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Gross Motor

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https://www.readbyqxmd.com/read/29223621/does-observation-of-a-disabled-child-s-action-moderate-action-execution-implication-for-the-use-of-action-observation-therapy-for-patient-rehabilitation
#1
Marie Alsamour, Maxime Gilliaux, Anne Renders, Thierry Lejeune, Gaëtan Stoquart, Martin Gareth Edwards
BACKGROUND: Research investigating action observation-execution priming has mainly manipulated congruent versus incongruent action, and aspects of action expertise/capability. More specifically, the literature suggests enhanced performance priming following action observation by actors closely matched to participant expertise. The aim of the present study was to extend the understanding of action expertise effects by investigating action priming in healthy participants after observing a mild hemiparetic child actor versus a neurologically healthy child actor...
November 15, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29223113/comparisons-of-severity-classification-systems-for-oropharyngeal-dysfunction-in-children-with-cerebral-palsy-relations-with-other-functional-profiles
#2
Yu-Ra Goh, Ja Young Choi, Seon Ah Kim, Jieun Park, Eun Sook Park
This study aimed to investigate the relationships between various classification systems assessing the severity of oropharyngeal dysphagia and communication function and other functional profiles in children with cerebral palsy (CP). This is a prospective, cross-sectional, study in a university-affiliated, tertiary-care hospital. We recruited 151 children with CP (mean age 6.11 years, SD 3.42, range 3-18yr). The Eating and Drinking Ability Classification System (EDACS) and the dysphagia scales of Functional Oral Intake Scale (FOIS), Swallow Function Scales (SFS), and Food Intake Level Scale (FILS) were used...
December 6, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29221530/parenting-practices-and-associations-with-development-delays-among-young-children-in-dominican-republic
#3
Omolara Thomas Uwemedimo, Afrin Howlader, Giselina Pierret
BACKGROUND: According to the World Health Organization, >200 million children in low- and middle-income countries experience developmental delays. However, household structure and parenting practices have been minimally explored as potential correlates of developmental delay in low- and middle-income countries, despite potential as areas for intervention. OBJECTIVE: The objective of the study was to examine associations of developmental delays with use of World Health Organization-recommended parenting practices among a clinic-based cohort of children aged 6-60 months attending in La Romana, Dominican Republic...
May 2017: Annals of Global Health
https://www.readbyqxmd.com/read/29220616/interventions-to-improve-or-maintain-lower-limb-function-among-ambulatory-adolescents-with-cerebral-palsy-a-cross-sectional-survey-of-current-practice-in-the-uk
#4
Gerasimos Taflampas, Cherry Kilbride, Wendy Levin, Grace Lavelle, Jennifer M Ryan
OBJECTIVES: To describe physiotherapy management to improve or maintain lower-limb function among adolescents with cerebral palsy, classified in Gross Motor Function Classification System levels I-III, in the United Kingdom (UK). METHODS: A list of interventions was identified using a nominal group technique and developed into a survey, which was distributed to approximately 2,100 pediatric physiotherapists in the UK through the Association of Pediatric Chartered Physiotherapists and a private physiotherapy clinic in London between April and June 2015...
December 8, 2017: Physical & Occupational Therapy in Pediatrics
https://www.readbyqxmd.com/read/29217678/hrpu-2-a-homologue-of-mammalian-hnrnp-u-regulates-synaptic-transmission-by-controlling-the-expression-of-slo-2-potassium-channel-in-c-elegans
#5
Ping Liu, Sijie Jason Wang, Zhao-Wen Wang, Bojun Chen
Slo2 channels are large-conductance potassium channels abundantly expressed in the nervous system. However, it is unclear how their expression level in neurons is regulated. Here we report that HRPU-2, an RNA-binding protein homologous to mammalian hnRNP U, plays an important role in regulating the expression of SLO-2 (a homologue of mammalian Slo2) in C. elegans Loss-of-function (lf) mutants of hrpu-2 were isolated in a genetic screen for suppressors of a sluggish phenotype caused by a hyperactive SLO-2. In hrpu-2(lf) mutants, SLO-2-mediated delayed outward currents in neurons are greatly decreased, and neuromuscular synaptic transmission is enhanced...
