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Cow milk allergy

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https://www.readbyqxmd.com/read/28516451/evidence-that-eating-baked-egg-or-milk-influences-egg-or-milk-allergy-resolution-a-systematic-review
#1
REVIEW
R Lambert, K E C Grimshaw, B Ellis, J Jaitly, G Roberts
BACKGROUND: It has been proposed that the frequent ingestion of baked hen's egg or cow's milk accelerates the resolution of hen's egg or cow's milk allergy. This practice is being introduced into clinical practice. OBJECTIVE: To systematically review the evidence to determine whether the introduction of baked hen's egg or cow's milk into the diet of children with hen's egg or cow's milk allergies respectively leads to a larger proportion of children outgrowing these allergies than expected...
May 17, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28504580/intragastric-administration-of-lactobacillus-casei-bl23-induces-regulatory-foxp3-ror%C3%AE-t-t-cells-subset-in-mice
#2
N G Cortes-Perez, D Lozano-Ojalvo, M A Maiga, S Hazebrouck, K Adel-Patient
Many studies have highlighted the immunomodulatory properties of the probiotic strain Lactobacillus casei BL23. Recently, we demonstrated the ability of this strain to modulate the Th2-oriented immune response in a mouse model of cow's milk allergy based on the induction of a Th17-biased immune response. The probiotic function of L. casei has been also linked to gut-microbiota modifications which could been potentially involved in the immune regulation; however, its precise mechanism of action remains poorly understood...
May 15, 2017: Beneficial Microbes
https://www.readbyqxmd.com/read/28486398/bioactive-peptides-in-animal-food-products
#3
REVIEW
Marzia Albenzio, Antonella Santillo, Mariangela Caroprese, Antonella Della Malva, Rosaria Marino
Proteins of animal origin represent physiologically active components in the human diet; they exert a direct action or constitute a substrate for enzymatic hydrolysis upon food processing and consumption. Bioactive peptides may descend from the hydrolysis by digestive enzymes, enzymes endogenous to raw food materials, and enzymes from microorganisms added during food processing. Milk proteins have different polymorphisms for each dairy species that influence the amount and the biochemical characteristics (e...
May 9, 2017: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28466667/side-effects-and-their-impact-on-the-success-of-milk-oral-immunotherapy-oit-in-children
#4
Francesca Mori, Antonella Cianferoni, Alice Brambilla, Simona Barni, Lucrezia Sarti, Neri Pucci, Maurizio de Martino, Elio Novembre
Oral immunotherapy (OIT) has been introduced as a new immune-modulating treatment under investigation for food allergies. The aim of our study was to evaluate the success of OIT in a cohort of children with milk allergy. These children underwent OIT in a clinical practice and were followed for up to ten years. The secondary endpoint was to describe the main adverse events during OIT and compare them to those reported in the literature. Eighty-two milk-allergic children started OIT. According to the OIT endpoint reached after one year, all of the children enrolled in the study were divided into four groups: complete desensitization; partial desensitization; step down; and stop groups...
March 1, 2017: International Journal of Immunopathology and Pharmacology
https://www.readbyqxmd.com/read/28460991/glycation-of-%C3%AE-lactoglobulin-under-dynamic-high-pressure-microfluidization-treatment-effects-on-ige-binding-capacity-and-conformation
#5
Yuan Chen, Zongcai Tu, Hui Wang, Lu Zhang, Xiaomei Sha, Juanjuan Pang, Ping Yang, Guangxian Liu, Wenhua Yang
The effects of dynamic high-pressure microfluidization (DHPM) (80, 120, and 160MPa) treatment and glycation with galactose on the IgE-binding capacity and conformation of β-lactoglobulin (β-Lg) were investigated. The binding capacity of immunoglobulin E (IgE) from patients' sera with cow's milk allergy on β-Lg glycated with galactose decreased after DHPM treatment. β-Lg treated after different DHPM methods and pressures yielded a significant discrepancy in IgE-binding capacity. When β-Lg was pretreated by DHPM, the IgE-binding capacity of β-Lg-galactose conjugates decreased with increasing pressure; however, the conjugates showed higher IgE-binding capacity at 120MPa than that at 80 and 160MPa when the β-Lg-galactose mixture was treated by DHPM...
