keyword
MENU ▼
Read by QxMD icon Read
search

DMN

keyword
https://www.readbyqxmd.com/read/28642688/lower-functional-connectivity-of-the-periaqueductal-gray-is-related-to-negative-affect-and-clinical-manifestations-of-fibromyalgia
#1
Marie-Andrée Coulombe, Keith St Lawrence, Dwight E Moulin, Patricia Morley-Forster, Mahsa Shokouhi, Warren R Nielson, Karen D Davis
Fibromyalgia (FM) syndrome is characterized by chronic widespread pain, muscle tenderness and emotional distress. Previous studies found reduced endogenous pain modulation in FM. This deficiency of pain modulation may be related to the attributes of chronic pain and other clinical symptoms experienced in patients with FM. Thus, we tested whether there is a link between the clinical symptoms of FM and functional connectivity (FC) of the periaqueductal gray (PAG), a key node of pain modulation. We acquired resting state 3T functional MRI (rsfMRI) data from 23 female patients with FM and 16 age- and sex- matched healthy controls (HC) and assessed FM symptoms with the Brief Pain Inventory (BPI), Fibromyalgia Impact Questionnaire (FIQ), Hospital Anxiety and Depression Scale (HADS) and Pain Catastrophizing Scale (PCS)...
2017: Frontiers in Neuroanatomy
https://www.readbyqxmd.com/read/28633076/resting-state-functional-connectivity-of-anterior-and-posterior-hippocampus-in-posttraumatic-stress-disorder
#2
Amit Lazarov, Xi Zhu, Benjamin Suarez-Jimenez, Bret R Rutherford, Yuval Neria
Posttraumatic stress disorder (PTSD) has been associated with altered resting-state functional connectivity (rs-FC) of several brain regions within the salience (SN) and default-mode (DMN) networks, including the hippocampus. However, most rs-FC studies have not focused primarily on the hippocampus, nor have they appreciated its structural heterogeneity, despite clear evidence for a dissociation between posterior and anterior hippocampal connectivity. Here, we examine rs-FC of anterior and posterior hippocampus with key regions in the SN (amygdala, insula, and dorsal anterior cingulate cortex/pre-supplementary motor area) and DMN (ventromedial prefrontal cortex, posterior cingulate cortex, and precuneus) previously implicated in PTSD, using a seed-based approach...
June 13, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28615426/modulation-of-intrinsic-resting-state-fmri-networks-in-women-with-chronic-migraine
#3
X Michelle Androulakis, Kaitlin Krebs, B Lee Peterlin, Tianming Zhang, Nasim Maleki, Souvik Sen, Chris Rorden, Priyantha Herath
OBJECTIVE: To evaluate the intrinsic resting functional connectivity of the default mode network (DMN), salience network (SN), and central executive network (CEN) network in women with chronic migraine (CM), and whether clinical features are associated with such abnormalities. METHODS: We analyzed resting-state connectivity in 29 women with CM as compared to age- and sex-matched controls. Relationships between clinical characteristics and changes in targeted networks connectivity were evaluated using a multivariate linear regression model...
June 14, 2017: Neurology
https://www.readbyqxmd.com/read/28608189/effect-of-catechol-o-methyltransferase-val158met-polymorphism-on-resting-state-brain-default-mode-network-after-acupuncture-stimulation
#4
Xuejuan Yang, Jie Gong, Lingmin Jin, Lin Liu, Jinbo Sun, Wei Qin
The effects of acupuncture can be characterized by clear individual differences. Several revealing studies suggest an underlying role of inherited genetic factor in interindividual variability in response to acupuncture treatment. It remains unclear, however, if the modulation of acupuncture on resting brain function is influenced by genetic factors. Catechol-o-methyltransferase (COMT) Val158Met polymorphism has been shown to regulate the resting brain network, especially in the default mode network (DMN), which is a target area that responds to acupuncture stimulation...
June 13, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28606629/neural-substrates-underlying-balanced-time-perspective-a-combined-voxel-based-morphometry-and-resting-state-functional-connectivity-study
#5
Yiqun Guo, Zhiyi Chen, Tingyong Feng
Balanced time perspective (BTP), which is defined as a mental ability to switch flexibly among different time perspectives Zimbardo and Boyd (1999), has been suggested to be a central component of positive psychology Boniwell and Zimbardo (2004). BTP reflects individual's cognitive flexibility towards different time frames, which leads to many positive outcomes, including positive mood, subjective wellbeing, emotional intelligence, fluid intelligence, and executive control. However, the neural basis of BTP is still unclear...
