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https://www.readbyqxmd.com/read/28813695/risk-based-remediation-of-polluted-sites-a-critical-perspective
#1
REVIEW
Saranya Kuppusamy, Kadiyala Venkateswarlu, Mallavarapu Megharaj, Srinithi Mayilswami, Yong Bok Lee
Sites contaminated with chemical pollutants represent a growing challenge, and remediation of such lands is of international concern. Risk-based land management (RBLM) is an emerging approach that integrates risk assessment practices with more traditional site-specific investigations and remediation activities. Developing countries are yet to adopt RBLM strategies for remediation. RBLM is considered to be practical, scientifically defensible and cost-efficient. However, it is inherently limited by: firstly, the accuracy of risk assessment models used; secondly, ramifications of the fact that they are more likely to leave contamination in place; and thirdly, uncertainties involved and having to consider the total concentrations of all contaminants in soils that overestimate the potential risks from exposure to the contaminants...
August 9, 2017: Chemosphere
https://www.readbyqxmd.com/read/28813646/antihelminthic-drug-niclosamide-inhibits-cip2a-and-reactivates-tumor-suppressor-protein-phosphatase-2a-in-non-small-cell-lung-cancer-cells
#2
Myeong-Ok Kim, Min Ho Choe, Yi Na Yoon, Jiyeon Ahn, Minjin Yoo, Kwan-Young Jung, Sungkwan An, Sang-Gu Hwang, Jeong Su Oh, Jae-Sung Kim
Protein phosphatase 2A (PP2A) is a critical tumor suppressor complex responsible for the inactivation of various oncogenes. Recently, PP2A reactivation has emerged as an anticancer strategy. Cancerous inhibitor of protein phosphatase 2A (CIP2A), an endogenous inhibitor of PP2A, is upregulated in many cancer cells, including non-small cell lung cancer (NSCLC) cells. We demonstrated that the antihelminthic drug niclosamide inhibited the expression of CIP2A and reactivated the tumor suppressor PP2A in NSCLC cells...
August 13, 2017: Biochemical Pharmacology
https://www.readbyqxmd.com/read/28813362/people-have-feelings-exercise-psychology-in-paradigmatic-transition
#3
REVIEW
Panteleimon Ekkekakis
Exercise psychology has yet to produce intervention methods capable of increasing exercise and physical activity behavior in a sustainable manner. This situation is forcing a critical reevaluation of current conceptual models, especially the assumption that behavioral decisions are driven solely by the rational evaluation of information. Like other behavioral sciences, exercise psychology is transitioning to dual-process models that acknowledge the importance of non-reflective processes. Emerging evidence suggests that the pleasure or displeasure experienced during exercise may influence subsequent physical activity...
August 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28813354/new-directions-in-the-psychology-of-optimal-performance-in-sport-flow-and-clutch-states
#4
REVIEW
Christian Swann, Lee Crust, Stewart A Vella
Csikszentmihalyi's conceptualisation of flow is the primary framework for understanding the psychology of optimal experience and performance in sport. However, emerging evidence suggests a more dynamic, multi-state perspective. This review focuses primarily on recent studies highlighting a second, overlapping 'clutch' state which - in addition to flow - underlies optimal performance in sport. We also examine how the nature of goals ('open' or 'fixed') athletes pursue influence the experience of flow and clutch respectively...
August 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28813350/anxiety-and-performance-perceptual-motor-behavior-in-high-pressure-contexts
#5
REVIEW
Arne Nieuwenhuys, Raôul Rd Oudejans
When the pressure is on and anxiety levels increase it is not easy to perform well. In search of mechanisms explaining the anxiety-performance relationship, we revisit the integrated model of anxiety and perceptual-motor performance (Nieuwenhuys and Oudejans, 2012) and provide a critical review of contemporary literature. While there is increasing evidence that changes in attentional control affect the execution of goal-directed action, based on our model and emerging evidence from different scientific disciplines, we argue for a more integrated, process-based approach...
August 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28813335/cultural-sport-psychology-a-critical-review-of-empirical-advances
#6
REVIEW
Tatiana V Ryba
Despite a long standing assertion that sociocultural domain is one of the factors constituting human psychological phenomena, sport psychological science has only recently begun to examine culture as the principal basis of physical activity and sport participants' behaviour, wellbeing, engagement, and performance outcomes. Emphasizing the centrality of culture in bringing meaning to athlete careers and life projects, I summarise empirical literature explicitly positioned within cultural sport psychology (CSP)...
August 2017: Current Opinion in Psychology
https://www.readbyqxmd.com/read/28813178/centriole-biogenesis-from-identifying-the-characters-to-understanding-the-plot
#7
Niccolò Banterle, Pierre Gönczy
The centriole is a beautiful microtubule-based organelle that is critical for the proper execution of many fundamental cellular processes, including polarity, motility, and division. Centriole biogenesis, the making of this miniature architectural wonder, has emerged as an exemplary model to dissect the mechanisms governing the assembly of a eukaryotic organelle. Centriole biogenesis relies on a set of core proteins whose contributions to the assembly process have begun to be elucidated. Here, we review current knowledge regarding the mechanisms by which these core characters function in an orderly fashion to assemble the centriole...
