oxidative stress levels, were measured...
May 16, 2018: BMC Urology
https://www.readbyqxmd.com/read/29768092/are-only-infants-held-more-often-on-the-left-if-so-why-testing-the-attention-emotion-hypothesis-with-an-infant-a-vase-and-two-chimeric-tests-one-emotional-one-not
#3
Lauren Julius Harris, Rodrigo A Cárdenas, Nathaniel D Stewart, Jason B Almerigi
Most adults, especially women, hold infants and dolls but not books or packages on the left side. One reason may be that attention is more often leftward in response to infants, unlike emotionally neutral objects like books and packages. Women's stronger bias may reflect greater responsiveness to infants. Previously, we tested the attention hypothesis by comparing women's side-of-hold of a doll, book, and package with direction-of-attention on the Chimeric Faces Test (CFT) [Harris, L. J., Cárdenas, R. A...
May 16, 2018: Laterality
https://www.readbyqxmd.com/read/29759022/compassion-focused-therapy-for-trauma-in-people-with-intellectual-disabilities-a-conceptual-review
#4
Megan Cowles, Cathy Randle-Phillips, Andrew Medley
Trauma exposure and post-traumatic stress disorder are more prevalent in people with intellectual disabilities (PWID) than in the general population, yet the evidence base for trauma interventions in this population is sparse. Compassion-focused therapy (CFT) may be particularly well-suited to PWID for a number of reasons, including its adaptability to different developmental levels. PWID are more likely to have issues with self-relating (e.g. shame and self-criticism) and attachment than the general population, two issues that are compounded by trauma and which CFT explicitly seeks to address...
January 1, 2018: Journal of Intellectual Disabilities: JOID
https://www.readbyqxmd.com/read/29752593/effects-of-kallidinogenase-in-patients-undergoing-vitrectomy-for-diabetic-macular-edema
#5
Yuki Yoshizumi, Zaigen Ohara, Hitoshi Tabuchi, Hitomi Sumino, Yukiko Maeda, Hideki Mochizuki, Ken Yamane, Yoshiaki Kiuchi
PURPOSE: To evaluate the effectiveness of the combination of vitrectomy with kallidinogenase for diabetic macular edema (DME). METHODS: This study was designed as a prospective, randomized, multicenter study comparing 19 eyes of 19 patients who received 150 units of kallidinogenase administered a day for 52 weeks from the day after vitrectomy (study group) with 20 eyes of 20 patients who received no kallidinogenase (control group). The main outcome measurements included logMAR visual acuity and central foveal thickness (CFT) before surgery and at 3, 6, 9, and 12 months after vitrectomy...
May 12, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29742951/carotid-flow-as-a-surrogate-for-cardiac-output-measurement-in-hemodynamically-stable-participants
#6
Marian Sidor, Lalith Premachandra, Bishoy Hanna, Nanda Nair, Amit Misra
OBJECTIVE: Evaluation of common carotid artery (CCA) blood flow can provide valuable information regarding the hemodynamic status of a patient. Utilizing ultrasound, we aimed to evaluate the correlation between cardiac output and different hemodynamic parameters in the CCA, namely systolic carotid flow (SCF), corrected flow time (CFT), and total carotid flow (TCF). METHODS: We studied a pilot sample of 20 healthy volunteers. Hemodynamic parameters were collected in the right CCA and the heart at rest (baseline), 1-leg compression, 2-leg compression, and passive leg raise...
January 1, 2018: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/29736870/can-we-predict-thrombotic-tendency-in-rheumatoid-arthritis-a-thromboelastographic-analysis-with-rotem
#7
Sümeyye Merve Türk, Döndü Üsküdar Cansu, Hava Üsküdar Teke, Timuçin Kaşifoğlu, O Meltem Akay, Muzaffer Bilgin, Cengiz Korkmaz
The higher incidence of arterial and venous events is well established in patients with rheumatoid arthritis (RA). Our aim here was to investigate whether there is a prothrombotic state in RA patients by using rotational thromboelastometry (ROTEM) method and to demonstrate whether the disease variables play a role in this process. A total of 85 patients who met the 2010 RA classification criteria were consecutively included in the study. The patients with RA who have been using antiaggregant, anticoagulant, or nonsteroidal anti-inflammatory drugs (NSAIDs) and had a history of arterial or venous thromboembolism were excluded from the study...
May 7, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29734979/executive-and-visuospatial-dysfunction-in-patients-with-primary-restless-legs-syndrome-willis-ekbom-disease-study-of-a-chinese-population
#8
Gen Li, Huidong Tang, Jie Chen, Xuemei Qi, Shengdi Chen, Jianfang Ma
STUDY OBJECTIVES: The aim of the study was to investigate the cognitive function of patients with primary restless legs syndrome/Willis-Ekbom disease (RLS/WED) in a Chinese population. METHODS: A total of 40 patients with RLS/WED who were drug naïve and 40 controls, matched by age, sex, and educational level, were evaluated by cognitive function assessments, including the Chinese version of the Mini-Mental State Examination (MMSE-C), clock drawing test (CDT), Auditory Verbal Learning Test (AVLT), Rey-Osterrieth Complex Figure Test (CFT), and Stroop Color Word Test (SCWT)...