December 7, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29215495/caregiver-perceptions-and-health-related-quality-of-life-changes-in-cerebral-palsy-patients-after-spinal-arthrodesis
#6
Amit Jain, Brian Sullivan, Suken A Shah, Amer F Samdani, Burt Yaszay, Michelle C Marks, Paul D Sponseller
STUDY DESIGN: Retrospective analysis of a prospective registryObjective: Our objective was to prospectively assess caregivers' perceptions regarding changes in the health-related quality of life (HRQL) of patients with cerebral palsy (CP) after spinal arthrodesis. We assessed caregiver perceptions from 3 perspectives: 1) qualitative assessment of changes in global quality of life, comfort, and health; 2) relative valuation of spine surgery versus other common interventions in CP patients; and 3) quantitative changes in HRQL scores...
December 5, 2017: Spine
https://www.readbyqxmd.com/read/29214145/bitter-orange-citrus-aurantium-l-extract-subchronic-90-day-safety-study-in-rats
#7
N S Deshmukh, S J Stohs, C C Magar, A Kale, B Sowmya
Bitter orange (Citrus aurantium L.) extracts are widely used in dietary supplements and bitter oranges are used in various juices and food products. p-Synephrine, the primary active constituent, comprises approximately 90% of total protoalkaloids. This study, performed per OECD 408 guidance, examined the 90-day subchronic safety/toxicity of an extract standardized to 50% p-synephrine at doses of 100, 300 and 1000 mg/kg/day to male and female rats. No adverse effects were observed with respect to any of the observed parameters of clinical signs, functional observations of sensory reactivity, grip strength and motor activity, ophthalmology, body weights, hematology, food consumption, urinalysis, organ weights, as well as gross and microscopic pathology at termination at any of the doses in either sex...
2017: Toxicology Reports
https://www.readbyqxmd.com/read/29210832/quality-of-caregiving-is-positively-associated-with-neurodevelopment-during-the-first-year-of-life-among-hiv-exposed-uninfected-children-in-uganda
#8
Itziar Familiar, Shalean M Collins, Alla Sikorskii, Horacio Ruisenor-Escudero, Barnabas Natamba, Paul Bangirana, Elizabeth M Widen, Daniel Achidri, Harriet Achola, Daniel Onen, Michael Boivin, Sera L Young
OBJECTIVE: We sought to evaluate if maternal characteristics and infant developmental milieu were predictive of early cognitive development in HIV-exposed uninfected (HEU) and un-exposed uninfected (HU) infants in Uganda. DESIGN: Longitudinal pregnancy study. METHODS: Ugandan women (n=228) were enrolled into the Postnatal Nutrition and Psychosocial Health Outcomes (PostNAPS) study with a 2:1 HIV-uninfected:infected ratio. Maternal socio-demographic, perceived social support, and depressive symptomatology were assessed...
November 27, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29207820/relationship-between-trunk-control-and-balance-in-children-with-spastic-cerebral-palsy-a-cross-sectional-study
#9
Sivatejaa Panibatla, Vijaya Kumar, Amitesh Narayan
Introduction: Trunk control is impaired in children with Cerebral Palsy (CP) thus influencing their functional balance. However, there is a paucity of literature determining the relationship between trunk control and balance in children with CP. Aim: To find the relationship between trunk control and balance by means of Trunk Control Measurement Scale (TCMS) and Paediatric Balance Scale (PBS). Materials and Methods: Twenty four children {age range 8-14 years, Gross Motor Function Classification System (GMFCS) Level I-III} with spastic CP were recruited and evaluated using TCMS and PBS...
September 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/29206077/radiosurgery-and-stereotactic-radiotherapy-with-cyberknife-system-for-meningioma-treatment
#10
Rossella Di Franco, Valentina Borzillo, Vincenzo Ravo, Sara Falivene, Francesco Jacopo Romano, Matteo Muto, Fabrizio Cammarota, Giuseppe Totaro, Gianluca Ametrano, Sabrina Rossetti, Carla Cavaliere, Carmine D' Aniello, Gelsomina Iovane, Maria Assunta Porricelli, Massimiliano Berretta, Gerardo Botti, Luigi Starace, Enrico La Salvia, Gaetano Facchini, Paolo Muto
Objective The aim of this work was to evaluate the impact of stereotactic radiosurgery/fractionated stereotactic radiotherapy with the Cyberknife system on local disease control, clinical outcome and toxicity in patients with meningioma, according to the site and histological grade of lesion. From January 2013 to April 2017, 52 patients with intracranial meningiomas were treated with the Cyberknife system. Twenty-four patients had undergone previous surgery: 38% gross total resection, 10% subtotal resection; 27 patients underwent no surgery; 22 patients had a recurrence of meningioma...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/29205624/fundamental-movement-skills-and-balance-of-children-with-down-syndrome
#11
C M Capio, T C T Mak, M A Tse, R S W Masters
BACKGROUND: Conclusive evidence supports the importance of fundamental movement skills (FMS) proficiency in promoting physical activity and countering obesity. In children with Down Syndrome (DS), FMS development is delayed, which has been suggested to be associated with balance deficits. This study therefore examined the relationship between FMS proficiency and balance ability in children with DS, with the aim of contributing evidence to programmes that address FMS delay. METHODS: Participants consisted of 20 children with DS (7...