August 16, 2017: Annual Review of Cell and Developmental Biology
https://www.readbyqxmd.com/read/28812836/understanding-internal-accountability-in-nigeria-s-routine-immunization-system-perspectives-from-government-officials-at-the-national-state-and-local-levels
#8
Daniel J Erchick, Asha S George, Chukwunonso Umeh, Chizoba Wonodi
BACKGROUND: Routine immunization coverage in Nigeria has remained low, and studies have identified a lack of accountability as a barrier to high performance in the immunization system. Accountability lies at the heart of various health systems strengthening efforts recently launched in Nigeria, including those related to immunization. Our aim was to understand the views of health officials on the accountability challenges hindering immunization service delivery at various levels of government...
December 10, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28812707/the-rise-and-fall-of-malaria-under-land-use-change-in-frontier-regions
#9
Andres Baeza, Mauricio Santos-Vega, Andrew P Dobson, Mercedes Pascual
Land-use change is the main force behind ecological and social change in many countries around the globe; it is primarily driven by resource needs and external economic incentives. Concomitantly, transformations of the land are the main drivers for the emergence and re-emergence of malaria. An understanding of malaria population dynamics in transforming landscapes is lacking, despite its relevance for developmental and public health policies. We develop a mathematical model that couples malaria epidemiology with the socio-economic and demographic processes that occur in a landscape undergoing land-use change...
March 20, 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/28812457/from-half-dead-to-being-free-resistance-to-hiv-stigma-self-disclosure-and-support-for-pmtct-hiv-care-among-couples-living-with-hiv-in-kenya
#10
Sydney A Spangler, Lisa L Abuogi, Eliud Akama, Elizabeth A Bukusi, Anna Helova, Pamela Musoke, Wafula Z Nalwa, Thomas A Odeny, Maricianah Onono, Iris Wanga, Janet M Turan
In sub-Saharan Africa, self-disclosure of HIV-positive status may be a pivotal action for improving access to prevention of mother-to-child transmission services. However, understanding of HIV stigma and disclosure, and their effects on demand for care remains incomplete - particularly in the current context of new antiretroviral therapy guidelines. The purpose of this study was to explore these issues among self-disclosed couples living in southwest Kenya. We conducted 38 in-depth interviews with HIV-positive pregnant or postpartum women and their male partners...
August 16, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/28812318/the-development-and-flexibility-of-gaze-alternations-in-bonobos-and-chimpanzees
#11
Kelsey Lucca, Evan L MacLean, Brian Hare
Infants' early gaze alternations are one of their first steps towards a sophisticated understanding of the social world. This ability, to gaze alternate between an object of interest and another individual also attending to that object, has been considered foundational to the development of many complex social-cognitive abilities, such as theory of mind and language. However, to understand the evolution of these abilities, it is important to identify whether and how gaze alternations are used and develop in our closest living relatives, bonobos (Pan paniscus) and chimpanzees (Pan troglodytes)...
August 15, 2017: Developmental Science
https://www.readbyqxmd.com/read/28812265/oxytocin-and-olfaction
#12
Lars-Lennart Oettl, Wolfgang Kelsch
Social signals are identified through processing in sensory systems to trigger appropriate behavioral responses. Social signals are received primarily in most mammals through the olfactory system. Individuals are recognized based on their unique blend of odorants. Such individual recognition is critical to distinguish familiar conspecifics from intruders and to recognize offspring. Social signals can also trigger stereotyped responses like mating behaviors. Specific sensory pathways for individual recognition and eliciting stereotyped responses have been identified both in the early olfactory system and its connected cortices...
August 16, 2017: Current Topics in Behavioral Neurosciences
https://www.readbyqxmd.com/read/28811221/is-the-hype-around-the-reproductive-health-claims-of-maca-lepidium-meyenii-walp-justified
#13
REVIEW
Shruti Beharry, Michael Heinrich
ETHNOPHARMACOLOGICAL RELEVANCE: Maca - Lepidium meyenii Walp has been cultivated and used by Andean people for over 1,300 to 2000 years in Peru as food and medicine. Starting in the late 1990's it has developed into an important herbal medicine in China and is now cultivated there widely, too. AIM OF STUDY: This study aims to provide an insight into the emergence of maca on the global market as an alternative remedy to treat reproductive health related problems in both men and women and to critically assess these health claims...
