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Austin Rallis, Kelene A Fercho, Taylor J Bosch, Lee A Baugh
Tool use is associated with three visual streams-dorso-dorsal, ventro-dorsal, and ventral visual streams. These streams are involved in processing online motor planning, action semantics, and tool semantics features, respectively. Little is known about the way in which the brain represents virtual tools. To directly assess this question, a virtual tool paradigm was created that provided the ability to manipulate tool components in isolation of one another. During functional magnetic resonance imaging (fMRI), adult participants performed a series of virtual tool manipulation tasks in which vision and movement kinematics of the tool were manipulated...
January 31, 2018: Neuropsychologia
X T Wang, Ryan N Reed, Lee A Baugh, Kelene A Fercho
We tested a novel hypothesis that glucose taste acts as a signal for resource acquisition, motivating preference for immediate rewards while actual glucose ingestion prompts resource conservation, promoting future-orientated self-regulation. In Study 1, participants were engaged in a delay-discounting task and a grip-control task before and after a beverage intervention (glucose drink, water drink, or glucose mouth-rinse). Glucose ingestion decreased delay discounting, making larger-and-later rewards more attractive...
February 1, 2018: Appetite
Kathleen A Brown-Rice, Jamie L Scholl, Kelene A Fercho, Kami Pearson, Noah A Kallsen, Gareth E Davies, Erik A Ehli, Seth Olson, Amy Schweinle, Lee A Baugh, Gina L Forster
A significant proportion of college students are adult children of an alcoholic parent (ACoA), which can confer greater risk of depression, poor self-esteem, alcohol and drug problems, and greater levels of college attrition. However, some ACoA are resilient to these negative outcomes. The goal of this study was to better understand the psychobiological factors that distinguish resilient and vulnerable college-aged ACoAs. To do so, scholastic performance and psychological health were measured in ACoA college students not engaged in hazardous alcohol use (resilient) and those currently engaged in hazardous alcohol use (vulnerable)...
February 2, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
Kelene Fercho, Lee A Baugh
To lift an object, the motor system must predict the weight of the object and use this information to program appropriate lifting forces. If this prediction is erroneous, people may assign blame for the error to either themselves or an external source-a process called credit assignment. In the present study, we explored the role of credit assignment on weight predictions during a lifting task. Participants were told that the EMG surface electrodes attached to their lifting hand were either part of a "passive" system that recorded muscular activity, or part of an "active" system that would apply energy to the muscle, influencing weight perception...
September 2016: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
Kelene Fercho, Lee A Baugh, Elizabeth K Hanson
PURPOSE: The purpose of this article was to examine the neural mechanisms associated with increases in speech intelligibility brought about through alphabet supplementation. METHOD: Neurotypical participants listened to dysarthric speech while watching an accompanying video of a hand pointing to the 1st letter spoken of each word on an alphabet display (treatment condition) or a scrambled display (control condition). Their hemodynamic response was measured with functional magnetic resonance imaging, using a sparse sampling event-related paradigm...
October 2015: Journal of Speech, Language, and Hearing Research: JSLHR
Kelene Fercho, Lee A Baugh
Although there have been substantial research efforts examining the effect of various rates of change in reaching movements, there has been little to no research devoted to this issue during object manipulation tasks. In force-field and visuomotor adaptation studies, two parallel processes have been identified: first, a fast process that adapts and de-adapts quickly is thought to enable the actor to deal with potentially transient perturbations. Second, a slower, but longer lasting process adapts if these initial perturbations persist over time...
2014: Frontiers in Human Neuroscience
C H R Wallace, I Baczkó, L Jones, M Fercho, P E Light
BACKGROUND AND PURPOSE: The cardiovascular benefits of red wine consumption are often attributed to the antioxidant effects of its polyphenolic constituents, including quercetin, catechin and resveratrol. Inhibition of cardiac voltage-gated sodium channels (VGSCs) is antiarrhythmic and cardioprotective. As polyphenols may also modulate ion channels, and possess structural similarities to several antiarrhythmic VGSC inhibitors, we hypothesised that VGSC inhibition may contribute to cardioprotection by these polyphenols...