April 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29726662/-value-of-the-serum-free-testosterone-level-in-detecting-erectile-dysfunction
#9
Zi-Bin Lin, Jun-Hong Deng, Liang-Liang Huang, Hua Shi, Jian-Ming Liu, Bin Ou-Yang, Jing-Xuan Xie
Objective: To investigate the values of serum calculated free testosterone (cFT), testosterone secretion index (TSI), and free testosterone index (FTI) in the diagnosis of ED with androgen deficiency by observing their changes in the patient. METHODS: We conducted this study among 185 men complaining of ED and 35 20-40 years old healthy males presenting at the clinic for premarital medical checkup. We asked them about their medical history, to fill in the International Index of Erectile Function (IIEF-5) Questionnaire, and to complete the nocturnal penile tumescence (NPT) test...
September 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29719639/retinal-nerve-fiber-layer-changes-following-primary-retinal-detachment-repair-with-silicone-oil-tamponade-and-subsequent-oil-removal
#10
Brijesh Takkar, Rajvardhan Azad, Neha Kamble, Shorya Azad
Purpose: To evaluate the correlation between the retinal nerve fiber layer (RNFL), particularly the temporal RNFL (TRNFL), and visual outcomes following surgery for rhegmatogenous retinal detachment (RRD). Methods: This retrospective study was performed at a tertiary center; 32 patients underwent single and successful vitrectomy for total RRD using silicone oil as tamponade. Data were collected after oil removal. RNFL thickness and central foveal thickness (CFT) were measured using spectral domain optical coherence tomography...
April 2018: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/29716485/the-effects-of-haemodilution-with-succinylated-gelatin-solution-on-coagulation-in-vitro-as-assessed-by-thromboelastometry-and-impedance-multiple-electrode-aggregometry
#11
Pca Kam, S Varanasi, K X Yang
We investigated the in vitro viscoelastic changes of progressive haemodilution with succinylated gelatin (SG) solution compared with normal saline (NS) using rotational thromboelastometry (ROTEM®). Whole blood (WB) samples obtained from 20 healthy volunteers were diluted in vitro with SG solution or NS by 10%, 20% and 40%. Fibrinogen concentration and ROTEM (EXTEM, FIBTEM) variables including coagulation time (CT), clot formation time (CFT), α-angle, and maximum clot firmness (MCF) were measured in the undiluted sample and at each degree of haemodilution...
May 2018: Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/29712637/efficacy-of-non-fovea-sparing-ilm-peeling-for-symptomatic-myopic-foveoschisis-with-and-without-macular-hole
#12
Amer Hamad Al-Badawi, Mohamad Amr Salah Eddin Abdelhakim, Tamer Ahmed Macky, Hassan Aly Mortada
AIM: To study anatomical and visual outcomes of pars plana vitrectomy (PPV) with non-fovea-sparing (entire) internal limiting membrane (ILM) peeling in eyes with myopic foveoschisis (MF). METHODS: Prospective interventional case series of eyes undergoing PPV with entire ILM peeling for symptomatic MF. MAIN OUTCOME MEASURES: Preoperative spectral domain optical coherence tomography (SD - OCT) epiretinal membrane, anomalous posterior vitreous detachment, vitreoschisis and postoperative changes in SD-OCT central foveal thickness (CFT), ellipsoid zone defect, foveal detachment (FD), macular hole (MH) diameter (if present) and best-corrected visual acuity (BCVA) in logarithm of the minimum angle of resolution (logMAR)...
April 30, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29708829/the-impact-of-testosterone-replacement-therapy-on-glycemic-control-vascular-function-and-components-of-the-metabolic-syndrome-in-obese-hypogonadal-men-with-type-2-diabetes
#13
Kristina Groti, Ivan Žuran, Blaž Antonič, Lidija Foršnarič, Marija Pfeifer
OBJECTIVE: This study set out to assess effects of testosterone replacement therapy (TRT) on parameters of metabolic syndrome and vascular function in obese hypogonadal males with type 2 diabetes mellitus (DM2). STUDY DESIGN: Fifty-five obese hypogonadal diabetic males on oral hypoglycemic treatment were enrolled into this one-year, double-blind, randomized, placebo-controlled clinical study. Group T (n = 28) was treated with testosterone undecanoate (1000 mg i...
April 30, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29704382/establishing-the-cut-off-values-of-androgen-markers-in-the-assessment-of-polycystic-ovarian-syndrome
#14
R N D Nadaraja, P Sthaneshwar, N Razali
INTRODUCTION: Hyperandrogenism remains as one of the key features in Polycystic Ovarian Syndrome (PCOS) and can be assessed clinically or determined by biochemical assays. Hirsutism is the most common clinical manifestation of hyperandrogenism. The clinical assessment is subjected to wide variability due to poor interobserver agreement and multiple population factors such as ethnic variation, cosmetic procedures and genetic trait. The difficulty in resolving the androgen excess biochemically is due to a lack of consensus as to which serum androgen should be measured for the diagnosis of PCOS...
