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https://www.readbyqxmd.com/read/28644761/effectiveness-of-satir-informed-family-therapy-on-the-codependency-of-drug-dependents-family-members-in-iran-a-randomized-controlled-trial
#1
Fatemeh Karimi Ahmad-Abadi, Masoomeh Maarefvand, Hakimeh Aghaei, Samaneh Hosseinzadeh, Mahboubeh Abbasi, Jagdish Khubchandani
PURPOSE: Social workers in substance abuse treatment settings are responsible for involving families in treatment program to improve family functioning. The effectiveness of available interventions in treating codependency of family members of drug users in Iran is not well explored. We evaluated the effectiveness of the Satir communication family therapy (CFT) in healing codependency of drug dependents' family members in Tehran, Iran. METHODS: The intervention group participants (n = 27) received a seven-session social work intervention with CFT approach and the control group (n = 26) received treatment as usual...
June 23, 2017: Journal of Evidence-informed Social Work
https://www.readbyqxmd.com/read/28625215/assessing-coagulation-by-rotational-thromboelastometry-rotem-in-rivaroxaban-anticoagulated-blood-using-hemostatic-agents
#2
Jonathan Bar, Alexa David, Tarek Khader, Mary Mulcare, Christopher Tedeschi
Introduction The use of direct oral anticoagulants (DOACs) such as rivaroxaban (Xarelto) is increasingly common. However, therapies for reversing anticoagulation in the event of hemorrhage are limited. This study investigates the ability of hemostatic agents to improve the coagulation of rivaroxaban-anticoagulated blood, as measured by rotational thromboelastometry (ROTEM). Hypothesis/Problem If a chitosan-based hemostatic agent (Celox), which works independently of the clotting cascade, is applied to rivaroxaban-anticoagulated blood, it should improve coagulation by decreasing clotting time (CT), decreasing clot formation time (CFT), and increasing maximum clot firmness (MCF)...
June 19, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28616716/retinal-microstructures-are-altered-in-patients-with-idiopathic-infantile-nystagmus
#3
Jinu Han, Taekjune Lee, Jong Bok Lee, Sueng-Han Han
PURPOSE: To compare segmented retinal layer thicknesses between patients with idiopathic infantile nystagmus (IIN) and controls. METHODS: This retrospective case-control study included 66 patients with IIN and 66 age-matched controls. The retinal layers were examined using spectral domain optical coherence tomography with autosegmentation. Central foveal thickness (CFT), outer nuclear layer (ONL), and outer segment length (OSL) thickness were measured at the fovea center...
June 14, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28603574/central-retinal-vein-occlusion-in-younger-swedish-adults-case-reports-and-review-of-the-literature
#4
Elisabeth Wittström
PURPOSE: To investigate associated systemic diseases, other conditions, visual outcome, ocular complications and treatment in Swedish patients younger than 50 years with central retinal vein occlusion (CRVO) and reviewing the literature. METHODS: Twenty-two patients with CRVO, younger than 50 years, were examined with full-field electroretinography (ERG) within 3 months after a thrombotic event, or were periodically examined and were observed for at least 6 months...
2017: Open Ophthalmology Journal
https://www.readbyqxmd.com/read/28598709/an-association-between-bone-mineral-density-and-anabolic-hormones-in-middle-aged-and-elderly-men-with-prediabetes
#5
Michał Rabijewski, Lucyna Papierska, Paweł Piątkiewicz
INTRODUCTION: Prediabetes (PD) leads to reduced testosterone (T) in males, but the association between the anabolic hormones and bone mineral density (BMD) remains unknown. OBJECTIVES: We investigated an association between the anabolic hormones and BMD in middle-aged and elderly men with PD. METHODS: We investigated 84 prediabetic and 56 control men. Total T (TT), calculated free T (cFT), and dehydroepiandrosterone sulfate (DHEAS) were measured, and BMD was assessed using DXA methods...