November 2016: Food Research International
https://www.readbyqxmd.com/read/28459985/cow-s-milk-allergy-in-infancy-and-later-development-of-juvenile-idiopathic-arthritis-a-register-based-case-control-study
#6
Miika Arvonen, J Lauri, Virta, Tytti Pokka, Liisa Kröger, Paula Vähäsalo
We have examined the association between cow's milk allergy (CMA) and juvenile idiopathic arthritis (JIA). The material for this case-control-study was collected from national registers of all children born between 2000 and 2010 in Finland and diagnosed with JIA (n = 1,298) and age-, gender- and place-matched controls (n = 5,179). We identified 235 children with CMA, 66 of these also had JIA. A conditional logistic regression analysis was performed to evaluate the association between CMA and JIA and to test whether exposure to antibiotics would be a covariate for this association...
April 28, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28449395/breast-milk-iga-to-foods-has-different-epitope-specificity-than-serum-iga-evidence-for-entero-mammary-link-for-food-specific-iga
#7
Antti E Seppo, Emma M Savilahti, M Cecilia Berin, Hugh A Sampson, Kirsi M Järvinen
BACKGROUND: We have previously shown that maternal cow's milk (CM) elimination results in down-regulation of CM-specific IgA antibody levels in BM, but not in serum, suggesting that an entero-mammary link may exist for food-specific antibody-secreting cells. OBJECTIVE: We sought to investigate whether food-specific IgA epitope profiles differ intra-individually between mother's serum and BM. We also examined how infants' food epitope-specific IgA develops in early infancy and the relationship of IgA epitope recognition with development of cow's milk allergy (CMA)...
April 27, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28417624/cow-s-milk-desensitization-in-anaphylactic-patients-a-new-personalized-dose-method
#8
Delara Babaie, Mohammad Nabavi, Saba Arshi, Mehrnaz Mesdaghi, Zahra Chavoshzadeh, Mohammad Hasan Bemanian, Mitra Tafakori, Mehrdad Amirmoini, Hosein Esmailzadeh, Rasoul Molatefi, Mahsa Rekabi, Nadieh Akbarpour, Farimah Masoumi, Morteza Fallahpour
Cow's milk allergy (CMA) is the most frequent food allergy in children and oral immunotherapy (OIT) is a promising approach for treatment of patients. The most challenging cases are anaphylactic with coexisting asthma and proposing safe protocols is crucial especially in high risk groups. Considering that CMA varies among patients, an individualized OIT protocol would be beneficial to achieve a safer and more efficient method of desensitization. 18 children more than 3 years of age with IgE-mediated CMA were enrolled...
February 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/28416249/prognostic-accuracy-of-clinical-signs-and-diagnostic-tests-in-cow-s-milk-allergy-in-newborns
#9
Gregor Nosan, Maja Jakic, Miha Jager, Darja Paro-Panjan
BACKGROUND: The aim of the study was to explore the correlation between clinical signs and confirmatory tests for cow's milk allergy (CMA) in the neonatal period and their relation to family history and the occurrence of food allergies in the postneonatal period. METHODS: The medical documentation of 361 newborns with suspected CMA and exclusion of other comorbidities was analyzed. The correlations between clinical signs and methods to confirm CMA [elevated levels of total immunoglobulin E (IgE) and/or specific IgE for cow's milk, improvement after the introduction of a cow's milk-free diet and positive challenge procedure] were studied...