August 12, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28811143/nadph-oxidases-as-drug-targets-and-biomarkers-in-neurodegenerative-diseases-what-is-the-evidence
#14
REVIEW
Silvia Sorce, Roland Stocker, Tamara Seredenina, Rikard Holmdahl, Adriano Aguzzi, Adriano Chio, Antoine Depaulis, Freddy Heitz, Peter Olofsson, Tomas Olsson, Venceslas Duveau, Despina Sanoudou, Sara Skosgater, Antonia Vlahou, Dominique Wasquel, Karl-Heinz Krause, Vincent Jaquet
Neurodegenerative disease are frequently characterized by microglia activation and/or leukocyte infiltration in the parenchyma of the central nervous system and at the molecular level by increased oxidative modifications of proteins, lipids and nucleic acids. NADPH oxidases (NOX) emerged as a novel promising class of pharmacological targets for the treatment of neurodegeneration due to their role in oxidant generation and presumably in regulating microglia activation. The unique function of NOX is the generation of superoxide anion (O2(•-)) and hydrogen peroxide (H2O2)...
August 12, 2017: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/28811051/patient-blood-management-in-the-intensive-care-unit
#15
REVIEW
Aryeh Shander, Mazyar Javidroozi, Gregg Lobel
Patient Blood Management underscores a fundamental shift from a product-centered approach to a patient-centric approach through timely application of evidence-based medical and surgical concepts designed to maintain hemoglobin concentration, optimize hemostasis, and minimize blood loss in an effort to improve patient outcome. In this concept, allogeneic blood transfusion is not viewed as the treatment of default for anemic patients, but one among many treatment modalities that should be weighed based on its merits-potentials risks and benefits-for the individual patient in the context of other alternatives...
July 31, 2017: Transfusion Medicine Reviews
https://www.readbyqxmd.com/read/28811044/learning-how-to-teach-one-a-needs-assessment-of-the-state-of-faculty-development-within-the-consortium-of-the-american-college-of-surgeons-accredited-education-institutes
#16
John T Paige, Nehal N Khamis, Jeffrey B Cooper
BACKGROUND: Developing faculty competencies in curriculum development, teaching, and assessment using simulation is critical for the success of the Consortium of the American College of Surgeons Accredited Education Institutes program. The state of and needs for faculty development in the Accredited Education Institute community are unknown currently. The Faculty Development Committee of the Consortium of the Accredited Education Institutes conducted a survey of Accredited Education Institutes to ascertain what types of practices are used currently, with what frequency, and what needs are perceived for further programs and courses to guide the plan of action for the Faculty Development Committee...
August 12, 2017: Surgery
https://www.readbyqxmd.com/read/28810974/factors-affecting-organizational-commitment-in-navy-corpsmen
#17
Stephanie Booth-Kewley, Renée G Dell'Acqua, Cynthia J Thomsen
BACKGROUND: Organizational commitment is a psychological state that has a strong impact on the likelihood that employees will remain with an organization. Among military personnel, organizational commitment is predictive of a number of important outcomes, including reenlistment intentions, job performance, morale, and perceived readiness. Because of the unique challenges and experiences associated with military service, it may be that organizational commitment is even more critical in the military than in civilian populations...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28810846/personality-traits-and-suicide-attempts-with-and-without-psychiatric-disorders-analysis-of-impulsivity-and-neuroticism
#18
Bo Bi, Wei Liu, Die Zhou, Xu Fu, Xiaoxia Qin, Jiali Wu
BACKGROUND: There is a critical need for empirical data concerning the association of personality traits and attempted suicide with and without psychiatric disorders in mainland China. The objective of the present study is to provide such data by determining the prevalence of psychiatric disorders and analyzing the levels of impulsivity and neuroticism among people who have attempted suicide, and to examine the association between these personality traits and suicide attempt in people with or without psychiatric disorders...
August 15, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28810453/-health-psychology-or-psychology-for-health-a-history-of-psychologists-engagement-with-health-in-south-africa
#19
Jeffery Yen, Oriana Vaccarino
In contrast to the institutionalization of health psychology in North America and Europe, much psychological work on health issues in South Africa emerged as part of a critical revitalization of South African psychology as a whole, coinciding with the dismantling of Apartheid and global shifts in health discourse. The field's development reflects attempts to engage with urgent health problems in the context of rapid sociopolitical changes that followed democratic transition in the 1990s, and under new conditions of knowledge production...
May 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28809180/exploring-socio-technical-insights-for-safe-nursing-handover
#20
Ming Chao Wong, Kwang Chien Yee, Paul Turner
Current efforts to improve nursing handover frequently use prescriptive approaches based on research evidence of handover issues within a single nursing ward or nursing specialty. Despite reported handover improvement, few studies adequately consider the transferability of results to other nursing handover environments or acknowledge the unique attributes that supported sustained improvement. With the increasing diffusion of electronic tools it has become even more critical to ensure that socio-technical issues that may impact on the quality and safety of nursing handovers are identified...
2017: Studies in Health Technology and Informatics
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