June 9, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28591282/incidence-of-anterior-segment-neovascularization-during-intravitreal-treatment-for-macular-edema-secondary-to-central-retinal-vein-occlusion
#6
Luiz Filipe Adami Lucatto, Octaviano Magalhães-Junior, Juliana M B Prazeres, Adriano M Ferreira, Ramon A Oliveira, Nilva S Moraes, Flávio E Hirai, Mauricio Maia
Purpose: To analyze the effects of injections of intravitreal triamcinolone acetonide (IVTA) and intravitreal bevacizumab (IVB) on the incidence rates of anterior segment neovascularization (ASN) and neovascular glaucoma (NVG) in patients with macular edema secondary to central retinal vein occlusion (CRVO). Methods: In this prospective, randomized, double-masked, sham-controlled study, 35 patients with macular edema following CRVO were randomized to intravitreal bevacizumab, intravitreal triamcinolone acetonide, or sham injections during the first 6 months of the study...
March 2017: Arquivos Brasileiros de Oftalmologia
https://www.readbyqxmd.com/read/28586400/patients-with-schizophrenia-activate-behavioural-intentions-facilitated-by-counterfactual-reasoning
#7
Fernando Contreras, Auria Albacete, Cristian Tebé, Bessy Benejam, Agnes Caño, José Manuel Menchón
METHOD: The main variables assessed were: answer to complete a target task (wrong or correctly), and percentage gain in the reaction time (RT) to complete a target task correctly depending on whether the prime was a counterfactual or a neutral-control cue. These variables were assessed in 37 patients with schizophrenia and 37 healthy controls. Potential associations with clinical status and socio-demographic characteristics were also explored. RESULTS: When a counterfactual prime was presented, the probability of giving an incorrect answer was lower for the entire sample than when a neutral prime was presented (OR 0...
2017: PloS One
https://www.readbyqxmd.com/read/28581026/cross-sectional-association-between-testosterone-sex-hormone-binding-globulin-and-metabolic-syndrome-the-healthy-twin-study
#8
Heesun Moon, Inyoung Choi, Somi Kim, Hyeonyoung Ko, Jinyoung Shin, Kayoung Lee, Joohon Sung, Yun-Mi Song
OBJECTIVES: This study evaluated an association between testosterone, sex hormone-binding globulin (SHBG) and metabolic syndrome (MetS).We also evaluated the genetic and environmental influence on the association. DESIGN: Cross-sectional. SETTING: Community-based study. PARTICIPANTS: A total of 1,098 Korean adult men including 139 monozygotic twin pairs. MAIN OUTCOME MEASURE: MetS was defined using the National Cholesterol Education Program-Third Adult Treatment Panel (NCEP-ATP III) and International Diabetes Federation (IDF) criteria...
June 5, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28580297/comparison-of-natural-and-artificial-odor-lures-for-nilgai-boselaphus-tragocamelus-and-white-tailed-deer-odocoileus-virginianus-in-south-texas-developing-treatment-for-cattle-fever-tick-eradication
#9
John A Goolsby, Nirbhay K Singh, Alfonso Ortega-S, David G Hewitt, Tyler A Campbell, David Wester, Adalberto A Pérez de León
Cattle fever ticks (CFT), vectors of bovine babesiosis and anaplasmosis, were eradicated from the United States by 1943, but are frequently reintroduced from neighboring border states of Mexico via stray cattle and wildlife hosts including white-tailed deer (Odocoileus virginianus) (WTD) and nilgai antelope (Boselaphus tragocamelus). Nilgai antelope are exotic bovids from India that are hosts of CFT, have large home ranges as compared to WTD, thus have the potential to spread CFT through the landscape. Currently, there are no methods to control CFT on nilgai...
August 2017: International Journal for Parasitology. Parasites and Wildlife
https://www.readbyqxmd.com/read/28580031/the-meaning-of-voices-in-understanding-and-treating-psychosis-moving-towards-intervention-informed-by-collaborative-formulation
#10
REVIEW
Aoife Lonergan
From a medical perspective, hearing voices is perceived as a symptom of mental illness and their content as largely irrelevant. The effectiveness of antipsychotic medication has made it central to the treatment of psychosis. However pharmacological treatment alone is rarely sufficient for this disabling condition. This review examined the feasibility of formulating an understanding of the meaning of voices in psychosis to inform intervention. Examination of the literature demonstrated the need for a paradigm shift to a recovery model, drawing on biopsychosocial factors in formulating an understanding of the meaning of voices in the context of a person's life...