December 5, 2017: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/29201124/does-parent-report-gross-motor-function-level-of-cerebral-palsy-children-impact-on-the-quality-of-life-in-these-children
#12
Marzieh Pashmdarfard, Malek Amini, Reza Shervin Badv, Narges Ghaffarzade Namazi, Mehdi Rassafiani
Objective: The aim of this study was to assess the effect of parent report gross motor function level of cerebral palsy (CP) children on the parent report quality of life of CP children. Materials & Methods: Sampling of this cross-sectional study was done in occupational therapy clinics and CP children's schools in 2016 in Zanjan, Iran. Samples size was 60 CP children aged 6-12 yr and for sampling method, a non-probability convenience was used. For assessing the quality of life of CP children the cerebral palsy quality of life (CP QOL) questionnaire and for assessing the level of gross motor function of CP children the Gross Motor Function Classification System Family Report Questionnaire (GMFCSFRQ) were used...
2017: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/29199381/neurosurgical-management-of-cavernous-malformations-located-at-the-foramen-of-monro
#13
Chengjun Wang, Meng Zhao, Xiaofeng Deng, Jia Wang, Qingming Shu, Zhongli Jiang, Jizong Zhao
Cavernous malformations (CMs) located at the foramen of Monro (FM) are relatively rare benign vascular malformations. Knowledge of FM CM is poor. The aims of this study were to describe the incidence, clinical presentation, radiological features, surgical approaches, and neurological outcomes for FM CM patients and to discuss the treatment strategy for this disease. We present a series of nine FM CM patients (four males, five females; mean age 29.3 years) who were treated at a single neurosurgical center. FM CM accounted for 0...
December 4, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/29196216/a-third-copy-of-the-down-syndrome-cell-adhesion-molecule-dscam-causes-synaptic-and-locomotor-dysfunction-in-drosophila
#14
Simon A Lowe, James J L Hodge, Maria M Usowicz
Down syndrome (DS) is caused by triplication of chromosome 21 (HSA21). It is characterised by intellectual disability and impaired motor coordination that arise from changes in brain volume, structure and function. However, the contribution of each HSA21 gene to these various phenotypes and to the causal alterations in neuronal and synaptic structure and function are largely unknown. Here we have investigated the effect of overexpression of the HSA21 gene DSCAM (Down syndrome cell adhesion molecule), on glutamatergic synaptic transmission and motor coordination, using Drosophila expressing three copies of Dscam1...
November 28, 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/29192871/what-does-the-dap-iq-measure-drawing-comparisons-between-drawing-performance-and-developmental-assessments
#15
Gwendolyn Rehrig, Karin Stromswold
Human figure drawing tasks such as the Draw-a-Person test have long been used to assess intelligence (F. Goodenough, 1926). The authors investigate the skills tapped by drawing and the risk factors associated with poor drawing. Self-portraits of 345 preschool children were scored by raters trained in using the Draw-a-Person Intellectual Ability test (DAP:IQ) rubric (C. R. Reynolds & J. A. Hickman, 2004). Analyses of children's fine motor, gross motor, social, cognitive, and language skills revealed that only fine motor skill was an independent predictor of DAP:IQ scores...
December 1, 2017: Journal of Genetic Psychology
https://www.readbyqxmd.com/read/29191439/effects-of-cerebellar-neuromodulation-in-movement-disorders-a%C3%A2-systematic-review
#16
REVIEW
Carina França, Daniel Ciampi de Andrade, Manoel Jacobsen Teixeira, Ricardo Galhardoni, Valquiria Silva, Egberto Reis Barbosa, Rubens Gisbert Cury
BACKGROUND: The cerebellum is involved in the pathophysiology of many movement disorders and its importance in the field of neuromodulation is growing. OBJECTIVES: To review the current evidence for cerebellar modulation in movement disorders and its safety profile. METHODS: Eligible studies were identified after a systematic literature review of the effects of cerebellar modulation in cerebellar ataxia, Parkinson's disease (PD), essential tremor (ET), dystonia and progressive supranuclear palsy (PSP)...