June 9, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28605972/resting-state-connectivity-between-default-mode-network-and-insula-encodes-acute-migraine-headache
#6
Gianluca Coppola, Antonio Di Renzo, Emanuele Tinelli, Cherubino Di Lorenzo, Marco Scapeccia, Vincenzo Parisi, Mariano Serrao, Maurizio Evangelista, Anna Ambrosini, Claudio Colonnese, Jean Schoenen, Francesco Pierelli
Background Previous functional MRI studies have revealed that ongoing clinical pain in different chronic pain syndromes is directly correlated to the connectivity strength of the resting default mode network (DMN) with the insula. Here, we investigated seed-based resting state DMN-insula connectivity during acute migraine headaches. Methods Thirteen migraine without aura patients (MI) underwent 3 T MRI scans during the initial six hours of a spontaneous migraine attack, and were compared to a group of 19 healthy volunteers (HV)...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28600679/resting-state-bold-oscillation-frequency-predicts-vigilance-task-performance-at-both-normal-and-high-environmental-temperatures
#7
Xiaopeng Song, Shaowen Qian, Kai Liu, Shuqin Zhou, Huaiqiu Zhu, Qihong Zou, Yijun Liu, Gang Sun, Jia-Hong Gao
Hyperthermia may impair vigilance functions and lead to slower reaction times (RTs) in the psychomotor vigilance task (PVT) and possibly disturbing cerebral hemodynamic rhythms. To test these hypotheses, we acquired the resting-state BOLD and cerebral blood flow (CBF) data, as well as PVTRTs from 15 participants in two simulated environmental thermal conditions (50 °C/25 °C). We adopted a data-driven method, frequency component analysis, to quantify the mean frequency of the BOLD series of each voxel. Across-subject correlation analysis was employed to detect the brain areas whose BOLD oscillation frequency was correlated with the RTs...
June 9, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28598839/functional-disintegration-of-the-default-mode-network-in-prodromal-alzheimer-s-disease
#8
Kim N H Dillen, Heidi I L Jacobs, Juraj Kukolja, Nils Richter, Boris von Reutern, Özgür A Onur, Karl-Josef Langen, Gereon R Fink
Neurodegenerative brain changes can affect the functional connectivity strength between nodes of the default-mode network (DMN), which may underlie changes in cognitive performance. It remains unclear how the functional connectivity strength of DMN nodes differs from healthy to pathological aging and whether these changes are cognitively relevant. We used resting-state functional magnetic resonance imaging to investigate the functional connectivity strength across five DMN nodes in 25 healthy controls (HC), 28 subjective cognitive decline (SCD) participants, and 25 prodromal Alzheimer's disease (AD) patients...
June 3, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28597149/the-renal-pathological-findings-in-japanese-hiv-infected-individuals-with-ckd-a-clinical-case-series-from-a-single-center
#9
Masaki Hara, Kumiko Momoki, Masamitsu Ubukata, Akihito Ohta, Akiko Tonooka, Minoru Ando
BACKGROUND: Chronic kidney diseases (CKD) have emerged as a significant cause of morbidity and mortality in patients infected with human immunodeficiency virus (HIV). However, the detailed study of renal pathological findings currently remains unclear in these Japanese patients. METHODS: A retrospective cohort study was undertaken to investigate renal pathological findings between January 1996 and July 2016. Our study included 20 Japanese HIV-infected patients with CKD; 10 cases had undergone renal biopsies, and 10 cases had undergone autopsies, respectively...
June 8, 2017: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/28590514/altered-white-matter-microarchitecture-in-the-cingulum-bundle-in-women-with-primary-dysmenorrhea-a-tract-based-analysis-study
#10
Jixin Liu, Hongjuan Liu, Junya Mu, Qing Xu, Tao Chen, Wanghuan Dun, Jing Yang, Jie Tian, Li Hu, Ming Zhang
Primary dysmenorrhea (PD), as characterized by painful menstrual cramps without organic causes, is associated with central sensitization and brain function changes. Previous studies showed the integrated role of the default mode network (DMN) in the pain connectome and its key contribution on how an individual perceives and copes with pain disorders. Here, we aimed to investigate whether the cingulum bundle connecting hub regions of the DMN was disrupted in young women with PD. Diffusion tensor imaging was obtained in 41 PD patients and 41 matched healthy controls (HC) during their periovulatory phase...