March 27, 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/28401052/pooled-analysis-of-the-cow-s-milk-related-symptom-score-comiss%C3%A2-as-a-predictor-for-cow-s-milk-related-symptoms
#10
Yvan Vandenplas, Philippe Steenhout, Anette Järvi, Anne-Sophie Garreau, Rajat Mukherjee
PURPOSE: The diagnosis of cow's milk (CM) allergy is a challenge. The Cow's Milk-related-Symptom-Score (CoMiSS™) was developed to offer primary health care providers a reliable diagnostic tool for CM related symptoms. The predictive prospective value of the CoMiSS™ was evaluated in three clinical trials. METHODS: Pooled analyses of the three studies were conducted based on regressing the results of the month-1 challenge test on the month-1 CoMiSS™, adjusting for baseline CoMiSS™ using a logistic regression model...
March 2017: Pediatric Gastroenterology, Hepatology & Nutrition
https://www.readbyqxmd.com/read/28398201/frequency-and-course-of-eosinophilic-esophagitis-during-oral-immunotherapy-for-cow-s-milk-allergy-in-a-series-of-57-children
#11
E Gómez Torrijos, Y Mendez Díaz, L Moreno Lozano, A M Extremera Ortega, J Borja Segade, J F Feo Brito, J Rodríguez Sánchez, R García Rodríguez
No abstract text is available yet for this article.
2017: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/28389301/development-of-anaphylactic-cow-s-milk-allergy-following-cow-s-milk-elimination-for-eosinophilic-esophagitis-in-a-teenager
#12
Lianne Soller, Christopher Mill, Vishal Avinashi, Timothy Teoh, Edmond S Chan
No abstract text is available yet for this article.
April 4, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28387917/cow-milk-induced-allergies-cma-and-asthma-in-new-born
#13
W Wang, H-W Wu, J-F Liu
The article "Cow milk induced allergies (CMA) and asthma in new born" by W. Wang, H.-W. Wu, J.-F. Liu, published in Eur Rev Med Pharmacol Sci 2016; 20 (6): 1008-1014 has been withdrawn.
March 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28375580/inflammatory-events-during-food-protein-induced-enterocolitis-syndrome-reactions
#14
Valentina Pecora, Giusi Prencipe, Rocco Valluzzi, Lamia Dahdah, Antonella Insalaco, Antonella Cianferoni, Fabrizio De Benedetti, Alessandro Fiocchi
BACKGROUND: An increasing number of infants are diagnosed with food protein induced enterocolitis syndrome (FPIES), a non-IgE-mediated food allergy. Until now, T-cell, food-specific mechanisms have been hypothesized. METHODS: 16 children (11M, 5F), affected by FPIES from cow's milk, wheat, fruit, rice and others, experienced 25 acute episodes managed at our Emergency Department (ED) and eight FPIES reactions during oral food challenges (OFC). We compared the laboratory data in resting conditions, in absence of infectious diseases, with data collected during the 25 acute ED episodes (blood samples drawn at 2 to 12 hours) and the eight positive OFCs (three samples at 2, 6 and 12 hours)...
April 4, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28364406/component-resolved-diagnostics-in-thai-children-with-cow-s-milk-and-egg-allergy
#15
Wipa Jessadapakorn, Pasuree Sangsupawanich, Natthakul Wootipoom, Oranart Suddeaugrai, Araya Yuenyongviwat
BACKGROUND AND OBJECTIVE: Component-resolved diagnostics (CRD) have garnered a lot of attention in recent years in the diagnosis of food allergies. We aimed to investigate sensitization against cow's milk and egg white components, and to study the clinical usefulness of serum food-specific immunoglobulin E (sIgE) to cow's milk and egg white components in Thai children with cow's milk and egg allergies. METHOD: Children with IgE-mediated cow's milk and/or egg allergy were enrolled...