November 23, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/29190557/prenatal-co-exposure-to-neurotoxic-metals-and-neurodevelopment-in-preschool-children-the-environment-and-childhood-inma-project
#17
Carmen Freire, Esperanza Amaya, Fernando Gil, Mariana F Fernández, Mario Murcia, Sabrina Llop, Ainara Andiarena, Juanjo Aurrekoetxea, Mariona Bustamante, Mònica Guxens, Esteban Ezama, Guillermo Fernández-Tardón, Nicolás Olea
We sought to determine whether prenatal co-exposure to As, Cd, Hg, Mn, and Pb was associated with impaired neurodevelopment in preschool children from the Spanish Environment and Childhood (INMA) Project, using the placenta as exposure matrix. We measured metal levels in placenta tissue samples randomly selected from five of the seven population-based birth cohorts participating in the INMA Project, collected between 2000 and 2008. Neuropsychological assessment of cognitive and motor function was carried through the use of the McCarthy Scales of Children's Abilities (MSCA) at the age of 4-5years...
November 27, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29187755/a-mouse-model-of-the-schizophrenia-associated-1q21-1-microdeletion-syndrome-exhibits-altered-mesolimbic-dopamine-transmission
#18
Jacob Nielsen, Kim Fejgin, Florence Sotty, Vibeke Nielsen, Arne Mørk, Claus T Christoffersen, Leonid Yavich, Jes B Lauridsen, Dorte Clausen, Peter H Larsen, Jan Egebjerg, Thomas M Werge, Pekka Kallunki, Kenneth V Christensen, Michael Didriksen
1q21.1 hemizygous microdeletion is a copy number variant leading to eightfold increased risk of schizophrenia. In order to investigate biological alterations induced by this microdeletion, we generated a novel mouse model (Df(h1q21)/+) and characterized it in a broad test battery focusing on schizophrenia-related assays. Df(h1q21)/+ mice displayed increased hyperactivity in response to amphetamine challenge and increased sensitivity to the disruptive effects of amphetamine and phencyclidine hydrochloride (PCP) on prepulse inhibition...
November 30, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/29186388/walking-gross-motor-development-and-brain-functional-connectivity-in-infants-and-toddlers
#19
Natasha Marrus, Adam T Eggebrecht, Alexandre Todorov, Jed T Elison, Jason J Wolff, Lyndsey Cole, Wei Gao, Juhi Pandey, Mark D Shen, Meghan R Swanson, Robert W Emerson, Cheryl L Klohr, Chloe M Adams, Annette M Estes, Lonnie Zwaigenbaum, Kelly N Botteron, Robert C McKinstry, John N Constantino, Alan C Evans, Heather C Hazlett, Stephen R Dager, Sarah J Paterson, Robert T Schultz, Martin A Styner, Guido Gerig, Bradley L Schlaggar, Joseph Piven, John R Pruett
Infant gross motor development is vital to adaptive function and predictive of both cognitive outcomes and neurodevelopmental disorders. However, little is known about neural systems underlying the emergence of walking and general gross motor abilities. Using resting state fcMRI, we identified functional brain networks associated with walking and gross motor scores in a mixed cross-sectional and longitudinal cohort of infants at high and low risk for autism spectrum disorder, who represent a dimensionally distributed range of motor function...
November 23, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/29186196/the-integration-of-probabilistic-information-during-sensorimotor-estimation-is-unimpaired-in-children-with-cerebral-palsy
#20
Claire Chambers, Taegh Sokhey, Deborah Gaebler-Spira, Konrad P Kording
BACKGROUND: It is important to understand the motor deficits of children with Cerebral Palsy (CP). Our understanding of this motor disorder can be enriched by computational models of motor control. One crucial stage in generating movement involves combining uncertain information from different sources, and deficits in this process could contribute to reduced motor function in children with CP. Healthy adults can integrate previously-learned information (prior) with incoming sensory information (likelihood) in a close-to-optimal way when estimating object location, consistent with the use of Bayesian statistics...
2017: PloS One
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