November 2006: British Journal of Pharmacology
Michael J Riedel, István Baczkó, Gavin J Searle, Nicola Webster, Matthew Fercho, Lynn Jones, Jessica Lang, Jonathan Lytton, Jason R B Dyck, Peter E Light
The sodium-calcium exchanger (NCX) is a critical mediator of calcium homeostasis. In the heart, NCX1 predominantly operates in forward mode to extrude Ca(2+); however, reverse-mode NCX1 activity during ischemia/reperfusion (IR) contributes to Ca(2+) loading and electrical and contractile dysfunction. IR injury has also been associated with altered fat metabolism and accumulation of long-chain acyl CoA esters. Here, we show that acyl CoAs are novel, endogenous activators of reverse-mode NCX1 activity, exhibiting chain length and saturation dependence, with longer chain saturated acyl moieties being the most effective NCX1 activators...
October 4, 2006: EMBO Journal
C Ellenberger, K-F Schüppel, M Möhring, A Reischauer, M Alex, C-P Czerny, A Fercho, H-A Schoon
Cowpox virus infection associated with a streptococcal septicaemia was diagnosed in a weak German Warmblood filly, born 29 days prematurely, and humanely destroyed on the sixth day of life. At necropsy, ulcerative lesions in the alimentary tract, colitis, polyarthritis and nephritis were observed. Transmission electron microscopical examination of specimens from ulcerative lesions revealed typical orthopox virions. Cowpox virus was unequivocally identified by virological and molecular-biological methods.
January 2005: Journal of Comparative Pathology
David A Eckerman, Kristine Abrahamson, Tammara Ammerman, Heather Fercho, Diane S Rohlman, W Kent Anger
INTRODUCTION: Interactive computer-based safety instruction (CBI) was given to 73 workers in the food services department of an urban hospital. RESULTS: Post-test accuracy (95%) improved significantly (p < or = 0.0001) from the pre-test (74.5 %), d = 1.09. Generalization was confirmed by increased accuracy in answering questions, posed on-the-job, that required application of knowledge to the work setting (from 46% to 79%; p < 0.0001). Problematic kitchen conditions such as puddles increased slightly after training, but adjustment for increasing production/workload revealed an overall post-training decline in problems from 0...
2004: Journal of Safety Research
No abstract text is available yet for this article.
August 1957: American Journal of Ophthalmology
David A Eckerman, Christine A Lundeen, Andrew Steele, Heather L Fercho, Tammara A Ammerman, W Kent Anger
A tenet of behavioral education is that interactive training produces superior retention compared with reading. However, this has not often been directly tested and never with practical occupational information in working adults. Adults from diverse occupational backgrounds learned the principles of proper respiratory protection presented (a) in a book, (b) on a computer monitor, (c) through interactive computerized training consisting of textual information and illustrative pictures followed by quizzes and feedback, or (d) passively viewing the information and quizzes in Condition c on a computer monitor...
October 2002: Journal of Occupational Health Psychology
R Rojdev, W M Nelson, K J Hart, M C Fercho
The differential criterion-related validity of the MMPI and MMPI-2 and their stability over a 4-month period of time were examined in a university population by correlating the clinical scales with their counterpart SCL-90-R factors. Fair to moderate correlations were found on all eight paired MMPI scales and SCL-90-R factors, while only two of eight MMPI-2/SCL-90-R pairings were found to be correlated significantly. Further analyses, however, found no significant differences between these MMPI/SCL-90-R and MMPI-2/SCL-90-R correlations...
May 1994: Journal of Clinical Psychology
W B Kannel, J M Seidman, W Fercho, W P Castelli
No abstract text is available yet for this article.
June 1974: Circulation
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