Kexuan Chen, Jia Yang, Fang Li, Jin Chen, Meiling Chen, Heng Shao, Chongjun He, Defang Cai, Xing Zhang, Libo Wang, Yuejia Luo, Bochao Cheng, Jiaojian Wang
Although Postpartum depression (PPD) and PPD with anxiety (PPD-A) have been well characterized as functional disruptions within or between multiple brain systems, however, how to quantitatively delineate brain functional system irregularity and the molecular basis of functional abnormalities in PPD and PPD-A remains unclear. Here, brain sample entropy (SampEn), resting-state functional connectivity (RSFC), transcriptomic and neurotransmitter density data were used to investigate brain functional system irregularity, functional connectivity abnormalities and associated molecular basis for PPD and PPD-A...
April 2024: Human Brain Mapping