May 2017: Europe's journal of psychology
https://www.readbyqxmd.com/read/28553669/simultaneous-dexamethasone-intravitreal-implant-and-anti-vegf-therapy-for-neovascular-age-related-macular-degeneration-resistant-to-anti-vegf-monotherapy
#11
Bozho Todorich, Aristomenis Thanos, Yoshihiro Yonekawa, Gerta Mane, Madeleine Hasbrook, Benjamin J Thomas, Maria A Woodward, George A Williams, Antonio Capone, Jeremy D Wolfe, Lisa J Faia, Tarek S Hassan
PURPOSE: To evaluate the efficacy of a dexamethasone intravitreal implant in combination with intravitreal anti-VEGF agents for treatment resistant neovascular age-related macular degeneration (nvAMD). METHODS: This study was designed as a single-center, retrospective interventional case series. Consecutive patients with treatment-resistant nvAMD underwent simultaneous combined injection of anti-VEGF agent and dexamethasone intravitreal implant. Eighteen patients with mean age of 81...
2017: J Vitreoretin Dis
https://www.readbyqxmd.com/read/28539090/development-and-application-of-the-compression-frictional-treatment-method-for-sterilizing-and-valorizing-organic-waste
#12
Allison Talley, Robert Heimann, Stergios Vakalis
Confined animal feeding operations are producing large amounts of organic waste with large fractions being mixtures of manure and sawdust. On one hand, the inhomogeneity of the material and the high water content restrict the optimal application of thermal treatment methods. On the other hand, the high concentration of bacteria in these mixed waste streams is an issue of concern. This study introduces a novel process for treating manure and woody biomass mixtures and upgrading them into valuable products. It is defined as compression frictional treatment (CFT) and takes place continuously in a rotary compression unit...
June 6, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28525329/thromboelastographic-profile-of-goat-blood-after-the-experimental-injury-of-the-femoral-artery-and-use-of-quikclot-gauze-and-celox-gauze-dressings
#13
P Sobiech, Z Adamiak, P Holak, P Jastrzębski, J Rogowski, M Brzeziński, K Bury, M Jałyński, W Baumgartner
The aim of this study was to evaluate the suitability of thromboelastometry for the analysis of blood test results in goats after the use of hemostatic dressings to control massive bleeding. The study was carried out on 12 goats, 6 animals in each of two subgroups. In all experimental animals incision of the femoral artery was performed, and bleeding was controlled with QuikClot gauze in the first group and Celox gauze in the second group. Dressings were applied for 60 minutes. Blood samples for thromboelastometry were collected from the jugular vein before the incision and 60 min after the application of a dressing...
March 28, 2017: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28504877/illuminating-superoxide-anion-and-ph-enhancements-in-apoptosis-of-breast-cancer-cells-induced-by-mitochondrial-hyperfusion-using-a-new-two-photon-fluorescence-probe
#14
Wen Zhang, Xin Wang, Ping Li, Haibin Xiao, Wei Zhang, Hui Wang, Bo Tang
Mitochondrial morphology regulated by fusion and fission processes determines mitochondrial function and cell fate. Some studies showed hyperfused mitochondria could induce apoptosis in cancer cells, but the relevant molecular mechanisms remain elusive. Superoxide (O2(•-)) and pH play vital roles in mitochondrial dysfunction and apoptosis. Therefore, it is worthwhile to explore if there is an intimate relationship between mitochondrial hyperfusion and simultaneous changes in O2(•-) and pH levels, which will be helpful to uncover relevant detailed mechanism...
May 25, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28498944/assessment-of-standard-laboratory-tests-and-rotational-thromboelastometry-for-the-prediction-of-postoperative-bleeding-in-liver-transplantation
#15
T M Dötsch, D Dirkmann, D Bezinover, M Hartmann, J W Treckmann, A Paul, F H Saner
Background.: Perioperative bleeding remains a major challenge in liver transplantation. We aimed to compare standard laboratory tests with thromboelastometry (ROTEM ® ) with regard to their ability to predict postoperative non-surgical bleeding. Methods.: Data from 243 adult liver transplant recipients from January 2012 to May 2014 were evaluated retrospectively. Upon admission to the intensive care unit, coagulation status was assessed using standard laboratory tests [prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen concentration, and platelet count] and ROTEM ® whole blood coagulation assays...