April 1, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28346705/performance-of-a-polymer-coated-silicon-microarray-for-simultaneous-detection-of-food-allergen-specific-ige-and-igg4
#16
Steven Sievers, Marina Cretich, Paola Gagni, Birgit Ahrens, Galina Grishina, Hugh Sampson, Bodo Niggemann, Marcella Chiari, Kirsten Beyer
BACKGROUND: Microarray-based component-resolved diagnostics (CRD) has become an accepted tool to detect allergen specific IgE-sensitization towards hundreds of allergens in parallel from one drop of serum. Nevertheless specificity and sensitivity as well as a simultaneous detection of allergen specific IgG4, as a potential parameter for tolerance development, remain to be optimized. OBJECTIVE: We applied the recently introduced silicon chip coated with a functional polymer named copoly(DMA-NAS-MAPS) to the simultaneous detection of food allergen specific IgE and IgG4, and compared it with ImmunoCAP and ImmunoCAP ISAC...
March 27, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28345783/natural-tolerance-development-in-cow-s-milk-allergic-children-ige-and-igg4-epitope-binding
#17
Jean Christoph Caubet, Jing Lin, Birgit Ahrens, Gustavo Gimenez, Luda Bardina, Bodo Niggemann, Hugh A Sampson, Kirsten Beyer
BACKGROUND: Although most of cow's milk (CM) allergic children will outgrow their allergy, the pathomechanism of the natural development of tolerance remains poorly understood. It has been suggested that the balance between milk specific IgE and IgG4 plays a major role. OBJECTIVE: We aimed to investigate differences in IgE and IgG4 antibody binding to cow's milk (CM) epitopes between patients with persistent CM allergy (CMA) and those that naturally became tolerant...
March 27, 2017: Allergy
https://www.readbyqxmd.com/read/28345135/eliminating-cows-milk-but-not-wheat-barley-or-rye-increases-the-risk-of-growth-deceleration-and-nutritional-inadequacies
#18
Jetta Tuokkola, Päivi Luukkainen, Jaakko Nevalainen, Suvi Ahonen, Jorma Toppari, Jorma Ilonen, Riitta Veijola, Mikael Knip, Suvi M Virtanen, Minna Kaila
AIM: Our study examined the growth and nutritional intake of children on milk and, or, wheat, barley or rye elimination diets. METHODS: This was a nested case-control study within the Finnish Type 1 Diabetes Prediction and Prevention Study. It investigated 295 children born in the Tampere University Hospital area between 1997-2004 on a diet without cows' milk and, or, wheat, barley or rye due to food allergies and 265 matched controls. Nutritional intake was recorded with three-day food records at the ages of one, two and three years...
March 27, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28343843/%C3%AE-s1-casein-elucidate-major-t-cell-responses-in-cow-s-milk-allergy
#19
L Diego Archila, Fatima S Khan, Nupur Bhatnagar, David Robinson, Mary L Farrington, William W Kwok
Cow's milk allergy (CMA) is increasing in prevalence, affecting approximately 4% of children. Cow's milk (CM) is a common cause of fatal/ near fatal anaphylactic reactions. Understanding of CM-specific CD4+ T-cells responses to milk allergens should help elucidate the pathological mechanisms of persistent CMA. Milk allergen epitopes specific T-cells were examined in CMA subjects. Frequencies and phenotypes of these T-cells were found to be different between older and younger subjects.
March 23, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28337229/allergic-enteritis-in-children
#20
REVIEW
Mieczysława Czerwionka-Szaflarska, Ewa Łoś-Rycharska, Julia Gawryjołek
The gastrointestinal form of food allergy is very common in children. The most frequently observed types are allergic proctitis and proctocolitis. In most cases the symptoms subside within the first 2 months of life. The babies seem healthy, and the only abnormality is a small amount of blood in stool. Symptoms can also include small intestine inflammation and colitis. Patients may present with irritability, abdominal pain, flatulence, colic, postprandial vomiting, chronic diarrhoea, and hindered physical development...
2017: Przegla̜d Gastroenterologiczny
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