April 2018: Malaysian Journal of Pathology
https://www.readbyqxmd.com/read/29680652/technical-note-improving-modeling-of-coagulation-curd-firming-and-syneresis-of-sheep-milk
#15
Claudio Cipolat-Gotet, Michele Pazzola, Alessandro Ferragina, Alessio Cecchinato, Maria L Dettori, Giuseppe M Vacca
The importance of milk coagulation properties for milk processing, cheese yield, and quality is widely recognized. The use of traditional coagulation traits presents several limitations for testing bovine milk and even more for sheep milk, due to its rapid coagulation and curd firming, and early syneresis of coagulum. The aim of this technical note is to test and improve model fitting for assessing coagulation, curd firming, and syneresis of sheep milk. Using milk samples from 87 Sarda ewes, we performed in duplicate lactodynamographic testing...
April 18, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29657976/efficacy-of-additional-topical-betamethasone-in-persistent-cystoid-macular-oedema-after-carbonic-anhydrase-inhibitor-treatments-in-retinitis-pigmentosa
#16
Shohei Kitahata, Yasuhiko Hirami, Seiji Takagi, Cody Kime, Masashi Fujihara, Yasuo Kurimoto, Masayo Takahashi
Objective: We investigated the efficacy of additional topical betamethasone in persistent cystoid macular oedema (CMO) after carbonic anhydrase inhibitors (CAIs) therapy. Methods and analysis: This retrospective cohort study included 16 eyes of 10 patients with retinitis pigmentosa (RP). All patients were previously administered CAI for at least 3 months to treat CMO secondary to RP and lacking an effective reduction (≥11%) of central foveal thickness (CFT)...
2018: BMJ Open Ophthalmology
https://www.readbyqxmd.com/read/29619853/multi-modality-molecular-imaging-characteristics-of-dementia-with-lewy-bodies
#17
Zhong-Bao Gao, Wei Wang, Xing-Li Zhao, Tong Chen, Li-Ping Fu, Bai-Xuan Xu, Zhen-Fu Wang
Objective Dementia with Lewy bodies (DLB) is a common type of neurodegenerative dementia. Molecular neuroimaging using dopamine transporter (DaT), Pittsburgh compound B (PIB), and fluorodeoxyglucose (FDG) positron emission tomography (PET) has advantages in detecting dopaminergic neuron loss, abnormal amyloid β-protein deposition, and glucose metabolism changes in patients with neurodegenerative disorders. However, the multi-modality molecular imaging features of patients with DLB have rarely been reported...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29619677/genetic-and-environmental-influences-on-language-ability-in-older-adults-findings-from-the-older-australian-twins-study
#18
T Lee, A Thalamuthu, J D Henry, J N Trollor, D Ames, M J Wright, P S Sachdev
We used a sub-sample from the Older Australian Twins Study to estimate the heritability of performance on three tests of language ability: Boston Naming Test (BNT), Letter/Phonemic Fluency (FAS) and Category/Semantic Fluency (CFT) Tests. After adjusting for age, sex, education, mood, and global cognition (GC), heritability estimates obtained for the three tests were 0.35, 0.59, and 0.20, respectively. Multivariate analyses showed that the genetic correlation were high for BNT and CFT (0.61), but low for BNT and FAS (0...
April 4, 2018: Behavior Genetics
https://www.readbyqxmd.com/read/29618085/reassessing-free-testosterone-calculation-by-liquid-chromatography-tandem-mass-spectrometry-direct-equilibrium-dialysis
#19
Tom Fiers, Frederick Wu, Paolo Moghetti, Dirk Vanderschueren, Bruno Lapauw, Jean Marc Kaufman
BACKGROUND: Assessment of free testosterone (FT) might help evaluate androgen status in subjects with borderline total testosterone (T) and/or altered SHBG levels. However, validity of different methods to measure or calculate FT is matter for debate. METHODS: Serum from 183 women and 146 men was analysed using equilibrium dialysis (ED) with FT directly measured by LC/MS-MS. FT calculation was re-evaluated for the mass action law-based equation according to Vermeulen (cFT-V) , empirical equations according to Ly (cFT-L) and a recently proposed calculation based on a multi-step, dynamic, allosteric model according to Zakharov (cFT-Z)...
March 29, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29609918/treatment-outcomes-and-predicting-factors-for-diabetic-macular-edema-treated-with-ranibizumab-one-year-real-life-results-in-taiwan
#20
Tso-Ting Lai, Chung-May Yang, Chang-Hao Yang, Tzyy-Chang Ho, Yi-Ting Hsieh
PURPOSE: To report the one-year outcomes of diabetic macular edema (DME) treated with ranibizumab under a real-life setting in Taiwan, and to identify the prognostic factors. METHODS: Between July 2013 and January 2015, 119 eyes receiving intravitreal ranibizumab for DME were retrospectively recruited. Best-corrected visual acuity (BCVA) and central foveal thickness (CFT) measured with optical coherence tomography were collected at baseline and at Month 3, 6, and 12...
March 30, 2018: Journal of the Formosan Medical Association, Taiwan Yi Zhi
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