May 12, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28489770/degeneration-of-corticofugal-fibers-in-a-patient-with-primary-progressive-freezing-gait-a-case-report
#16
Jeong Pyo Seo, Min Cheol Chang
RATIONALE: To report a patient with primary progressive freezing gait (PPFG) whose degeneration of corticofugal tract (CFT) from the supplementary motor area (SMA) was demonstrated using diffusion tensor tractography (DTT). PATIENT CONCERNS: A 66-year-old woman presented with a solitary symptom of a sudden transient break on walking (i.e., freezing gait), which slowly progressed for 4 years. DIAGNOSES: Imaging evidence using magnetic resonance imaging and F-florinated-N-3-fluoropropyl-2-β-carboxymethoxy-3-β-(4-lodophenyl) nortropane positron emission tomography scanning was unremarkable, and our patient's symptom was not affected by dopamine agonist medication...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28441487/the-isomeric-preference-of-an-atypical-dopamine-transporter-inhibitor-contributes-to-its-selection-of-the-transporter-conformation
#17
Ara M Abramyan, Sebastian Stolzenberg, Zheng Li, Claus J Loland, Frank Noé, Lei Shi
Cocaine, a widely abused psychostimulant, inhibits the dopamine transporter (DAT) by trapping the protein in an outward-open conformation, whereas atypical DAT inhibitors such as benztropine have low abuse liability and prefer less outward-open conformations. Here, we use a spectrum of computational modeling and simulation approaches to obtain the underlying molecular mechanism in atomistic detail. Interestingly, our quantum mechanical calculations and molecular dynamics (MD) simulations suggest that a benztropine derivative JHW007 prefers a different stereoisomeric conformation of tropane in binding to DAT compared to that of a cocaine derivative, CFT...
May 4, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/28439440/a-comparison-of-the-effects-of-20-mannitol-and-3-nacl-on-coagulation-parameters-in-vitro-using-rotem-a-prospective-randomized-crossover-study
#18
Achmet Ali, Bilge Şencan, Pulat Akın Sabancı, Demet Altun, Aylin Tetik, Lerzan Recep Doğan, İbrahim Özkan Akıncı
OBJECTIVE: The aim of the present study is to compare the effect of 20% mannitol and 3% NaCl on blood coagulation in vitro using rotational thromboelastometry (ROTEM). METHODS: Twenty-millilitre blood samples were obtained from 15 volunteers. In each group, 2 mL blood samples were collected into both polypropylene tubes and EDTA tubes for ROTEM and hemogram analysis. After sampling, blood samples were diluted with test solutions. Group C (control): Only blood, Group M (mannitol): 7% vol 20% mannitol concentration in the blood, Group hypertonic saline (HS): 7% vol 3% hypertonic saline (NaCl) in the blood, Group M/H (mannitol and hydroxyethyl starch solutions [HES]): 6% vol 20% mannitol concentration and 8% vol HES in the blood and Group HS/H (hypertonic saline and HES): 6% vol 3% hypertonic saline concentration and 8% vol HES in the blood...
April 2017: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/28436640/intravitreal-aflibercept-for-patients-with-diabetic-macular-edema-refractory-to-bevacizumab-or-ranibizumab-analysis-of-response-to-aflibercept
#19
Yen-Yi Chen, Pei-Yao Chang, Jia-Kang Wang
PURPOSE: To investigate the short-term efficacy and safety of intravitreal aflibercept in a case series of patients with diabetic macular edema (DME) refractory to ranibizumab or bevacizumab. DESIGN: A retrospective chart review. METHODS: From September 2013 to March 2016, we identified patients with DME who developed resistance to bevacizumab or ranibizumab. Three monthly intravitreal aflibercept injections were administered in refractory cases...
May 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28431870/the-effect-of-hypertonic-saline-and-mannitol-on-coagulation-in-moderate-traumatic-brain-injury-patients
#20
Haifeng Wang, Hongshi Cao, Xiaohong Zhang, Liang Ge, Li Bie
BACKGROUND: Hyperosmolar therapy, using either hypertonic saline (HTS) or mannitol (MT), is considered the treatment of choice for intracranial hypertension, a disorder characterized by high intracranial pressure (ICP). However, hyperosmolar agents have been postulated to impair coagulation and platelet function. The aim of this study was to identify whether HTS and MT could affect coagulation in moderate traumatic brain injury (TBI) patients. METHODS: In this prospective and randomized double-blind study, we included adult patients with moderate TBI...
April 14, 2017: American Journal of Emergency Medicine
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