June 7, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28588476/age-related-differences-in-dynamic-interactions-among-default-mode-frontoparietal-control-and-dorsal-attention-networks-during-resting-state-and-interference-resolution
#11
Bárbara Avelar-Pereira, Lars Bäckman, Anders Wåhlin, Lars Nyberg, Alireza Salami
Resting-state fMRI (rs-fMRI) can identify large-scale brain networks, including the default mode (DMN), frontoparietal control (FPN) and dorsal attention (DAN) networks. Interactions among these networks are critical for supporting complex cognitive functions, yet the way in which they are modulated across states is not well understood. Moreover, it remains unclear whether these interactions are similarly affected in aging regardless of cognitive state. In this study, we investigated age-related differences in functional interactions among the DMN, FPN and DAN during rest and the Multi-Source Interference task (MSIT)...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28579971/altered-default-mode-network-on-resting-state-fmri-in-children-with-infantile-spasms
#12
Ya Wang, Yongxin Li, Huirong Wang, Yanjun Chen, Wenhua Huang
Infantile spasms (IS) syndrome is an age-dependent epileptic encephalopathy, which occurs in children characterized by spasms, impaired consciousness, and hypsarrhythmia. Abnormalities in default mode network (DMN) might contribute to the loss of consciousness during seizures and cognitive deficits in children with IS. The purpose of the present study was to investigate the changes in DMN with functional connectivity (FC) and amplitude of low-frequency fluctuation (ALFF), the two methods to discover the potential neuronal underpinnings of IS...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28575483/that-s-me-in-the-spotlight-neural-basis-of-individual-differences-in-self-consciousness
#13
Irene de Caso, Giulia Poerio, Elizabeth Jefferies, Jonathan Smallwood
A long-standing literature implicates activity within the default mode network (DMN) to processes linked to the self. However, contemporary work suggests that other large-scale networks networks might also be involved. For instance, goal-directed autobiographical planning requires positive functional connectivity (FC) between DMN and frontoparietal control (FPCN) networks. The present study examined the inter-relationship between trait self-focus (measured via a self-consciousness scale; SCS), incidental memory in a self-reference paradigm, and resting state FC of large-scale networks...
May 29, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28573719/n-nitrosamines-induced-infertility-and-hepatotoxicity-in-male-rabbits
#14
S A Sheweita, Y Y El Banna, M Balbaa, I A Abdullah, H E Hassan
N-nitrosamines are widely spread environmental pollutants of well-known toxicity and carcinogenicity in various animal species. These compounds are metabolically activated by cytochrome P450 system predominantly in the liver and in other tissues into more active metabolites leading to generation of both alkylating agents that alkylate DNA and reactive oxygen species. In the current study, we investigated the influence of four types of N-nitrosamines that are commonly present in the environment [methyethylnitrosamine, (MEN), diethylnitrosamine (DEN), diphenylnitroasamine (DPN) and dimethylnitrosamine (DMN)] on both livers and testes of male rabbits through assessment of 17 β-hydroxysteroid dehydrogenase (17 β-HSD) activity...
June 2, 2017: Environmental Toxicology
https://www.readbyqxmd.com/read/28566724/aberrant-intra-and-internetwork-functional-connectivity-in-depressed-parkinson-s-disease
#15
Luqing Wei, Xiao Hu, Yajing Zhu, Yonggui Yuan, Weiguo Liu, Hong Chen
Much is known concerning the underlying mechanisms of Parkinson's disease (PD) with depression, but our understanding of this disease at the neural-system level remains incomplete. This study used resting-state functional MRI (rs-fMRI) and independent component analysis (ICA) to investigate intrinsic functional connectivity (FC) within and between large-scale neural networks in 20 depressed PD (dPD) patients, 35 non-depressed PD (ndPD) patients, and 34 healthy controls (HC). To alleviate the influence caused by ICA model order selection, this work reported results from analyses at 2 levels (low and high model order)...
May 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28559843/altered-functional-connectivity-of-cognitive-related-cerebellar-subregions-in-alzheimer-s-disease
#16
Weimin Zheng, Xingyun Liu, Haiqing Song, Kuncheng Li, Zhiqun Wang
Alzheimer's disease (AD) is the most common cause of dementia. Previous studies have found disrupted resting state functional connectivities (rsFCs) in various brain networks in the AD patients. However, few studies have focused on the rsFCs of the cerebellum and its sub-regions in the AD patients. In this study, we collected resting-state functional magnetic resonance imaging (rs-fMRI) data including 32 AD patients and 38 healthy controls (HCs). We selected two cognitive-related subregions of the cerebellum as seed region and mapped the whole-brain rsFCs for each subregion...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28553199/aberrant-functional-connectivity-architecture-in-participants-with-chronic-insomnia-disorder-accompanying-cognitive-dysfunction-a-whole-brain-data-driven-analysis
#17
Ran Pang, Yafeng Zhan, Yunling Zhang, Rongjuan Guo, Jialin Wang, Xiao Guo, Yong Liu, Zhiqun Wang, Kuncheng Li
Objectives: Although it is widely observed that chronic insomnia disorder (CID) is associated with cognitive impairment, the neurobiological mechanisms underlying this remain unclear. Prior neuroimaging studies have confirmed that a close correlation exists between functional connectivity and cognitive impairment. Based on this observation, in this study we used resting-state functional magnetic resonance imaging (rs-fMRI) to study the relationship between whole brain functional connectivity and cognitive function in CID...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28553118/psychosis-in-parkinsonism-an-unorthodox-approach
#18
REVIEW
Marco Onofrj, Danilo Carrozzino, Aurelio D'Amico, Roberta Di Giacomo, Stefano Delli Pizzi, Astrid Thomas, Valeria Onofrj, John-Paul Taylor, Laura Bonanni
Psychosis in Parkinson's disease (PD) is currently considered as the occurrence of hallucinations and delusions. The historical meaning of the term psychosis was, however, broader, encompassing a disorganization of both consciousness and personality, including behavior abnormalities, such as impulsive overactivity and catatonia, in complete definitions by the International Classification of Diseases-10 (ICD-10) and the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). Our review is aimed at reminding that complex psychotic symptoms, including impulsive overactivity and somatoform disorders (the last being a recent controversial entity in PD), were carefully described in postencephalitic parkinsonism (PEP), many decades before dopaminergic treatment era, and are now described in other parkinsonisms than PD...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28552562/the-central-anorexigenic-mechanism-of-amylin-in-japanese-quail-coturnix-japonica-involves-pro-opiomelanocortin-calcitonin-receptor-and-the-arcuate-nucleus-of-the-hypothalamus
#19
Jingwei Yuan, Elizabeth R Gilbert, Mark A Cline
Amylin is a 37-amino acid peptide hormone that exerts anorexigenic effects in humans and animals. We demonstrated that central injection of amylin into chicks affected feeding and related behaviors via the hypothalamus and brainstem, although the molecular mechanisms remained elusive. Thus, the objective of this study was to investigate the molecular mechanisms underlying anorexigenic effects of amylin in 7 day-old Japanese quail. Food but not water intake was reduced after intracerebroventricular amylin injection, and the behavior analysis indicated that this was associated with decreased food pecks and preening...
August 2017: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/28549650/effect-of-picalm-rs3851179-polymorphism-on-the-default-mode-network-function-in-mild-cognitive-impairment
#20
Ding-Ming Sun, Hai-Feng Chen, Qi-Long Zuo, Fan Su, Feng Bai, Chun-Feng Liu
Alterations in default mode network (DMN) functional connectivity (FC) might accompany the dysfunction of Alzheimer's disease (AD). Indeed, episodic memory impairment is a hallmark of AD, and mild cognitive impairment (MCI) has been associated with a high risk for AD. Phosphatidylinositol-binding clathrin assembly protein (PICALM) (rs3851179) has been associated with AD; in particular, the A allele may serve a protective role, while the G allele serves as a strong genetic risk factor. Therefore, the identification of genetic polymorphisms associated with the DMN is required in MCI subjects...
May 23, 2017: Behavioural Brain Research
keyword
keyword
100116
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"